NO951547L - Fremgangsmåte for fremstilling av krystaller av veksthormon og krystaller fremstilt ved fremgangsmåten - Google Patents
Fremgangsmåte for fremstilling av krystaller av veksthormon og krystaller fremstilt ved fremgangsmåtenInfo
- Publication number
- NO951547L NO951547L NO951547A NO951547A NO951547L NO 951547 L NO951547 L NO 951547L NO 951547 A NO951547 A NO 951547A NO 951547 A NO951547 A NO 951547A NO 951547 L NO951547 L NO 951547L
- Authority
- NO
- Norway
- Prior art keywords
- crystals
- pct
- growth hormone
- date
- alkyl
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 5
- 102000018997 Growth Hormone Human genes 0.000 title abstract 4
- 108010051696 Growth Hormone Proteins 0.000 title abstract 4
- 239000000122 growth hormone Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 125000001624 naphthyl group Chemical class 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9203175A SE9203175D0 (sv) | 1992-10-28 | 1992-10-28 | Growth hormone |
| SE19939302278A SE9302278D0 (sv) | 1992-10-28 | 1993-07-02 | Growth hormone |
| PCT/SE1993/000885 WO1994010192A1 (en) | 1992-10-28 | 1993-10-27 | Process for manufacturing crystals of growth hormone and crystals thereby obtained |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO951547L true NO951547L (no) | 1995-04-24 |
| NO951547D0 NO951547D0 (no) | 1995-04-24 |
| NO320171B1 NO320171B1 (no) | 2005-11-07 |
Family
ID=26661557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19951547A NO320171B1 (no) | 1992-10-28 | 1995-04-24 | Fremgangsmate for fremstilling av krystaller av veksthormon eller funksjonelle derivater derav, krystaller fremstilt ved fremgangsmaten, anvendelse av kjemisk forbindelse for fremstilling av krystallene, suspensjon for injeksjon, torrformulering og depotformulering som omfatter krystallene, anvendelse av krystallene for fremstilling av medikament og fremgangsmate for rensing av veksthormon. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5734026A (no) |
| EP (1) | EP0669934B1 (no) |
| JP (1) | JP3470135B2 (no) |
| AT (1) | ATE174602T1 (no) |
| AU (1) | AU679012B2 (no) |
| CA (1) | CA2147482C (no) |
| DE (1) | DE69322654T2 (no) |
| DK (1) | DK0669934T3 (no) |
| ES (1) | ES2126660T3 (no) |
| FI (1) | FI110609B (no) |
| HK (1) | HK1013299A1 (no) |
| NO (1) | NO320171B1 (no) |
| SE (1) | SE9302278D0 (no) |
| WO (1) | WO1994010192A1 (no) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9302278D0 (sv) * | 1992-10-28 | 1993-07-02 | Kabi Pharmacia Ab | Growth hormone |
| US6500933B1 (en) | 1997-09-05 | 2002-12-31 | Altus Biologics Inc. | Methods of preparing carbohydrate crosslinked glycoprotein crystals |
| ATE397013T1 (de) * | 1997-09-05 | 2008-06-15 | Altus Pharmaceuticals Inc | Kohlenhydrat-vernetzte glykoproteinkristalle |
| US6380357B2 (en) * | 1997-12-16 | 2002-04-30 | Eli Lilly And Company | Glucagon-like peptide-1 crystals |
| US6541606B2 (en) * | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
| JP4417113B2 (ja) * | 2002-02-20 | 2010-02-17 | エミスフェアー・テクノロジーズ・インク | Ｇｌｐ−１分子の投与方法 |
| SE0202719D0 (sv) * | 2002-09-13 | 2002-09-13 | Pharmacia Ab | Process for mfg crystals of growth hormone |
| KR20050090430A (ko) | 2002-12-31 | 2005-09-13 | 알투스 파마슈티컬스 인코포레이티드 | 인간 성장 호르몬 결정 및 이것의 제조 방법 |
| US20060286129A1 (en) * | 2003-12-19 | 2006-12-21 | Emisphere Technologies, Inc. | Oral GLP-1 formulations |
| US7799273B2 (en) | 2004-05-06 | 2010-09-21 | Smp Logic Systems Llc | Manufacturing execution system for validation, quality and risk assessment and monitoring of pharmaceutical manufacturing processes |
| US7444197B2 (en) | 2004-05-06 | 2008-10-28 | Smp Logic Systems Llc | Methods, systems, and software program for validation and monitoring of pharmaceutical manufacturing processes |
| EP1976551A4 (en) * | 2005-12-23 | 2009-12-30 | Altus Pharmaceuticals Inc | COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69125035T2 (de) * | 1990-06-04 | 1997-07-10 | Schering Corp | Verfahren zur herstellung von interferon-alpha-2 kristallen |
| WO1991019742A1 (en) * | 1990-06-15 | 1991-12-26 | Schering Corporation | Crystalline interleukin-4 |
| DK168790D0 (no) * | 1990-07-13 | 1990-07-13 | Novo Nordisk As | |
| US5015627A (en) * | 1990-07-20 | 1991-05-14 | Smithkline Beecham Corporation | Stabilized somatotropin for parenteral administration |
| SE9302278D0 (sv) * | 1992-10-28 | 1993-07-02 | Kabi Pharmacia Ab | Growth hormone |
-
1993
- 1993-07-02 SE SE19939302278A patent/SE9302278D0/xx unknown
- 1993-10-27 EP EP93924266A patent/EP0669934B1/en not_active Expired - Lifetime
- 1993-10-27 JP JP51096494A patent/JP3470135B2/ja not_active Expired - Fee Related
- 1993-10-27 WO PCT/SE1993/000885 patent/WO1994010192A1/en active IP Right Grant
- 1993-10-27 ES ES93924266T patent/ES2126660T3/es not_active Expired - Lifetime
- 1993-10-27 DK DK93924266T patent/DK0669934T3/da active
- 1993-10-27 US US08/424,450 patent/US5734026A/en not_active Expired - Fee Related
- 1993-10-27 AT AT93924266T patent/ATE174602T1/de not_active IP Right Cessation
- 1993-10-27 AU AU54011/94A patent/AU679012B2/en not_active Ceased
- 1993-10-27 CA CA002147482A patent/CA2147482C/en not_active Expired - Fee Related
- 1993-10-27 DE DE69322654T patent/DE69322654T2/de not_active Expired - Fee Related
-
1995
- 1995-04-24 NO NO19951547A patent/NO320171B1/no unknown
- 1995-04-27 FI FI952021A patent/FI110609B/fi active
-
1998
- 1998-12-22 HK HK98114660A patent/HK1013299A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3470135B2 (ja) | 2003-11-25 |
| US5734026A (en) | 1998-03-31 |
| CA2147482C (en) | 2003-09-23 |
| NO320171B1 (no) | 2005-11-07 |
| WO1994010192A1 (en) | 1994-05-11 |
| AU679012B2 (en) | 1997-06-19 |
| AU5401194A (en) | 1994-05-24 |
| DE69322654T2 (de) | 1999-06-17 |
| ATE174602T1 (de) | 1999-01-15 |
| CA2147482A1 (en) | 1994-05-11 |
| ES2126660T3 (es) | 1999-04-01 |
| FI952021A0 (fi) | 1995-04-27 |
| NO951547D0 (no) | 1995-04-24 |
| FI952021A (fi) | 1995-04-27 |
| EP0669934B1 (en) | 1998-12-16 |
| DE69322654D1 (de) | 1999-01-28 |
| FI110609B (fi) | 2003-02-28 |
| SE9302278D0 (sv) | 1993-07-02 |
| HK1013299A1 (en) | 1999-08-20 |
| JPH08505127A (ja) | 1996-06-04 |
| DK0669934T3 (da) | 1999-08-23 |
| EP0669934A1 (en) | 1995-09-06 |
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