NO931225L - Benzoksazinon- og benzotiazinon-derivater med kardiovaskulaer akrivitet - Google Patents
Benzoksazinon- og benzotiazinon-derivater med kardiovaskulaer akrivitetInfo
- Publication number
- NO931225L NO931225L NO93931225A NO931225A NO931225L NO 931225 L NO931225 L NO 931225L NO 93931225 A NO93931225 A NO 93931225A NO 931225 A NO931225 A NO 931225A NO 931225 L NO931225 L NO 931225L
- Authority
- NO
- Norway
- Prior art keywords
- benzotiazinon
- benzoksazinon
- acrivity
- cardiovascular
- derivatives
- Prior art date
Links
- 230000002526 effect on cardiovascular system Effects 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- -1 methylenedioxy Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 1
- YBYIZRPBXCCDQW-UHFFFAOYSA-N 2,3-dihydro-1,3-benzoxazin-4-one Chemical class C1=CC=C2C(=O)NCOC2=C1 YBYIZRPBXCCDQW-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
- C07D265/22—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/08—1,3-Thiazines; Hydrogenated 1,3-thiazines condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Control Of Transmission Device (AREA)
- Optical Filters (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI920940A IT1254884B (it) | 1992-04-16 | 1992-04-16 | Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO931225D0 NO931225D0 (no) | 1993-03-31 |
| NO931225L true NO931225L (no) | 1993-10-18 |
Family
ID=11362985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO93931225A NO931225L (no) | 1992-04-16 | 1993-03-31 | Benzoksazinon- og benzotiazinon-derivater med kardiovaskulaer akrivitet |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5480882A (de) |
| EP (1) | EP0566018B1 (de) |
| JP (1) | JP3257716B2 (de) |
| CN (1) | CN1078466A (de) |
| AT (1) | ATE169293T1 (de) |
| AU (1) | AU655540B2 (de) |
| CA (1) | CA2092342A1 (de) |
| DE (1) | DE69320087T2 (de) |
| FI (1) | FI931688A (de) |
| HU (1) | HUT68605A (de) |
| IL (1) | IL105158A (de) |
| IT (1) | IT1254884B (de) |
| MX (1) | MX9302165A (de) |
| NO (1) | NO931225L (de) |
| NZ (1) | NZ247249A (de) |
| TW (1) | TW288013B (de) |
| ZA (1) | ZA932030B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1264812B1 (it) * | 1993-07-28 | 1996-10-10 | Italfarmaco Spa | Derivati benzossazinonici e benzotiazinonici terapeuticamente attivi |
| WO2001004103A1 (en) * | 1999-07-13 | 2001-01-18 | F. Hoffmann-La Roche Ag | Benzazepinones and quinazolines |
| CA2419838A1 (en) | 2000-08-31 | 2003-02-18 | Takeda Chemical Industries, Ltd. | Heart muscular cell apoptosis inhibitors and remedies/preventives for heart diseases |
| JP5700547B2 (ja) | 2011-05-30 | 2015-04-15 | 国立大学法人京都大学 | バイオチップ形成用感光性樹脂組成物、及びバイオチップ |
| CN102367239B (zh) * | 2011-07-20 | 2015-10-28 | 沈阳药科大学 | 2-芳基-2,3-二氢-4h-1,3-苯并噻嗪-4-酮衍生物及其用途 |
| CN103012188A (zh) * | 2011-09-20 | 2013-04-03 | 北京京卫信康医药科技发展有限公司 | 一种龙胆酸乙醇胺的制备方法 |
| CN102631108A (zh) * | 2012-04-25 | 2012-08-15 | 张家港市立达金属制品有限公司 | 帽子展示架 |
| ITMI20122221A1 (it) * | 2012-12-21 | 2014-06-22 | C4T S C A R L | Nuovi composti del 2,3-diidro-4h-1,3-benzossazin-4-one, metodo per prepararli e forma farmaceutica che li comprende |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539563A (en) * | 1965-09-27 | 1970-11-10 | Istituto Chemioterapico | Tetracycline: 6-amino-4-oxo-2-(beta-chloroethyl) - 2,3 - dihydrobenzene - 1,3-oxazine double salt dihydrate |
| US3459748A (en) * | 1967-04-28 | 1969-08-05 | Squibb & Sons Inc | Hydroxyalkylene-substituted benzoxazines and benzothiazines |
| FR2636065B1 (fr) * | 1988-09-08 | 1993-05-07 | Fabre Sa Pierre | Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique |
| IT1244472B (it) * | 1990-12-14 | 1994-07-15 | Italfarmaco Spa | Benzossazinoni e benzotiazinoni ad attivita' cardiovascolare |
-
1992
- 1992-04-16 IT ITMI920940A patent/IT1254884B/it active IP Right Grant
-
1993
- 1993-03-22 ZA ZA932030A patent/ZA932030B/xx unknown
- 1993-03-24 IL IL10515893A patent/IL105158A/en not_active IP Right Cessation
- 1993-03-24 CA CA002092342A patent/CA2092342A1/en not_active Abandoned
- 1993-03-25 NZ NZ247249A patent/NZ247249A/xx unknown
- 1993-03-30 AU AU35617/93A patent/AU655540B2/en not_active Ceased
- 1993-03-31 NO NO93931225A patent/NO931225L/no unknown
- 1993-04-07 DE DE69320087T patent/DE69320087T2/de not_active Expired - Fee Related
- 1993-04-07 EP EP93105752A patent/EP0566018B1/de not_active Expired - Lifetime
- 1993-04-07 AT AT93105752T patent/ATE169293T1/de active
- 1993-04-14 FI FI931688A patent/FI931688A/fi not_active Application Discontinuation
- 1993-04-14 TW TW082102853A patent/TW288013B/zh active
- 1993-04-14 MX MX9302165A patent/MX9302165A/es unknown
- 1993-04-15 JP JP11214993A patent/JP3257716B2/ja not_active Expired - Fee Related
- 1993-04-15 HU HU9301106A patent/HUT68605A/hu unknown
- 1993-04-16 CN CN 93104624 patent/CN1078466A/zh active Pending
-
1994
- 1994-11-23 US US08/347,217 patent/US5480882A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP3257716B2 (ja) | 2002-02-18 |
| EP0566018B1 (de) | 1998-08-05 |
| FI931688A0 (fi) | 1993-04-14 |
| AU655540B2 (en) | 1994-12-22 |
| EP0566018A3 (en) | 1994-06-01 |
| ITMI920940A0 (it) | 1992-04-16 |
| DE69320087D1 (de) | 1998-09-10 |
| ATE169293T1 (de) | 1998-08-15 |
| HUT68605A (en) | 1995-06-28 |
| DE69320087T2 (de) | 1998-12-10 |
| MX9302165A (es) | 1993-10-01 |
| IL105158A (en) | 1996-10-31 |
| ZA932030B (en) | 1993-10-19 |
| FI931688A (fi) | 1993-10-17 |
| HU9301106D0 (en) | 1993-07-28 |
| NO931225D0 (no) | 1993-03-31 |
| ITMI920940A1 (it) | 1993-10-16 |
| EP0566018A2 (de) | 1993-10-20 |
| AU3561793A (en) | 1993-10-21 |
| TW288013B (de) | 1996-10-11 |
| US5480882A (en) | 1996-01-02 |
| NZ247249A (en) | 1995-01-27 |
| JPH0625194A (ja) | 1994-02-01 |
| CA2092342A1 (en) | 1993-10-17 |
| CN1078466A (zh) | 1993-11-17 |
| IT1254884B (it) | 1995-10-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3588100D1 (de) | Carbamidsäureester-Derivate, Mittel und Herstellungsverfahren | |
| AU5898580A (en) | Pyroglutamic acid derivatives | |
| DK345989A (da) | Quinolinderivater | |
| NO942452L (no) | Amid- og ureaderivater med antihyperkolesteremisk aktivitet, deres fremstilling og terapeutiske anvendelser | |
| FI862757A (fi) | Pyridonkarbonsyraderivat och foerfarande foer framstaellning av dessa. | |
| LU91031I2 (en) | Zaxem | |
| NO931225L (no) | Benzoksazinon- og benzotiazinon-derivater med kardiovaskulaer akrivitet | |
| IS3828A (is) | Hliðstæð aðferð til tilreiðslu á nýjum afleiðum thiazolidinone og oxazolidinone sem gagnlegar eru til æðaútvíkkunar | |
| NO895198D0 (no) | Fremgangsmaate for fremstilling av 4,5,6,7-tetrahydrobenzimidazolderivater. | |
| DK0417790T3 (da) | S-triazolo(3,4-i)purin-derivater | |
| DE3561153D1 (de) | Benzoylurea derivatives | |
| IT1241988B (it) | 2- amminotetraline-6, 7-sostituite attive come immunomodulanti e composizioni farmaceutiche che le contengono | |
| ES8603806A1 (es) | Procedimiento para preparar nuevas n-(naftilalquil)-hidroxi-laminas | |
| ES2055094T3 (es) | Utilizacion de poliaminas oxidadas, en particular nn'-bis-(3-propionaldehido)-1-4-diaminobutano (dialdehido espermina) como agentes inmunosupresores. | |
| FI955680A0 (fi) | Psoraleenijohdannaiset, niiden valmistus ja käyttö | |
| ES2039270T3 (es) | Derivados de gamma-l-glutamil-4-nitroanilida y procedimiento para determinar actividad de gamma-gtp utilizandolos. | |
| ES8707500A1 (es) | Procedimiento para la obtencion de isocianatos piperidinicos. | |
| GEP19970664B (en) | Acrylic acid derivatives and stereoisomers | |
| FI851565A0 (fi) | Blodtryckssaenkande 1,2 -benzisotiazolpiperidiner, foerfarande foer deras syntetisering och deras anvaendning saosom laekemedel. |