DK200290A - Derivater af 2'-desoxyuridin substitueret i 5, 3' eller 5'-stilling med alfa-aminoacylgrupper, fremgangsmaade til deres fremstilling og laegemidler indeholdende dem - Google Patents

Derivater af 2'-desoxyuridin substitueret i 5, 3' eller 5'-stilling med alfa-aminoacylgrupper, fremgangsmaade til deres fremstilling og laegemidler indeholdende dem Download PDF

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Publication number
DK200290A
DK200290A DK200290A DK200290A DK200290A DK 200290 A DK200290 A DK 200290A DK 200290 A DK200290 A DK 200290A DK 200290 A DK200290 A DK 200290A DK 200290 A DK200290 A DK 200290A
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DK
Denmark
Prior art keywords
radical
pct
derivatives
preparation
substituted
Prior art date
Application number
DK200290A
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English (en)
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DK200290D0 (da
Inventor
Jean-Luc Moriniere
Michelle Faulques
Claude Rousseau
Bernard Danree
Claude Marquer
Patrick Saur
Jean Lemoine
Jean-Yves Lacolle
Original Assignee
Inst Rech Chim Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8802255A external-priority patent/FR2627492B1/fr
Priority claimed from FR8808684A external-priority patent/FR2633294B1/fr
Application filed by Inst Rech Chim Biolog filed Critical Inst Rech Chim Biolog
Publication of DK200290D0 publication Critical patent/DK200290D0/da
Publication of DK200290A publication Critical patent/DK200290A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK200290A 1988-02-24 1990-08-21 Derivater af 2'-desoxyuridin substitueret i 5, 3' eller 5'-stilling med alfa-aminoacylgrupper, fremgangsmaade til deres fremstilling og laegemidler indeholdende dem DK200290A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8802255A FR2627492B1 (fr) 1988-02-24 1988-02-24 Nouveaux derives de l'amino-5(prime)-dideoxy-2(prime)-5(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes
FR8808684A FR2633294B1 (fr) 1988-06-28 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes
PCT/FR1989/000072 WO1989008115A1 (fr) 1988-02-24 1989-02-23 NOUVEAUX DERIVES DE LA DEOXY-2'-URIDINE SUBSTITUEE EN POSITION 5, 3' ou 5' PAR DES GROUPEMENTS alpha-AMINO ACYLES, PROCEDE POUR LEUR OBTENTION ET MEDICAMENTS LES CONTENANT

Publications (2)

Publication Number Publication Date
DK200290D0 DK200290D0 (da) 1990-08-21
DK200290A true DK200290A (da) 1990-08-21

Family

ID=26226515

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200290A DK200290A (da) 1988-02-24 1990-08-21 Derivater af 2'-desoxyuridin substitueret i 5, 3' eller 5'-stilling med alfa-aminoacylgrupper, fremgangsmaade til deres fremstilling og laegemidler indeholdende dem

Country Status (11)

Country Link
US (1) US5212161A (da)
EP (1) EP0448550B1 (da)
JP (1) JPH03504492A (da)
AT (1) ATE109789T1 (da)
AU (1) AU631119B2 (da)
DE (1) DE68917479D1 (da)
DK (1) DK200290A (da)
FI (1) FI92324C (da)
NO (1) NO173507C (da)
OA (1) OA09306A (da)
WO (1) WO1989008115A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5306722A (en) * 1992-09-02 1994-04-26 Bristol-Myers Squibb Company Thymidine derivatives and therapeutic method of use
RU2111970C1 (ru) * 1996-06-25 1998-05-27 Иван Игоревич Федоров 3'-оксимино-2',3'-дидезоксинуклеозиды
JP2001512830A (ja) * 1997-08-08 2001-08-28 ニューバイオティックス インコーポレイテッド 生物療法耐性および化学療法耐性を克服するための方法および組成物
EP1240922B1 (en) * 1997-08-08 2008-11-12 Celmed Oncology (USA), Inc. Methods and compositions for overcoming resistance to biologic and chemotherapy
US7462605B2 (en) * 1998-01-23 2008-12-09 Celmed Oncology (Usa), Inc. Phosphoramidate compounds and methods of use
IL137164A0 (en) * 1998-01-23 2001-07-24 Newbiotics Inc Enzyme catalyzed therapeutic agents
US6683061B1 (en) * 1999-07-22 2004-01-27 Newbiotics, Inc. Enzyme catalyzed therapeutic activation
BR0012676A (pt) * 1999-07-22 2003-07-01 Newbiotics Inc Métodos para tratamento de tumores resistentes a terapia
US20030212037A1 (en) * 2000-12-21 2003-11-13 Christopher Boyer Use of bvdu for inhibiting the growth of hyperproliferative cells
AU2002241911B9 (en) * 2001-01-19 2007-01-25 Celmed Oncology (Usa), Inc. Methods to treat autoimmune and inflammatory conditions
CN1537301A (zh) * 2001-03-16 2004-10-13 G���ع����޹�˾ 在便携式事务处理装置上替换标识数据的系统和方法
WO2003018030A1 (en) * 2001-08-24 2003-03-06 Koronis Pharmaceuticals, Inc. Mutagenic nucleoside analogs for the treatment of viral disease
KR100540509B1 (ko) * 2004-01-07 2006-01-11 학교법인 포항공과대학교 수화젤레이터로 사용되는 2'-데옥시우리딘 유도체

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3853845A (en) * 1971-08-18 1974-12-10 Icn Pharmaceuticals 5-n-aminoacyl-5-aminouridines
US4093716A (en) * 1977-04-28 1978-06-06 Research Corporation Compositions containing 5-amino-5-deoxythymidine and pharmaceutically acceptable salts thereof
US4128639A (en) * 1977-12-14 1978-12-05 Research Corporation Nitrosourea analogs of thymidine
US4849513A (en) * 1983-12-20 1989-07-18 California Institute Of Technology Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups
SE8605503D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel medicinal use
SE8701605D0 (sv) * 1987-04-16 1987-04-16 Astra Ab Novel medicinal compounds

Also Published As

Publication number Publication date
ATE109789T1 (de) 1994-08-15
DK200290D0 (da) 1990-08-21
FI92324B (fi) 1994-07-15
NO903704L (no) 1990-10-24
AU3213789A (en) 1989-09-22
WO1989008115A1 (fr) 1989-09-08
OA09306A (fr) 1992-09-15
US5212161A (en) 1993-05-18
DE68917479D1 (de) 1994-09-15
NO173507B (no) 1993-09-13
NO173507C (no) 1993-12-22
NO903704D0 (no) 1990-08-23
FI92324C (fi) 1994-10-25
EP0448550B1 (fr) 1994-08-10
FI904171A0 (fi) 1990-08-23
EP0448550A1 (fr) 1991-10-02
AU631119B2 (en) 1992-11-19
JPH03504492A (ja) 1991-10-03

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AHB Application shelved due to non-payment