NO931766L - Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin - Google Patents
Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfinInfo
- Publication number
- NO931766L NO931766L NO93931766A NO931766A NO931766L NO 931766 L NO931766 L NO 931766L NO 93931766 A NO93931766 A NO 93931766A NO 931766 A NO931766 A NO 931766A NO 931766 L NO931766 L NO 931766L
- Authority
- NO
- Norway
- Prior art keywords
- morphine
- transdermal delivery
- preservant
- pct
- topical preparations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9003665A SE9003665D0 (sv) | 1990-11-16 | 1990-11-16 | Morphine prodrugs |
PCT/SE1991/000760 WO1992008459A1 (en) | 1990-11-16 | 1991-11-11 | Topical compositions for transdermal delivery of produg derivatives of morphine |
Publications (2)
Publication Number | Publication Date |
---|---|
NO931766D0 NO931766D0 (no) | 1993-05-14 |
NO931766L true NO931766L (no) | 1993-05-14 |
Family
ID=20380936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO93931766A NO931766L (no) | 1990-11-16 | 1993-05-14 | Topiske preparater for transdermal avlevering av forloeperlegemiddelderivater av morfin |
Country Status (18)
Country | Link |
---|---|
US (1) | US5908846A (fi) |
EP (1) | EP0557385B1 (fi) |
JP (1) | JP3493434B2 (fi) |
AT (1) | ATE168560T1 (fi) |
AU (1) | AU655612B2 (fi) |
CA (1) | CA2095223C (fi) |
DE (1) | DE69129861T2 (fi) |
DK (1) | DK0557385T3 (fi) |
ES (1) | ES2121793T3 (fi) |
FI (1) | FI932212A0 (fi) |
IE (1) | IE913682A1 (fi) |
IL (1) | IL99905A (fi) |
NO (1) | NO931766L (fi) |
NZ (1) | NZ240349A (fi) |
PT (1) | PT99513B (fi) |
SE (1) | SE9003665D0 (fi) |
WO (1) | WO1992008459A1 (fi) |
ZA (1) | ZA918512B (fi) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5607691A (en) * | 1992-06-12 | 1997-03-04 | Affymax Technologies N.V. | Compositions and methods for enhanced drug delivery |
DE4403709A1 (de) * | 1994-02-07 | 1995-08-10 | Lohmann Therapie Syst Lts | Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid |
JPH07267862A (ja) * | 1994-03-29 | 1995-10-17 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
WO1996028451A1 (en) * | 1995-03-14 | 1996-09-19 | Euroceltique S.A. | Morphine-3-esters |
DE19508664C2 (de) * | 1995-03-14 | 2001-08-23 | Christian Mignat | Verwendung von Morphin-3-estern, Morphin-3-ester als solche und Verfahren zu deren Herstellung |
GB9519363D0 (en) | 1995-09-22 | 1995-11-22 | Euro Celtique Sa | Pharmaceutical formulation |
DE19602963A1 (de) * | 1995-12-20 | 1997-07-31 | Nycomed Arzneimittel Gmbh | Neue Morphinderivate, Verfahren zu deren Herstellung und deren Verwendung |
DE19923551A1 (de) * | 1999-05-21 | 2000-11-30 | Lohmann Therapie Syst Lts | Pharmazeutisches Präparat mit dem Wirkstoff Diamorphin und seine Verwendung in einem Verfahren zur Behandlung der Opiatsucht |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
BRPI0015284B8 (pt) | 1999-10-29 | 2021-05-25 | Euro Celtique S/A | formulações de hidrocodona de liberação controlada |
US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
KR101045144B1 (ko) | 2000-10-30 | 2011-06-30 | 유로-셀티크 소시에떼 아노뉨 | 서방성 하이드로코돈 제형 |
US6569449B1 (en) * | 2000-11-13 | 2003-05-27 | University Of Kentucky Research Foundation | Transdermal delivery of opioid antagonist prodrugs |
CN1262274C (zh) * | 2000-11-14 | 2006-07-05 | 生命健康科学有限公司 | 磷酸盐衍生物复合物 |
AUPR549901A0 (en) * | 2001-06-06 | 2001-07-12 | Vital Health Sciences Pty Ltd | Topical formulation containing tocopheryl phosphates |
US20110104214A1 (en) | 2004-04-15 | 2011-05-05 | Purdue Pharma L.P. | Once-a-day oxycodone formulations |
US20030022876A1 (en) * | 2001-06-05 | 2003-01-30 | Ashton Paul A. | Sustained-release analgesic compounds |
MXPA04000654A (es) * | 2001-07-27 | 2004-03-19 | Vital Health Sciences Pty Ltd | Terapia dermica usando derivados de fosfato de agente de transferencia de electrones. |
CA2466536C (en) * | 2001-12-13 | 2012-02-07 | Vital Health Sciences Pty Ltd | Transdermal transport of compounds |
AU2002950713A0 (en) | 2002-08-09 | 2002-09-12 | Vital Health Sciences Pty Ltd | Carrier |
DE60329515D1 (de) * | 2002-10-25 | 2009-11-12 | Euro Celtique Sa | Analoga und prodrugs von buprenorphin |
WO2004043396A2 (en) * | 2002-11-09 | 2004-05-27 | Nobex Corporation | Modified carbamate-containing prodrugs and methods of synthesizing same |
ATE534384T1 (de) * | 2003-01-17 | 2011-12-15 | Vital Health Sciences Pty Ltd | Verbindungen mit proliferationshemmenden eigenschaften |
AU2003901815A0 (en) * | 2003-04-15 | 2003-05-01 | Vital Health Sciences Pty Ltd | Phosphate derivatives |
CA2529983C (en) * | 2003-07-25 | 2010-07-20 | Bruce E. Reidenberg | Preoperative treatment of post operative pain |
ES2338054T3 (es) | 2004-02-06 | 2010-05-03 | Euro-Celtique S.A. | Metodos para producir morfinonas 3-o-protegidas y carboxilatos de morfinona dienol 3-o-protegidos. |
ES2447547T3 (es) | 2004-02-23 | 2014-03-12 | Euro-Celtique S.A. | Dispositivo de administración transdérmica de opioides con resistencia al abuso |
DE602005025979D1 (de) | 2004-03-03 | 2011-03-03 | Vital Health Sciences Pty Ltd | Alkaloid-formulierungen |
EP1893159B1 (en) | 2005-06-17 | 2015-09-30 | Vital Health Sciences Pty Ltd. | A carrier comprising one or more di- and/or monophosphate derivatives of electron transfer agents |
KR20080085839A (ko) * | 2005-12-23 | 2008-09-24 | 바이탈 헬스 사이언시즈 피티와이 리미티드 | 사이토킨 조절 특성을 가진 화합물 |
JP5313868B2 (ja) | 2007-03-02 | 2013-10-09 | テイカ製薬株式会社 | 経皮吸収医薬組成物、医薬組成物貯蔵ユニットおよびこれを利用する経皮吸収製剤 |
US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
US8354116B2 (en) * | 2007-06-18 | 2013-01-15 | Biochemics, Inc. | Bifunctional synthetic molecules |
US8784872B2 (en) | 2007-11-19 | 2014-07-22 | Comgenrx, Inc. | Formulation for decreasing tobacco, alcohol, drug or food consumption |
US20090130048A1 (en) * | 2007-11-19 | 2009-05-21 | Oronsky Bryan Todd | Topical Composition for Treating Pain |
WO2009158667A2 (en) * | 2008-06-27 | 2009-12-30 | Comgenrx, Inc. | Povidone compositions for wound healing |
US10849981B2 (en) | 2009-07-02 | 2020-12-01 | KemPham, Inc. | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof |
UA102916C2 (uk) * | 2009-07-02 | 2013-08-27 | Кемфарм, Інк. | Композиція на основі кон'югату гідрокодону з бензойною кислотою, похідними бензойної кислоти або гетероарилкарбоновою кислотою, проліки, спосіб лікування від зловживань |
AU2010266209B2 (en) * | 2009-07-02 | 2013-09-26 | Kempharm, Inc. | Phenylethanoic acid, phenylpropanoic acid and phenylpropenoic acid conjugates and prodrugs of hydrocodone, methods of making and use thereof |
WO2011094814A1 (en) | 2010-02-05 | 2011-08-11 | Phosphagenics Limited | Carrier comprising non-neutralised tocopheryl phosphate |
MX2012011355A (es) | 2010-03-30 | 2012-11-30 | Phosphagenics Ltd | Parche de suministro transdermico. |
KR101955175B1 (ko) | 2010-04-13 | 2019-03-06 | 나지브 바불 | 1-메틸-2'-6'-피페콜옥실리디드의 피부 약제학적 조성물 및 사용 방법 |
TWI590821B (zh) | 2011-01-18 | 2017-07-11 | 輝瑞有限公司 | 固體分子分散液 |
US9561243B2 (en) | 2011-03-15 | 2017-02-07 | Phosphagenics Limited | Composition comprising non-neutralised tocol phosphate and a vitamin A compound |
EP3223819A4 (en) | 2014-11-25 | 2018-04-25 | Kempharm, Inc. | Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of oxycodone |
AU2016367708B2 (en) | 2015-12-09 | 2022-07-14 | Phosphagenics Limited | Pharmaceutical formulation |
KR102647670B1 (ko) | 2016-12-21 | 2024-03-15 | 아베초 바이오테크놀로지 리미티드 | 방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
US4673679A (en) * | 1986-05-14 | 1987-06-16 | E. I. Du Pont De Nemours And Company | Use of prodrugs of 3-hydroxymorphinans to prevent bitter taste upon buccal, nasal or sublingual administration |
US4908389A (en) * | 1986-08-27 | 1990-03-13 | Warner-Lambert Company | Penetration enhancement system |
US4940586A (en) * | 1987-02-26 | 1990-07-10 | Alza Corporation | Skin permeation enhancer compositions using sucrose esters |
US4879297A (en) * | 1987-06-01 | 1989-11-07 | Warner-Lambert Company | Fatty acids and their small chain esters as penetration enhancers in aqueous systems |
US4891377A (en) * | 1988-12-02 | 1990-01-02 | Board Of Regents Acting For And On Behalf Of University Of Michigan | Transdermal delivery of the narcotic analgesics etorphine and analogs |
WO1991015241A1 (en) * | 1990-03-30 | 1991-10-17 | Yasunori Morimoto | Percutaneously absorbable composition of narcotic and nonnarcotic analgesics |
US5069909A (en) * | 1990-06-20 | 1991-12-03 | Cygnus Therapeutic Systems | Transdermal administration of buprenorphine |
-
1990
- 1990-11-16 SE SE9003665A patent/SE9003665D0/xx unknown
-
1991
- 1991-10-21 IE IE368291A patent/IE913682A1/en not_active IP Right Cessation
- 1991-10-25 NZ NZ240349A patent/NZ240349A/en not_active IP Right Cessation
- 1991-10-25 ZA ZA918512A patent/ZA918512B/xx unknown
- 1991-10-30 IL IL9990591A patent/IL99905A/en not_active IP Right Cessation
- 1991-11-11 CA CA002095223A patent/CA2095223C/en not_active Expired - Fee Related
- 1991-11-11 WO PCT/SE1991/000760 patent/WO1992008459A1/en active IP Right Grant
- 1991-11-11 US US08/050,336 patent/US5908846A/en not_active Expired - Fee Related
- 1991-11-11 JP JP50056892A patent/JP3493434B2/ja not_active Expired - Fee Related
- 1991-11-11 ES ES91920399T patent/ES2121793T3/es not_active Expired - Lifetime
- 1991-11-11 DK DK91920399T patent/DK0557385T3/da active
- 1991-11-11 EP EP91920399A patent/EP0557385B1/en not_active Expired - Lifetime
- 1991-11-11 AU AU89381/91A patent/AU655612B2/en not_active Ceased
- 1991-11-11 DE DE69129861T patent/DE69129861T2/de not_active Expired - Fee Related
- 1991-11-11 AT AT91920399T patent/ATE168560T1/de not_active IP Right Cessation
- 1991-11-14 PT PT99513A patent/PT99513B/pt not_active IP Right Cessation
-
1993
- 1993-05-14 NO NO93931766A patent/NO931766L/no unknown
- 1993-05-14 FI FI932212A patent/FI932212A0/fi unknown
Also Published As
Publication number | Publication date |
---|---|
DE69129861D1 (de) | 1998-08-27 |
WO1992008459A1 (en) | 1992-05-29 |
ZA918512B (en) | 1992-08-26 |
JP3493434B2 (ja) | 2004-02-03 |
NO931766D0 (no) | 1993-05-14 |
IE913682A1 (en) | 1992-05-20 |
AU655612B2 (en) | 1995-01-05 |
SE9003665D0 (sv) | 1990-11-16 |
CA2095223A1 (en) | 1992-05-17 |
US5908846A (en) | 1999-06-01 |
IL99905A (en) | 1995-06-29 |
DE69129861T2 (de) | 1999-04-01 |
DK0557385T3 (da) | 1999-04-26 |
CA2095223C (en) | 2002-12-17 |
EP0557385A1 (en) | 1993-09-01 |
JPH06502422A (ja) | 1994-03-17 |
IL99905A0 (en) | 1992-08-18 |
FI932212A (fi) | 1993-05-14 |
PT99513A (pt) | 1992-09-30 |
NZ240349A (en) | 1993-07-27 |
PT99513B (pt) | 1999-04-30 |
ATE168560T1 (de) | 1998-08-15 |
ES2121793T3 (es) | 1998-12-16 |
EP0557385B1 (en) | 1998-07-22 |
AU8938191A (en) | 1992-06-11 |
FI932212A0 (fi) | 1993-05-14 |
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