NO923581L - Sykliske substituerte imidazolylpropensyrederivater - Google Patents

Sykliske substituerte imidazolylpropensyrederivater

Info

Publication number
NO923581L
NO923581L NO92923581A NO923581A NO923581L NO 923581 L NO923581 L NO 923581L NO 92923581 A NO92923581 A NO 92923581A NO 923581 A NO923581 A NO 923581A NO 923581 L NO923581 L NO 923581L
Authority
NO
Norway
Prior art keywords
acid derivatives
imidazolylpropenic
cyclic substituted
propenoic acid
substituted imidazolyl
Prior art date
Application number
NO92923581A
Other languages
English (en)
Norwegian (no)
Other versions
NO923581D0 (no
Inventor
Thomas Kraemer
Juergen Dressel
Rudolf Hanko
Walter Huebsch
Ulrich Mueller
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Johannes-Peter Stasch
Andreas Knorr
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO923581D0 publication Critical patent/NO923581D0/no
Publication of NO923581L publication Critical patent/NO923581L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO92923581A 1991-10-01 1992-09-15 Sykliske substituerte imidazolylpropensyrederivater NO923581L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132633A DE4132633A1 (de) 1991-10-01 1991-10-01 Cyclisch substituierte imidazolyl-propensaeurederivate

Publications (2)

Publication Number Publication Date
NO923581D0 NO923581D0 (no) 1992-09-15
NO923581L true NO923581L (no) 1993-04-02

Family

ID=6441875

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923581A NO923581L (no) 1991-10-01 1992-09-15 Sykliske substituerte imidazolylpropensyrederivater

Country Status (14)

Country Link
US (1) US5225428A (enExample)
EP (1) EP0535465A1 (enExample)
JP (1) JPH05213937A (enExample)
KR (1) KR930007938A (enExample)
AU (1) AU646762B2 (enExample)
CA (1) CA2079266A1 (enExample)
CZ (1) CZ297792A3 (enExample)
DE (1) DE4132633A1 (enExample)
HU (1) HUT62578A (enExample)
IL (1) IL103292A0 (enExample)
MX (1) MX9205434A (enExample)
NO (1) NO923581L (enExample)
TW (1) TW206966B (enExample)
ZA (1) ZA927499B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
JP3883205B2 (ja) * 1994-03-29 2007-02-21 メルク エンド カンパニー インコーポレーテッド アンギオテンシン▲ｉｉ▼レセプタ遮断イミダゾールによるアテローム性動脈硬化症の治療
ES2154191B1 (es) * 1998-11-24 2001-10-16 Ferrer Int Nuevos acetales derivados de los 2-alquil-5-halo-3-(2'-(tetrazol-5-il)-bifenil-4-ilmetil)-3h-imidazol-4-carbaldehidos.
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
EP2080756A3 (de) * 2005-02-03 2011-02-16 Ratiopharm GmbH Verfahren zur Herstellung von Losartan
EP1741711A1 (en) * 2005-07-04 2007-01-10 KRKA, D.D., Novo Mesto A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1H-imidazole-5-carbaldehydes
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
WO2008151257A2 (en) 2007-06-04 2008-12-11 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2730603C (en) 2008-07-16 2019-09-24 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same
CN107325052B (zh) * 2017-06-19 2020-01-10 广东药科大学 一类具有抗癌活性的咪唑酯类化合物及其衍生物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
DE69033469T2 (de) * 1989-06-14 2000-09-07 Smithkline Beecham Corp., Philadelphia Imidazoalkensäure
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
FI916130A7 (fi) * 1989-06-30 1991-12-27 Du Pont Aryylisubstituoituja imidatsoleja
FI916129A7 (fi) * 1989-06-30 1991-12-27 Du Pont Substituoituja imidatsoleja
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate

Also Published As

Publication number Publication date
AU2602592A (en) 1993-04-08
NO923581D0 (no) 1992-09-15
HU9203125D0 (en) 1992-12-28
IL103292A0 (en) 1993-02-21
JPH05213937A (ja) 1993-08-24
DE4132633A1 (de) 1993-04-08
KR930007938A (ko) 1993-05-20
CZ297792A3 (en) 1993-04-14
ZA927499B (en) 1993-05-03
EP0535465A1 (de) 1993-04-07
AU646762B2 (en) 1994-03-03
MX9205434A (es) 1993-04-01
TW206966B (enExample) 1993-06-01
US5225428A (en) 1993-07-06
HUT62578A (en) 1993-05-28
CA2079266A1 (en) 1993-04-02

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