FR2633294B1 - Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes - Google Patents

Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes

Info

Publication number
FR2633294B1
FR2633294B1 FR8808684A FR8808684A FR2633294B1 FR 2633294 B1 FR2633294 B1 FR 2633294B1 FR 8808684 A FR8808684 A FR 8808684A FR 8808684 A FR8808684 A FR 8808684A FR 2633294 B1 FR2633294 B1 FR 2633294B1
Authority
FR
France
Prior art keywords
prime
dideoxy
compounds
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR8808684A
Other languages
English (en)
Other versions
FR2633294A1 (fr
Inventor
Jean-Luc Moriniere
Michelle Faulques
Claude Rousseau
Bernard Danree
Claude Marquer
Patrick Saur
Jean Lemoine
Jean-Yves Lacolle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Original Assignee
Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR8808684A priority Critical patent/FR2633294B1/fr
Application filed by Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA filed Critical Institut de Recherches Chimiques et Biologiques Appliquees SARL IRCEBA
Priority to US07/566,344 priority patent/US5212161A/en
Priority to AU32137/89A priority patent/AU631119B2/en
Priority to AT89903177T priority patent/ATE109789T1/de
Priority to DE68917479T priority patent/DE68917479D1/de
Priority to EP89903177A priority patent/EP0448550B1/fr
Priority to JP1502971A priority patent/JPH03504492A/ja
Priority to PCT/FR1989/000072 priority patent/WO1989008115A1/fr
Publication of FR2633294A1 publication Critical patent/FR2633294A1/fr
Priority to DK200290A priority patent/DK200290D0/da
Priority to NO903704A priority patent/NO173507C/no
Priority to FI904171A priority patent/FI92324C/fi
Priority to OA59844A priority patent/OA09306A/fr
Application granted granted Critical
Publication of FR2633294B1 publication Critical patent/FR2633294B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8808684A 1988-02-24 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes Expired - Lifetime FR2633294B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR8808684A FR2633294B1 (fr) 1988-06-28 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes
PCT/FR1989/000072 WO1989008115A1 (fr) 1988-02-24 1989-02-23 NOUVEAUX DERIVES DE LA DEOXY-2'-URIDINE SUBSTITUEE EN POSITION 5, 3' ou 5' PAR DES GROUPEMENTS alpha-AMINO ACYLES, PROCEDE POUR LEUR OBTENTION ET MEDICAMENTS LES CONTENANT
AT89903177T ATE109789T1 (de) 1988-02-24 1989-02-23 Derivate von deoxy-2'-uridin substituiert in der 5, 3' oder 5' stellung durch acylierte alpha- amino-gruppen, verfahren zur herstellung und arzneimittel daraus.
DE68917479T DE68917479D1 (de) 1988-02-24 1989-02-23 Derivate von deoxy-2'-uridin substituiert in der 5, 3' oder 5' stellung durch acylierte alpha-amino-gruppen, verfahren zur herstellung und arzneimittel daraus.
EP89903177A EP0448550B1 (fr) 1988-02-24 1989-02-23 NOUVEAUX DERIVES DE LA DEOXY-2'-URIDINE SUBSTITUEE EN POSITION 5, 3' ou 5' PAR DES GROUPEMENTS ALPHA-AMINO ACYLES, PROCEDE POUR LEUR OBTENTION ET MEDICAMENTS LES CONTENANT
JP1502971A JPH03504492A (ja) 1988-02-24 1989-02-23 α‐アミノアシル基により５‐、３’‐、又は５’‐の位置で置換された２’‐デオキシウリジンの新しい誘導体及びその生成方法及びそれらの存在する薬剤
US07/566,344 US5212161A (en) 1988-02-24 1989-02-23 Derivatives of 2'-deoxyuridine substituted in the 5-,3'-or 5'-position by α-aminacyl groups, process for their preparation and drugs in which they are present
AU32137/89A AU631119B2 (en) 1988-02-24 1989-02-23 New derivatives of deoxy-2'-uridine substituted in the 5,3' or 5' position by acylated alpha-amino groups, process for obtaining them and drugs containing them
DK200290A DK200290D0 (da) 1988-02-24 1990-08-21 Derivater af 2'-desoxyuridin substitueret i 5, 3' eller 5'-stilling med alfa-aminoacylgrupper, fremgangsmaade til deres fremstilling og laegemidler indeholdende dem
NO903704A NO173507C (no) 1988-02-24 1990-08-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive derivater av deoksy-2'.uridin substituert i 5-, 3. eller 5.-posisjon med alpha-aminoacylgrupper
FI904171A FI92324C (fi) 1988-02-24 1990-08-23 Menetelmä lääkeaineina käyttökelpoisten 2'-deoksiuridiinijohdannaisten valmistamiseksi
OA59844A OA09306A (fr) 1988-02-24 1990-08-24 "Nouveaux dérivés de la déoxy-2'-uridine substituée en position 5, 3' ou 5' par des groupements x-amino acylés, procédé pour leur obtention et médicaments les contenant".

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8808684A FR2633294B1 (fr) 1988-06-28 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes

Publications (2)

Publication Number Publication Date
FR2633294A1 FR2633294A1 (fr) 1989-12-29
FR2633294B1 true FR2633294B1 (fr) 1990-11-16

Family

ID=9367812

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8808684A Expired - Lifetime FR2633294B1 (fr) 1988-02-24 1988-06-28 Nouveaux derives de l'amino-3(prime)-dideoxy-2(prime)-3(prime)-uridine, procede pour les preparer et compositions pharmaceutiques contenant ces composes

Country Status (1)

Country Link
FR (1) FR2633294B1 (fr)

Also Published As

Publication number Publication date
FR2633294A1 (fr) 1989-12-29

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ST Notification of lapse