FI915916A0 - Tetra-azamakrocykler, foerfaranden foer deras framstaellning och deras anvaendning vid magnetresonans- bildformning. - Google Patents

Tetra-azamakrocykler, foerfaranden foer deras framstaellning och deras anvaendning vid magnetresonans- bildformning.

Info

Publication number
FI915916A0
FI915916A0 FI915916A FI915916A FI915916A0 FI 915916 A0 FI915916 A0 FI 915916A0 FI 915916 A FI915916 A FI 915916A FI 915916 A FI915916 A FI 915916A FI 915916 A0 FI915916 A0 FI 915916A0
Authority
FI
Finland
Prior art keywords
group
alk
tetra
deras
hydrogen atom
Prior art date
Application number
FI915916A
Other languages
English (en)
Inventor
David Parker
Nigel Robert Arnold Beeley
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909008724A external-priority patent/GB9008724D0/en
Priority claimed from GB909008720A external-priority patent/GB9008720D0/en
Priority claimed from GB909017148A external-priority patent/GB9017148D0/en
Priority claimed from GB919104391A external-priority patent/GB9104391D0/en
Application filed by Celltech Ltd filed Critical Celltech Ltd
Publication of FI915916A0 publication Critical patent/FI915916A0/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/06Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6524Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI915916A 1990-04-18 1991-12-16 Tetra-azamakrocykler, foerfaranden foer deras framstaellning och deras anvaendning vid magnetresonans- bildformning. FI915916A0 (fi)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB909008724A GB9008724D0 (en) 1990-04-18 1990-04-18 Chemical compounds
GB909008720A GB9008720D0 (en) 1990-04-18 1990-04-18 Diagnostic agents
GB909017148A GB9017148D0 (en) 1990-08-03 1990-08-03 Diagnostic agents
GB919104391A GB9104391D0 (en) 1991-03-01 1991-03-01 Diagnostic agents
PCT/GB1991/000605 WO1991016081A1 (en) 1990-04-18 1991-04-18 Tetra-aza macrocycles, processes for their preparation and their use in magnetic resonance imaging

Publications (1)

Publication Number Publication Date
FI915916A0 true FI915916A0 (fi) 1991-12-16

Family

ID=27450496

Family Applications (1)

Application Number Title Priority Date Filing Date
FI915916A FI915916A0 (fi) 1990-04-18 1991-12-16 Tetra-azamakrocykler, foerfaranden foer deras framstaellning och deras anvaendning vid magnetresonans- bildformning.

Country Status (15)

Country Link
US (1) US5653960A (fi)
EP (1) EP0455380B1 (fi)
JP (1) JPH05500969A (fi)
AT (1) ATE147635T1 (fi)
AU (1) AU654951B2 (fi)
CA (1) CA2057868A1 (fi)
DE (1) DE69124132T2 (fi)
DK (1) DK0455380T3 (fi)
FI (1) FI915916A0 (fi)
GB (1) GB2250198B (fi)
IE (1) IE911297A1 (fi)
IL (1) IL97902A (fi)
NO (1) NO914979L (fi)
NZ (1) NZ237868A (fi)
WO (1) WO1991016081A1 (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342606A (en) * 1984-10-18 1994-08-30 Board Of Regents, The University Of Texas System Polyazamacrocyclic compounds for complexation of metal ions
NZ237868A (en) * 1990-04-18 1994-04-27 Celltech Ltd Paramagnetic metal complexes of 1,4,7,10-tetracyclododecane derivatives and their use as nmr imaging agents
US5409689A (en) * 1993-08-13 1995-04-25 Concat, Ltd. MRI image enhancement using complexes of paramagnetic cations and amine ligands containing a mixture of phosphonate and non-phosphonate pendant arms
TW319763B (fi) 1995-02-01 1997-11-11 Epix Medical Inc
EP0955044B1 (en) 1995-06-26 2005-11-16 Chelator LLC Method of inhibiting bacterial or fungal growth using a complexing agent
US5834456A (en) * 1996-02-23 1998-11-10 The Dow Chemical Company Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents
WO2000047111A1 (en) * 1999-02-09 2000-08-17 Board Of Regents The University Of Texas System Ph sensitive mri contrast agents
CA2371728C (en) 1999-06-11 2009-06-02 Neorx Corporation High dose radionuclide complexes for bone marrow suppression
US7094885B2 (en) 1999-07-11 2006-08-22 Neorx Corporation Skeletal-targeted radiation to treat bone-associated pathologies
AU1139302A (en) * 2000-09-29 2002-04-08 Anormed Inc Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
WO2002062398A2 (en) * 2001-01-08 2002-08-15 Neorx Corporation Radioactively labelled conjugates of phosphonates
EP1778699A4 (en) * 2004-08-10 2009-02-25 Dow Global Technologies Inc TARGETING OF CHELANTS AND CHELATES
WO2006045546A1 (en) * 2004-10-20 2006-05-04 Therapharm Gmbh Method of preparing or synthesizing polyazamacrocycle derivatives

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2803528C2 (de) * 1977-03-09 1984-10-18 Tabushi, Iwao, Kyoto Schwermetallionen-Adsorbens und dessen Verwendung zum Adsorbieren von Schwermetallionen
JPS53144592A (en) * 1977-05-19 1978-12-15 Tabuse Iwao 122alkyll1*4*7*100tetrazacyclotridecane
US4432907A (en) * 1979-09-10 1984-02-21 Analytical Radiation Corporation Diamine acid fluorescent chelates
US4671958A (en) * 1982-03-09 1987-06-09 Cytogen Corporation Antibody conjugates for the delivery of compounds to target sites
US4472509A (en) * 1982-06-07 1984-09-18 Gansow Otto A Metal chelate conjugated monoclonal antibodies
SU1098937A1 (ru) * 1983-03-25 1984-06-23 Ордена Ленина институт элементоорганических соединений им.А.Н.Несмеянова 1,4,7,10-Тетра/диоксифосфорилметил/-1,4,7,10-тетраазациклододекан в качестве комплексона дл св зывани катионов меди /п/,кобальта /п/,кадми /п/,свинца /п/ и лантана /ш/
CA1260827A (en) * 1984-08-31 1989-09-26 Richard C. Siegel Antibody-metal ion complexes
US4659839A (en) * 1984-10-10 1987-04-21 Mallinckrodt, Inc. Coupling agents for radiolabeled antibody fragments
US5342606A (en) * 1984-10-18 1994-08-30 Board Of Regents, The University Of Texas System Polyazamacrocyclic compounds for complexation of metal ions
ATE66469T1 (de) * 1985-01-14 1991-09-15 Neorx Corp Metall-radionuklid markiertes protein fuer diagnose und therapie.
JPS61226751A (ja) * 1985-03-30 1986-10-08 Konishiroku Photo Ind Co Ltd ハロゲン化銀写真感光材料用処理液及びその処理方法
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
US4885363A (en) * 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
DE3772785D1 (de) * 1986-01-23 1991-10-17 Squibb & Sons Inc 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga.
FR2596992B1 (fr) * 1986-04-11 1988-12-16 Guerbet Sa Sel de lysine du complexe gadolinium-dota et ses applications au diagnostic
DE3625417C2 (de) * 1986-07-28 1998-10-08 Schering Ag Tetraazacyclododecan-Derivate
US5049667A (en) * 1987-04-14 1991-09-17 Guerbet S.A. Nitrogen-containing cyclic ligands
DE3713842A1 (de) * 1987-04-22 1988-11-17 Schering Ag Substituierte cyclische komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel
GB8719042D0 (en) * 1987-08-12 1987-09-16 Parker D Conjugate compounds
CA2004798A1 (en) * 1988-12-09 1990-06-09 Jacques Banville 6-aminoalkyl carbapenems
GB8903023D0 (en) * 1989-02-10 1989-03-30 Parker David Chemical compounds
US5053503A (en) * 1989-02-17 1991-10-01 Centocor Chelating agents
NZ237868A (en) * 1990-04-18 1994-04-27 Celltech Ltd Paramagnetic metal complexes of 1,4,7,10-tetracyclododecane derivatives and their use as nmr imaging agents

Also Published As

Publication number Publication date
GB2250198A (en) 1992-06-03
CA2057868A1 (en) 1991-10-19
EP0455380B1 (en) 1997-01-15
GB9126303D0 (en) 1992-02-12
DE69124132T2 (de) 1997-06-05
DE69124132D1 (de) 1997-02-27
IE911297A1 (en) 1991-10-23
AU654951B2 (en) 1994-12-01
NO914979D0 (no) 1991-12-17
EP0455380A3 (en) 1991-11-27
DK0455380T3 (da) 1997-02-03
EP0455380A2 (en) 1991-11-06
NO914979L (no) 1991-12-17
JPH05500969A (ja) 1993-02-25
IL97902A (en) 1996-03-31
GB2250198B (en) 1994-06-22
IL97902A0 (en) 1992-06-21
AU7673091A (en) 1991-11-11
US5653960A (en) 1997-08-05
NZ237868A (en) 1994-04-27
WO1991016081A1 (en) 1991-10-31
ATE147635T1 (de) 1997-02-15

Similar Documents

Publication Publication Date Title
ATE288422T1 (de) Hepatobillianische magnetische resonanz- kontrastmittel
FI915916A0 (fi) Tetra-azamakrocykler, foerfaranden foer deras framstaellning och deras anvaendning vid magnetresonans- bildformning.
ES2086094T3 (es) Nuevas alquilamino-mercaptoalquilamidas o una de sus sales cosmeticamente aceptables, y su utilizacion como agentes reductores, en un procedimiento de deformacion permanente de los cabellos.
ES525680A0 (es) Procedimiento para la preparacion de derivados de amino acidos, de efecto edulcorante
ATE111342T1 (de) Färbemittel für keratinfasern.
BR8902086A (pt) Processo para preparacao de monopersulfatos de acido(poli)peroxicarboxilico derivados de amino
DE69324066D1 (de) 4-Phenylcarbamoyl-3-isoxazolecarbonsäure-Derivate mit entzündungshemmender Aktivität
DE69423339D1 (de) Epoxycyclohexendionderivat
ATE166205T1 (de) Tb-wirksame carbonsäure
BR9103951A (pt) Composicao anti-incrustante aquatica
FI900796A0 (fi) Aralkylaminfoereningar.
DE58902234D1 (de) Alpha-hydroxy-azolylethyloxirane und diese enthaltende fungizide.
DE69729565D1 (de) Neue pyridoncarbonsäure-derivate oder salze dieser derivate und antibakterielle mittel, die diese als aktiven wirkstoff enthalten
ATE120964T1 (de) Aza-makrozyklen enthaltende konjugate und verfahren zu deren herstellung.
JPS6420852A (en) Deodorant
GR81921B (fi)
TH14815A (th) สารฆ่าวัชพืชชนิดใหม่
TH11212EX (th) สารประกอบแคทไอออนิคและสารผสมสารทำความสะอาด

Legal Events

Date Code Title Description
FD Application lapsed