DK345989A - Quinolinderivater - Google Patents
Quinolinderivater Download PDFInfo
- Publication number
- DK345989A DK345989A DK345989A DK345989A DK345989A DK 345989 A DK345989 A DK 345989A DK 345989 A DK345989 A DK 345989A DK 345989 A DK345989 A DK 345989A DK 345989 A DK345989 A DK 345989A
- Authority
- DK
- Denmark
- Prior art keywords
- quinoline
- acyltransferase
- coa
- cholesterol
- aralkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
- C07D215/60—N-oxides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17413788 | 1988-07-12 | ||
JP21426688 | 1988-08-29 | ||
JP7592589 | 1989-03-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK345989D0 DK345989D0 (da) | 1989-07-12 |
DK345989A true DK345989A (da) | 1990-01-13 |
Family
ID=27301993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK345989A DK345989A (da) | 1988-07-12 | 1989-07-12 | Quinolinderivater |
Country Status (17)
Country | Link |
---|---|
US (1) | US5254565A (da) |
EP (1) | EP0354994B1 (da) |
KR (1) | KR900001656A (da) |
AT (1) | ATE117681T1 (da) |
AU (1) | AU616542B2 (da) |
CA (1) | CA1333068C (da) |
DE (1) | DE68920796T2 (da) |
DK (1) | DK345989A (da) |
ES (1) | ES2066808T3 (da) |
FI (1) | FI93353C (da) |
GR (1) | GR3015554T3 (da) |
HU (1) | HU210861B (da) |
IE (1) | IE892088L (da) |
IL (1) | IL90815A (da) |
NO (1) | NO177300C (da) |
NZ (1) | NZ229911A (da) |
PT (1) | PT91121B (da) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW205037B (da) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
JPH03181465A (ja) * | 1989-12-11 | 1991-08-07 | Takeda Chem Ind Ltd | キノリン誘導体 |
DE4014171A1 (de) * | 1990-05-03 | 1991-11-07 | Basf Ag | Cyanochinolinverbindungen |
US5143919A (en) * | 1990-08-17 | 1992-09-01 | Takeda Chemical Industries, Ltd. | Thienopyridine derivatives and their pharmaceutical use |
US5256782A (en) * | 1990-08-17 | 1993-10-26 | Takeda Chemical Industries, Ltd. | Thienopyridine derivatives which are intermediates |
US5668136A (en) * | 1990-09-25 | 1997-09-16 | Eisai Co., Ltd. | Trisubstituted benzene derivatives, composition and methods of treatment |
JPH059179A (ja) * | 1990-09-27 | 1993-01-19 | Takeda Chem Ind Ltd | 複素環化合物、その製造法及びacat阻害剤 |
BR9205939A (pt) * | 1991-04-26 | 1994-09-27 | Pfizer | Derivados de 4-aril-3-(heteroalilureído)quinolina |
IL101785A0 (en) * | 1991-05-10 | 1992-12-30 | Fujisawa Pharmaceutical Co | Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
ES2125325T3 (es) * | 1992-01-23 | 1999-03-01 | Pfizer | Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos. |
US5310748A (en) * | 1992-05-11 | 1994-05-10 | The Du Pont Merck Pharmaceutical Company | Imidazoles for the treatment of atherosclerosis |
US5364875A (en) * | 1992-05-11 | 1994-11-15 | The Du Pont Merck Pharmaceutical Company | Imidazoles linked to bicyclic heterocyclic groups for the treatment of atherosclerosis |
EP0609457B1 (en) * | 1992-07-20 | 1997-10-29 | Eisai Co., Ltd. | Benzene derivative |
US5482967A (en) * | 1992-09-04 | 1996-01-09 | Takeda Chemical Industries, Ltd. | Condensed heterocyclic compounds, their production and use |
US5565472A (en) * | 1992-12-21 | 1996-10-15 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
GB9302275D0 (en) * | 1993-02-05 | 1993-03-24 | Smithkline Beecham Plc | Novel compounds |
NZ264063A (en) * | 1993-08-13 | 1995-11-27 | Nihon Nohyaku Co Ltd | N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions |
US5596001A (en) * | 1993-10-25 | 1997-01-21 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)quinoline derivatves |
TW263498B (da) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
US5491152A (en) * | 1994-03-23 | 1996-02-13 | The Du Pont Merck Pharmaceutical Company | Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis |
JP3720395B2 (ja) * | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
NZ308228A (en) * | 1995-05-31 | 1999-11-29 | Sumitomo Pharma | Substituted 1,8-naphthyridine derivatives |
DE69617731T2 (de) | 1995-10-05 | 2002-08-08 | Kyoto Pharmaceutical Industries, Ltd. | Neue heterozyklische derivate und ihre medizinische anwendung |
CA2190708A1 (en) * | 1995-12-08 | 1997-06-09 | Johannes Aebi | Aminoalkyl substituted benzo-heterocyclic compounds |
DE19627430A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Bicyclisch kondensierte Pyridine |
EP1541553B1 (en) * | 2002-07-17 | 2010-06-02 | Kyoto Pharmaceutical Industries, Ltd. | Indoline compound and medicinal use thereof |
US7977354B2 (en) | 2005-04-01 | 2011-07-12 | Insa Rouen | Heterocyclic compounds, their preparation and their use as medicaments, in particular as anti-alzheimer agents |
US20160332971A1 (en) * | 2015-05-15 | 2016-11-17 | University Of Kentucky Research Foundation | Arylquinoline, arylquinolone and arylthioquinolone derivatives and use thereof to treat cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO133758C (da) * | 1970-04-04 | 1976-06-23 | Takeda Chemical Industries Ltd | |
US3819634A (en) * | 1970-07-23 | 1974-06-25 | Takeda Chemical Industries Ltd | 4-phenyl-3-thioacrylaminoquinolines |
JPS555502B1 (da) * | 1971-07-31 | 1980-02-07 |
-
1989
- 1989-06-27 IE IE892088A patent/IE892088L/xx unknown
- 1989-06-30 IL IL90815A patent/IL90815A/xx not_active IP Right Cessation
- 1989-07-10 NO NO892851A patent/NO177300C/no unknown
- 1989-07-11 AU AU38025/89A patent/AU616542B2/en not_active Ceased
- 1989-07-11 DE DE68920796T patent/DE68920796T2/de not_active Expired - Fee Related
- 1989-07-11 AT AT89112683T patent/ATE117681T1/de active
- 1989-07-11 EP EP89112683A patent/EP0354994B1/en not_active Expired - Lifetime
- 1989-07-11 CA CA000605291A patent/CA1333068C/en not_active Expired - Fee Related
- 1989-07-11 ES ES89112683T patent/ES2066808T3/es not_active Expired - Lifetime
- 1989-07-11 PT PT91121A patent/PT91121B/pt not_active IP Right Cessation
- 1989-07-11 HU HU893485A patent/HU210861B/hu not_active IP Right Cessation
- 1989-07-11 FI FI893361A patent/FI93353C/fi not_active IP Right Cessation
- 1989-07-11 NZ NZ229911A patent/NZ229911A/en unknown
- 1989-07-12 KR KR1019890009937A patent/KR900001656A/ko active IP Right Grant
- 1989-07-12 DK DK345989A patent/DK345989A/da not_active Application Discontinuation
-
1991
- 1991-12-16 US US07/807,813 patent/US5254565A/en not_active Expired - Fee Related
-
1995
- 1995-03-28 GR GR950400730T patent/GR3015554T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI893361A (fi) | 1990-01-13 |
DK345989D0 (da) | 1989-07-12 |
FI893361A0 (fi) | 1989-07-11 |
FI93353B (fi) | 1994-12-15 |
DE68920796D1 (de) | 1995-03-09 |
EP0354994A3 (en) | 1991-05-15 |
GR3015554T3 (en) | 1995-06-30 |
HUT52059A (en) | 1990-06-28 |
NO892851D0 (no) | 1989-07-10 |
KR900001656A (ko) | 1990-02-27 |
CA1333068C (en) | 1994-11-15 |
US5254565A (en) | 1993-10-19 |
NO177300C (no) | 1995-08-23 |
NZ229911A (en) | 1991-08-27 |
IE892088L (en) | 1990-01-12 |
FI93353C (fi) | 1995-03-27 |
HU210861B (en) | 1995-08-28 |
PT91121B (pt) | 1995-01-31 |
NO892851L (no) | 1990-01-15 |
IL90815A0 (en) | 1990-01-18 |
IL90815A (en) | 1993-07-08 |
NO177300B (no) | 1995-05-15 |
ES2066808T3 (es) | 1995-03-16 |
EP0354994B1 (en) | 1995-01-25 |
EP0354994A2 (en) | 1990-02-21 |
AU3802589A (en) | 1990-01-18 |
AU616542B2 (en) | 1991-10-31 |
ATE117681T1 (de) | 1995-02-15 |
PT91121A (pt) | 1990-02-08 |
DE68920796T2 (de) | 1995-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |