NO913188L - Fremgangsmaate ved fremstilling av enantiomert rene polysubstituerte 1,4-dihydropyridiner. - Google Patents
Fremgangsmaate ved fremstilling av enantiomert rene polysubstituerte 1,4-dihydropyridiner.Info
- Publication number
- NO913188L NO913188L NO91913188A NO913188A NO913188L NO 913188 L NO913188 L NO 913188L NO 91913188 A NO91913188 A NO 91913188A NO 913188 A NO913188 A NO 913188A NO 913188 L NO913188 L NO 913188L
- Authority
- NO
- Norway
- Prior art keywords
- dihydropyridines
- enantiomerally
- pure
- substituted
- procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8919477A IT1230752B (it) | 1989-02-17 | 1989-02-17 | Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura. |
PCT/EP1990/000243 WO1990009376A1 (en) | 1989-02-17 | 1990-02-15 | A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines |
Publications (4)
Publication Number | Publication Date |
---|---|
NO913188D0 NO913188D0 (no) | 1991-08-15 |
NO913188L true NO913188L (no) | 1991-08-15 |
NO177186B NO177186B (no) | 1995-04-24 |
NO177186C NO177186C (no) | 1995-08-02 |
Family
ID=11158352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO913188A NO177186C (no) | 1989-02-17 | 1991-08-15 | Fremgangsmåte ved fremstilling av enantiomert rene polysubstituerte 1,4-dihydropyridiner |
Country Status (17)
Country | Link |
---|---|
US (1) | US5245039A (no) |
EP (2) | EP0383320A1 (no) |
JP (1) | JPH04505610A (no) |
KR (1) | KR0155557B1 (no) |
AT (1) | ATE95813T1 (no) |
AU (1) | AU630928B2 (no) |
CA (1) | CA2047741A1 (no) |
DE (1) | DE69003936T2 (no) |
DK (1) | DK0458823T3 (no) |
ES (1) | ES2060144T3 (no) |
FI (1) | FI95371C (no) |
HU (1) | HUT62270A (no) |
IE (1) | IE66498B1 (no) |
IT (1) | IT1230752B (no) |
NO (1) | NO177186C (no) |
RU (1) | RU2069658C1 (no) |
WO (1) | WO1990009376A1 (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5571827A (en) * | 1990-03-13 | 1996-11-05 | Sepracor Inc. | Methods and compositions for treating hypertension, angina and other disorders using optically pure s(-) nitrendipine |
EP0661971A1 (en) * | 1991-12-02 | 1995-07-12 | Sepracor, Inc. | Methods and compositions for treating hypertension, angina, and other disorders using optically pure s(-) felodipine |
US5834496A (en) * | 1991-12-02 | 1998-11-10 | Sepracor, Inc. | Methods for treating hypertension using optically pure S(-) felodipine |
ES2055652B1 (es) * | 1992-09-22 | 1995-03-01 | Elmuquimica Farm Sl | Procedimiento de obtencion de 2,6-dimetil-4-(2,3-diclorofenil)-1,4-dihidropiridin-3,5-dicarboxilato de 3-etil-5-metil. |
ES2055654B1 (es) * | 1992-09-22 | 1995-03-01 | Elmuquimica Farm Sl | Procedimiento de obtencion de 2,6-dimetil-4-(3-nitrofenil)-1,4-dihidropiridin-3,5-dicarboxilato de 3-etil-5-metil. |
ES2055653B1 (es) * | 1992-09-22 | 1995-03-01 | Elmuquimica Farm Sl | Procedimiento de obtencion del 2,6-dimetil-4-(3-nitrofenil)-1,4-dihidropiridin-3,5-dicarboxilato de 3-isopropil-5-(2-metoxi)etil. |
ES2055655B1 (es) * | 1992-09-22 | 1995-03-01 | Elmuquimica Farm Sl | Procedimiento de obtencion de 2,6-dimetil-4-(2-nitrofenil)-1,4-dihidropiridin-3,5-dicarboxilato de 3-isobutil-5-metil. |
GB9405833D0 (en) * | 1994-03-24 | 1994-05-11 | Pfizer Ltd | Separation of the enantiomers of amlodipine |
FR2719585B1 (fr) * | 1994-05-05 | 1996-08-02 | Lafon Labor | Procédé d'obtention de 1,4-dihydropyridines optiquement pures. |
US5554621A (en) * | 1995-06-07 | 1996-09-10 | Bristol-Myers Squibb Company | Dihydropyridine NPY antagonists: nitrogen heterocyclic derivatives |
ITMI20012434A1 (it) | 2001-11-20 | 2003-05-20 | Dompe Spa | Acidi 2-aril-propionici e composizioni farmaceutiche che li contengono |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3447169A1 (de) * | 1984-12-22 | 1986-07-03 | Bayer Ag, 5090 Leverkusen | Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
EP0233228A1 (en) * | 1985-08-06 | 1987-08-26 | Boehringer Mannheim Italia S.P.A. | Pharmaceutically active 2-thiomethyl-substituted-1,4-dihydropyridines |
EP0225175A3 (en) * | 1985-11-28 | 1988-12-28 | FISONS plc | Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof |
US4920225A (en) * | 1986-12-22 | 1990-04-24 | Laboratoires Syntex S.A. | Resolution of 1,4-dihydropyridine derivatives |
WO1988007525A1 (en) * | 1987-03-27 | 1988-10-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh | 1,4-dihydropyridine enantiomers |
WO1988007531A1 (en) * | 1987-03-27 | 1988-10-06 | Byk Gulden Lomberg Chemische Fabrik Gmbh | New optically active compounds |
-
1989
- 1989-02-17 IT IT8919477A patent/IT1230752B/it active
-
1990
- 1990-02-15 EP EP90102951A patent/EP0383320A1/en not_active Withdrawn
- 1990-02-15 ES ES90903015T patent/ES2060144T3/es not_active Expired - Lifetime
- 1990-02-15 AT AT90903015T patent/ATE95813T1/de not_active IP Right Cessation
- 1990-02-15 EP EP90903015A patent/EP0458823B1/en not_active Expired - Lifetime
- 1990-02-15 AU AU50904/90A patent/AU630928B2/en not_active Ceased
- 1990-02-15 HU HU901962A patent/HUT62270A/hu unknown
- 1990-02-15 CA CA002047741A patent/CA2047741A1/en not_active Abandoned
- 1990-02-15 DK DK90903015.7T patent/DK0458823T3/da active
- 1990-02-15 JP JP2503175A patent/JPH04505610A/ja active Pending
- 1990-02-15 WO PCT/EP1990/000243 patent/WO1990009376A1/en active IP Right Grant
- 1990-02-15 DE DE90903015T patent/DE69003936T2/de not_active Expired - Fee Related
- 1990-02-15 US US07/743,415 patent/US5245039A/en not_active Expired - Fee Related
- 1990-02-15 KR KR1019900702275A patent/KR0155557B1/ko not_active IP Right Cessation
- 1990-02-15 RU SU905001680A patent/RU2069658C1/ru active
- 1990-02-16 IE IE58490A patent/IE66498B1/en not_active IP Right Cessation
-
1991
- 1991-08-15 NO NO913188A patent/NO177186C/no unknown
- 1991-08-15 FI FI913861A patent/FI95371C/fi not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU630928B2 (en) | 1992-11-12 |
KR910700234A (ko) | 1991-03-14 |
US5245039A (en) | 1993-09-14 |
CA2047741A1 (en) | 1990-08-18 |
ATE95813T1 (de) | 1993-10-15 |
NO177186C (no) | 1995-08-02 |
EP0458823B1 (en) | 1993-10-13 |
IT8919477A0 (it) | 1989-02-17 |
IE900584L (en) | 1990-08-17 |
ES2060144T3 (es) | 1994-11-16 |
HUT62270A (en) | 1993-04-28 |
NO913188D0 (no) | 1991-08-15 |
EP0383320A1 (en) | 1990-08-22 |
FI95371B (fi) | 1995-10-13 |
FI913861A0 (fi) | 1991-08-15 |
NO177186B (no) | 1995-04-24 |
WO1990009376A1 (en) | 1990-08-23 |
FI95371C (fi) | 1996-01-25 |
EP0458823A1 (en) | 1991-12-04 |
AU5090490A (en) | 1990-09-05 |
RU2069658C1 (ru) | 1996-11-27 |
JPH04505610A (ja) | 1992-10-01 |
DK0458823T3 (da) | 1994-02-21 |
IE66498B1 (en) | 1996-01-10 |
DE69003936D1 (de) | 1993-11-18 |
DE69003936T2 (de) | 1994-03-31 |
KR0155557B1 (ko) | 1998-11-16 |
IT1230752B (it) | 1991-10-29 |
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