NO913518D0 - Vaksiner for ikke typebestembar haemophilus influenzae. - Google Patents
Vaksiner for ikke typebestembar haemophilus influenzae.Info
- Publication number
- NO913518D0 NO913518D0 NO913518A NO913518A NO913518D0 NO 913518 D0 NO913518 D0 NO 913518D0 NO 913518 A NO913518 A NO 913518A NO 913518 A NO913518 A NO 913518A NO 913518 D0 NO913518 D0 NO 913518D0
- Authority
- NO
- Norway
- Prior art keywords
- testable
- vaccines
- type
- extracting
- haemophilus influenzae
- Prior art date
Links
- 241000606768 Haemophilus influenzae Species 0.000 title abstract 3
- 229940047650 haemophilus influenzae Drugs 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 239000007864 aqueous solution Substances 0.000 abstract 2
- IZWSFJTYBVKZNK-UHFFFAOYSA-N lauryl sulfobetaine Chemical compound CCCCCCCCCCCC[N+](C)(C)CCCS([O-])(=O)=O IZWSFJTYBVKZNK-UHFFFAOYSA-N 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- KSAVQLQVUXSOCR-UHFFFAOYSA-M sodium lauroyl sarcosinate Chemical compound [Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O KSAVQLQVUXSOCR-UHFFFAOYSA-M 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1242—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32097189A | 1989-03-09 | 1989-03-09 | |
PCT/US1990/001317 WO1990010458A1 (en) | 1989-03-09 | 1990-03-09 | Vaccines for nontypable haemophilus influenzae |
Publications (2)
Publication Number | Publication Date |
---|---|
NO913518D0 true NO913518D0 (no) | 1991-09-06 |
NO913518L NO913518L (no) | 1991-10-29 |
Family
ID=23248627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO91913518A NO913518L (no) | 1989-03-09 | 1991-09-06 | Vaksiner for ikke typebestembar haemophilus influenzae. |
Country Status (13)
Country | Link |
---|---|
US (4) | US5601831A (no) |
EP (2) | EP0606921B1 (no) |
JP (1) | JP2955014B2 (no) |
KR (1) | KR100188323B1 (no) |
AT (2) | ATE110965T1 (no) |
AU (1) | AU648251B2 (no) |
CA (1) | CA2047681C (no) |
DE (2) | DE69012318T2 (no) |
DK (2) | DK0462210T3 (no) |
ES (2) | ES2150450T3 (no) |
FI (1) | FI914241A0 (no) |
NO (1) | NO913518L (no) |
WO (1) | WO1990010458A1 (no) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1340888C (en) * | 1988-09-01 | 2000-02-01 | Algis Anilionis | Vaccines and diagnostic assays for haemophilus influenzae |
AU2699192A (en) * | 1991-10-16 | 1993-05-21 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
US5422110A (en) * | 1991-10-16 | 1995-06-06 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
US6797272B1 (en) | 1991-10-16 | 2004-09-28 | University Of Saskatchewan | Enhanced immunogenicity using leukotoxin chimeras |
ATE190502T1 (de) * | 1993-05-13 | 2000-04-15 | American Cyanamid Co | Herstellung und verwendungen von los-verminderten aussenmembran-proteinen von gram-negativen kokken |
US5681570A (en) * | 1995-01-12 | 1997-10-28 | Connaught Laboratories Limited | Immunogenic conjugate molecules |
US20020032316A1 (en) * | 1995-03-31 | 2002-03-14 | Cantab Pharmaceuticals Research Limited | Hapten-carrier conjugates for use in drug-abuse therapy and methods for preparation of same |
AU716806B2 (en) * | 1995-04-17 | 2000-03-09 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Induction and enhancement of the immune response to polysaccharides with bacterial lipoproteins |
AR003125A1 (es) * | 1995-06-01 | 1998-07-08 | Astra Ab | Antigenos bacterianos para el diagnostico de infecciones con helicobacter pylori, una molecula de adn que lo codifica, un vector, una celula huesped,procedimiento para producir el polipeptido, composiciones para vacunas adecuadas para uso terapeutico y profilactico, el uso del polipeptido en la |
GB9513074D0 (en) * | 1995-06-27 | 1995-08-30 | Cortecs Ltd | Novel anigen |
US6207157B1 (en) * | 1996-04-23 | 2001-03-27 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for nontypeable Haemophilus influenzae |
US20040126381A1 (en) * | 1996-04-23 | 2004-07-01 | Xin-Xing Gu | Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella |
ZA9810122B (en) * | 1997-11-12 | 1999-05-12 | Hoffmann La Roche | Treatment of T-helper cell type 2 mediated immune diseases |
US6255050B1 (en) * | 1998-05-22 | 2001-07-03 | Lorne Park Research, Inc. | Dynamic hybridization system |
CA2370694C (en) * | 1999-06-25 | 2010-02-09 | American Cyanamid Company | Extraction of integral membrane proteins |
US7101989B1 (en) | 1999-07-09 | 2006-09-05 | University Of North Carolina At Chapel Hill | DsrA protein and polynucleotides encoding the same |
US6391313B1 (en) * | 1999-07-15 | 2002-05-21 | Aventis Pasteur Limited | Multi-component vaccine to protect against disease caused by Haemophilus influenzae and Moraxella catarrhalis |
EP1210114A4 (en) * | 1999-08-20 | 2004-01-02 | Gen Hospital Corp | OUTER MEMBRANE PROTEIN A, PEPTIDOGLYCAN ASSOCIATED LIPOPROTEIN AND MUREINLIPOPROTEIN AS THERAPEUTIC OBJECTIVES FOR THE TREATMENT OF SEPSIS |
US7384640B1 (en) * | 1999-09-30 | 2008-06-10 | Wyeth Holdings Corporation | Mutant cholera holotoxin as an adjuvant |
AU8640501A (en) * | 2000-07-31 | 2002-02-13 | Univ Yale | Innate immune system-directed vaccines |
US20030232055A1 (en) * | 2000-07-31 | 2003-12-18 | Ruslan Medzhitov | Innate immune system-directed vaccines |
GB0025486D0 (en) * | 2000-10-17 | 2000-11-29 | Smithkline Beecham Biolog | Novel compounds |
US20030175287A1 (en) * | 2001-01-03 | 2003-09-18 | Yale University | Innate immune system-directed vaccines |
AT410798B (de) * | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
US6834384B2 (en) * | 2001-03-14 | 2004-12-21 | General Instrument Corporation | Methods and apparatus for upgrading firmware in an embedded system |
CA2446355A1 (en) * | 2001-05-03 | 2002-11-14 | The Government Of The United States Of America | Intranasal immunization with detoxified lipooligosaccharide from nontypeable haemophilus influenzae or moraxella catarrhalis |
JP2005508143A (ja) * | 2001-06-07 | 2005-03-31 | ワイス・ホールデイングス・コーポレーシヨン | アジュバントとしてのコレラホロトキシンの突然変異形 |
US7285281B2 (en) | 2001-06-07 | 2007-10-23 | Wyeth Holdings Corporation | Mutant forms of cholera holotoxin as an adjuvant |
AU2002310760A1 (en) * | 2001-06-12 | 2002-12-23 | Glaxosmithkline Biologicals S.A. | Proteins derived from non-typable haemophilus influenzae (nthi) strain |
GB0117762D0 (en) * | 2001-07-20 | 2001-09-12 | Glaxosmithkline Biolog Sa | Novel compounds |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
CA2479118A1 (en) * | 2002-03-15 | 2003-09-25 | Wyeth Holdings Corporation | Mutants of the p4 protein of nontypable haemophilus influenzae with reduced enzymatic activity |
US8420102B2 (en) | 2006-03-07 | 2013-04-16 | Vaxinnate Corporation | Compositions that include hemagglutinin |
CN101180079B (zh) | 2005-04-08 | 2012-07-18 | 惠氏公司 | 多价肺炎球菌多糖-蛋白质缀合物组合物 |
US7709001B2 (en) | 2005-04-08 | 2010-05-04 | Wyeth Llc | Multivalent pneumococcal polysaccharide-protein conjugate composition |
KR20070047455A (ko) * | 2005-11-02 | 2007-05-07 | 삼성에스디아이 주식회사 | 전자 방출 표시 디바이스 |
ES2557160T3 (es) * | 2006-10-23 | 2016-01-22 | Nestec S.A. | Modulación del aroma y el sabor mediante biotransformación en productos lácteos |
AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
KR20110111381A (ko) * | 2009-01-07 | 2011-10-11 | 오츠카 세이야쿠 가부시키가이샤 | 전 인플루엔자균의 측정방법 |
MX350142B (es) | 2010-08-23 | 2017-08-28 | Wyeth Llc * | Formulaciones estables de antigenos rlp2086 de neisseria meningitidis. |
EP3549601B1 (en) | 2010-09-10 | 2021-02-24 | Wyeth LLC | Non-lipidated variants of neisseria meningitidis orf2086 antigens |
TW201302779A (zh) * | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
MX359256B (es) | 2012-03-09 | 2018-09-19 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
EP2964665B1 (en) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Immunogenic fusion polypeptides |
RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
CN107249626A (zh) | 2015-02-19 | 2017-10-13 | 辉瑞大药厂 | 脑膜炎奈瑟球菌组合物及其方法 |
SG11201906519RA (en) | 2017-01-31 | 2019-08-27 | Pfizer | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4220717A (en) * | 1977-12-22 | 1980-09-02 | American Cyanamid Company | Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b. |
US4220722A (en) * | 1978-02-10 | 1980-09-02 | Syva Company | Method for conjugating to polyamino compounds employing haloacyl groups and compositions prepared thereby |
US4356170A (en) * | 1981-05-27 | 1982-10-26 | Canadian Patents & Development Ltd. | Immunogenic polysaccharide-protein conjugates |
US4496538A (en) * | 1982-07-06 | 1985-01-29 | Connaught Laboratories, Inc. | Haemophilus influenzae b polysaccharide-diphtheria toxoid conjugate vaccine |
US4661347A (en) * | 1982-11-12 | 1987-04-28 | Scripps Clinic | Cytotoxic compositions |
US4762713A (en) * | 1983-07-05 | 1988-08-09 | The University Of Rochester | Boosting of immunogenic conjugate vaccinations by unconjugated bacterial capsular polymers |
NZ214503A (en) * | 1984-12-20 | 1990-02-26 | Merck & Co Inc | Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates |
US4873090A (en) * | 1985-03-27 | 1989-10-10 | Broncostat Pty. Limited | Non-adjuvenated vaccine |
US4707543A (en) * | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
JP2534529B2 (ja) * | 1986-07-24 | 1996-09-18 | ブリティシュ・テレコミュニケ−ションズ・パブリック・リミテッド・カンパニ | 放射発生器 |
US5173294A (en) * | 1986-11-18 | 1992-12-22 | Research Foundation Of State University Of New York | Dna probe for the identification of haemophilus influenzae |
AU623353B2 (en) * | 1987-12-10 | 1992-05-14 | Board Of Regents, The University Of Texas System | Methods and compositions for the production of haemophilus influenzae type b major outer membrane protein antigens |
-
1990
- 1990-03-09 AU AU53326/90A patent/AU648251B2/en not_active Expired
- 1990-03-09 CA CA002047681A patent/CA2047681C/en not_active Expired - Lifetime
- 1990-03-09 DE DE69012318T patent/DE69012318T2/de not_active Expired - Lifetime
- 1990-03-09 US US07/491,466 patent/US5601831A/en not_active Expired - Lifetime
- 1990-03-09 JP JP2505084A patent/JP2955014B2/ja not_active Expired - Lifetime
- 1990-03-09 EP EP94100492A patent/EP0606921B1/en not_active Expired - Lifetime
- 1990-03-09 DE DE69033600T patent/DE69033600T2/de not_active Expired - Lifetime
- 1990-03-09 ES ES94100492T patent/ES2150450T3/es not_active Expired - Lifetime
- 1990-03-09 DK DK90905112.0T patent/DK0462210T3/da active
- 1990-03-09 AT AT90905112T patent/ATE110965T1/de not_active IP Right Cessation
- 1990-03-09 AT AT94100492T patent/ATE195076T1/de not_active IP Right Cessation
- 1990-03-09 WO PCT/US1990/001317 patent/WO1990010458A1/en active IP Right Grant
- 1990-03-09 DK DK94100492T patent/DK0606921T3/da active
- 1990-03-09 KR KR1019910701102A patent/KR100188323B1/ko not_active IP Right Cessation
- 1990-03-09 ES ES90905112T patent/ES2063965T3/es not_active Expired - Lifetime
- 1990-03-09 EP EP90905112A patent/EP0462210B1/en not_active Expired - Lifetime
-
1991
- 1991-09-06 NO NO91913518A patent/NO913518L/no unknown
- 1991-09-09 FI FI914241A patent/FI914241A0/fi not_active Application Discontinuation
-
1995
- 1995-05-23 US US08/447,653 patent/US5780601A/en not_active Expired - Lifetime
- 1995-05-23 US US08/448,097 patent/US6420134B1/en not_active Expired - Fee Related
- 1995-05-23 US US08/449,406 patent/US5955580A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6420134B1 (en) | 2002-07-16 |
US5780601A (en) | 1998-07-14 |
DE69012318D1 (de) | 1994-10-13 |
EP0606921B1 (en) | 2000-08-02 |
US5601831A (en) | 1997-02-11 |
ES2063965T3 (es) | 1995-01-16 |
DE69033600T2 (de) | 2001-04-05 |
CA2047681C (en) | 2000-02-01 |
DK0462210T3 (da) | 1994-10-10 |
JP2955014B2 (ja) | 1999-10-04 |
CA2047681A1 (en) | 1990-09-10 |
ATE110965T1 (de) | 1994-09-15 |
US5955580A (en) | 1999-09-21 |
KR100188323B1 (ko) | 1999-06-01 |
EP0606921A1 (en) | 1994-07-20 |
EP0462210A1 (en) | 1991-12-27 |
DK0606921T3 (da) | 2000-09-04 |
WO1990010458A1 (en) | 1990-09-20 |
FI914241A0 (fi) | 1991-09-09 |
DE69012318T2 (de) | 1995-03-09 |
AU648251B2 (en) | 1994-04-21 |
ATE195076T1 (de) | 2000-08-15 |
DE69033600D1 (de) | 2000-09-07 |
EP0462210B1 (en) | 1994-09-07 |
AU5332690A (en) | 1990-10-09 |
JPH07508972A (ja) | 1995-10-05 |
NO913518L (no) | 1991-10-29 |
ES2150450T3 (es) | 2000-12-01 |
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