NO914979D0 - Tetra-aza-makrosykliske forbindelser, fremgangsmaate for deres fremstilling og anvendelse for avbilding ved magnetisk resonans - Google Patents

Tetra-aza-makrosykliske forbindelser, fremgangsmaate for deres fremstilling og anvendelse for avbilding ved magnetisk resonans

Info

Publication number
NO914979D0
NO914979D0 NO914979A NO914979A NO914979D0 NO 914979 D0 NO914979 D0 NO 914979D0 NO 914979 A NO914979 A NO 914979A NO 914979 A NO914979 A NO 914979A NO 914979 D0 NO914979 D0 NO 914979D0
Authority
NO
Norway
Prior art keywords
group
alk
hydrogen atom
different
same
Prior art date
Application number
NO914979A
Other languages
English (en)
Other versions
NO914979L (no
Inventor
David Parker
Nigel Robert Arnold Beeley
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909008724A external-priority patent/GB9008724D0/en
Priority claimed from GB909008720A external-priority patent/GB9008720D0/en
Priority claimed from GB909017148A external-priority patent/GB9017148D0/en
Priority claimed from GB919104391A external-priority patent/GB9104391D0/en
Application filed by Celltech Ltd filed Critical Celltech Ltd
Publication of NO914979L publication Critical patent/NO914979L/no
Publication of NO914979D0 publication Critical patent/NO914979D0/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
NO914979A 1990-04-18 1991-12-17 Tetra-aza-makrosykliske forbindelser, fremgangsmaate for deres fremstilling og anvendelse for avbilding ved magnetisk resonans NO914979D0 (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB909008724A GB9008724D0 (en) 1990-04-18 1990-04-18 Chemical compounds
GB909008720A GB9008720D0 (en) 1990-04-18 1990-04-18 Diagnostic agents
GB909017148A GB9017148D0 (en) 1990-08-03 1990-08-03 Diagnostic agents
GB919104391A GB9104391D0 (en) 1991-03-01 1991-03-01 Diagnostic agents
PCT/GB1991/000605 WO1991016081A1 (en) 1990-04-18 1991-04-18 Tetra-aza macrocycles, processes for their preparation and their use in magnetic resonance imaging

Publications (2)

Publication Number Publication Date
NO914979L NO914979L (no) 1991-12-17
NO914979D0 true NO914979D0 (no) 1991-12-17

Family

ID=27450496

Family Applications (1)

Application Number Title Priority Date Filing Date
NO914979A NO914979D0 (no) 1990-04-18 1991-12-17 Tetra-aza-makrosykliske forbindelser, fremgangsmaate for deres fremstilling og anvendelse for avbilding ved magnetisk resonans

Country Status (15)

Country Link
US (1) US5653960A (no)
EP (1) EP0455380B1 (no)
JP (1) JPH05500969A (no)
AT (1) ATE147635T1 (no)
AU (1) AU654951B2 (no)
CA (1) CA2057868A1 (no)
DE (1) DE69124132T2 (no)
DK (1) DK0455380T3 (no)
FI (1) FI915916A0 (no)
GB (1) GB2250198B (no)
IE (1) IE911297A1 (no)
IL (1) IL97902A (no)
NO (1) NO914979D0 (no)
NZ (1) NZ237868A (no)
WO (1) WO1991016081A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342606A (en) * 1984-10-18 1994-08-30 Board Of Regents, The University Of Texas System Polyazamacrocyclic compounds for complexation of metal ions
AU654951B2 (en) * 1990-04-18 1994-12-01 Celltech Limited Tetra-aza macrocycles, processes for their preparation and their use in magnetic resonance imaging
US5409689A (en) * 1993-08-13 1995-04-25 Concat, Ltd. MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms
TW319763B (no) 1995-02-01 1997-11-11 Epix Medical Inc
EP0841951A2 (en) * 1995-06-26 1998-05-20 Concat Ltd. Compounds with chelation affinity and selectivity for first transition series elements, and their use in medical therapy and diagnosis
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
AU3225900A (en) * 1999-02-09 2000-08-29 Board Of Regents, The University Of Texas System Ph sensitive mri contrast agents
EP1191948A2 (en) 1999-06-11 2002-04-03 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
RU2311413C2 (ru) * 2000-09-29 2007-11-27 Анормед, Инк. Циклические полиамины, содержащие в кольце n атомов азота, защищенных по принципу "все, кроме одного (n-1)", и способы их получения
JP2004536034A (ja) * 2001-01-08 2004-12-02 ネオルクス コーポレイション 治療的および診断的化合物、組成物および方法
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
WO2006045546A1 (en) * 2004-10-20 2006-05-04 Therapharm Gmbh Method of preparing or synthesizing polyazamacrocycle derivatives

Family Cites Families (23)

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Publication number Priority date Publication date Assignee Title
DE2803528C2 (de) * 1977-03-09 1984-10-18 Tabushi, Iwao, Kyoto Schwermetallionen-Adsorbens und dessen Verwendung zum Adsorbieren von Schwermetallionen
JPS53144592A (en) * 1977-05-19 1978-12-15 Tabuse Iwao 122alkyll1*4*7*100tetrazacyclotridecane
US4432907A (en) * 1979-09-10 1984-02-21 Analytical Radiation Corporation Diamine acid fluorescent chelates
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
SU1098937A1 (ru) * 1983-03-25 1984-06-23 Ордена Ленина институт элементоорганических соединений им.А.Н.Несмеянова 1,4,7,10-Тетра/диоксифосфорилметил/-1,4,7,10-тетраазациклододекан в качестве комплексона дл св зывани катионов меди /п/,кобальта /п/,кадми /п/,свинца /п/ и лантана /ш/
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
US5342606A (en) * 1984-10-18 1994-08-30 Board Of Regents, The University Of Texas System Polyazamacrocyclic compounds for complexation of metal ions
DE3680924D1 (de) * 1985-01-14 1991-09-26 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
JPS61226751A (ja) * 1985-03-30 1986-10-08 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料用処理液及びその処理方法
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
DE3772785D1 (de) * 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.
FR2596992B1 (fr) * 1986-04-11 1988-12-16 Guerbet Sa Sel de lysine du complexe gadolinium-dota et ses applications au diagnostic
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate
US5049667A (en) * 1987-04-14 1991-09-17 Guerbet S.A. Nitrogen-containing cyclic ligands
DE3713842A1 (de) * 1987-04-22 1988-11-17 Schering Ag Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
GB8719042D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
CA2004798A1 (en) * 1988-12-09 1990-06-09 Jacques Banville 6-aminoalkyl carbapenems
GB8903023D0 (en) * 1989-02-10 1989-03-30 Parker David Chemical compounds
US5053503A (en) * 1989-02-17 1991-10-01 Centocor Chelating agents
AU654951B2 (en) * 1990-04-18 1994-12-01 Celltech Limited Tetra-aza macrocycles, processes for their preparation and their use in magnetic resonance imaging

Also Published As

Publication number Publication date
NO914979L (no) 1991-12-17
GB2250198A (en) 1992-06-03
EP0455380A2 (en) 1991-11-06
ATE147635T1 (de) 1997-02-15
GB2250198B (en) 1994-06-22
NZ237868A (en) 1994-04-27
US5653960A (en) 1997-08-05
IE911297A1 (en) 1991-10-23
AU7673091A (en) 1991-11-11
IL97902A0 (en) 1992-06-21
JPH05500969A (ja) 1993-02-25
IL97902A (en) 1996-03-31
GB9126303D0 (en) 1992-02-12
EP0455380A3 (en) 1991-11-27
CA2057868A1 (en) 1991-10-19
DE69124132D1 (de) 1997-02-27
FI915916A0 (fi) 1991-12-16
EP0455380B1 (en) 1997-01-15
AU654951B2 (en) 1994-12-01
DK0455380T3 (da) 1997-02-03
DE69124132T2 (de) 1997-06-05
WO1991016081A1 (en) 1991-10-31

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