ZA934090B - Biphenyl derivatives pharmaceutical compositions containing these compounds and processes for preparing them - Google Patents
Biphenyl derivatives pharmaceutical compositions containing these compounds and processes for preparing themInfo
- Publication number
- ZA934090B ZA934090B ZA934090A ZA934090A ZA934090B ZA 934090 B ZA934090 B ZA 934090B ZA 934090 A ZA934090 A ZA 934090A ZA 934090 A ZA934090 A ZA 934090A ZA 934090 B ZA934090 B ZA 934090B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparing
- compounds
- processes
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
- C07C257/10—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
- C07C257/18—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4219158A DE4219158A1 (de) | 1992-06-11 | 1992-06-11 | Biphenylderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA934090B true ZA934090B (en) | 1994-12-11 |
Family
ID=6460811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA934090A ZA934090B (en) | 1992-06-11 | 1993-06-10 | Biphenyl derivatives pharmaceutical compositions containing these compounds and processes for preparing them |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0574808A1 (xx) |
| JP (1) | JPH0673038A (xx) |
| KR (1) | KR940005554A (xx) |
| CN (1) | CN1080917A (xx) |
| AU (1) | AU4120193A (xx) |
| CA (1) | CA2098158A1 (xx) |
| DE (1) | DE4219158A1 (xx) |
| FI (1) | FI932649A (xx) |
| HU (1) | HU9301700D0 (xx) |
| IL (1) | IL105976A0 (xx) |
| MX (1) | MX9303466A (xx) |
| NO (1) | NO932120L (xx) |
| PL (1) | PL299260A1 (xx) |
| ZA (1) | ZA934090B (xx) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9406144D0 (en) * | 1993-03-29 | 1994-05-18 | Zeneca Ltd | Heterocyclic compounds |
| US5753659A (en) * | 1993-03-29 | 1998-05-19 | Zeneca Limited | Heterocyclic compouds |
| US5750754A (en) * | 1993-03-29 | 1998-05-12 | Zeneca Limited | Heterocyclic compounds |
| US5652242A (en) * | 1993-03-29 | 1997-07-29 | Zeneca Limited | Heterocyclic derivatives |
| DK0691959T3 (da) * | 1993-03-29 | 1999-04-26 | Zeneca Ltd | Heterocykliske derivater som blodpladeaggregations-inhibitorer |
| GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
| GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
| US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
| DE4424974A1 (de) * | 1994-07-15 | 1996-01-18 | Thomae Gmbh Dr K | Harnstoff- und Carbaminsäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| DE19636689A1 (de) | 1996-09-10 | 1998-03-12 | Boehringer Ingelheim Kg | Neue Benzamidinderivate |
| UA52797C2 (uk) * | 1997-11-20 | 2003-01-15 | Тейдзін Лімітед | Похідне біфеніламідину, проліки, інгібітор коагуляції крові, агент для профілактики тромбозу або емболії та агент для терапії тромбозу або емболії |
| DE19819548A1 (de) * | 1998-04-30 | 1999-11-04 | Merck Patent Gmbh | Biphenylderivate |
| AU2868601A (en) * | 2000-01-27 | 2001-08-07 | Ribotargets Ltd | Biaryl compounds, their preparation and their use in therapy |
| US7534894B2 (en) | 2003-09-25 | 2009-05-19 | Wyeth | Biphenyloxy-acids |
| WO2006044975A2 (en) * | 2004-10-19 | 2006-04-27 | Compass Pharmaceuticals Llc | Compositions and their use as anti-tumor agents |
| LT3357911T (lt) | 2006-06-26 | 2022-08-10 | Akebia Therapeutics Inc. | Prolilo hidroksilazės inhibitoriai ir naudojimo būdai |
| AU2012268400C1 (en) | 2011-06-06 | 2016-12-22 | Akebia Therapeutics Inc. | Compounds and compositions for stabilizing hypoxia inducible factor-2 alpha as a method for treating cancer |
| NO2686520T3 (xx) | 2011-06-06 | 2018-03-17 | ||
| CA3151685A1 (en) | 2013-06-13 | 2014-12-18 | Akebia Therapeutics, Inc. | Compositions and methods for treating anemia |
| KR102495018B1 (ko) | 2013-11-15 | 2023-02-06 | 아케비아 테라퓨틱스 인코포레이티드 | ｛[5-(3-클로로페닐)-3-하이드록시피리딘-2-카보닐]아미노｝아세트산의 고체형, 이의 조성물 및 용도 |
| WO2016118858A1 (en) | 2015-01-23 | 2016-07-28 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
| SI3277270T1 (sl) | 2015-04-01 | 2022-04-29 | Akebia Therapeutics, Inc. | Sestavki in postopki za zdravljenje anemije |
| CA3097219A1 (en) | 2018-05-09 | 2019-11-14 | Akebia Therapeutics, Inc. | Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid |
| US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5084466A (en) * | 1989-01-31 | 1992-01-28 | Hoffmann-La Roche Inc. | Novel carboxamide pyridine compounds which have useful pharmaceutical utility |
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DE4102024A1 (de) * | 1991-01-24 | 1992-07-30 | Thomae Gmbh Dr K | Biphenylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| DK0518819T3 (da) * | 1991-06-11 | 1995-09-25 | Ciba Geigy Ag | Amidino-forbindelser, deres fremstilling og anvendelse som lægemiddel |
| DE4127404A1 (de) * | 1991-08-19 | 1993-02-25 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
-
1992
- 1992-06-11 DE DE4219158A patent/DE4219158A1/de not_active Withdrawn
-
1993
- 1993-06-08 EP EP93109190A patent/EP0574808A1/de not_active Ceased
- 1993-06-09 PL PL93299260A patent/PL299260A1/xx unknown
- 1993-06-10 NO NO932120A patent/NO932120L/no unknown
- 1993-06-10 CN CN93106962A patent/CN1080917A/zh active Pending
- 1993-06-10 ZA ZA934090A patent/ZA934090B/xx unknown
- 1993-06-10 MX MX9303466A patent/MX9303466A/es unknown
- 1993-06-10 JP JP5138438A patent/JPH0673038A/ja active Pending
- 1993-06-10 CA CA002098158A patent/CA2098158A1/en not_active Abandoned
- 1993-06-10 IL IL93105976A patent/IL105976A0/xx unknown
- 1993-06-10 KR KR1019930010494A patent/KR940005554A/ko not_active Application Discontinuation
- 1993-06-10 FI FI932649A patent/FI932649A/fi not_active Application Discontinuation
- 1993-06-10 HU HU9301700A patent/HU9301700D0/hu unknown
- 1993-06-11 AU AU41201/93A patent/AU4120193A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL105976A0 (en) | 1993-10-20 |
| CN1080917A (zh) | 1994-01-19 |
| MX9303466A (es) | 1994-01-31 |
| DE4219158A1 (de) | 1993-12-16 |
| FI932649A0 (fi) | 1993-06-10 |
| NO932120D0 (no) | 1993-06-10 |
| KR940005554A (ko) | 1994-03-21 |
| FI932649A (fi) | 1993-12-12 |
| EP0574808A1 (de) | 1993-12-22 |
| PL299260A1 (en) | 1994-03-07 |
| AU4120193A (en) | 1993-12-23 |
| CA2098158A1 (en) | 1993-12-12 |
| HU9301700D0 (en) | 1993-09-28 |
| NO932120L (no) | 1993-12-13 |
| JPH0673038A (ja) | 1994-03-15 |
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