NO934470L - Analogifremgangsmaate for fremstilling av terapeutisk aktive, mett ede, heterocykliske carboxamidderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive, mett ede, heterocykliske carboxamidderivater

Info

Publication number
NO934470L
NO934470L NO934470A NO934470A NO934470L NO 934470 L NO934470 L NO 934470L NO 934470 A NO934470 A NO 934470A NO 934470 A NO934470 A NO 934470A NO 934470 L NO934470 L NO 934470L
Authority
NO
Norway
Prior art keywords
saturated
preparation
therapeutically active
analogous procedure
carboxamide derivatives
Prior art date
Application number
NO934470A
Other languages
English (en)
Other versions
NO934470D0 (no
Inventor
Toshiyasu Mase
Hiromu Hara
Hitoshi Nagaoka
Takumi Takahashi
Takeshi Suzuki
Kenichi Tomioka
Toshimitsu Yamada
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of NO934470L publication Critical patent/NO934470L/no
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of NO934470D0 publication Critical patent/NO934470D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO934470A 1987-02-20 1993-12-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive, mettede, heterocyklisk e carboxamidderivater NO934470D0 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP62036950 1987-02-20
JP12525987 1987-05-21
JP24949987 1987-10-01

Publications (2)

Publication Number Publication Date
NO934470L true NO934470L (no) 1988-08-22
NO934470D0 NO934470D0 (no) 1993-12-08

Family

ID=27289284

Family Applications (2)

Application Number Title Priority Date Filing Date
NO880740A NO880740L (no) 1987-02-20 1988-02-19 Fremgangsmaate for fremstilling av mettede heterocykliske carboxamidderivater.
NO934470A NO934470D0 (no) 1987-02-20 1993-12-08 Analogifremgangsmaate for fremstilling av terapeutisk aktive, mettede, heterocyklisk e carboxamidderivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO880740A NO880740L (no) 1987-02-20 1988-02-19 Fremgangsmaate for fremstilling av mettede heterocykliske carboxamidderivater.

Country Status (8)

Country Link
US (1) US4987132A (no)
EP (1) EP0279681A3 (no)
CN (1) CN1030415A (no)
AU (2) AU618726B2 (no)
DK (1) DK86688A (no)
FI (1) FI93113C (no)
HU (1) HUT50335A (no)
NO (2) NO880740L (no)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0350145A3 (en) * 1988-04-28 1990-07-04 Yamanouchi Pharmaceutical Co. Ltd. Pyridylthiazolidine carboxamide derivatives and their intermediates and production of both
DE3928144A1 (de) * 1989-08-25 1991-02-28 Hoechst Ag Zyklische pyridin-2,4- und -2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
NO912475L (no) * 1990-06-27 1991-12-30 Sankyo Co Tiazolidinkarboksylsyreamidderivater med antiallergisk aktivitet, og fremgangsmaate til fremstilling derav.
US5470851A (en) * 1990-06-27 1995-11-28 Sankyo Company, Limited Thiazolidinecarboxylic acid amide derivatives and their therapeutic uses
US5120749A (en) * 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
ATE205084T1 (de) * 1991-03-04 2001-09-15 Ct For Innovative Technology 2,4-diaryl-1,3-dithiolane als platelet activating faktor rezeptorblocker und 5-lipoxygenasehemmer
US5120751A (en) * 1991-03-29 1992-06-09 Abbott Laboratories Benzoylphenyl pyridinylthiazolidine compounds as platelet activating antagonists
US5149704A (en) * 1991-05-03 1992-09-22 Abbott Laboratories Platelet activating antagonists
FR2678265B1 (fr) * 1991-06-27 1994-01-14 Synthelabo Derives de 4-(2-phenylethyl)piperidine, leur preparation et leur application en therapeutique.
EP0524846A1 (fr) * 1991-06-27 1993-01-27 Synthelabo Dérivés de 2-(pipéridin-1-y1) éthanol, leur préparation et leur application en thérapeutique
NO924963L (no) * 1991-12-27 1993-06-28 Sankyo Co Pyridyltiazolidinkarboksylsyreamid-derivater og fremgangsmaate til fremstilling derav
GB9200210D0 (en) * 1992-01-07 1992-02-26 British Bio Technology Compounds
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5530141A (en) * 1992-03-04 1996-06-25 Center For Innovative Technology 2,4-diaryl-1,3-dithiolanes; 2,4-diaryl-1,3-dioxolanes; 2,4-diaryl-1,3-oxathiolanes; and 2,5-diaryl-1,3-oxathiolanes for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
JP3298883B2 (ja) * 1992-06-30 2002-07-08 ポハン アイアン アンド スチール カンパニー リミテッド 強力なpaf拮抗剤としての新規な環式脂質誘導体
US5700817A (en) * 1992-06-30 1997-12-23 Pohang Iron & Steel Co., Ltd. Cyclic lipid derivatives as potent PAF antagonists
AU4566093A (en) * 1992-07-08 1994-01-31 Shell Internationale Research Maatschappij B.V. Piperidine derivatives
ES2152952T3 (es) 1992-07-13 2001-02-16 Millennium Pharm Inc 2,5-diaril tetrahidro-tiofenos, -furanos y analogos para el tratamiento de problemas inflamatorios e inmunes.
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5648486A (en) * 1992-07-13 1997-07-15 Cytomed, Inc. Compounds and methods for the treatment of inflammatory and immune disorders
US5358938A (en) * 1992-07-13 1994-10-25 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
WO1994004523A1 (en) * 1992-08-21 1994-03-03 Japan Tobacco Inc. Dioxacycloalkane compound with renin-inhibiting activity
GB9304919D0 (en) * 1993-03-10 1993-04-28 Celltech Ltd Chemical compounds
US5786354A (en) * 1994-06-21 1998-07-28 Celltech Therapeutics, Limited Tri-substituted phenyl derivatives and processes for their preparation
US6245774B1 (en) 1994-06-21 2001-06-12 Celltech Therapeutics Limited Tri-substituted phenyl or pyridine derivatives
GB9412571D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
GB9412573D0 (en) 1994-06-22 1994-08-10 Celltech Ltd Chemical compounds
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5750565A (en) * 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
GB9523675D0 (en) 1995-11-20 1996-01-24 Celltech Therapeutics Ltd Chemical compounds
GB9622363D0 (en) 1996-10-28 1997-01-08 Celltech Therapeutics Ltd Chemical compounds
US6057329A (en) * 1996-12-23 2000-05-02 Celltech Therapeutics Limited Fused polycyclic 2-aminopyrimidine derivatives
GB9705361D0 (en) 1997-03-14 1997-04-30 Celltech Therapeutics Ltd Chemical compounds
DE69820614T2 (de) * 1997-05-30 2004-09-30 Celltech Therapeutics Ltd., Slough Entzündungshemmende tyrosin-derivate
US6207665B1 (en) * 1997-06-12 2001-03-27 Schering Aktiengesellschaft Piperazine derivatives and their use as anti-inflammatory agents
GB9713087D0 (en) * 1997-06-20 1997-08-27 Celltech Therapeutics Ltd Chemical compounds
US6329372B1 (en) 1998-01-27 2001-12-11 Celltech Therapeutics Limited Phenylalanine derivatives
WO1999043642A1 (en) 1998-02-26 1999-09-02 Celltech Therapeutics Limited Phenylalanine derivatives as inhibitors of alpha4 integrins
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
US6521626B1 (en) 1998-03-24 2003-02-18 Celltech R&D Limited Thiocarboxamide derivatives
GB9811159D0 (en) 1998-05-22 1998-07-22 Celltech Therapeutics Ltd Chemical compounds
GB9811969D0 (en) 1998-06-03 1998-07-29 Celltech Therapeutics Ltd Chemical compounds
GB9812088D0 (en) 1998-06-05 1998-08-05 Celltech Therapeutics Ltd Chemical compounds
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9821222D0 (en) 1998-09-30 1998-11-25 Celltech Therapeutics Ltd Chemical compounds
GB9825652D0 (en) 1998-11-23 1999-01-13 Celltech Therapeutics Ltd Chemical compounds
GB9826174D0 (en) 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
GB9914258D0 (en) 1999-06-18 1999-08-18 Celltech Therapeutics Ltd Chemical compounds
US6534513B1 (en) 1999-09-29 2003-03-18 Celltech R&D Limited Phenylalkanoic acid derivatives
GB9924862D0 (en) * 1999-10-20 1999-12-22 Celltech Therapeutics Ltd Chemical compounds
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
AU2001248553A1 (en) 2000-04-17 2001-10-30 Celltech R And D Limited Enamine derivatives as cell adhesion molecules
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
AU2001267753A1 (en) 2000-07-07 2002-01-21 Celltech R And D Limited Squaric acid derivatives containing a bicyclic heteroaromatic ring as integrin antagonists
WO2002010136A1 (en) 2000-08-02 2002-02-07 Celltech R & D Limited 3-substituted isoquinolin-1-yl derivatives
EP1392662B1 (de) * 2001-05-29 2009-01-07 Bayer Schering Pharma Aktiengesellschaft Cdk inhibitorische pyrimidine, deren herstellung und verwendung als arzneimittel
EP1567490B1 (en) * 2002-12-04 2011-10-05 Virginia Commonwealth University Anti-sickling agents
JP4610480B2 (ja) 2003-03-07 2011-01-12 アステラス製薬株式会社 2,6−ジ置換スチリルを有する含窒素ヘテロ環誘導体
EP1692121A1 (en) 2003-11-18 2006-08-23 University of Tennessee Research Foundation Thiazolidinone amides, thiazolidine carboxylic acid amides, methods of making, and uses thereof
US7119208B2 (en) * 2003-12-03 2006-10-10 Virginia Commonwealth University Anti-sickling agents
BRPI0507500A (pt) * 2004-02-06 2007-06-26 Schering Ag derivados de piperazina inibidores de quimiocina e seus usos para tratar mieloma múltiplo
UY30892A1 (es) 2007-02-07 2008-09-02 Smithkline Beckman Corp Inhibidores de la actividad akt
US8822513B2 (en) 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9029408B2 (en) 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
DK2303021T3 (en) * 2008-06-16 2019-04-08 Univ Tennessee Res Found RELATIONSHIPS FOR TREATING CANCER
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
AR075153A1 (es) * 2009-01-30 2011-03-16 Glaxosmithkline Llc Compuesto hidrocloruro de n-{(1s)-2-amino-1-[(3-fluorofenil)metil]etil)-5-cloro-4-(4-cloro-1-metil-1h-pirazol-5-il)-2- tiofenocarboxamida en forma cristalina, composicion farmaceitica que lo comprende, procedimiento para prepararla, su uso para preparar un medicamento util para tratar o disminuir la
JP5879273B2 (ja) 2010-03-01 2016-03-08 ジーティーエックス・インコーポレイテッド 癌を処置するための化合物
CN104529942B (zh) * 2014-12-10 2018-05-15 天津孚音生物科技发展有限公司 一种伐诺司林的合成方法
AU2019271419B2 (en) 2018-05-17 2022-09-29 Bionomics Limited Pain treating compounds and uses thereof
CN111057735B (zh) * 2020-01-06 2021-10-15 浙江工业大学 一种解淀粉芽孢杆菌酯酶在拆分N-BOC-DL-α-氨基丁酸甲酯中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3592905A (en) 1969-10-30 1971-07-13 Merck & Co Inc Therapeutic methods
FR2356423A1 (fr) 1976-07-01 1978-01-27 Oeriu Simion Derives de l'acide thiazolidinecarboxylique, leur preparation et leur application comme medicaments
AU528115B2 (en) * 1978-04-08 1983-04-14 Santen Pharmaceutical Co. Ltd. Antihypertensive 4-thiazolidine/carboxylic acids
EP0045281B1 (de) * 1980-07-28 1985-05-08 Ciba-Geigy Ag Thiazolinderivate und Verfahren zu ihrer Herstellung
FR2541280B1 (fr) * 1983-01-13 1985-06-21 Rhone Poulenc Sante Nouveaux derives du 1h, 3h-pyrrolo (1,2c) thiazolecarboxamide-7, leur preparation et les medicaments qui les contiennent
JPS6090012A (ja) * 1983-10-24 1985-05-21 Nippon Mining Co Ltd 濾過装置
US4656190A (en) 1983-11-14 1987-04-07 Merck & Co., Inc. Indene derivatives and their use as PAF-antagonists
GB8418424D0 (en) 1984-07-19 1984-08-22 Scras Inhibition of platelets aggregation
EP0178261A3 (en) 1984-10-10 1986-12-30 Sandoz Ag Substituted 2-furanyl or 5-oxo-2-furanyl-alkoxy phosphoryl alkyl cyclimmonium salts
HU200177B (en) * 1985-06-18 1990-04-28 Biogal Gyogyszergyar Process for producing thiazolidinecarboxylic acids and pharmaceutical compositions comprising such compounds
US4621038A (en) 1985-06-24 1986-11-04 Xerox Corporation Photoconductive imaging members with novel symmetrical fluorinated squaraine compounds
DE3531498A1 (de) * 1985-09-04 1987-03-05 Bayer Ag Dihydropyridin-2-hydroxyamine, verfahren zur herstellung und ihre verwendung in arzneimitteln
IT1196485B (it) * 1986-07-14 1988-11-16 Zambon Spa Derivati dell'acido tiazolidin-4-carbossilico ad attivita' farmaceutica
JPS63225373A (ja) * 1986-07-24 1988-09-20 Sumitomo Pharmaceut Co Ltd 新規チアゾリジン−4−オン誘導体およびその酸付加塩
DE3635744A1 (de) * 1986-10-21 1988-04-28 Bayer Ag Substituierte aminoketale

Also Published As

Publication number Publication date
FI93113B (fi) 1994-11-15
FI880757A (fi) 1988-08-21
DK86688A (da) 1988-08-22
FI880757A0 (fi) 1988-02-18
EP0279681A2 (en) 1988-08-24
NO934470D0 (no) 1993-12-08
AU1401392A (en) 1992-06-25
EP0279681A3 (en) 1989-11-15
NO880740L (no) 1988-08-22
CN1030415A (zh) 1989-01-18
AU618726B2 (en) 1992-01-09
FI93113C (fi) 1995-02-27
AU1208088A (en) 1988-08-25
DK86688D0 (da) 1988-02-19
AU646156B2 (en) 1994-02-10
HUT50335A (en) 1990-01-29
NO880740D0 (no) 1988-02-19
US4987132A (en) 1991-01-22

Similar Documents

Publication Publication Date Title
NO934470L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive, mett ede, heterocykliske carboxamidderivater
NO177387C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive imidazo-kondenserte, 6-leddede, heterocykliske forbindelser
FI96861C (fi) Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
NO861481L (no) Analogifremgangsmaate for fremstilling av farmasoeytisk aktive heterocykliske amid-derivater.
FI905941A (fi) Menetelmä terapeuttisesti käyttökelpoisten heterosyklisten 2-asyyliaminotiatsolijohdannaisten valmistamiseksi
NO853293L (no) Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater.
FI91152B (fi) Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
NO169900C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive (ih-azol-1-ylmetyl)substituerte benzotriazolderivater
NO176319C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive furanderivater
NO176275C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridazinonderivater
FI896249A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten 7-oksabisykloheptyylisubstituoitujen heterosyklisten amidiprostaglandiinijohdannaisten valmistamiseksi
NO178068C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive tiazolidindionderivater
NO176713C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-aminopyridinderivater
NO178543C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive benzopyranderivater
NO173334C (no) Analogifremgangsm}te for fremstilling av terapeutisk aktive alkylaminoalkylenderivater 2H-1-benzopyraner
NO172849C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazol- og oksazol-derivater
FI93444B (fi) Menetelmä terapeuttisesti aktiivisten dihydropyridiinijohdannaisten valmistamiseksi
NO178698C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive glycerolderivater
NO884175D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater.
NO167923C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive peptidsubstituerte heterocykliske forbindelser
NO169652C (no) Analogifremgangsmaate til fremstilling av terapeutisk aktive guaninderivater
NO173606C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno- triazolo-diazepin-derivater
NO174463C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater
NO177263C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive pyridinderivater
NO173330C (no) Anologifremgangsm}te for fremstilling av terapeutisk aktive pyrrolidin-derivater