NO932120L - Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling - Google Patents
Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstillingInfo
- Publication number
- NO932120L NO932120L NO932120A NO932120A NO932120L NO 932120 L NO932120 L NO 932120L NO 932120 A NO932120 A NO 932120A NO 932120 A NO932120 A NO 932120A NO 932120 L NO932120 L NO 932120L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- drugs containing
- biphenyl derivatives
- methods
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Abstract
Oppfinnelsen angår bifenylderivater med den generelle formel (I) hvor A til E og x er som definert i patentkrav l, deres stereoisomerer, innbefattet deres blandinger og deres salter, spesielt deres fysiologisk akseptable salter med uorganiske eller organiske syrer som oppviser verdifulle egenskaper, fortrinnsvis aggregasjonshemmende virkninger, legemidler som inneholder disse forbindelsene og fremgangs- måter for deres fremstilling.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4219158A DE4219158A1 (de) | 1992-06-11 | 1992-06-11 | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
NO932120D0 NO932120D0 (no) | 1993-06-10 |
NO932120L true NO932120L (no) | 1993-12-13 |
Family
ID=6460811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO932120A NO932120L (no) | 1992-06-11 | 1993-06-10 | Bifenylderivater, legemidler inneholdende disse, og fremgangsmaate for deres fremstilling |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0574808A1 (no) |
JP (1) | JPH0673038A (no) |
KR (1) | KR940005554A (no) |
CN (1) | CN1080917A (no) |
AU (1) | AU4120193A (no) |
CA (1) | CA2098158A1 (no) |
DE (1) | DE4219158A1 (no) |
FI (1) | FI932649A (no) |
HU (1) | HU9301700D0 (no) |
IL (1) | IL105976A0 (no) |
MX (1) | MX9303466A (no) |
NO (1) | NO932120L (no) |
PL (1) | PL299260A1 (no) |
ZA (1) | ZA934090B (no) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT825184E (pt) * | 1993-03-29 | 2001-11-30 | Astrazeneca Ab | Derivados heterociclicos como inibidores de agregacao de plaquetas |
US5753659A (en) * | 1993-03-29 | 1998-05-19 | Zeneca Limited | Heterocyclic compouds |
ZW4194A1 (en) * | 1993-03-29 | 1994-12-21 | Zeneca Ltd | Heterocyclic compounds |
US5652242A (en) * | 1993-03-29 | 1997-07-29 | Zeneca Limited | Heterocyclic derivatives |
US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
DE4424974A1 (de) * | 1994-07-15 | 1996-01-18 | Thomae Gmbh Dr K | Harnstoff- und Carbaminsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
DE19636689A1 (de) | 1996-09-10 | 1998-03-12 | Boehringer Ingelheim Kg | Neue Benzamidinderivate |
ES2218866T3 (es) * | 1997-11-20 | 2004-11-16 | Teijin Limited | Derivados de bifenilamida. |
DE19819548A1 (de) | 1998-04-30 | 1999-11-04 | Merck Patent Gmbh | Biphenylderivate |
AU2868601A (en) * | 2000-01-27 | 2001-08-07 | Ribotargets Ltd | Biaryl compounds, their preparation and their use in therapy |
US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
JP2008516989A (ja) * | 2004-10-19 | 2008-05-22 | コンパス ファーマシューティカルズ リミティド ライアビリティ カンパニー | 組成物及び抗腫瘍剤としてのその使用 |
CA2659682C (en) | 2006-06-26 | 2010-12-21 | The Procter & Gamble Company | Prolyl hydroxylase inhibitors and methods of use |
EP3251671A1 (en) | 2011-06-06 | 2017-12-06 | Akebia Therapeutics Inc. | Compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
NO2686520T3 (no) | 2011-06-06 | 2018-03-17 | ||
PT3007695T (pt) | 2013-06-13 | 2024-03-07 | Akebia Therapeutics Inc | Composições e métodos para tratamento de anemia |
PE20160945A1 (es) | 2013-11-15 | 2016-09-26 | Akebia Therapeutics Inc | Formas solidas de acido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acetico, composiciones, y usos de las mismas |
CA2974691A1 (en) | 2015-01-23 | 2016-07-28 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
IL292262B2 (en) | 2015-04-01 | 2024-02-01 | Akebia Therapeutics Inc | Formulation of an oral administration form of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid |
AU2019265629A1 (en) | 2018-05-09 | 2021-01-07 | Akebia Therapeutics, Inc. | Process for preparing 2-((5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)amino)acetic acid |
US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE4102024A1 (de) * | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
DE69203797T2 (de) * | 1991-06-11 | 1996-02-08 | Ciba Geigy Ag | Amidino-Verbindungen, ihre Herstellung und Verwendung als Arzneimittel. |
DE4127404A1 (de) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1992
- 1992-06-11 DE DE4219158A patent/DE4219158A1/de not_active Withdrawn
-
1993
- 1993-06-08 EP EP93109190A patent/EP0574808A1/de not_active Ceased
- 1993-06-09 PL PL93299260A patent/PL299260A1/xx unknown
- 1993-06-10 ZA ZA934090A patent/ZA934090B/xx unknown
- 1993-06-10 MX MX9303466A patent/MX9303466A/es unknown
- 1993-06-10 NO NO932120A patent/NO932120L/no unknown
- 1993-06-10 FI FI932649A patent/FI932649A/fi not_active Application Discontinuation
- 1993-06-10 HU HU9301700A patent/HU9301700D0/hu unknown
- 1993-06-10 CN CN93106962A patent/CN1080917A/zh active Pending
- 1993-06-10 JP JP5138438A patent/JPH0673038A/ja active Pending
- 1993-06-10 KR KR1019930010494A patent/KR940005554A/ko not_active Application Discontinuation
- 1993-06-10 IL IL93105976A patent/IL105976A0/xx unknown
- 1993-06-10 CA CA002098158A patent/CA2098158A1/en not_active Abandoned
- 1993-06-11 AU AU41201/93A patent/AU4120193A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU4120193A (en) | 1993-12-23 |
CN1080917A (zh) | 1994-01-19 |
ZA934090B (en) | 1994-12-11 |
CA2098158A1 (en) | 1993-12-12 |
PL299260A1 (en) | 1994-03-07 |
NO932120D0 (no) | 1993-06-10 |
MX9303466A (es) | 1994-01-31 |
HU9301700D0 (en) | 1993-09-28 |
DE4219158A1 (de) | 1993-12-16 |
JPH0673038A (ja) | 1994-03-15 |
FI932649A (fi) | 1993-12-12 |
FI932649A0 (fi) | 1993-06-10 |
EP0574808A1 (de) | 1993-12-22 |
IL105976A0 (en) | 1993-10-20 |
KR940005554A (ko) | 1994-03-21 |
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