MX9205434A - Derivados del acido imidazolil-propenico substituidos ciclicamente y procedimiento para su fabricacion. - Google Patents

Derivados del acido imidazolil-propenico substituidos ciclicamente y procedimiento para su fabricacion.

Info

Publication number
MX9205434A
MX9205434A MX9205434A MX9205434A MX9205434A MX 9205434 A MX9205434 A MX 9205434A MX 9205434 A MX9205434 A MX 9205434A MX 9205434 A MX9205434 A MX 9205434A MX 9205434 A MX9205434 A MX 9205434A
Authority
MX
Mexico
Prior art keywords
derivatives
procedure
manufacture
substituted imidazolyl
propenic acid
Prior art date
Application number
MX9205434A
Other languages
English (en)
Inventor
Thomas Kramer
Jurgen Dressel
Rudolf Hanko
Walter Hubsch
Ulrich Muller
Matthias Muller-Gliemann
Martin Beuck Stanislav Kazda
Johannes-Peter Stasch
Andreas Knorr Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9205434A publication Critical patent/MX9205434A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MX9205434A 1991-10-01 1992-09-24 Derivados del acido imidazolil-propenico substituidos ciclicamente y procedimiento para su fabricacion. MX9205434A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132633A DE4132633A1 (de) 1991-10-01 1991-10-01 Cyclisch substituierte imidazolyl-propensaeurederivate

Publications (1)

Publication Number Publication Date
MX9205434A true MX9205434A (es) 1993-04-01

Family

ID=6441875

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9205434A MX9205434A (es) 1991-10-01 1992-09-24 Derivados del acido imidazolil-propenico substituidos ciclicamente y procedimiento para su fabricacion.

Country Status (14)

Country Link
US (1) US5225428A (es)
EP (1) EP0535465A1 (es)
JP (1) JPH05213937A (es)
KR (1) KR930007938A (es)
AU (1) AU646762B2 (es)
CA (1) CA2079266A1 (es)
CZ (1) CZ297792A3 (es)
DE (1) DE4132633A1 (es)
HU (1) HUT62578A (es)
IL (1) IL103292A0 (es)
MX (1) MX9205434A (es)
NO (1) NO923581L (es)
TW (1) TW206966B (es)
ZA (1) ZA927499B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
AU696868B2 (en) * 1994-03-29 1998-09-17 Merck & Co., Inc. Treatment of atherosclerosis with angiotensin II receptor blocking imidazoles
ES2154191B1 (es) * 1998-11-24 2001-10-16 Ferrer Int Nuevos acetales derivados de los 2-alquil-5-halo-3-(2'-(tetrazol-5-il)-bifenil-4-ilmetil)-3h-imidazol-4-carbaldehidos.
US6465502B1 (en) 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
ATE441637T1 (de) * 2005-02-03 2009-09-15 Ratiopharm Gmbh Verfahren zur herstellung von losartan
EP1741711A1 (en) * 2005-07-04 2007-01-10 KRKA, D.D., Novo Mesto A process for the preparation of losartan derivatives by chlorination and reduction of the respective 1H-imidazole-5-carbaldehydes
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
WO2010009319A2 (en) 2008-07-16 2010-01-21 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
CN107325052B (zh) * 2017-06-19 2020-01-10 广东药科大学 一类具有抗癌活性的咪唑酯类化合物及其衍生物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
SG52330A1 (en) * 1989-06-14 1998-09-28 Smithkline Beecham Corp Imidazolyl-alkenoic acids
DE69025473T2 (de) * 1989-06-30 1996-10-17 Du Pont Substituierte imidazole und ihre verwendung als hemmmstoff fur angiotensin ii
AU645022B2 (en) * 1989-06-30 1994-01-06 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
US5137902A (en) * 1990-07-13 1992-08-11 E. I. Du Pont De Nemours And Company 4-alkylimidazole derivatives and anti-hypertensive use thereof
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate

Also Published As

Publication number Publication date
CA2079266A1 (en) 1993-04-02
US5225428A (en) 1993-07-06
TW206966B (es) 1993-06-01
ZA927499B (en) 1993-05-03
IL103292A0 (en) 1993-02-21
JPH05213937A (ja) 1993-08-24
CZ297792A3 (en) 1993-04-14
AU646762B2 (en) 1994-03-03
HU9203125D0 (en) 1992-12-28
NO923581L (no) 1993-04-02
HUT62578A (en) 1993-05-28
NO923581D0 (no) 1992-09-15
KR930007938A (ko) 1993-05-20
EP0535465A1 (de) 1993-04-07
DE4132633A1 (de) 1993-04-08
AU2602592A (en) 1993-04-08

Similar Documents

Publication Publication Date Title
MX174542B (es) Procedimiento para la polimerizacion del acido itaconico
MX9206450A (es) Proceso para la produccion de isoleucina-l.
NO921777D0 (no) Fremgangsmaate for fremstilling av isoparaffiner
DOP1992004859A (es) Procedimiento para la produccion de n fenilsulfonil-npirimidil y triacinil-urea
MX9205434A (es) Derivados del acido imidazolil-propenico substituidos ciclicamente y procedimiento para su fabricacion.
MX9205435A (es) Derivados del acido imidazolil-propenico substituidos y procedimiento para su fabricacion.
MX9202982A (es) Derivados de los acidos quinolon - y naftiridon - carboxilicos, procedimiento para su obtencion y medicamentos que los contienen.
MX9202022A (es) Derivados de pirazina y proceso para su preparacion.
MX9203903A (es) Espesadores fibridos y proceso para su fabricacion.
MX9202583A (es) Procedimiento mejorado para la produccion de glicosil transferasas.
MX9205436A (es) Derivados del acido imidazolil-propenico y procedimiento para su fabricacion
MX9101735A (es) Aparato y procedimiento para la fabricacion de acido peroxomonosulfurico
IT8421068A0 (it) Derivati di acido poliidrossibenzoico ad azione farmaceutica.
ES2018667B3 (es) Derivados del acido 4-qionolon-3-carboxilico, procedimiento para su obtencion y preparados farmaceuticos que los contienen.
MX9203836A (es) Derivados de acido-4-amino-3-hidroxicarboxilico y proceso para su preparacion.
ES537480A0 (es) Procedimiento para la fabricacion de la reductasa del acido 2, 5-diceto-d-gluconico
MX9101544A (es) Procedimiento para la produccion de polifluoroolefinas
NO920467L (no) Framgangsmaate for framstilling av oppmalte naeringsmidler
MX158754A (es) Procedimiento para la preparacion de compuestos derivados y sus esteroisomeros,del acido 16-fenoxi-y 16 fenoxi;-substituido-prostatrienoico
IT8022565A0 (it) Procedimento per la produzione di acido cloridico ed amoniaca.
MX9206612A (es) Amidas del acido quinolilmetoxifenilacetico, procedimiento para su fabricacion y medicamento que las contiene
MX9100722A (es) Derivados del acido 4-cloro-4,4-difluorotiobutirico y procedimiento para su preparacion
MX9204109A (es) Derivados de acido 2-(imidazol-1-il)-2-bencil-etiliden-aminoxialcanoico y proceso para su preparacion.
MX9204847A (es) Procedimiento para la produccion de acetato de metilo.
MX9206611A (es) Acilamidas y ureas del acido quinolilmetoxifenilacetico, procedimiento para su fabricacion y medicamento que las contiene