NO914720L - Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner - Google Patents
Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjonerInfo
- Publication number
- NO914720L NO914720L NO91914720A NO914720A NO914720L NO 914720 L NO914720 L NO 914720L NO 91914720 A NO91914720 A NO 91914720A NO 914720 A NO914720 A NO 914720A NO 914720 L NO914720 L NO 914720L
- Authority
- NO
- Norway
- Prior art keywords
- alfa
- spiral
- changes
- area
- combinations
- Prior art date
Links
- 230000035772 mutation Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 102000018997 Growth Hormone Human genes 0.000 abstract 1
- 108010051696 Growth Hormone Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000002741 site-directed mutagenesis Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/12—Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Analytical Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/621,197 US5310882A (en) | 1990-11-30 | 1990-11-30 | Somatotropins with alterations in the α-helix 3 region |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO914720D0 NO914720D0 (no) | 1991-11-29 |
| NO914720L true NO914720L (no) | 1992-06-01 |
Family
ID=24489157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO91914720A NO914720L (no) | 1990-11-30 | 1991-11-29 | Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5310882A (ja) |
| EP (1) | EP0488279A3 (ja) |
| JP (1) | JPH0570497A (ja) |
| KR (1) | KR920009414A (ja) |
| AU (1) | AU662492B2 (ja) |
| CA (1) | CA2056564A1 (ja) |
| FI (1) | FI915655A (ja) |
| HU (1) | HUT62328A (ja) |
| IE (1) | IE914154A1 (ja) |
| IL (1) | IL100170A0 (ja) |
| NO (1) | NO914720L (ja) |
| NZ (1) | NZ240720A (ja) |
| PT (1) | PT99647A (ja) |
| TW (1) | TW205045B (ja) |
| ZA (1) | ZA919452B (ja) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4805393A (en) * | 1992-08-07 | 1994-03-03 | Pitman-Moore, Inc. | Improving the body composition of fish via the administration of porcine somatotropin (pst) |
| ZA936811B (en) * | 1992-10-28 | 1995-03-15 | Upjohn Co | Somatotropin modifications |
| WO2002026967A2 (en) * | 2000-09-25 | 2002-04-04 | Thomas Jefferson University | Targeted gene correction by single-stranded oligodeoxynucleotides |
| WO2004022593A2 (en) * | 2002-09-09 | 2004-03-18 | Nautilus Biotech | Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules |
| US7998930B2 (en) | 2004-11-04 | 2011-08-16 | Hanall Biopharma Co., Ltd. | Modified growth hormones |
| US7772162B2 (en) * | 2006-03-27 | 2010-08-10 | Board Of Regents, The University Of Texas System | Use of fluorocarbon surfactants to improve the productivity of gas and gas condensate wells |
| US20070225176A1 (en) * | 2006-03-27 | 2007-09-27 | Pope Gary A | Use of fluorocarbon surfactants to improve the productivity of gas and gas condensate wells |
| US20080047706A1 (en) * | 2006-08-23 | 2008-02-28 | Pope Gary A | Method of obtaining a treatment composition for improving the productivity of hydrocarbon producing wells |
| EP2137280A4 (en) * | 2007-03-23 | 2010-09-08 | Univ Texas | METHOD FOR TREATING A FRACTURED FORMATION |
| EP2132240A4 (en) * | 2007-03-23 | 2010-03-10 | Univ Texas | COMPOSITIONS AND METHOD FOR TREATING A WATER BLOCKED DRILL OXIDE |
| MX2009010142A (es) * | 2007-03-23 | 2010-03-22 | Univ Texas | Composiciones y metodos para tratar un pozo de agua bloqueado. |
| RU2009136515A (ru) * | 2007-03-23 | 2011-04-27 | Борд Оф Риджентс, Зе Юниверсити Оф Техас Систем (Us) | Способ и система для обработки углеводородных формаций |
| CN107056929A (zh) * | 2009-12-21 | 2017-08-18 | Ambrx 公司 | 经过修饰的猪促生长素多肽和其用途 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68929273T2 (de) * | 1988-08-24 | 2001-07-05 | American Cyanamid Co., Wayne | Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung |
| WO1990004788A1 (en) * | 1988-10-28 | 1990-05-03 | Genentech, Inc. | Method for identifying active domains and amino acid residues in polypeptides and hormone variants |
| EP0482124B1 (en) * | 1989-07-10 | 1993-12-22 | The Upjohn Company | Somatotropin analogs |
| WO1991005853A1 (en) * | 1989-10-12 | 1991-05-02 | Ohio University | Growth hormone antagonists |
-
1990
- 1990-11-30 US US07/621,197 patent/US5310882A/en not_active Expired - Fee Related
-
1991
- 1991-11-25 NZ NZ240720A patent/NZ240720A/en unknown
- 1991-11-27 IL IL100170A patent/IL100170A0/xx unknown
- 1991-11-28 EP EP19910120390 patent/EP0488279A3/en not_active Withdrawn
- 1991-11-28 CA CA002056564A patent/CA2056564A1/en not_active Abandoned
- 1991-11-29 FI FI915655A patent/FI915655A/fi not_active Application Discontinuation
- 1991-11-29 HU HU913724A patent/HUT62328A/hu unknown
- 1991-11-29 AU AU88293/91A patent/AU662492B2/en not_active Expired - Fee Related
- 1991-11-29 IE IE415491A patent/IE914154A1/en not_active Application Discontinuation
- 1991-11-29 NO NO91914720A patent/NO914720L/no unknown
- 1991-11-29 PT PT99647A patent/PT99647A/pt not_active Application Discontinuation
- 1991-11-29 JP JP3339492A patent/JPH0570497A/ja active Pending
- 1991-11-29 ZA ZA919452A patent/ZA919452B/xx unknown
- 1991-11-29 TW TW080109400A patent/TW205045B/zh active
- 1991-11-30 KR KR1019910021902A patent/KR920009414A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT99647A (pt) | 1992-10-30 |
| US5310882A (en) | 1994-05-10 |
| HUT62328A (en) | 1993-04-28 |
| ZA919452B (en) | 1992-08-26 |
| EP0488279A2 (en) | 1992-06-03 |
| TW205045B (ja) | 1993-05-01 |
| FI915655A (fi) | 1992-05-31 |
| IE914154A1 (en) | 1992-06-03 |
| EP0488279A3 (en) | 1993-02-24 |
| IL100170A0 (en) | 1992-08-18 |
| NO914720D0 (no) | 1991-11-29 |
| NZ240720A (en) | 1995-07-26 |
| JPH0570497A (ja) | 1993-03-23 |
| FI915655A0 (fi) | 1991-11-29 |
| CA2056564A1 (en) | 1992-05-31 |
| HU913724D0 (en) | 1992-02-28 |
| AU8829391A (en) | 1992-06-04 |
| AU662492B2 (en) | 1995-09-07 |
| KR920009414A (ko) | 1992-06-25 |
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