NO952017L - Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye derivater og preparater inneholdende derivatene - Google Patents
Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye derivater og preparater inneholdende derivateneInfo
- Publication number
- NO952017L NO952017L NO952017A NO952017A NO952017L NO 952017 L NO952017 L NO 952017L NO 952017 A NO952017 A NO 952017A NO 952017 A NO952017 A NO 952017A NO 952017 L NO952017 L NO 952017L
- Authority
- NO
- Norway
- Prior art keywords
- derivatives
- preparation
- taxane
- preparations containing
- new
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title abstract 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N Furan Chemical compound C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 2
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical compound C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- -1 Imldazole Chemical compound 0.000 abstract 1
- ZCQWOFVYLHDMMC-UHFFFAOYSA-N Oxazole Chemical compound C1=COC=N1 ZCQWOFVYLHDMMC-UHFFFAOYSA-N 0.000 abstract 1
- WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical compound C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 230000000719 anti-leukaemic effect Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 150000001602 bicycloalkyls Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- CTAPFRYPJLPFDF-UHFFFAOYSA-N isoxazole Chemical compound C=1C=NOC=1 CTAPFRYPJLPFDF-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epoxy Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9214023A FR2698363B1 (fr) | 1992-11-23 | 1992-11-23 | Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent. |
PCT/FR1993/001145 WO1994012484A1 (fr) | 1992-11-23 | 1993-11-22 | Nouveau procede de preparation de derives du taxane, nouveaux derives ainsi obtenus et les compositions qui les contiennent |
Publications (2)
Publication Number | Publication Date |
---|---|
NO952017L true NO952017L (no) | 1995-05-22 |
NO952017D0 NO952017D0 (no) | 1995-05-22 |
Family
ID=9435782
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO952017A NO952017D0 (no) | 1992-11-23 | 1995-05-22 | Fremgangsmåte for fremstilling av taxanderivater, de således oppnådde nye derivater og preparater inneholdende derivatene |
Country Status (23)
Country | Link |
---|---|
US (1) | US5606083A (xx) |
EP (1) | EP0669916B1 (xx) |
JP (1) | JPH08503486A (xx) |
KR (1) | KR950704286A (xx) |
AT (1) | ATE148111T1 (xx) |
AU (1) | AU680455B2 (xx) |
CA (1) | CA2149758A1 (xx) |
CZ (1) | CZ131795A3 (xx) |
DE (1) | DE69307730T2 (xx) |
DK (1) | DK0669916T3 (xx) |
ES (1) | ES2096440T3 (xx) |
FI (1) | FI952482A (xx) |
FR (1) | FR2698363B1 (xx) |
GR (1) | GR3022359T3 (xx) |
HU (1) | HUT74069A (xx) |
NO (1) | NO952017D0 (xx) |
NZ (1) | NZ258144A (xx) |
PL (1) | PL309037A1 (xx) |
RU (1) | RU95113421A (xx) |
SK (1) | SK68195A3 (xx) |
TW (1) | TW254938B (xx) |
WO (1) | WO1994012484A1 (xx) |
ZA (1) | ZA938728B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5698582A (en) * | 1991-07-08 | 1997-12-16 | Rhone-Poulenc Rorer S.A. | Compositions containing taxane derivatives |
US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
US5475011A (en) * | 1993-03-26 | 1995-12-12 | The Research Foundation Of State University Of New York | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment |
US5677470A (en) | 1994-06-28 | 1997-10-14 | Tanabe Seiyaku Co., Ltd. | Baccatin derivatives and processes for preparing the same |
CA2170661A1 (en) * | 1995-03-22 | 1996-09-23 | John K. Thottathil | Novel methods for the preparation of taxanes using oaxzolidine intermediates |
US6495579B1 (en) | 1996-12-02 | 2002-12-17 | Angiotech Pharmaceuticals, Inc. | Method for treating multiple sclerosis |
US6515016B2 (en) | 1996-12-02 | 2003-02-04 | Angiotech Pharmaceuticals, Inc. | Composition and methods of paclitaxel for treating psoriasis |
US20030157187A1 (en) * | 1996-12-02 | 2003-08-21 | Angiotech Pharmaceuticals, Inc. | Compositions and methods for treating or preventing inflammatory diseases |
US7288665B1 (en) | 1997-08-18 | 2007-10-30 | Florida State University | Process for selective derivatization of taxanes |
EP1019347B1 (en) | 1997-08-21 | 2003-03-19 | Florida State University | Method for the synthesis of taxanes |
CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
US20040132991A1 (en) * | 2002-10-09 | 2004-07-08 | Phytogen Life Sciences Inc. | Novel taxanes and methods related to use and preparation thereof |
US7202370B2 (en) * | 2003-10-27 | 2007-04-10 | Conor Medsystems, Inc. | Semi-synthesis of taxane intermediates from 9-dihydro-13-acetylbaccatin III |
WO2008033466A2 (en) * | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
FR2986526A1 (fr) * | 2012-02-03 | 2013-08-09 | Sanofi Sa | Procede de preparation de derives du taxol et certains composes intermediaires |
CN104650109B (zh) * | 2013-11-22 | 2019-01-01 | 江苏天士力帝益药业有限公司 | 紫杉烷类化合物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
US5229526A (en) * | 1991-09-23 | 1993-07-20 | Florida State University | Metal alkoxides |
US5227400A (en) * | 1991-09-23 | 1993-07-13 | Florida State University | Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them |
-
1992
- 1992-11-23 FR FR9214023A patent/FR2698363B1/fr not_active Expired - Fee Related
-
1993
- 1993-11-22 ZA ZA938728A patent/ZA938728B/xx unknown
- 1993-11-22 TW TW082109812A patent/TW254938B/zh active
- 1993-11-22 CZ CZ951317A patent/CZ131795A3/cs unknown
- 1993-11-22 HU HU9501500A patent/HUT74069A/hu unknown
- 1993-11-22 JP JP6512841A patent/JPH08503486A/ja active Pending
- 1993-11-22 RU RU95113421/04A patent/RU95113421A/ru unknown
- 1993-11-22 AT AT94900862T patent/ATE148111T1/de not_active IP Right Cessation
- 1993-11-22 DK DK94900862.7T patent/DK0669916T3/da active
- 1993-11-22 US US08/424,512 patent/US5606083A/en not_active Expired - Fee Related
- 1993-11-22 WO PCT/FR1993/001145 patent/WO1994012484A1/fr not_active Application Discontinuation
- 1993-11-22 AU AU55659/94A patent/AU680455B2/en not_active Ceased
- 1993-11-22 CA CA002149758A patent/CA2149758A1/fr not_active Abandoned
- 1993-11-22 PL PL93309037A patent/PL309037A1/xx unknown
- 1993-11-22 EP EP94900862A patent/EP0669916B1/fr not_active Expired - Lifetime
- 1993-11-22 ES ES94900862T patent/ES2096440T3/es not_active Expired - Lifetime
- 1993-11-22 SK SK681-95A patent/SK68195A3/sk unknown
- 1993-11-22 DE DE69307730T patent/DE69307730T2/de not_active Expired - Fee Related
- 1993-11-22 NZ NZ258144A patent/NZ258144A/en unknown
-
1995
- 1995-05-22 NO NO952017A patent/NO952017D0/no unknown
- 1995-05-22 KR KR1019950702091A patent/KR950704286A/ko not_active Application Discontinuation
- 1995-05-22 FI FI952482A patent/FI952482A/fi not_active Application Discontinuation
-
1997
- 1997-01-23 GR GR960403091T patent/GR3022359T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI952482A (fi) | 1995-05-24 |
CA2149758A1 (fr) | 1994-06-09 |
CZ131795A3 (en) | 1995-10-18 |
RU95113421A (ru) | 1997-03-20 |
DE69307730D1 (de) | 1997-03-06 |
AU5565994A (en) | 1994-06-22 |
EP0669916B1 (fr) | 1997-01-22 |
ZA938728B (en) | 1994-06-28 |
KR950704286A (ko) | 1995-11-17 |
HUT74069A (en) | 1996-10-28 |
JPH08503486A (ja) | 1996-04-16 |
HU9501500D0 (en) | 1995-07-28 |
DK0669916T3 (da) | 1997-02-10 |
DE69307730T2 (de) | 1997-06-05 |
FI952482A0 (fi) | 1995-05-22 |
WO1994012484A1 (fr) | 1994-06-09 |
ATE148111T1 (de) | 1997-02-15 |
AU680455B2 (en) | 1997-07-31 |
FR2698363A1 (fr) | 1994-05-27 |
US5606083A (en) | 1997-02-25 |
SK68195A3 (en) | 1995-10-11 |
EP0669916A1 (fr) | 1995-09-06 |
TW254938B (xx) | 1995-08-21 |
GR3022359T3 (en) | 1997-04-30 |
NO952017D0 (no) | 1995-05-22 |
FR2698363B1 (fr) | 1994-12-30 |
NZ258144A (en) | 1996-10-28 |
ES2096440T3 (es) | 1997-03-01 |
PL309037A1 (en) | 1995-09-18 |
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