NO914720L - Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner - Google Patents

Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner

Info

Publication number
NO914720L
NO914720L NO91914720A NO914720A NO914720L NO 914720 L NO914720 L NO 914720L NO 91914720 A NO91914720 A NO 91914720A NO 914720 A NO914720 A NO 914720A NO 914720 L NO914720 L NO 914720L
Authority
NO
Norway
Prior art keywords
alfa
spiral
changes
area
combinations
Prior art date
Application number
NO91914720A
Other languages
English (en)
Norwegian (no)
Other versions
NO914720D0 (no
Inventor
Deborah Tardy Chaleff
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NO914720D0 publication Critical patent/NO914720D0/no
Publication of NO914720L publication Critical patent/NO914720L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102Mutagenizing nucleic acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/12Growth hormone, growth factor other than t-cell or b-cell growth factor, and growth hormone releasing factor; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO91914720A 1990-11-30 1991-11-29 Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner NO914720L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/621,197 US5310882A (en) 1990-11-30 1990-11-30 Somatotropins with alterations in the α-helix 3 region

Publications (2)

Publication Number Publication Date
NO914720D0 NO914720D0 (no) 1991-11-29
NO914720L true NO914720L (no) 1992-06-01

Family

ID=24489157

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914720A NO914720L (no) 1990-11-30 1991-11-29 Somatotropiner med forandringer i alfa-spiral-3-omraadet, alfa-spiral-2-omraadekombinasjoner derav og i kombinasjon medandre mutasjoner

Country Status (15)

Country Link
US (1) US5310882A (ja)
EP (1) EP0488279A3 (ja)
JP (1) JPH0570497A (ja)
KR (1) KR920009414A (ja)
AU (1) AU662492B2 (ja)
CA (1) CA2056564A1 (ja)
FI (1) FI915655A (ja)
HU (1) HUT62328A (ja)
IE (1) IE914154A1 (ja)
IL (1) IL100170A0 (ja)
NO (1) NO914720L (ja)
NZ (1) NZ240720A (ja)
PT (1) PT99647A (ja)
TW (1) TW205045B (ja)
ZA (1) ZA919452B (ja)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4805393A (en) * 1992-08-07 1994-03-03 Pitman-Moore, Inc. Improving the body composition of fish via the administration of porcine somatotropin (pst)
ZA936811B (en) * 1992-10-28 1995-03-15 Upjohn Co Somatotropin modifications
WO2002026967A2 (en) * 2000-09-25 2002-04-04 Thomas Jefferson University Targeted gene correction by single-stranded oligodeoxynucleotides
WO2004022593A2 (en) * 2002-09-09 2004-03-18 Nautilus Biotech Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules
US7998930B2 (en) 2004-11-04 2011-08-16 Hanall Biopharma Co., Ltd. Modified growth hormones
US7772162B2 (en) * 2006-03-27 2010-08-10 Board Of Regents, The University Of Texas System Use of fluorocarbon surfactants to improve the productivity of gas and gas condensate wells
US20070225176A1 (en) * 2006-03-27 2007-09-27 Pope Gary A Use of fluorocarbon surfactants to improve the productivity of gas and gas condensate wells
US20080047706A1 (en) * 2006-08-23 2008-02-28 Pope Gary A Method of obtaining a treatment composition for improving the productivity of hydrocarbon producing wells
EP2137280A4 (en) * 2007-03-23 2010-09-08 Univ Texas METHOD FOR TREATING A FRACTURED FORMATION
EP2132240A4 (en) * 2007-03-23 2010-03-10 Univ Texas COMPOSITIONS AND METHOD FOR TREATING A WATER BLOCKED DRILL OXIDE
MX2009010142A (es) * 2007-03-23 2010-03-22 Univ Texas Composiciones y metodos para tratar un pozo de agua bloqueado.
RU2009136515A (ru) * 2007-03-23 2011-04-27 Борд Оф Риджентс, Зе Юниверсити Оф Техас Систем (Us) Способ и система для обработки углеводородных формаций
CN107056929A (zh) * 2009-12-21 2017-08-18 Ambrx 公司 经过修饰的猪促生长素多肽和其用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68929273T2 (de) * 1988-08-24 2001-07-05 American Cyanamid Co., Wayne Stabilisierung von Somatotropinen durch Modifikation von Cystein-Resten durch orts-spezifische Mutagenese oder chemische Derivatisierung
WO1990004788A1 (en) * 1988-10-28 1990-05-03 Genentech, Inc. Method for identifying active domains and amino acid residues in polypeptides and hormone variants
EP0482124B1 (en) * 1989-07-10 1993-12-22 The Upjohn Company Somatotropin analogs
WO1991005853A1 (en) * 1989-10-12 1991-05-02 Ohio University Growth hormone antagonists

Also Published As

Publication number Publication date
PT99647A (pt) 1992-10-30
US5310882A (en) 1994-05-10
HUT62328A (en) 1993-04-28
ZA919452B (en) 1992-08-26
EP0488279A2 (en) 1992-06-03
TW205045B (ja) 1993-05-01
FI915655A (fi) 1992-05-31
IE914154A1 (en) 1992-06-03
EP0488279A3 (en) 1993-02-24
IL100170A0 (en) 1992-08-18
NO914720D0 (no) 1991-11-29
NZ240720A (en) 1995-07-26
JPH0570497A (ja) 1993-03-23
FI915655A0 (fi) 1991-11-29
CA2056564A1 (en) 1992-05-31
HU913724D0 (en) 1992-02-28
AU8829391A (en) 1992-06-04
AU662492B2 (en) 1995-09-07
KR920009414A (ko) 1992-06-25

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