NO924546L - Nye azaheterocyklylmetyl-kromaner - Google Patents

Nye azaheterocyklylmetyl-kromaner

Info

Publication number
NO924546L
NO924546L NO92924546A NO924546A NO924546L NO 924546 L NO924546 L NO 924546L NO 92924546 A NO92924546 A NO 92924546A NO 924546 A NO924546 A NO 924546A NO 924546 L NO924546 L NO 924546L
Authority
NO
Norway
Prior art keywords
azaheterocyclylmethyl
chromanes
new
appropriate
methylchromans
Prior art date
Application number
NO92924546A
Other languages
English (en)
Other versions
NO924546D0 (no
NO303174B1 (no
Inventor
Hans-Georg Heine
Rudolf Schone-Loop
Thomas Glasser
Jean Marie Vikto De Vry
Wolfgang Dompert
Henning Sommermeyer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO924546D0 publication Critical patent/NO924546D0/no
Publication of NO924546L publication Critical patent/NO924546L/no
Publication of NO303174B1 publication Critical patent/NO303174B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
NO924546A 1991-12-09 1992-11-25 Nye azaheterocyklylmetyl-kromaner, og anvendelse av disse for fremstilling av legemidler NO303174B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4140540A DE4140540A1 (de) 1991-12-09 1991-12-09 Neue azaheterocyclylmethyl-chromane

Publications (3)

Publication Number Publication Date
NO924546D0 NO924546D0 (no) 1992-11-25
NO924546L true NO924546L (no) 1993-06-10
NO303174B1 NO303174B1 (no) 1998-06-08

Family

ID=6446618

Family Applications (1)

Application Number Title Priority Date Filing Date
NO924546A NO303174B1 (no) 1991-12-09 1992-11-25 Nye azaheterocyklylmetyl-kromaner, og anvendelse av disse for fremstilling av legemidler

Country Status (22)

Country Link
US (5) US5371094A (no)
EP (1) EP0546388B1 (no)
JP (1) JP3220266B2 (no)
AT (1) ATE136030T1 (no)
AU (1) AU650182B2 (no)
CA (1) CA2084542A1 (no)
CZ (1) CZ283680B6 (no)
DE (2) DE4140540A1 (no)
DK (1) DK0546388T3 (no)
ES (1) ES2086623T3 (no)
FI (1) FI925549A (no)
GR (1) GR3019450T3 (no)
HU (1) HUT65427A (no)
IL (1) IL104006A (no)
MX (1) MX9206817A (no)
NO (1) NO303174B1 (no)
NZ (1) NZ245381A (no)
PH (1) PH31072A (no)
RU (1) RU2089549C1 (no)
SK (1) SK361392A3 (no)
TW (1) TW210339B (no)
ZA (1) ZA929498B (no)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4140542A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Piperdylmethyl substituierte chormanderivate
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
US5478934A (en) * 1994-11-23 1995-12-26 Yuan; Jun Certain 1-substituted aminomethyl imidazole and pyrrole derivatives: novel dopamine receptor subtype specific ligands
US6096763A (en) * 1995-02-23 2000-08-01 Merck & Co., Inc. α1a adrenergic receptor antagonists
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5658796A (en) * 1995-06-07 1997-08-19 Seprachem, Inc. Optical resolution of alkyl chroman-2-carboxylates
US5670667A (en) * 1995-07-25 1997-09-23 American Home Products Corporation Chroman-2-ylmethylamino derivatives
US5663194A (en) * 1995-07-25 1997-09-02 Mewshaw; Richard E. Chroman-2-ylmethylamino derivatives
US5684039A (en) * 1995-07-25 1997-11-04 American Home Products Corporation Chroman-2-ylmethylamino derivatives
IL119483A (en) 1995-11-06 1999-06-20 American Home Prod 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them
WO1998016530A1 (en) * 1996-10-15 1998-04-23 American Home Products Corporation AZAHETEROCYCLYMETHYL DERIVATIVES OF 2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e]INDOL-8-ONE
US5869490A (en) * 1996-10-15 1999-02-09 American Home Products Corporation Azaheterocyclymethyl derivatives of 2,3,8,9-tetrahydro-7h-1,4-dioxino (2,3-e) indol-8-one
US5750556A (en) * 1996-10-30 1998-05-12 American Home Products Corporation 2-(aminomethyl)-3,4,7,9-tetrahydro-2H-pyrano- 2,3-E!indol-8-ones and derivatives
US6331543B1 (en) * 1996-11-01 2001-12-18 Nitromed, Inc. Nitrosated and nitrosylated phosphodiesterase inhibitors, compositions and methods of use
SE9702716D0 (sv) * 1997-07-15 1997-07-15 Ross Nicholas Waters Substituted phenylazacycloalkanes in the treatment of cognitive disorders
US6004982A (en) * 1997-09-15 1999-12-21 Hoechst Marion Roussel, Inc. 4-piperidinyl) H-2-benzopyran derivatives useful as antipsychotic agents
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
US6169185B1 (en) 1999-02-25 2001-01-02 Day-Glo Color Corp. Ink jet printing inks
DK1187829T3 (da) * 1999-06-02 2004-04-13 Janssen Pharmaceutica Nv Aminoalkylsubstituerede (benzodioxan, benzofuran eller benzopyran) derivater
EP1187831B1 (en) 1999-06-02 2004-10-13 Janssen Pharmaceutica N.V. Pyrrolidinyl, piperidinyl or homopiperidinyl substituted (benzodioxan, benzofuran or benzopyran) derivatives
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6458802B1 (en) 2001-03-14 2002-10-01 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-dioxino [2,3-f]quinoline
US7041683B2 (en) * 2001-04-24 2006-05-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan
WO2002085896A1 (en) 2001-04-24 2002-10-31 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan
US6803368B2 (en) 2001-04-25 2004-10-12 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diaza-cyclopenta[a]naphthalene
WO2002088145A1 (en) 2001-04-26 2002-11-07 Wyeth AZABICYCLYLMETHYL DERIVATIVES OF 7,8-DIHYDRO-1,6,9-TRIOXA-3-AZACYCLOPENTA[a]NAPHTHALENE AS 5-HT1A ANTAGONISTS
US6800641B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-2,3-diaza-cyclopenta[a]naphthalene
US6656947B2 (en) 2001-04-26 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinazoline
US6627639B2 (en) 2001-04-26 2003-09-30 Wyeth Uses for indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino-[2,3-e]indole
ATE334989T1 (de) 2001-04-26 2006-08-15 Wyeth Corp Antidepressive azaheterocyclylmethyl-derivate von 2,3-dihydro-1,4-dioxino 2,3-föchinoxalin
DE60206048T2 (de) 2001-04-26 2006-07-13 Wyeth Antidepressive (sssri) azaheterocyclylmethylderivate von 7,8-dihydro-3h-6,9-dioxa-1,3-diazacyclopenta [a] naphthalin
US6861427B2 (en) * 2001-04-26 2005-03-01 Wyeth Azabicyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]quinoline as 5-HT1A antagonists
US6706736B2 (en) 2001-04-26 2004-03-16 Wyeth Antidepressant azaheterocyclylmethyl derivatives of oxaheterocycle-fused-[1,4]-benzodioxans
US6927226B2 (en) * 2001-04-26 2005-08-09 Wyeth Antidepressant azaheterocyclymethyl derivatives of 7,8-dihydro-3H-6,9-dioxa-1,3-diazacyclopenta[a]naphthalene
US7008944B2 (en) * 2001-04-26 2006-03-07 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-Dioxino[2,3-f]quinoxaline
US6800642B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-2,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
US6821981B2 (en) 2001-04-26 2004-11-23 Wyeth Azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-dioxino[2,3-f]-quinoline as 5-HT1A antagonists
ATE279415T1 (de) 2001-04-26 2004-10-15 Wyeth Corp Antidepressiv wirksame azaheterocyclymethyl- derivative von oxaheterocycyl-anellierten (1,4)- benzodioxanen
US6861434B2 (en) 2001-04-26 2005-03-01 Wyeth Antipsychotic aminomethyl derivatives of 1,3,7,8-tetrahydro-6,9-dioxa-1,3-diaza-cyclopenta[a]-naphthalen-2-one
US6593350B2 (en) 2001-04-26 2003-07-15 Wyeth Antidepressant indoletetrahydropyridine derivatives of 2,3-dihydro-7H-[1,4]dioxino[2,3-e]indole
US6800648B2 (en) 2001-04-26 2004-10-05 Wyeth Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one
US6906206B2 (en) * 2001-04-30 2005-06-14 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6617334B2 (en) 2001-04-30 2003-09-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene
BR0209407A (pt) 2001-04-30 2004-07-06 Wyeth Corp Antidepressivos de azaheterociclilmetila derivados de 7,8-dihidro-1,6,9-trioxa-3-aza-ciclopenta[a[]naftaleno , método de tratamento usando tais compostos e processo para prepará-los
US6555560B2 (en) 2001-04-30 2003-04-29 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4,5-trioxa-phenanthrene
US6815448B2 (en) 2001-05-07 2004-11-09 Wyeth Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists
JP2004530693A (ja) * 2001-05-17 2004-10-07 ワイス ２，３−ジヒドロ−１，４−ジオキシノ−［２，３−ｆ］キノリンの誘導体を合成する工程
US6541502B1 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
US6541501B2 (en) 2001-07-20 2003-04-01 Wyeth 2-(aminomethyl)-tetrahydro-9-oxa-1,3-diaza-cyclopenta[a]-naphthalenyl derivatives with antipsychotic activity
AR035083A1 (es) 2001-07-25 2004-04-14 Wyeth Corp Derivados azaheterociclilmetilicos de 7,8-dihidro-6h-5-oxa-1-aza-fenantreno, composiciones farmaceuticas, el uso de dichos derivados para la preparacion de un medicamento antidepresivo e intermediarios
US6667322B2 (en) 2001-10-05 2003-12-23 Wyeth Antidepressant chroman and chromene derivatives of 3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
BR0213030A (pt) 2001-10-05 2004-10-05 Wyeth Corp Processo estereoespecìfico para a sìntese de derivados de 2-il cromano
EP1432695A1 (en) 2001-10-05 2004-06-30 Wyeth A process for the stereoselective synthesis of 2-hydroxymethyl-chromans
WO2003040382A1 (fr) * 2001-11-09 2003-05-15 Kaneka Corporation Procede de production d'un derive de chromane optiquement actif et d'un produit intermediaire
US7115644B2 (en) * 2002-09-13 2006-10-03 Boehringer Ingelheim Pharmaceuticals Inc. Heterocyclic compounds
KR100602191B1 (ko) * 2004-03-10 2006-07-19 한국화학연구원 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체
KR100704009B1 (ko) * 2005-08-30 2007-04-04 한국화학연구원 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체
MX2008010953A (es) * 2006-02-28 2008-09-08 Amgen Inc Derivados de cinolina y quinoxalina como inhibidores de la fosfodiesterasa 10.
TW200811182A (en) * 2006-05-25 2008-03-01 Wyeth Corp Oxindoledioxans, synthesis thereof, and intermediates thereto
RU2652119C1 (ru) * 2016-12-14 2018-04-25 федеральное государственное бюджетное образовательное учреждение высшего образования "Самарский государственный технический университет" Способ получения производных хроман-2-аминов

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826835A (en) * 1971-01-08 1974-07-30 Ciba Geigy Corp 8-benzofurylmethyl-1,3,8-triazaspiro(4,5)decanes as neuroleptics
US4179510A (en) * 1977-10-31 1979-12-18 The Upjohn Company Methods of treating psychosis
US4153612A (en) * 1977-10-31 1979-05-08 The Upjohn Company 2-Benzoxepins
US4711960A (en) * 1977-10-31 1987-12-08 The Upjohn Company Isochromans
US4556656A (en) * 1978-10-23 1985-12-03 The Upjohn Company 2-Benzoxepins
DE3124366A1 (de) * 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
US4826848A (en) * 1985-04-15 1989-05-02 Janssen Pharmaceutica N.V. Antidepressive substituted N-[(4-piperidinyl)alkyl] bicyclic condensed oxazol- and thiazolamines
GB8515389D0 (en) * 1985-06-18 1985-07-17 Ici Plc Heterocyclic compounds
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
US5300523A (en) * 1988-07-28 1994-04-05 Bayer Aktiengesellschaft Substituted aminomethyltetralins and their heterocyclic analogues
DE4140542A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Piperdylmethyl substituierte chormanderivate

Also Published As

Publication number Publication date
HUT65427A (en) 1994-06-28
CA2084542A1 (en) 1993-06-10
ES2086623T3 (es) 1996-07-01
FI925549A0 (fi) 1992-12-07
IL104006A0 (en) 1993-05-13
NZ245381A (en) 1995-03-28
ZA929498B (en) 1993-06-10
AU650182B2 (en) 1994-06-09
DK0546388T3 (da) 1996-07-29
NO924546D0 (no) 1992-11-25
DE4140540A1 (de) 1993-06-17
HU9203894D0 (en) 1993-03-29
CZ283680B6 (cs) 1998-06-17
US5545643A (en) 1996-08-13
SK278553B6 (en) 1997-09-10
PH31072A (en) 1998-02-05
FI925549A (fi) 1993-06-10
JP3220266B2 (ja) 2001-10-22
US5696137A (en) 1997-12-09
US5371094A (en) 1994-12-06
GR3019450T3 (en) 1996-06-30
MX9206817A (es) 1994-06-30
SK361392A3 (en) 1997-09-10
ATE136030T1 (de) 1996-04-15
NO303174B1 (no) 1998-06-08
EP0546388A1 (de) 1993-06-16
EP0546388B1 (de) 1996-03-27
US5696136A (en) 1997-12-09
US5693653A (en) 1997-12-02
DE59205846D1 (de) 1996-05-02
RU2089549C1 (ru) 1997-09-10
AU2993892A (en) 1993-06-10
TW210339B (no) 1993-08-01
CZ361392A3 (en) 1993-10-13
IL104006A (en) 1997-02-18
JPH05279357A (ja) 1993-10-26

Similar Documents

Publication Publication Date Title
NO924546D0 (no) Nye azaheterocyklymentyl-chromaner
NO961687D0 (no) Nye (R)-5-karbamoyl-8-fluor-3-N,N-disubstituerte-amino-3,4-dihydro-2H-1-benzopyraner
DK0546389T3 (da) Piperidylmethylsubstituerede chromanderivater som virksomme stoffer til behandling af sygdomme i centralnervesystemet
ES2125879T3 (es) Triazaespirodecanona-metilcromanos para el tratamiento de enfermedades del sistema nervioso central.
NO303825B1 (no) Imidazolyl-substituerte cykloheksanderivater, legemidler inneholdende derivatene, anvendelse av derivatene for fremstilling av legemidler samt mellomprodukter for fremstilling av derivatene
NO932502L (no) Nye fosfolipidderivater