NO953651L - Fremgangsmåte for fremstilling av virkestoffholdige beinsementer - Google Patents

Fremgangsmåte for fremstilling av virkestoffholdige beinsementer

Info

Publication number
NO953651L
NO953651L NO953651A NO953651A NO953651L NO 953651 L NO953651 L NO 953651L NO 953651 A NO953651 A NO 953651A NO 953651 A NO953651 A NO 953651A NO 953651 L NO953651 L NO 953651L
Authority
NO
Norway
Prior art keywords
cement
drug
component
amt
opt
Prior art date
Application number
NO953651A
Other languages
English (en)
Other versions
NO953651D0 (no
Inventor
Hanz Werner Franz
Berthold Nies
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO953651D0 publication Critical patent/NO953651D0/no
Publication of NO953651L publication Critical patent/NO953651L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001Use of materials characterised by their function or physical properties
    • A61L24/0015Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/06Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Dental Preparations (AREA)
  • Medicinal Preparation (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)

Abstract

Fremgangsmåte for fremstilling av virkestoffholdige beinsementer så vel som beinerstatningsmaterialer eller implanterbare farmakadepoter fremstilt av disse. Beinsementen er sammensatt av en faststoffkomponent og en flytende komponent. Virkestoffet oppløses i et organisk lsningsmiddel hvis andel ikke overstiger 50 vekt%, basert på den flytende komponent, og denne oppløsning blandes med den flytende komponent eller med faststoffkomponenten.
NO953651A 1994-09-17 1995-09-15 Fremgangsmåte for fremstilling av virkestoffholdige beinsementer NO953651L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4433201A DE4433201A1 (de) 1994-09-17 1994-09-17 Verfahren zur Herstellung von wirkstoffhaltigen Knochenzementen

Publications (2)

Publication Number Publication Date
NO953651D0 NO953651D0 (no) 1995-09-15
NO953651L true NO953651L (no) 1996-03-18

Family

ID=6528499

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953651A NO953651L (no) 1994-09-17 1995-09-15 Fremgangsmåte for fremstilling av virkestoffholdige beinsementer

Country Status (16)

Country Link
US (1) US5797873A (no)
EP (1) EP0701824B1 (no)
JP (1) JPH08103491A (no)
KR (1) KR960009978A (no)
CN (1) CN1126618A (no)
AT (1) ATE194778T1 (no)
AU (1) AU3053195A (no)
CA (1) CA2158402A1 (no)
CZ (1) CZ239095A3 (no)
DE (2) DE4433201A1 (no)
ES (1) ES2149909T3 (no)
HU (1) HUT75249A (no)
NO (1) NO953651L (no)
PL (1) PL310492A1 (no)
SK (1) SK114495A3 (no)
ZA (1) ZA957807B (no)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19641775A1 (de) * 1996-08-22 1998-02-26 Merck Patent Gmbh Verfahren zur Herstellung von wirkstoffhaltigen Knochenzementen
US5932633A (en) * 1997-08-22 1999-08-03 Copytele, Inc. Method for making polymers-coated pigment particles using initiator-treated pigments
SE511087C2 (sv) 1998-05-29 1999-08-02 Bone Support Ab Förfarande för framställning av pulverkomponent till cement för medicinskt bruk, användning av sådan pulverkomponent samt sådan pulverkomponent
SE9900519D0 (sv) 1999-02-17 1999-02-17 Lars Lidgren A method for the preparation of UHMWPE doped with an antioxidant and an implant made thereof
US6689823B1 (en) * 1999-03-31 2004-02-10 The Brigham And Women's Hospital, Inc. Nanocomposite surgical materials and method of producing them
DE19918295C2 (de) * 1999-04-22 2003-09-25 Coripharm Medizinprodukte Gmbh Kompatibles Implantat-Baustein-System in Form eines Baukastensystems für Implantationsmaterialien, Verfahren zur Herstellung derselben und ihre Verwendung
SE520688C2 (sv) * 2000-04-11 2003-08-12 Bone Support Ab Ett injicerbart ersättningsmaterial för benmineral
DE10032220A1 (de) 2000-07-03 2002-01-24 Sanatis Gmbh Magnesium-ammonium-phosphat-Zemente, deren Herstellung und Verwendung
SE517168C2 (sv) 2000-07-17 2002-04-23 Bone Support Ab En komposition för ett injicerbart ersättningsmaterial för benmineral
EP1305055B1 (de) 2000-08-01 2004-04-07 Coripharm Medizinprodukte GmbH & Co. KG. Wirkstoffhaltiges implantat-baustein-system und verfahren zu dessen herstellung
US6800245B1 (en) * 2000-11-28 2004-10-05 Vita Special Purpose Corporation Sterile polymerizable systems and kits and methods of their manufacture and use
EP1228772A1 (en) * 2001-02-01 2002-08-07 AM-Pharma B.V. Novel bone cement containing bioactive agents
DE10129842C1 (de) * 2001-06-15 2003-04-24 Bam Bundesanstalt Matforschung Verfahren zur Herstellung eines bioaktiven Knochenzements und Knochenzement-Kit
SE522098C2 (sv) * 2001-12-20 2004-01-13 Bone Support Ab Ett nytt benmineralsubstitut
US7273523B2 (en) * 2002-06-07 2007-09-25 Kyphon Inc. Strontium-apatite-cement-preparations, cements formed therefrom, and uses thereof
DE10227914A1 (de) * 2002-06-21 2004-01-15 Heraeus Kulzer Gmbh & Co. Kg Pharmazeutische Zubereitung mit retardierender Wirkstofffreisetzung, Verfahren zu ihrer Herstellung und Verwendung
EP2671538A1 (en) 2003-01-16 2013-12-11 Massachusetts General Hospital Methods For Making Oxidation Resistant Polymeric Material
SE0300620D0 (sv) * 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
SE0302983D0 (sv) * 2003-11-11 2003-11-11 Bone Support Ab Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed
CA2564687A1 (en) 2004-04-27 2005-11-10 Kyphon Inc. Bone substitute compositions and method of use
US7833452B2 (en) 2004-05-11 2010-11-16 The General Hospital Corporation Method for making oxidation resistant polymeric material
FR2870129A1 (fr) * 2004-05-14 2005-11-18 Ceravic Sas Soc Par Actions Si Ciment polymere pour la vertebroplastie percutanee
SE527528C2 (sv) 2004-06-22 2006-04-04 Bone Support Ab Anordning för framställning av härdbar massa samt användning av anordningen
DE102004049121B4 (de) * 2004-10-07 2008-01-10 Heraeus Kulzer Gmbh Antibiotikum-/Antibiotika enthaltender PMMA-Knochenzement
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
DE102005023094A1 (de) * 2005-05-13 2006-11-16 Nies, Berthold, Dr. Bioaktiver Knochenzement und seine Herstellung
DE102005033210B4 (de) * 2005-06-22 2008-04-30 Heraeus Kulzer Gmbh Polymethylmethacrylat-Knochenzement
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
US7651701B2 (en) * 2005-08-29 2010-01-26 Sanatis Gmbh Bone cement composition and method of making the same
WO2007106582A2 (en) * 2006-03-15 2007-09-20 Promethean Lifesciences, Inc. Preparation and storage of stable, biologically active materials
US20090186332A1 (en) * 2006-03-15 2009-07-23 Manders Ernest K Preparation and storage of stable, antimicrobially active materials
US7754005B2 (en) * 2006-05-02 2010-07-13 Kyphon Sarl Bone cement compositions comprising an indicator agent and related methods thereof
US7507286B2 (en) * 2006-06-08 2009-03-24 Sanatis Gmbh Self-foaming cement for void filling and/or delivery systems
JP2009544411A (ja) * 2006-07-26 2009-12-17 ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア 骨形成増進組成物
US20080075788A1 (en) * 2006-09-21 2008-03-27 Samuel Lee Diammonium phosphate and other ammonium salts and their use in preventing clotting
US20080195223A1 (en) * 2006-11-03 2008-08-14 Avram Allan Eddin Materials and Methods and Systems for Delivering Localized Medical Treatments
WO2008097855A2 (en) * 2007-02-05 2008-08-14 Dfine, Inc. Bone treatment systems and methods
WO2008109045A2 (en) * 2007-03-02 2008-09-12 Synthes Usa, Llc Bone cement with adapted mechanical properties
DE102007015698B4 (de) * 2007-03-27 2009-05-14 Innotere Gmbh Implantatmaterial auf Basis eines Polymersystems und dessen Verwendung sowie Applikationsset
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
KR20100080503A (ko) * 2007-10-12 2010-07-08 피크 플라스틱 앤 메탈 프로덕츠 (인터내셔널) 리미티드 엇물림형 벽 구조물을 포함하는 웨이퍼 컨테이너
DE102007052116B4 (de) * 2007-10-22 2013-02-21 Heraeus Medical Gmbh Einkomponenten-Knochenzementpasten, deren Verwendung und Verfahren zu deren Aushärtung
DE102007050762B3 (de) * 2007-10-22 2009-05-07 Heraeus Medical Gmbh Pastenförmiger Polymethylmethacrylat-Knochenzement und seine Verwendung
US9445854B2 (en) 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
ES2483996T3 (es) 2008-02-28 2014-08-08 Dfine, Inc. Sistemas y métodos de tratamiento de los huesos
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
US7968616B2 (en) * 2008-04-22 2011-06-28 Kyphon Sarl Bone cement composition and method
CA2772569A1 (en) * 2009-09-01 2011-03-10 Synthes Usa, Llc Bone cement containing bone marrow
US8481065B2 (en) * 2009-12-18 2013-07-09 Howmedica Osteonics Corp. Post irradiation shelf-stable dual paste direct injectable bone cement precursor systems and methods of making same
US9180137B2 (en) 2010-02-09 2015-11-10 Bone Support Ab Preparation of bone cement compositions
CN102781483B (zh) * 2010-03-05 2015-05-06 斯恩蒂斯有限公司 用于骨加强术的骨接合剂系统
US10182973B2 (en) 2010-11-10 2019-01-22 Stryker European Holdings I, Llc Polymeric bone foam composition and method
US10294107B2 (en) 2013-02-20 2019-05-21 Bone Support Ab Setting of hardenable bone substitute
US8962044B2 (en) 2013-07-03 2015-02-24 Vivex Biomedical, Inc. Radiopaque bone repair mixture and method of use
US20160206776A1 (en) * 2013-08-27 2016-07-21 Biomet Manufacturing, Llc Apparatus for producing a doughy bone cement shape
DE102015102210A1 (de) * 2015-02-16 2016-08-18 Heraeus Medical Gmbh Antimykotischer polymerisierbarer Knochenzement und ein Verfahren zu seiner Herstellung

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE207655C (no) *
DE2022117C3 (de) * 1970-05-06 1980-12-11 Scherico Ltd., Luzern (Schweiz) Pulverförmige Ausgangsmischung für die unter Methacrylsäuremethylester-Zusatz erfolgende Herstellung von Knochenzement
DD207655A1 (de) * 1982-03-08 1984-03-14 Dagmar Loesche Vorprodukt zur herstellung eines arzneistoffhaltigen knochenzementvorprodukts
US4554686A (en) * 1984-02-29 1985-11-26 Technical Research Associates, Inc. Polymethylmethacrylate bone cements and methods for preparing such bone cements
US4722948A (en) * 1984-03-16 1988-02-02 Dynatech Corporation Bone replacement and repair putty material from unsaturated polyester resin and vinyl pyrrolidone
DE3513938A1 (de) * 1985-04-18 1986-10-23 Merck Patent Gmbh, 6100 Darmstadt Cytostatikahaltiges pharmakadepot
US4900546A (en) * 1987-07-30 1990-02-13 Pfizer Hospital Products Group, Inc. Bone cement for sustained release of substances
DE4019617A1 (de) * 1990-06-20 1992-01-02 Thera Ges Fuer Patente Implantierbares wirkstoffdepotmaterial
DE4023744A1 (de) * 1990-07-26 1992-02-06 Thera Ges Fuer Patente Verwendung von glasionomerzement fuer gesteuerte gewebsregenerationen

Also Published As

Publication number Publication date
EP0701824A2 (de) 1996-03-20
HU9502712D0 (en) 1995-11-28
EP0701824A3 (de) 1997-06-18
DE4433201A1 (de) 1996-03-21
ES2149909T3 (es) 2000-11-16
ATE194778T1 (de) 2000-08-15
US5797873A (en) 1998-08-25
DE59508580D1 (de) 2000-08-24
SK114495A3 (en) 1996-04-03
KR960009978A (ko) 1996-04-20
CA2158402A1 (en) 1996-03-18
ZA957807B (en) 1996-05-07
NO953651D0 (no) 1995-09-15
EP0701824B1 (de) 2000-07-19
PL310492A1 (en) 1996-03-18
JPH08103491A (ja) 1996-04-23
AU3053195A (en) 1996-04-04
CN1126618A (zh) 1996-07-17
HUT75249A (en) 1997-05-28
CZ239095A3 (en) 1996-04-17

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