NO931141L - Tnf-muteiner - Google Patents

Tnf-muteiner

Info

Publication number
NO931141L
NO931141L NO93931141A NO931141A NO931141L NO 931141 L NO931141 L NO 931141L NO 93931141 A NO93931141 A NO 93931141A NO 931141 A NO931141 A NO 931141A NO 931141 L NO931141 L NO 931141L
Authority
NO
Norway
Prior art keywords
mutein
necrosis factor
tumor necrosis
vector
human
Prior art date
Application number
NO93931141A
Other languages
English (en)
Norwegian (no)
Other versions
NO931141D0 (no
Inventor
Werner Lesslauer
Hansruedi Loetscher
Dietrich Stueber
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO931141D0 publication Critical patent/NO931141D0/no
Publication of NO931141L publication Critical patent/NO931141L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/525Tumour necrosis factor [TNF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO93931141A 1992-04-02 1993-03-26 Tnf-muteiner NO931141L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92810249 1992-04-02

Publications (2)

Publication Number Publication Date
NO931141D0 NO931141D0 (no) 1993-03-26
NO931141L true NO931141L (no) 1993-10-04

Family

ID=8211902

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93931141A NO931141L (no) 1992-04-02 1993-03-26 Tnf-muteiner

Country Status (19)

Country Link
US (1) US5486463A (cs)
EP (1) EP0563714A3 (cs)
JP (1) JPH07285997A (cs)
CN (1) CN1037844C (cs)
AU (1) AU659927B2 (cs)
BR (1) BR9301420A (cs)
CA (1) CA2091313A1 (cs)
CZ (1) CZ283533B6 (cs)
FI (1) FI931488A7 (cs)
HU (1) HUT69790A (cs)
IL (1) IL105170A0 (cs)
MX (1) MX9301700A (cs)
NO (1) NO931141L (cs)
NZ (1) NZ247265A (cs)
PL (1) PL298345A1 (cs)
SK (1) SK376492A3 (cs)
TW (1) TW260707B (cs)
UY (1) UY23561A1 (cs)
ZA (1) ZA932177B (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970005042B1 (ko) * 1993-02-09 1997-04-11 한일합성섬유공업 주식회사 종양괴사인자-알파 뮤테인
CA2119089A1 (en) * 1993-03-29 1994-09-30 David Banner Tumor necrosis factor muteins
CN1049663C (zh) * 1994-09-01 2000-02-23 中国科学院上海生物工程研究中心 突变的人肿瘤坏死因子
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
US20020077276A1 (en) * 1999-04-27 2002-06-20 Fredeking Terry M. Compositions and methods for treating hemorrhagic virus infections and other disorders
US6379708B1 (en) * 1999-11-20 2002-04-30 Cytologic, Llc Method for enhancing immune responses in mammals
ATE511857T1 (de) * 2000-02-16 2011-06-15 Genentech Inc Anti-april monoklonaler antikörper und deren verwendung zur behandlung von immunerkrankungen oder krebs
EP1572881A4 (en) * 2001-08-03 2007-06-13 Genentech Inc TACI AND BR3 POLYPEPTIDES AND USES THEREOF
US7786282B2 (en) * 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
US20030199024A1 (en) * 2002-04-19 2003-10-23 Hansen Ted H. Single chain trimers of class I MHC molecules
CN1692127A (zh) * 2002-07-25 2005-11-02 健泰科生物技术公司 Taci抗体及其用途
EP1578799B8 (en) * 2002-12-02 2011-03-23 Amgen Fremont Inc. Antibodies directed to tumor necrosis factor and uses thereof
US20040121971A1 (en) * 2002-12-20 2004-06-24 Gang Chen Therapeutic use of tumor necrosis factor-alpha mutein
US20050163775A1 (en) * 2003-06-05 2005-07-28 Genentech, Inc. Combination therapy for B cell disorders
AU2004256042A1 (en) * 2003-06-05 2005-01-20 Genentech, Inc. BlyS antagonists and uses thereof
CN100390200C (zh) * 2003-11-24 2008-05-28 中国医学科学院基础医学研究所 一种用于治疗获得性免疫缺陷综合征的重组靶向融合蛋白
TW201122103A (en) * 2004-01-06 2011-07-01 Hayashibara Biochem Lab Tnf antagonists and tnf inhibitors comprising the same as the active ingredient
CN1752211B (zh) * 2004-09-23 2010-09-15 中国医学科学院基础医学研究所 用于治疗获得性免疫缺陷综合征的重组靶向融合蛋白
GB0425972D0 (en) 2004-11-25 2004-12-29 Celltech R&D Ltd Biological products
US7850960B2 (en) 2004-12-30 2010-12-14 University Of Washington Methods for regulation of stem cells
US20070065514A1 (en) * 2005-09-22 2007-03-22 Howell Mark D Method for enhancing immune responses in mammals
US9726673B2 (en) * 2005-11-23 2017-08-08 Genentech, Inc. Methods and compositions related to B cell assays
US8518697B2 (en) * 2006-04-04 2013-08-27 Washington University Single chain trimers and uses therefor
US20100316626A1 (en) * 2006-08-11 2010-12-16 The Government Of The United States Of America As Represented By The Secretary Methods for treatment and diagnosis of psychiatric disorders
WO2008127515A1 (en) * 2007-03-01 2008-10-23 Cytologic, Inc. Compositions and method for enhancing immune responses in mammals
DK2953634T3 (da) 2013-02-07 2021-08-30 Massachusetts Gen Hospital Fremgangsmåder til udvidelse eller udtømning af regulerende t-celler
AU2020470781A1 (en) 2020-10-01 2023-05-18 Immunicom, Inc. Reduced leaching of a ligand
US11224858B1 (en) 2020-10-01 2022-01-18 Immunicom, Inc. Reduced leaching of a ligand
WO2025163107A1 (en) 2024-02-01 2025-08-07 Institut Gustave Roussy Immune cells defective for znf217 and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07106158B2 (ja) * 1986-12-04 1995-11-15 サントリー株式会社 抗腫瘍活性を有する新規ポリペプチドおよびその製造法
CA2055168A1 (en) * 1990-11-21 1992-05-22 Walter Fiers Tnf-muteins

Also Published As

Publication number Publication date
US5486463A (en) 1996-01-23
ZA932177B (en) 1993-10-04
CN1079225A (zh) 1993-12-08
JPH07285997A (ja) 1995-10-31
MX9301700A (es) 1993-10-29
CZ283533B6 (cs) 1998-04-15
FI931488L (fi) 1993-10-03
HU9300843D0 (en) 1993-06-28
EP0563714A3 (en) 1993-11-10
NO931141D0 (no) 1993-03-26
SK376492A3 (en) 1995-06-07
FI931488A0 (fi) 1993-04-01
CN1037844C (zh) 1998-03-25
CZ376492A3 (en) 1994-01-19
CA2091313A1 (en) 1993-10-03
PL298345A1 (en) 1993-12-27
EP0563714A2 (en) 1993-10-06
FI931488A7 (fi) 1993-10-03
BR9301420A (pt) 1993-10-05
HUT69790A (en) 1995-09-28
NZ247265A (en) 1995-10-26
AU3561193A (en) 1993-10-07
IL105170A0 (en) 1993-07-08
AU659927B2 (en) 1995-06-01
UY23561A1 (es) 1993-09-20
TW260707B (cs) 1995-10-21

Similar Documents

Publication Publication Date Title
NO931141L (no) Tnf-muteiner
NO914541L (no) Fremgangsmaate ved fremstilling av tumor-nekrose-faktor-muteiner
Curry et al. Calcium uptake by sarcoplasmic reticulum of muscle from vitamin D-deficient rabbits
DK305885A (da) Tumornecrosefaktor og derivater og mutantformer deraf, frem. til frems. deraf, frem. til isolering deraf fra en blanding med andre proteiner,praeparater deraf, dna som koder derfor, dna'en inkorporeret i en replicerbar vektor og celle transformeret dermed
DK0559884T3 (da) Rekombinante virusvektorer til ekspression i muskelceller
CA2223433A1 (en) Ob protein compositions and methods
NO985975L (no) Blandinger og fremgangsmÕter for frembringelse av farmakologisk aktive preparater og anvendelser derav
IL85411A0 (en) Methods and deoxyribonucleic acid for the preparation of tissue factor protein
DE69027865D1 (de) ZUSAMMENSETZUNGEN enthaltend omega Conotoxin Peptide Derivate und deren Verwendung ZUR BEHANDLUNG VON ISCHÄMIE-ARTIGEN NEURONALEN SCHÄDIGUNGEN
BG86132A (bg) Производни на пиридазинамин
CY1111912T1 (el) Μεθοδος αναστολης της δραστηριοτητας των οστεοκλαστων
DE69535883D1 (de) Muteine von ifn-beta
KR960700062A (ko) 산성 pH에서의 안정성을 개선시키기 위해 변형된 올리고누클레오티드(OLIGONUCLEOTIDES MODIFIED TO IMPROVE STABILITY AT ACIC pH)
ATE60759T1 (de) Bisdimethoxymethyl(trimethoxybenzyl)isochinolinium salze, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NZ279963A (en) Human tissue inhibitor of metalloproteinase-4 (timp-4) and dna (rna) encoding polypeptide which may be derived from atcc 75946
BRPI9912819B8 (pt) vetor de expressão, micro-organismo transgênico, usos de uma molécula de ácido nucléico e de um fator de crescimento neurotrófico, bem como composições farmacêuticas compreendendo os mesmos
KR870700599A (ko) 카르복실산유도체, 그의 제조방법, 이화합물을 함유한 약제조성물 및 그의 용도
CA2107552A1 (en) Use of deprenyl to maintain, prevent loss, or recover nerve cell function
BR9912609A (pt) Métodos de uso de um análogo de somatostatina
NO982935L (no) Hyaluronsyre reseptor bindemiddel og anvendelse derav
CA2290739A1 (en) New bpc peptide salts with organo-protective activity, the process for their preparation and their use in therapy
EP0324447A3 (de) Mittel und Verfahren zur Herstellung eines rekombinanten, menschlichen Interleukin-1 alpha-Polypeptides
RU93005356A (ru) Tnf-мутеин
IE840977L (en) Pharmaceutical preparations
EP0670165A2 (en) Use of seminal ribonuclease as antimetastatic compound