NO953865L - Bifunksjonelle chelatorer og deres anvendelse i radiofarmasöytiske midler - Google Patents

Bifunksjonelle chelatorer og deres anvendelse i radiofarmasöytiske midler

Info

Publication number
NO953865L
NO953865L NO953865A NO953865A NO953865L NO 953865 L NO953865 L NO 953865L NO 953865 A NO953865 A NO 953865A NO 953865 A NO953865 A NO 953865A NO 953865 L NO953865 L NO 953865L
Authority
NO
Norway
Prior art keywords
compounds
radiopharmaceuticals
preparation
bifunctional chelators
radiodiagnostic
Prior art date
Application number
NO953865A
Other languages
English (en)
Other versions
NO953865D0 (no
Inventor
Ludger Dinkelborg
Sebastian Erber
Gerhard Rohlfs
Paul-Eberhard Schulze
Bernhard Noll
Original Assignee
Diagnostikforschung Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostikforschung Inst filed Critical Diagnostikforschung Inst
Publication of NO953865D0 publication Critical patent/NO953865D0/no
Publication of NO953865L publication Critical patent/NO953865L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det beskrives nye technetium- og rheniumchelatfor- bindelser, fremgangsmåter ved deres fremstilling og radiofarmasøytiske midler som inneholder disse for- bindelser, samt konjugater av disse forbindelser med substanser som selektivt akkumuleres i av sykdom angrepet vev, spesielt peptider og proteiner. Dessuten beskrives fremstillingen av midler som inneholder slike forbindelser samt deres anvendelse ved radio- diagnostiske undersøkelser.
NO953865A 1993-03-31 1995-09-29 Bifunksjonelle chelatorer og deres anvendelse i radiofarmasöytiske midler NO953865L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4311021A DE4311021A1 (de) 1993-03-31 1993-03-31 Bifunktionelle Chelatbildner, deren Technetium- und Rhenium-Komplexe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Mittel
PCT/DE1994/000369 WO1994022491A1 (de) 1993-03-31 1994-03-29 Bifunktionelle chelatbildner und ihre anwendung in der radiopharmazeutik

Publications (2)

Publication Number Publication Date
NO953865D0 NO953865D0 (no) 1995-09-29
NO953865L true NO953865L (no) 1995-11-23

Family

ID=6484685

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953865A NO953865L (no) 1993-03-31 1995-09-29 Bifunksjonelle chelatorer og deres anvendelse i radiofarmasöytiske midler

Country Status (10)

Country Link
EP (1) EP0692979A1 (no)
JP (1) JPH08508261A (no)
KR (1) KR960701667A (no)
AU (1) AU6501594A (no)
CA (1) CA2156618A1 (no)
DE (1) DE4311021A1 (no)
HU (1) HUT72733A (no)
NO (1) NO953865L (no)
NZ (1) NZ263792A (no)
WO (1) WO1994022491A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4310999C2 (de) * 1993-03-31 1996-07-18 Diagnostikforschung Inst Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ XN¶1¶S¶1¶X' für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
DE4311022C2 (de) * 1993-03-31 1996-07-11 Diagnostikforschung Inst Bifunktionelle chalkogenatom-unterbrochene Chelatbildner vom Typ S¶3¶N¶2¶ für radioaktive Isotope und deren Metallkomplexe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
DE4337600A1 (de) * 1993-11-01 1995-05-04 Diagnostikforschung Inst N-Alkyl-Peptidchelatbildner, deren Metallkomplexe mit Radionukliden, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende radiopharmazeutische Zusammesetzungen
US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
EP0826000B1 (en) * 1995-05-10 2002-10-23 Darwin Discovery Limited Peptide compounds which inhibit metalloproteinase and tnf liberation and their therapeutic uses
IL123430A (en) * 1995-10-05 2001-04-30 Darwin Discovery Ltd Theo-converted peptides as inhibitors for metallic proteinases and TNF release
DE19652374A1 (de) * 1996-12-04 1998-06-10 Schering Ag Verwendung von Endothelin-Konjugaten in der Therapie, neue Endothelin-Konjugate, diese enthaltende Mittel, sowie Verfahren zu deren Herstellung
NZ511705A (en) * 2001-05-14 2004-03-26 Horticulture & Food Res Inst Methods and rapid immunoassay device for detecting progesterone and other steroids
EP1469875A1 (en) 2002-01-29 2004-10-27 Wyeth Compositions and methods for modulating connexin hemichannels
CN101648028B (zh) * 2002-05-06 2012-11-21 恩多塞特公司 维生素-定向的显象剂
WO2014007632A1 (en) * 2012-07-06 2014-01-09 Stichting Het Nederlands Kanker Instituut Cysteine protease capturing agents
CN116731101A (zh) 2016-06-01 2023-09-12 雅斯娜 用于治疗多种疾病的n-己酸-l-酪氨酸-l-异亮氨酸-(6)-氨基己酰胺的衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3855239T2 (de) * 1987-07-16 1996-10-31 Nycomed Imaging As Aminocarbonsäure und Derivate
WO1992019274A1 (en) * 1991-05-08 1992-11-12 Mallinckrodt Medical, Inc. Technetium chelates to be used for determining the renal function
JPH0570484A (ja) * 1991-09-12 1993-03-23 Hitachi Chem Co Ltd ペプチドおよびその塩
DE69332470D1 (de) * 1992-02-06 2002-12-12 Biosynthema Inc Liganden zur verbesserung der metallchelatbildungskinetik

Also Published As

Publication number Publication date
AU6501594A (en) 1994-10-24
KR960701667A (ko) 1996-03-28
HU9502858D0 (en) 1995-11-28
NO953865D0 (no) 1995-09-29
CA2156618A1 (en) 1994-10-13
HUT72733A (en) 1996-05-28
EP0692979A1 (de) 1996-01-24
DE4311021A1 (de) 1994-10-27
JPH08508261A (ja) 1996-09-03
NZ263792A (en) 1997-02-24
WO1994022491A1 (de) 1994-10-13

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