NO944917L - Anvendelse av 2-fenyl-3-aroyltiofener for inhibering av ovarial dysgenese, forsinket pubertet eller seksuell infantilisme - Google Patents
Anvendelse av 2-fenyl-3-aroyltiofener for inhibering av ovarial dysgenese, forsinket pubertet eller seksuell infantilismeInfo
- Publication number
- NO944917L NO944917L NO944917A NO944917A NO944917L NO 944917 L NO944917 L NO 944917L NO 944917 A NO944917 A NO 944917A NO 944917 A NO944917 A NO 944917A NO 944917 L NO944917 L NO 944917L
- Authority
- NO
- Norway
- Prior art keywords
- phenyl
- aroylthiophenes
- inhibition
- delayed puberty
- ovarian dysgenesis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Tea And Coffee (AREA)
- Adjustment And Processing Of Grains (AREA)
- Compounds Of Unknown Constitution (AREA)
- Tires In General (AREA)
- Control Of Metal Rolling (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Anvendelse av en forbindelse som har formelen: OCH2CH2¿R2 (D hvor R1 og R3 uavhengig er hydrogen -CHo, -C-(Ci-C<. alkyl), eller -C-Ar, hvor Ar er eventuelt substituert fenyl; R2 er valgt fra gruppen bestående av pyrrolldln, heksametylenlmino og plperldlno; eller et farmaseytisk akseptabelt salt eller solvat derav, for Inhibering av ovarial dysgenese, forsinket pubertet eller seksuell Infantilisme ved administrasjon til et menneske som har behov for behandling av en effektiv mengde av nevnte forbindelse.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/170,946 US5451589A (en) | 1993-12-21 | 1993-12-21 | Methods of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism |
Publications (2)
Publication Number | Publication Date |
---|---|
NO944917D0 NO944917D0 (no) | 1994-12-19 |
NO944917L true NO944917L (no) | 1995-06-22 |
Family
ID=22621923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO944917A NO944917L (no) | 1993-12-21 | 1994-12-19 | Anvendelse av 2-fenyl-3-aroyltiofener for inhibering av ovarial dysgenese, forsinket pubertet eller seksuell infantilisme |
Country Status (19)
Country | Link |
---|---|
US (4) | US5451589A (no) |
EP (1) | EP0662325B1 (no) |
JP (1) | JPH07215867A (no) |
KR (1) | KR950016733A (no) |
CN (1) | CN1107702A (no) |
AT (1) | ATE207748T1 (no) |
AU (1) | AU8153294A (no) |
CA (1) | CA2138500A1 (no) |
CZ (1) | CZ321694A3 (no) |
DE (1) | DE69428877T2 (no) |
DK (1) | DK0662325T3 (no) |
ES (1) | ES2162844T3 (no) |
HU (1) | HUT71228A (no) |
IL (1) | IL112049A0 (no) |
NO (1) | NO944917L (no) |
PT (1) | PT662325E (no) |
RU (1) | RU94045272A (no) |
SI (1) | SI0662325T1 (no) |
ZA (1) | ZA9410097B (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5847007A (en) | 1993-05-13 | 1998-12-08 | Neorx Corporation | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
US5595722A (en) | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5856340A (en) * | 1995-02-28 | 1999-01-05 | Eli Lilly And Company | Method of treating estrogen dependent cancers |
DE19604231A1 (de) * | 1996-01-29 | 1997-07-31 | Schering Ag | Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen |
TW442286B (en) * | 1996-02-28 | 2001-06-23 | Pfizer | New therapeutic uses of estrogen agonists |
IL120266A (en) * | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
AU6959898A (en) * | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
US6054446A (en) | 1997-12-24 | 2000-04-25 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
US6649645B1 (en) | 1998-12-23 | 2003-11-18 | Pharmacia Corporation | Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia |
ES2246234T3 (es) | 1999-05-04 | 2006-02-16 | Strakan International Limited | Glicosidos de androgenos y actividad androgenica de los mismos. |
ES2228958T3 (es) * | 2000-10-25 | 2005-04-16 | Eli Lilly And Company | Procedimiento de inhibicion de cataratas. |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US5075321A (en) * | 1987-03-24 | 1991-12-24 | University Of Pennsylvania | Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes |
US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
-
1993
- 1993-12-21 US US08/170,946 patent/US5451589A/en not_active Expired - Lifetime
-
1994
- 1994-12-19 CA CA002138500A patent/CA2138500A1/en not_active Abandoned
- 1994-12-19 ES ES94309469T patent/ES2162844T3/es not_active Expired - Lifetime
- 1994-12-19 JP JP6314601A patent/JPH07215867A/ja active Pending
- 1994-12-19 CN CN94119729A patent/CN1107702A/zh active Pending
- 1994-12-19 HU HU9403654A patent/HUT71228A/hu unknown
- 1994-12-19 PT PT94309469T patent/PT662325E/pt unknown
- 1994-12-19 EP EP94309469A patent/EP0662325B1/en not_active Expired - Lifetime
- 1994-12-19 AU AU81532/94A patent/AU8153294A/en not_active Abandoned
- 1994-12-19 NO NO944917A patent/NO944917L/no not_active Application Discontinuation
- 1994-12-19 DE DE69428877T patent/DE69428877T2/de not_active Expired - Fee Related
- 1994-12-19 CZ CZ943216A patent/CZ321694A3/cs unknown
- 1994-12-19 SI SI9430406T patent/SI0662325T1/xx unknown
- 1994-12-19 KR KR1019940034924A patent/KR950016733A/ko not_active Application Discontinuation
- 1994-12-19 DK DK94309469T patent/DK0662325T3/da active
- 1994-12-19 AT AT94309469T patent/ATE207748T1/de not_active IP Right Cessation
- 1994-12-19 RU RU94045272/14A patent/RU94045272A/ru unknown
- 1994-12-19 ZA ZA9410097A patent/ZA9410097B/xx unknown
- 1994-12-19 IL IL11204994A patent/IL112049A0/xx unknown
-
1995
- 1995-05-17 US US08/442,918 patent/US5760060A/en not_active Expired - Fee Related
- 1995-05-17 US US08/442,917 patent/US5719165A/en not_active Expired - Fee Related
- 1995-05-17 US US08/442,919 patent/US5843962A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
SI0662325T1 (en) | 2002-06-30 |
JPH07215867A (ja) | 1995-08-15 |
US5843962A (en) | 1998-12-01 |
RU94045272A (ru) | 1996-10-20 |
DK0662325T3 (da) | 2001-12-03 |
EP0662325A2 (en) | 1995-07-12 |
IL112049A0 (en) | 1995-03-15 |
AU8153294A (en) | 1995-06-29 |
US5451589A (en) | 1995-09-19 |
ZA9410097B (en) | 1996-06-19 |
EP0662325B1 (en) | 2001-10-31 |
HU9403654D0 (en) | 1995-02-28 |
NO944917D0 (no) | 1994-12-19 |
US5760060A (en) | 1998-06-02 |
CA2138500A1 (en) | 1995-06-22 |
HUT71228A (en) | 1995-11-28 |
US5719165A (en) | 1998-02-17 |
PT662325E (pt) | 2002-03-28 |
DE69428877T2 (de) | 2002-04-25 |
CN1107702A (zh) | 1995-09-06 |
ES2162844T3 (es) | 2002-01-16 |
DE69428877D1 (de) | 2001-12-06 |
CZ321694A3 (en) | 1995-08-16 |
EP0662325A3 (en) | 1995-10-11 |
KR950016733A (ko) | 1995-07-20 |
ATE207748T1 (de) | 2001-11-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |