NO903704D0 - Nye derivater av deoksy-2'-uridin substituert i 5-,3' eller 5'-posisjon med alfa-aminoacyl-grupper, samt fremgangsmaate for fremstilling av slike forbindelser, og medikamentersom inneholder dem. - Google Patents

Nye derivater av deoksy-2'-uridin substituert i 5-,3' eller 5'-posisjon med alfa-aminoacyl-grupper, samt fremgangsmaate for fremstilling av slike forbindelser, og medikamentersom inneholder dem.

Info

Publication number
NO903704D0
NO903704D0 NO1990903704A NO903704A NO903704D0 NO 903704 D0 NO903704 D0 NO 903704D0 NO 1990903704 A NO1990903704 A NO 1990903704A NO 903704 A NO903704 A NO 903704A NO 903704 D0 NO903704 D0 NO 903704D0
Authority
NO
Norway
Prior art keywords
radical
pct
preparation
alfa
deoxy
Prior art date
Application number
NO1990903704A
Other languages
English (en)
Other versions
NO173507C (no
NO173507B (no
NO903704L (no
Inventor
Jean-Luc Moriniere
Michelle Faulques
Claude Rousseau
Bernard Danree
Claude Marquer
Patrick Saur
Jean Lemoine
Jean-Yves Lacolle
Original Assignee
Inst Rech Chim Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8802255A external-priority patent/FR2627492B1/fr
Priority claimed from FR8808684A external-priority patent/FR2633294B1/fr
Application filed by Inst Rech Chim Biolog filed Critical Inst Rech Chim Biolog
Publication of NO903704D0 publication Critical patent/NO903704D0/no
Publication of NO903704L publication Critical patent/NO903704L/no
Publication of NO173507B publication Critical patent/NO173507B/no
Publication of NO173507C publication Critical patent/NO173507C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO903704A 1988-02-24 1990-08-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av deoksy-2'.uridin substituert i 5-, 3. eller 5.-posisjon med alpha-aminoacylgrupper NO173507C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8802255A FR2627492B1 (fr) 1988-02-24 1988-02-24 Nouveaux derives de l'amino-5(prime)-dideoxy-2(prime)-5(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes
FR8808684A FR2633294B1 (fr) 1988-06-28 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes
PCT/FR1989/000072 WO1989008115A1 (fr) 1988-02-24 1989-02-23 NOUVEAUX DERIVES DE LA DEOXY-2'-URIDINE SUBSTITUEE EN POSITION 5, 3' ou 5' PAR DES GROUPEMENTS alpha-AMINO ACYLES, PROCEDE POUR LEUR OBTENTION ET MEDICAMENTS LES CONTENANT

Publications (4)

Publication Number Publication Date
NO903704D0 true NO903704D0 (no) 1990-08-23
NO903704L NO903704L (no) 1990-10-24
NO173507B NO173507B (no) 1993-09-13
NO173507C NO173507C (no) 1993-12-22

Family

ID=26226515

Family Applications (1)

Application Number Title Priority Date Filing Date
NO903704A NO173507C (no) 1988-02-24 1990-08-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av deoksy-2'.uridin substituert i 5-, 3. eller 5.-posisjon med alpha-aminoacylgrupper

Country Status (11)

Country Link
US (1) US5212161A (no)
EP (1) EP0448550B1 (no)
JP (1) JPH03504492A (no)
AT (1) ATE109789T1 (no)
AU (1) AU631119B2 (no)
DE (1) DE68917479D1 (no)
DK (1) DK200290A (no)
FI (1) FI92324C (no)
NO (1) NO173507C (no)
OA (1) OA09306A (no)
WO (1) WO1989008115A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306722A (en) * 1992-09-02 1994-04-26 Bristol-Myers Squibb Company Thymidine derivatives and therapeutic method of use
RU2111970C1 (ru) * 1996-06-25 1998-05-27 Иван Игоревич Федоров 3'-оксимино-2',3'-дидезоксинуклеозиды
ATE413881T1 (de) 1997-08-08 2008-11-15 Celmed Oncology Usa Inc Verfahren und zubereitungen um resistenz gegen biologische oder chemische therapien zu überwinden
EP1240922B1 (en) * 1997-08-08 2008-11-12 Celmed Oncology (USA), Inc. Methods and compositions for overcoming resistance to biologic and chemotherapy
US7462605B2 (en) * 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
EP1167972B1 (en) * 1998-01-23 2017-03-08 Kiadis Pharma Intellectual Property B.V. Enzyme catalyzed therapeutic agents
CN1391486A (zh) * 1999-07-22 2003-01-15 新生物公司 治疗对治疗有抗性的肿瘤的方法
US6683061B1 (en) 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
US20030212037A1 (en) * 2000-12-21 2003-11-13 Christopher Boyer Use of bvdu for inhibiting the growth of hyperproliferative cells
CA2441350A1 (en) * 2001-01-19 2002-07-25 Newbiotics, Inc. Methods to treat autoimmune and inflammatory conditions
AU2001258694A1 (en) * 2001-03-16 2002-10-03 G. Holdings Ltd. System and method for replacing identification data on a portable transaction device
CA2458408A1 (en) * 2001-08-24 2003-03-06 Koronis Pharmaceuticals, Inc. Mutagenic nucleoside analogs for the treatment of viral disease
KR100540509B1 (ko) * 2004-01-07 2006-01-11 학교법인 포항공과대학교 수화젤레이터로 사용되는 2'-데옥시우리딘 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853845A (en) * 1971-08-18 1974-12-10 Icn Pharmaceuticals 5-n-aminoacyl-5-aminouridines
US4093716A (en) * 1977-04-28 1978-06-06 Research Corporation Compositions containing 5-amino-5-deoxythymidine and pharmaceutically acceptable salts thereof
US4128639A (en) * 1977-12-14 1978-12-05 Research Corporation Nitrosourea analogs of thymidine
US4849513A (en) * 1983-12-20 1989-07-18 California Institute Of Technology Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
SE8701605D0 (sv) * 1987-04-16 1987-04-16 Astra Ab Novel medicinal compounds

Also Published As

Publication number Publication date
NO173507C (no) 1993-12-22
FI904171A0 (fi) 1990-08-23
NO173507B (no) 1993-09-13
DK200290D0 (da) 1990-08-21
ATE109789T1 (de) 1994-08-15
FI92324C (fi) 1994-10-25
AU3213789A (en) 1989-09-22
FI92324B (fi) 1994-07-15
US5212161A (en) 1993-05-18
OA09306A (fr) 1992-09-15
EP0448550A1 (fr) 1991-10-02
WO1989008115A1 (fr) 1989-09-08
DK200290A (da) 1990-08-21
NO903704L (no) 1990-10-24
JPH03504492A (ja) 1991-10-03
AU631119B2 (en) 1992-11-19
DE68917479D1 (de) 1994-09-15
EP0448550B1 (fr) 1994-08-10

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