ATE129706T1 - Verfahren zur direkten und regioselektiven funktionalisierung in stelle 2 von phenothiazin. - Google Patents

Verfahren zur direkten und regioselektiven funktionalisierung in stelle 2 von phenothiazin.

Info

Publication number
ATE129706T1
ATE129706T1 AT91105215T AT91105215T ATE129706T1 AT E129706 T1 ATE129706 T1 AT E129706T1 AT 91105215 T AT91105215 T AT 91105215T AT 91105215 T AT91105215 T AT 91105215T AT E129706 T1 ATE129706 T1 AT E129706T1
Authority
AT
Austria
Prior art keywords
phenothiazine
direct
site
regioselective functionalization
regioselective
Prior art date
Application number
AT91105215T
Other languages
English (en)
Inventor
Mariano Meneghin
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT19976A external-priority patent/IT1240748B/it
Priority claimed from IT02107390A external-priority patent/IT1243366B/it
Application filed by Zambon Spa filed Critical Zambon Spa
Application granted granted Critical
Publication of ATE129706T1 publication Critical patent/ATE129706T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/20—[b, e]-condensed with two six-membered rings with hydrogen atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT91105215T 1990-04-09 1991-04-02 Verfahren zur direkten und regioselektiven funktionalisierung in stelle 2 von phenothiazin. ATE129706T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19976A IT1240748B (it) 1990-04-09 1990-04-09 Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina
IT02107390A IT1243366B (it) 1990-07-26 1990-07-26 Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina

Publications (1)

Publication Number Publication Date
ATE129706T1 true ATE129706T1 (de) 1995-11-15

Family

ID=26327360

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91105215T ATE129706T1 (de) 1990-04-09 1991-04-02 Verfahren zur direkten und regioselektiven funktionalisierung in stelle 2 von phenothiazin.

Country Status (6)

Country Link
US (1) US5089613A (de)
EP (1) EP0451675B1 (de)
JP (1) JPH04234865A (de)
AT (1) ATE129706T1 (de)
DE (1) DE69114166T2 (de)
ES (1) ES2079504T3 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5191078A (en) * 1989-12-21 1993-03-02 Zambon Group S.P.A. Process for the direct and regioselective functionalization in position 2 of phenothiazine
IT1244742B (it) * 1991-02-14 1994-08-08 Zambon Spa Processo per la funzionalizzazione diretta e regioselettiva in posizione 2 della fenotiazina
CN102558092B (zh) * 2011-12-20 2014-01-29 陕西科技大学 N-甲酰基吩噻嗪及其制备方法
CN105085434B (zh) * 2014-05-09 2018-02-09 上海特化医药科技有限公司 硫乙拉嗪或其中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3136762A (en) * 1964-06-09 Method of producing the same
US3413290A (en) * 1965-11-23 1968-11-26 Sandoz Ltd Phenothiazine derivatives
FR1537802A (fr) * 1967-07-11 1968-08-30 Rhone Poulenc Sa Nouveau procédé de préparation de la méthanesulfonyl-3 phénothiazine
JPS4835269B1 (de) * 1970-12-26 1973-10-26
AR205635A1 (es) * 1974-01-22 1976-05-21 Rhone Poulenc Ind Procedimiento para preparar nuevos derivados de la (((hidroxi-2 etil)-4-piperidino) -3 propil) -10 fenotiazina
GB1480553A (en) * 1976-06-03 1977-07-20 Pfizer Ltd Tricyclic sulphonamides

Also Published As

Publication number Publication date
JPH04234865A (ja) 1992-08-24
ES2079504T3 (es) 1996-01-16
DE69114166D1 (de) 1995-12-07
EP0451675B1 (de) 1995-11-02
DE69114166T2 (de) 1996-03-28
EP0451675A1 (de) 1991-10-16
US5089613A (en) 1992-02-18

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties