ES8603806A1 - Procedimiento para preparar nuevas n-(naftilalquil)-hidroxi-laminas - Google Patents

Procedimiento para preparar nuevas n-(naftilalquil)-hidroxi-laminas

Info

Publication number
ES8603806A1
ES8603806A1 ES539501A ES539501A ES8603806A1 ES 8603806 A1 ES8603806 A1 ES 8603806A1 ES 539501 A ES539501 A ES 539501A ES 539501 A ES539501 A ES 539501A ES 8603806 A1 ES8603806 A1 ES 8603806A1
Authority
ES
Spain
Prior art keywords
hydroxylamines
naphthyl
alkyl
hydrogen
naphthalinalkanamines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES539501A
Other languages
English (en)
Other versions
ES539501A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848400964A external-priority patent/GB8400964D0/en
Priority claimed from GB848412684A external-priority patent/GB8412684D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8603806A1 publication Critical patent/ES8603806A1/es
Publication of ES539501A0 publication Critical patent/ES539501A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVAS -(NAFTILALQUIL)-HIDROXILAMINAS. CONSISTE EN HACER REACCIONAR UN (5-,6-,7- U 8-ALCOXI)-1- O -2-NAFTALINALCANO, DE FORMULA (II), CON HIDROXILAMINA O UNA HIDROXILAMINA N-MONOSUSTITUIDA DE FORMULA (III), EN PRESENCIA DE UN DISOLVENTE O DILUYENTE INERTE, A UNA TEMPERATURA ENTRE 0 Y 100JC, PARA OBTENER UNA N-HIDROXI-(5,6,7 U 8-ALCOXI) -1- O -2-NAFTALINALCANAMINA DE FORMULA (I), O UN ESTER DE LA MISMA FISIOLOGICAMENTE HIDROLIZABLE, BAJO LA FORMA DE BASE LIBRE O DE SAL DE ADICION DE ACIDOS. SIENDO: A, GRUPO ALQUILENO DE C 1 A 6; R1, H, GRUPO ALQUILO DE C 1 A 8 O UN GRUPO CICLOALQUILO DE C 4 A 6; R2, GRUPO ALQUILO DE C 1 A 6; R3 , H O HAL; Y Z, GRUPO SUSCEPTIBLE DE SER ELIMINADO.SE UTILIZA EN EL TRATAMIENTO DE LEUCOTRIEAS, PARA EL TRATAMIENTO O LA PROFILACTICA DEL ASMA, DE LA INFAMACION Y DE LA PSONASIS.
ES539501A 1984-01-13 1985-01-11 Procedimiento para preparar nuevas n-(naftilalquil)-hidroxi-laminas Granted ES539501A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848400964A GB8400964D0 (en) 1984-01-13 1984-01-13 Organic compounds
GB848412684A GB8412684D0 (en) 1984-05-18 1984-05-18 Organic compounds

Publications (2)

Publication Number Publication Date
ES8603806A1 true ES8603806A1 (es) 1986-01-01
ES539501A0 ES539501A0 (es) 1986-01-01

Family

ID=26287189

Family Applications (1)

Application Number Title Priority Date Filing Date
ES539501A Granted ES539501A0 (es) 1984-01-13 1985-01-11 Procedimiento para preparar nuevas n-(naftilalquil)-hidroxi-laminas

Country Status (11)

Country Link
EP (1) EP0149588A3 (es)
AU (1) AU576211B2 (es)
DK (1) DK14485A (es)
ES (1) ES539501A0 (es)
FI (1) FI850131L (es)
GR (1) GR850081B (es)
HU (1) HUT37741A (es)
IL (1) IL74042A0 (es)
NZ (1) NZ210817A (es)
PH (1) PH21512A (es)
PT (1) PT79823B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5026759A (en) * 1985-05-08 1991-06-25 Du Pont Merck Pharmaceutical 2-substituted-1-naphthols as 5-lipoxygenase inhibitors
US4833164A (en) * 1985-05-08 1989-05-23 E. I. Du Pont De Nemours And Company 2-substituted-1-naphthols, pharmaceutical compositions of, and their use as 5-lipoxygenase inhibitors
SU1600627A3 (ru) * 1985-05-08 1990-10-15 Е.И.Дюпон Де Немур Энд Компани (Фирма) Способ получени 2-замещенных 1-нафтолов
DE3739882A1 (de) * 1987-11-25 1989-06-08 Bayer Ag Substituierte hydroxylamine
CA2024971A1 (en) * 1989-09-14 1991-03-15 Atsuo Hazato Naphthalene derivative and preparation method thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1400503A3 (ru) * 1983-05-18 1988-05-30 Циба-Гейги Аг (Фирма) Способ получени производных циклогександионкарбоновой кислоты
AU571240B2 (en) * 1983-07-11 1988-04-14 Commonwealth Scientific And Industrial Research Organisation Alkoxy-amines, useful as initiators

Also Published As

Publication number Publication date
NZ210817A (en) 1988-08-30
DK14485D0 (da) 1985-01-11
FI850131A0 (fi) 1985-01-11
AU576211B2 (en) 1988-08-18
DK14485A (da) 1985-07-14
IL74042A0 (en) 1985-04-30
GR850081B (es) 1985-05-03
EP0149588A3 (en) 1986-05-07
ES539501A0 (es) 1986-01-01
HUT37741A (en) 1986-02-28
PT79823B (en) 1987-01-07
AU3761085A (en) 1985-07-18
PT79823A (en) 1985-02-01
PH21512A (en) 1987-11-10
FI850131L (fi) 1985-07-14
EP0149588A2 (en) 1985-07-24

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