NO944853L - Glukagonlignende peptid og insulinotropinderivater - Google Patents

Glukagonlignende peptid og insulinotropinderivater

Info

Publication number
NO944853L
NO944853L NO944853A NO944853A NO944853L NO 944853 L NO944853 L NO 944853L NO 944853 A NO944853 A NO 944853A NO 944853 A NO944853 A NO 944853A NO 944853 L NO944853 L NO 944853L
Authority
NO
Norway
Prior art keywords
derivatives
insulinotropin
truncated
glp
glucagon
Prior art date
Application number
NO944853A
Other languages
English (en)
Norwegian (no)
Other versions
NO944853D0 (no
Inventor
Glenn C Andrews
Gaston O Daumy
Michael L Francoeur
Eric R Larson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO944853D0 publication Critical patent/NO944853D0/no
Publication of NO944853L publication Critical patent/NO944853L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO944853A 1992-06-15 1994-12-14 Glukagonlignende peptid og insulinotropinderivater NO944853L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89907392A 1992-06-15 1992-06-15
PCT/US1993/003388 WO1993025579A1 (en) 1992-06-15 1993-04-14 Glucagon-like peptide and insulinotropin derivatives

Publications (2)

Publication Number Publication Date
NO944853D0 NO944853D0 (no) 1994-12-14
NO944853L true NO944853L (no) 1994-12-14

Family

ID=25410453

Family Applications (1)

Application Number Title Priority Date Filing Date
NO944853A NO944853L (no) 1992-06-15 1994-12-14 Glukagonlignende peptid og insulinotropinderivater

Country Status (19)

Country Link
EP (2) EP0969016A2 (de)
JP (1) JP2575298B2 (de)
KR (1) KR0154880B1 (de)
CN (1) CN1057098C (de)
AU (1) AU671117B2 (de)
BR (1) BR9306551A (de)
CA (1) CA2138161C (de)
CZ (1) CZ315594A3 (de)
FI (1) FI932722L (de)
HR (1) HRP930993A2 (de)
HU (2) HUT64367A (de)
IL (1) IL105928A0 (de)
MX (1) MX9303554A (de)
NO (1) NO944853L (de)
PL (1) PL176007B1 (de)
RU (1) RU2128663C1 (de)
SK (1) SK155694A3 (de)
WO (1) WO1993025579A1 (de)
YU (1) YU41493A (de)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
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US6849708B1 (en) 1986-05-05 2005-02-01 The General Hospital Corporation Insulinotropic hormone and uses thereof
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US5614492A (en) * 1986-05-05 1997-03-25 The General Hospital Corporation Insulinotropic hormone GLP-1 (7-36) and uses thereof
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6284727B1 (en) 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
US5705483A (en) 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
GB9409496D0 (en) 1994-05-12 1994-06-29 London Health Ass Method for improving glycaemic control in diabetes
US5574008A (en) * 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
US5512549A (en) * 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
AU4415796A (en) * 1994-12-07 1996-06-26 Bionebraska, Inc. Production of c-terminal amidated peptides from recombinant protein constructs
US5990077A (en) * 1995-04-14 1999-11-23 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US6184201B1 (en) 1995-04-14 2001-02-06 Nps Allelix Corp. Intestinotrophic glucagon-like peptide-2 analogs
US5834428A (en) 1995-04-14 1998-11-10 1149336 Ontario Inc. Glucagon-like peptide-2 and its therapeutic use
US5747453A (en) 1995-06-06 1998-05-05 Alza Corporation Method for increasing the electrotransport flux of polypeptides
US6333189B1 (en) 1996-06-06 2001-12-25 Alza Corporation Method of making an electrotransport device
US6006753A (en) * 1996-08-30 1999-12-28 Eli Lilly And Company Use of GLP-1 or analogs to abolish catabolic changes after surgery
UA65549C2 (uk) 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
DE69831673C5 (de) 1997-01-07 2015-01-22 Amylin Pharmaceuticals, Llc Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme
CA2283834A1 (en) * 1997-03-31 1998-10-08 James Arthur Hoffmann Glucagon-like peptide-1 analogs
US7157555B1 (en) 1997-08-08 2007-01-02 Amylin Pharmaceuticals, Inc. Exendin agonist compounds
US7223725B1 (en) 1997-11-14 2007-05-29 Amylin Pharmaceuticals, Inc. Exendin agonist compounds
EP1066314B1 (de) 1997-11-14 2007-12-26 Amylin Pharmaceuticals, Inc. Neuartige exendin agonisten
US6380357B2 (en) * 1997-12-16 2002-04-30 Eli Lilly And Company Glucagon-like peptide-1 crystals
FR2777283B1 (fr) * 1998-04-10 2000-11-24 Adir Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent
EP2028269B1 (de) 1998-08-10 2015-10-21 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Differenzierung von nicht Insulin-produzierenden Zellen in Insulin-produzierende Zellen durch GLP-1 oder Exendin-4 und Verwendung
DE69922043T2 (de) * 1998-12-07 2005-11-24 Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. Glp-1 analoge
DK1137666T5 (da) * 1998-12-07 2009-10-05 Univ Tulane GLP-1-analoger
US6514500B1 (en) 1999-10-15 2003-02-04 Conjuchem, Inc. Long lasting synthetic glucagon like peptide {GLP-!}
CN1191273C (zh) 1999-05-17 2005-03-02 康久化学公司 长效促胰岛肽
EP2275557A1 (de) 2000-04-12 2011-01-19 Human Genome Sciences, Inc. Albuminfusionsproteine
CA2430934C (en) 2000-12-01 2011-06-21 Takeda Chemical Industries, Ltd. A method of producing sustained-release preparations of a bioactive substance using high-pressure gas
AU2002228608A1 (en) 2000-12-13 2002-06-24 Eli Lilly And Company Amidated glucagon-like peptide-1
RU2353625C2 (ru) * 2001-10-18 2009-04-27 Бристол-Маерс Сквибб Компани Миметики человеческого глюканоподобного пептида-1 и их применение в лечении диабета и родственных состояний
EP2990417A1 (de) 2001-12-21 2016-03-02 Human Genome Sciences, Inc. Albumin-insulin-fusionsprotein
JP4417113B2 (ja) 2002-02-20 2010-02-17 エミスフェアー・テクノロジーズ・インク Ｇｌｐ−１分子の投与方法
EP1594530A4 (de) 2003-01-22 2006-10-11 Human Genome Sciences Inc Albuminfusionsproteine
US20060286129A1 (en) 2003-12-19 2006-12-21 Emisphere Technologies, Inc. Oral GLP-1 formulations
AU2005203925A1 (en) 2004-01-08 2005-07-21 Theratechnologies Inc. Glucagon-Like Peptide-1 analogs with long duration of action
DK1745078T3 (da) 2004-04-23 2009-10-26 Conjuchem Biotechnologies Inc Fremgangsmåde til oprensning af albuminkonjugater
US8039432B2 (en) 2005-11-09 2011-10-18 Conjuchem, Llc Method of treatment of diabetes and/or obesity with reduced nausea side effect
CA2726894A1 (en) 2008-06-27 2009-12-30 Duke University Therapeutic agents comprising elastin-like peptides
EP2590997B1 (de) * 2010-07-09 2018-04-04 Dana-Farber Cancer Institute, Inc. Stabilisierte insulinotrope peptide und verfahren zu ihrer verwendung
EP2873422A4 (de) 2012-07-10 2015-12-30 Takeda Pharmaceutical Pharmazeutische zubereitung zur injektion
BR112017025000A2 (pt) 2015-05-22 2018-08-07 The Bot Of The Leland Stanford Junior University tratamento de hipoglicemia pós-bariátrica com exendina (9-39)
WO2017210100A1 (en) * 2016-06-02 2017-12-07 Indiana University Research And Technology Corporation Glucagon-like peptide-1-t3 conjugates
DK3541366T3 (da) 2016-11-21 2025-03-03 Amylyx Pharmaceuticals Inc Bufferformuleringer af exendin (9-39)
WO2018165462A1 (en) * 2017-03-08 2018-09-13 Intarcia Therapeutics, Inc Apparatus and methods for administration of a nauseogenic compound from a drug delivery device
HRP20240485T1 (hr) 2017-08-24 2024-07-05 Novo Nordisk A/S Pripravci glp-1 i njihova upotreba
MX2022009844A (es) 2020-02-18 2022-09-05 Novo Nordisk As Composiciones y usos del peptido similar al glucagon-1 (glp-1).

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0464022B1 (de) * 1989-03-20 2000-05-31 The General Hospital Corporation Insulinotropes hormon
EP0512042B1 (de) * 1990-01-24 1998-04-08 BUCKLEY, Douglas I. Glp-1-analoga verwendbar in der diabetesbehandlung
DE69210645T2 (de) * 1991-02-19 1996-11-28 Takeda Chemical Industries, Ltd., Osaka Verfahren zur Herstellung von cysteinfreien Peptiden
DK36392D0 (da) * 1992-03-19 1992-03-19 Novo Nordisk As Anvendelse af kemisk forbindelse
DK36492D0 (da) * 1992-03-19 1992-03-19 Novo Nordisk As Praeparat
DK39892D0 (da) * 1992-03-25 1992-03-25 Bernard Thorens Peptid

Also Published As

Publication number Publication date
FI932722A0 (fi) 1993-06-14
HRP930993A2 (en) 1996-12-31
JP2575298B2 (ja) 1997-01-22
FI932722A7 (fi) 1993-12-16
NO944853D0 (no) 1994-12-14
KR950701937A (ko) 1995-05-17
HUT64367A (en) 1993-12-28
JPH07504679A (ja) 1995-05-25
MX9303554A (es) 1994-06-30
HU211498A9 (en) 1995-11-28
EP0969016A2 (de) 2000-01-05
WO1993025579A1 (en) 1993-12-23
CA2138161C (en) 2003-10-21
CN1085913A (zh) 1994-04-27
YU41493A (sh) 1996-10-18
RU94046251A (ru) 1996-10-27
SK155694A3 (en) 1995-05-10
CZ315594A3 (en) 1995-07-12
CA2138161A1 (en) 1993-12-23
PL176007B1 (pl) 1999-03-31
HU9301739D0 (en) 1993-09-28
AU671117B2 (en) 1996-08-15
CN1057098C (zh) 2000-10-04
EP0646128A1 (de) 1995-04-05
AU4027593A (en) 1994-01-04
BR9306551A (pt) 1998-09-15
FI932722L (fi) 1993-12-16
KR0154880B1 (ko) 1998-10-15
RU2128663C1 (ru) 1999-04-10
IL105928A0 (en) 1993-10-20

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Legal Events

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