NO914734L - 5-amino-5,6,7,8-tetrahydrokinoliner og beslektede forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter - Google Patents

5-amino-5,6,7,8-tetrahydrokinoliner og beslektede forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter

Info

Publication number
NO914734L
NO914734L NO91914734A NO914734A NO914734L NO 914734 L NO914734 L NO 914734L NO 91914734 A NO91914734 A NO 91914734A NO 914734 A NO914734 A NO 914734A NO 914734 L NO914734 L NO 914734L
Authority
NO
Norway
Prior art keywords
arylalkyl
alkyl
formula
hydrogen
chem
Prior art date
Application number
NO91914734A
Other languages
English (en)
Norwegian (no)
Other versions
NO914734D0 (no
Inventor
Richard Charles Effland
David M Fink
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO914734D0 publication Critical patent/NO914734D0/no
Publication of NO914734L publication Critical patent/NO914734L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO91914734A 1990-12-03 1991-12-02 5-amino-5,6,7,8-tetrahydrokinoliner og beslektede forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter NO914734L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/620,811 US5110815A (en) 1990-12-03 1990-12-03 5-amino-5,6,7,8-tetrahydroquinolines and related compounds and pharmaceutical use

Publications (2)

Publication Number Publication Date
NO914734D0 NO914734D0 (no) 1991-12-02
NO914734L true NO914734L (no) 1992-06-04

Family

ID=24487491

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914734A NO914734L (no) 1990-12-03 1991-12-02 5-amino-5,6,7,8-tetrahydrokinoliner og beslektede forbindelser, fremgangsmaate for fremstilling og anvendelse som medikamenter

Country Status (17)

Country Link
US (2) US5110815A (de)
EP (1) EP0489379B1 (de)
JP (1) JP3090514B2 (de)
KR (1) KR100235506B1 (de)
AT (1) ATE168371T1 (de)
AU (1) AU639875B2 (de)
CA (1) CA2056793C (de)
DE (1) DE69129790T2 (de)
DK (1) DK0489379T3 (de)
ES (1) ES2119752T3 (de)
FI (1) FI915653A (de)
IE (1) IE914183A1 (de)
NO (1) NO914734L (de)
NZ (1) NZ240803A (de)
PT (1) PT99674B (de)
TW (1) TW211003B (de)
ZA (1) ZA919480B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL112568A0 (en) * 1994-02-10 1995-05-26 Wyeth John & Brother Ltd Substituted quinolines, their preparation and pharmaceutical compositions containing them
IL112566A (en) * 1994-02-10 2000-10-31 Wyeth John & Brother Ltd Substituted quinolinones and pharmaceutical compositions containing them
IL112567A (en) * 1994-02-10 2000-02-29 Wyeth John & Brother Ltd Substituted quinolines their preparation and pharmaceutical compositions containing them
KR0158065B1 (ko) * 1995-05-29 1998-12-01 스기야마 가즈히코 반도체 집적회로장치 및 그 제조방법
KR100639543B1 (ko) 1998-09-30 2006-10-31 다케다 야쿠힌 고교 가부시키가이샤 방광 배출력 개선제
TWI301760B (en) * 2004-02-27 2008-10-11 Merz Pharma Gmbh & Co Kgaa Tetrahydroquinolinones and their use as antagonists of metabotropic glutamate receptors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4789678A (en) * 1986-08-25 1988-12-06 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing α-alkyl-4-amino-3-quinolinemethanols and 1-(4-aralkylamino-3-quinolinyl)alkanones and related compounds
US4942168A (en) * 1987-07-13 1990-07-17 Hoechst-Roussel Pharmaceuticals Inc. Hydroxyquinoline amines, and method of enhancing memory in mammals
EP0361489A3 (de) * 1988-09-30 1991-06-12 Chugai Seiyaku Kabushiki Kaisha 3,4-Diaminochinolin- und Pyridinverbindungen
JPH0322011A (ja) * 1989-06-19 1991-01-30 Nec Corp キーボード入力データ処理方式

Also Published As

Publication number Publication date
DE69129790T2 (de) 1999-05-06
IE914183A1 (en) 1992-06-03
NZ240803A (en) 1994-07-26
ES2119752T3 (es) 1998-10-16
KR100235506B1 (ko) 1999-12-15
PT99674B (pt) 1999-05-31
US5310914A (en) 1994-05-10
FI915653A (fi) 1992-06-04
AU639875B2 (en) 1993-08-05
PT99674A (pt) 1992-10-30
JPH04290872A (ja) 1992-10-15
EP0489379A1 (de) 1992-06-10
DE69129790D1 (de) 1998-08-20
AU8835291A (en) 1992-06-04
ATE168371T1 (de) 1998-08-15
FI915653A0 (fi) 1991-11-29
ZA919480B (en) 1992-08-26
DK0489379T3 (da) 1999-04-19
JP3090514B2 (ja) 2000-09-25
NO914734D0 (no) 1991-12-02
US5110815A (en) 1992-05-05
CA2056793A1 (en) 1992-06-04
CA2056793C (en) 2003-03-11
EP0489379B1 (de) 1998-07-15
KR920012036A (ko) 1992-07-25
TW211003B (de) 1993-08-11

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