NO921141L - Indolderivater, fremgangsmaate for deres fremstilling og anvendelse derav - Google Patents
Indolderivater, fremgangsmaate for deres fremstilling og anvendelse deravInfo
- Publication number
- NO921141L NO921141L NO92921141A NO921141A NO921141L NO 921141 L NO921141 L NO 921141L NO 92921141 A NO92921141 A NO 92921141A NO 921141 A NO921141 A NO 921141A NO 921141 L NO921141 L NO 921141L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- alkylamino
- phenyl
- benzyl
- optionally substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9103618A FR2674522B1 (fr) | 1991-03-26 | 1991-03-26 | Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO921141D0 NO921141D0 (no) | 1992-03-24 |
| NO921141L true NO921141L (no) | 1992-09-28 |
| NO178260B NO178260B (no) | 1995-11-13 |
| NO178260C NO178260C (no) | 1996-02-21 |
Family
ID=9411107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO921141A NO178260C (no) | 1991-03-26 | 1992-03-24 | Indolderivater, mellomproduktforbindelser for deres fremstilling, anvendelse derav samt farmasöytisk preparat |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5219859A (no) |
| EP (1) | EP0506532B1 (no) |
| JP (1) | JPH0597802A (no) |
| KR (1) | KR950007753B1 (no) |
| AT (1) | ATE111078T1 (no) |
| AU (1) | AU658609B2 (no) |
| CA (1) | CA2063170A1 (no) |
| CS (1) | CS89592A3 (no) |
| DE (1) | DE69200378T2 (no) |
| DK (1) | DK0506532T3 (no) |
| ES (1) | ES2064149T3 (no) |
| FR (1) | FR2674522B1 (no) |
| HU (1) | HUT65489A (no) |
| IE (1) | IE65366B1 (no) |
| IL (1) | IL101248A (no) |
| MA (1) | MA22474A1 (no) |
| MX (1) | MX9201365A (no) |
| NO (1) | NO178260C (no) |
| NZ (1) | NZ242078A (no) |
| OA (1) | OA09573A (no) |
| RU (1) | RU2074179C1 (no) |
| SI (1) | SI9210305A (no) |
| TN (1) | TNSN92022A1 (no) |
| YU (1) | YU30592A (no) |
| ZA (1) | ZA922163B (no) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687402B1 (fr) * | 1992-02-14 | 1995-06-30 | Lipha | Nouveaux azaindoles, procedes de preparation et medicaments les contenant. |
| WO1993024458A1 (en) * | 1992-05-28 | 1993-12-09 | Pfizer Inc. | New n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a:cholesterol acyl transferase (acat) |
| NZ250916A (en) * | 1993-02-27 | 1995-08-28 | Nihon Nohyaku Co Ltd | N-heteroaryl-n'-phenylureas, their use as acat inhibitors |
| IL109568A0 (en) * | 1993-05-19 | 1994-08-26 | Fujisawa Pharmaceutical Co | Urea derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
| DE4401893A1 (de) * | 1994-01-24 | 1995-07-27 | Bayer Ag | Substituierte Arylharnstoffe |
| JP3720395B2 (ja) | 1994-09-20 | 2005-11-24 | 京都薬品工業株式会社 | 新規ヘテロ環誘導体、その製造方法およびその医薬用途 |
| DE69523182T2 (de) * | 1995-06-06 | 2002-02-07 | Pfizer | Substituierte n-(indol-2-carbonyl)-glycinamide und derivate als glycogen phosphorylase inhibitoren |
| MX9709874A (es) | 1995-06-06 | 1998-03-31 | Pfizer | N-(INDOL-2-CARBONIL) beta-ALANILAMIDAS SUSTITUIDAS Y DERIVADOS COMO INHIBIDORES DE GLUCOGENO FOSFORILASA, USO DE LOS MISMOS Y COMPOSICIONES QUE LOS CONTIENEN. |
| KR100241643B1 (ko) * | 1995-06-06 | 2000-03-02 | 디. 제이. 우드 | 당뇨병치료제인 치환된 N-(인돌-2-카르보닐)-β-알라님아미드 및 그의 유도체 |
| AU679887B2 (en) * | 1995-09-11 | 1997-07-10 | Nihon Nohyaku Co., Ltd. | Azole derivatives, their use, production and usage |
| DE69617731T2 (de) * | 1995-10-05 | 2002-08-08 | Kyoto Pharmaceutical Industries, Ltd. | Neue heterozyklische derivate und ihre medizinische anwendung |
| EP0773218A1 (en) * | 1995-11-13 | 1997-05-14 | Mitsubishi Chemical Corporation | N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis |
| FR2763334A1 (fr) * | 1997-05-13 | 1998-11-20 | Lipha | Derives anthraniliques |
| CA2304974C (en) * | 1997-12-16 | 2005-10-25 | Warner-Lambert Company | 1-substituted-1-aminomethyl-cycloalkane derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
| CN1210268C (zh) * | 1997-12-16 | 2005-07-13 | 沃尼尔·朗伯公司 | ((环)烷基取代的)－γ－氨基丁酸衍生物(=GABA类似物),其制备和在治疗神经病中的用途 |
| US6545022B1 (en) * | 1997-12-16 | 2003-04-08 | Pfizer Inc. | 4(3)substituted-4(3)-aminomethyl-(thio)pyran or piperidine derivatives (=gabapentin analogues), their preparation and their use in the treatment of neurological disorders |
| SK282727B6 (sk) | 1997-12-19 | 2002-11-06 | Slovakofarma, A. S. | 1,3-Disubstituované močoviny - inhibítory ACAT a spôsob ich prípravy |
| US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
| WO2002048150A2 (en) | 2000-11-02 | 2002-06-20 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Agents useful for reducing amyloid precursor protein and treating demantia and methods of use thereof |
| BR0309764A (pt) * | 2002-05-03 | 2005-02-15 | Warner Lambert Co | Antagonistas de bombesina |
| EP1541553B1 (en) * | 2002-07-17 | 2010-06-02 | Kyoto Pharmaceutical Industries, Ltd. | Indoline compound and medicinal use thereof |
| US7595403B2 (en) | 2003-04-01 | 2009-09-29 | Eli Lilly And Company | Benzisothiazol-3-one-carboxylic acid amides as phospholipase inhibitors |
| WO2007062998A1 (en) | 2005-11-30 | 2007-06-07 | F. Hoffmann-La Roche Ag | 3-amino-2-arylpropyl azaindoles and uses thereof |
| BRPI0619263A2 (pt) | 2005-11-30 | 2011-09-27 | Hoffmann La Roche | indóis de 3-amino-1-arilpropila e indóis aza-substituìdos, métodos para prepará-los, composição farmacêutica e uso dos referidos indóis |
| RU2361581C2 (ru) * | 2007-09-14 | 2009-07-20 | Закрытое Акционерное Общество "Мастерклон" | Фармацевтическая композиция, обладающая противодиабетической, гиполипидемической, гипогликемической и гипохолестеринемической активностью, способ ее получения и способы лечения указанных заболеваний |
| SK287385B6 (sk) | 2007-11-27 | 2010-08-09 | Hameln-Rds, A. S. | 1,3-Disubstituované močoviny, spôsob ich prípravy a použitia |
| CN104628621A (zh) * | 2015-01-22 | 2015-05-20 | 湖南华腾制药有限公司 | 一种氟取代吲哚衍生物的制备方法 |
| KR102646172B1 (ko) | 2017-06-26 | 2024-03-13 | 루넬라 바이오테크 인코포레이티드 | 미토케토신: 암 세포에서 케톤 대사를 표적화하는 미토콘드리아-기반의 치료제 |
| WO2020176599A1 (en) | 2019-02-27 | 2020-09-03 | The Regents Of The University Of California | Azepino-indoles and other heterocycles for treating brain disorders |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55151505A (en) * | 1979-05-14 | 1980-11-26 | Kuraray Co Ltd | Indole agricultural and horticultural fungicide |
| ZA88498B (en) * | 1987-02-02 | 1989-10-25 | Lilly Co Eli | Alkylmelatonins |
| EP0375133A1 (en) * | 1988-11-14 | 1990-06-27 | The Upjohn Company | Alpha-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents |
| PH30133A (en) * | 1989-09-07 | 1997-01-21 | Abbott Lab | Indole-, benzofuran-, and benzothiophene-containing lipoxygenase inhibiting compounds |
| MX22406A (es) * | 1989-09-15 | 1994-01-31 | Pfizer | Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat). |
| ATE130002T1 (de) * | 1990-08-13 | 1995-11-15 | Hoechst Roussel Pharma | 1-(pyridinylalkyl)-1h-indole, -indoline und analoge. |
| FR2680366B1 (fr) * | 1991-08-13 | 1995-01-20 | Adir | Nouveaux derives d'arylethylamines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| WO1993005020A1 (en) * | 1991-09-06 | 1993-03-18 | Merck & Co., Inc. | Indoles as inhibitors of hiv reverse transcriptase |
-
1991
- 1991-03-26 FR FR9103618A patent/FR2674522B1/fr not_active Expired - Fee Related
-
1992
- 1992-03-16 IL IL10124892A patent/IL101248A/en not_active IP Right Cessation
- 1992-03-17 CA CA002063170A patent/CA2063170A1/en not_active Abandoned
- 1992-03-20 DK DK92400764.4T patent/DK0506532T3/da active
- 1992-03-20 US US07/855,544 patent/US5219859A/en not_active Expired - Fee Related
- 1992-03-20 EP EP92400764A patent/EP0506532B1/fr not_active Expired - Lifetime
- 1992-03-20 AT AT92400764T patent/ATE111078T1/de active
- 1992-03-20 NZ NZ242078A patent/NZ242078A/en unknown
- 1992-03-20 ES ES92400764T patent/ES2064149T3/es not_active Expired - Lifetime
- 1992-03-20 DE DE69200378T patent/DE69200378T2/de not_active Expired - Fee Related
- 1992-03-20 AU AU13094/92A patent/AU658609B2/en not_active Ceased
- 1992-03-23 MA MA22763A patent/MA22474A1/fr unknown
- 1992-03-24 IE IE920937A patent/IE65366B1/en not_active IP Right Cessation
- 1992-03-24 NO NO921141A patent/NO178260C/no unknown
- 1992-03-25 JP JP4067252A patent/JPH0597802A/ja active Pending
- 1992-03-25 CS CS92895A patent/CS89592A3/cs unknown
- 1992-03-25 RU SU925011235A patent/RU2074179C1/ru active
- 1992-03-25 HU HU9200997A patent/HUT65489A/hu unknown
- 1992-03-25 ZA ZA922163A patent/ZA922163B/xx unknown
- 1992-03-26 TN TNTNSN92022A patent/TNSN92022A1/fr unknown
- 1992-03-26 SI SI9210305A patent/SI9210305A/sl unknown
- 1992-03-26 MX MX9201365A patent/MX9201365A/es not_active IP Right Cessation
- 1992-03-26 KR KR1019920005020A patent/KR950007753B1/ko not_active IP Right Cessation
- 1992-03-26 YU YU30592A patent/YU30592A/sh unknown
- 1992-03-26 OA OA60177A patent/OA09573A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR950007753B1 (ko) | 1995-07-14 |
| CA2063170A1 (en) | 1992-09-27 |
| OA09573A (fr) | 1993-01-31 |
| TNSN92022A1 (fr) | 1993-06-08 |
| ATE111078T1 (de) | 1994-09-15 |
| IL101248A0 (en) | 1992-11-15 |
| DK0506532T3 (da) | 1995-02-20 |
| HUT65489A (en) | 1994-06-28 |
| NO921141D0 (no) | 1992-03-24 |
| DE69200378T2 (de) | 1995-03-09 |
| HU9200997D0 (en) | 1992-05-28 |
| ZA922163B (en) | 1993-09-27 |
| FR2674522B1 (fr) | 1993-07-16 |
| IE920937A1 (en) | 1992-10-07 |
| NO178260C (no) | 1996-02-21 |
| US5219859A (en) | 1993-06-15 |
| DE69200378D1 (de) | 1994-10-13 |
| IL101248A (en) | 1996-12-05 |
| YU30592A (sh) | 1994-12-28 |
| EP0506532A1 (fr) | 1992-09-30 |
| RU2074179C1 (ru) | 1997-02-27 |
| JPH0597802A (ja) | 1993-04-20 |
| IE65366B1 (en) | 1995-10-18 |
| CS89592A3 (en) | 1992-10-14 |
| MX9201365A (es) | 1992-10-01 |
| SI9210305A (en) | 1996-02-29 |
| FR2674522A1 (fr) | 1992-10-02 |
| EP0506532B1 (fr) | 1994-09-07 |
| KR920018022A (ko) | 1992-10-21 |
| AU1309492A (en) | 1992-10-01 |
| NZ242078A (en) | 1994-10-26 |
| MA22474A1 (fr) | 1992-10-01 |
| ES2064149T3 (es) | 1995-01-16 |
| AU658609B2 (en) | 1995-04-27 |
| NO178260B (no) | 1995-11-13 |
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