NO903455L - Analoger av frigjoeringshormon for luteiniserende hormon samt fremstilling derav. - Google Patents
Analoger av frigjoeringshormon for luteiniserende hormon samt fremstilling derav.Info
- Publication number
- NO903455L NO903455L NO90903455A NO903455A NO903455L NO 903455 L NO903455 L NO 903455L NO 90903455 A NO90903455 A NO 90903455A NO 903455 A NO903455 A NO 903455A NO 903455 L NO903455 L NO 903455L
- Authority
- NO
- Norway
- Prior art keywords
- hormon
- lute
- analogs
- inhibiting
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Nye "pseudo" nonapeptid og decapeptidderivater av LHRH. Mer spesielt beskrives derivater av LHRH hvor nitrogenatomet av minst en av amidbindingene har blitt alkylert.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39057289A | 1989-08-07 | 1989-08-07 | |
US07/548,512 US5110904A (en) | 1989-08-07 | 1990-07-10 | Lhrh analogs |
Publications (2)
Publication Number | Publication Date |
---|---|
NO903455D0 NO903455D0 (no) | 1990-08-06 |
NO903455L true NO903455L (no) | 1991-02-08 |
Family
ID=27013204
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO90903455A NO903455L (no) | 1989-08-07 | 1990-08-06 | Analoger av frigjoeringshormon for luteiniserende hormon samt fremstilling derav. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5110904A (no) |
EP (1) | EP0413209A1 (no) |
JP (1) | JPH03101695A (no) |
KR (1) | KR0144144B1 (no) |
AU (2) | AU6028690A (no) |
CA (1) | CA2022444C (no) |
HU (1) | HUT54387A (no) |
IE (1) | IE902740A1 (no) |
IL (1) | IL95136A0 (no) |
NO (1) | NO903455L (no) |
PL (1) | PL286388A1 (no) |
PT (1) | PT94924B (no) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8713240D0 (en) * | 1987-06-05 | 1987-07-08 | Proteus Biotech Ltd | Hormones |
US5300492A (en) * | 1988-02-10 | 1994-04-05 | Tap Pharmaceuticals | LHRH analogs |
US5110904A (en) * | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
US5686410A (en) * | 1989-07-20 | 1997-11-11 | Novartis Ag | Polypeptide derivatives |
DE3936328A1 (de) * | 1989-10-27 | 1991-05-02 | Schering Ag | Pharmazeutische praeparate |
US5352796A (en) * | 1989-10-30 | 1994-10-04 | The Salk Institute For Biological Studies | Amino acids useful in making GnRH analogs |
US5296468A (en) * | 1989-10-30 | 1994-03-22 | The Salk Institute For Biological Studies | GnRH analogs |
EP0477499B1 (de) * | 1990-08-04 | 1994-01-26 | Hoechst Aktiengesellschaft | Gonadoliberin-Antagonisten |
US5744450A (en) | 1991-03-14 | 1998-04-28 | The Salk Institute For Biological Studies | GnRH analogs |
JP2719233B2 (ja) * | 1991-04-25 | 1998-02-25 | デゲンギ,ロマノ | 黄体形成ホルモン放出ホルモン拮抗ペプチド |
JPH06509075A (ja) * | 1991-07-01 | 1994-10-13 | ユニヴァーシティ テクノロジーズ インターナショナル インコーポレイテッド | GnRH及び他の生物学的に活性なリガンドの非感度低下性類縁体 |
US5480969A (en) * | 1992-09-15 | 1996-01-02 | The Administrators Of The Tulane Educational Fund | Antagonists of LHRH |
JPH08504209A (ja) * | 1992-12-04 | 1996-05-07 | アボツト・ラボラトリーズ | 6位修飾デカペプチドlhrh拮抗薬 |
UA61046C2 (en) * | 1992-12-07 | 2003-11-17 | Takeda Chemical Industries Ltd | Sustained-release preparation and method for its manufacture |
TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
IL108509A0 (en) * | 1993-02-22 | 1994-05-30 | Salk Inst For Biological Studi | GnRH antagonist peptides |
US5413990A (en) * | 1993-08-06 | 1995-05-09 | Tap Pharmaceuticals Inc. | N-terminus modified analogs of LHRH |
US5502035A (en) * | 1993-08-06 | 1996-03-26 | Tap Holdings Inc. | N-terminus modified analogs of LHRH |
JP3662926B2 (ja) * | 1993-08-06 | 2005-06-22 | タツプ・ホールデイングス・インコーポレイテツド | Lhrhのn末端改変類似体 |
CA2143044C (en) * | 1994-02-21 | 2005-04-12 | Yasutaka Igari | Matrix for sustained-release preparation |
US5508383A (en) * | 1994-03-09 | 1996-04-16 | Tap Holdings Inc. | Cyclic peptide LHRH antagonists |
US5516759A (en) * | 1994-12-08 | 1996-05-14 | Tap Holdings Inc. | LHRH antagonists having lactam groups at the N-terminus |
US5681928A (en) * | 1994-12-16 | 1997-10-28 | The Salk Institute For Biological Studies | Betides and methods for screening peptides using same |
WO1996022786A1 (en) * | 1995-01-23 | 1996-08-01 | Takeda Chemical Industries, Ltd. | Sustained-release preparation and use |
US5843901A (en) | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
DE19544212A1 (de) * | 1995-11-28 | 1997-06-05 | Asta Medica Ag | Neue LH-RH-Antagonisten mit verbesserter Wirkung |
US5780435A (en) * | 1995-12-15 | 1998-07-14 | Praecis Pharmaceuticals Incorporated | Methods for treating prostate cancer with LHRH-R antagonists |
CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
US5710247A (en) * | 1996-03-19 | 1998-01-20 | Abbott Laboratories | Process and intermediates for the synthesis of LHRH antagonists |
US5710246A (en) * | 1996-03-19 | 1998-01-20 | Abbott Laboratories | Process for intermediates for the synthesis of LHRH antagonists |
EP0842946A1 (en) * | 1996-11-14 | 1998-05-20 | Laboratoire Theramex S.A. | Conformationally constrained LH-RH analogues, their uses and pharmaceutical compositions containing them |
US5968895A (en) * | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US5821230A (en) * | 1997-04-11 | 1998-10-13 | Ferring Bv | GnRH antagonist decapeptides |
EP0882736A1 (en) * | 1997-06-02 | 1998-12-09 | Laboratoire Theramex S.A. | LH-RH peptide analogues, their uses and pharmaceutical compositions containing them |
US6297354B1 (en) | 1998-08-12 | 2001-10-02 | Abbott Laboratories | Pentapeptide LHRH antagonists |
US6191115B1 (en) | 1998-08-12 | 2001-02-20 | Abbott Laboratories | C-terminus modified heptapeptide LHRH analogs |
US5981521A (en) * | 1998-11-13 | 1999-11-09 | Abbott Laboratories | Tetrahydroisoquinoline derivatives as LHRH antagonists |
US6455499B1 (en) | 1999-02-23 | 2002-09-24 | Indiana University Foundation | Methods for treating disorders associated with LHRH activity |
DE19911771B4 (de) | 1999-03-17 | 2006-03-30 | Zentaris Gmbh | LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung |
US6673352B1 (en) * | 1999-09-14 | 2004-01-06 | The General Hospital Corporation | Use of Mullerian inhibiting substance for treating excess androgen states |
RU2248982C9 (ru) * | 2000-03-14 | 2005-06-10 | Центарис Гмбх | Антагонисты lhrh, их получение, фармацевтическая композиция и ее получение, способ лечения опухолей и бесплодия у млекопитающих |
US20030176360A1 (en) | 2000-07-05 | 2003-09-18 | Yasutaka Igari | Medicinal preparations for treating sex hormone-dependent diseases |
US6598784B2 (en) * | 2000-12-20 | 2003-07-29 | Meadwestvaco Packaging Syatens, Llc | Beverage carton with strap type carrying handle |
CA2451187C (en) * | 2001-06-22 | 2012-08-14 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
TWI225416B (en) | 2001-06-29 | 2004-12-21 | Takeda Chemical Industries Ltd | Sustained-release composition and process for producing the same |
US7098305B2 (en) * | 2001-09-06 | 2006-08-29 | Ardana Bioscience Limited | Sustained release of microcrystalline peptide suspensions |
WO2003041739A1 (en) | 2001-11-13 | 2003-05-22 | Takeda Chemical Industries, Ltd. | Anticaner agents |
US20050159361A1 (en) * | 2002-03-11 | 2005-07-21 | Takahito Hara | Remedies for sex hormone-dependent disease |
JP2004002321A (ja) * | 2002-03-11 | 2004-01-08 | Takeda Chem Ind Ltd | 性ホルモン依存性疾患治療剤 |
AU2003262847A1 (en) * | 2002-08-23 | 2004-03-11 | The General Hospital Corporation | Use of mullerian inhibiting substance and interferon for treating tumors |
GB0326632D0 (en) | 2003-11-14 | 2003-12-17 | Jagotec Ag | Dry powder formulations |
US8882747B2 (en) * | 2005-11-09 | 2014-11-11 | The Invention Science Fund I, Llc | Substance delivery system |
EP2098507B1 (en) | 2006-11-30 | 2014-11-12 | Takeda Pharmaceutical Company Limited | Cyclic amine compound as androgen receptor modulator |
WO2010142060A1 (zh) * | 2009-06-11 | 2010-12-16 | 中国人民解放军军事医学科学院毒物药物研究所 | 长效低组胺释放副作用的lhrh拮抗剂 |
EP2552424B1 (en) | 2010-04-01 | 2018-05-09 | Chiesi Farmaceutici S.p.A. | Process for preparing carrier particles for dry powders for inhalation |
US20130177651A1 (en) | 2010-09-03 | 2013-07-11 | Pharmaterials Limited | Pharmaceutical Composition Suitable for Use in a Dry Powder Inhaler |
WO2014010614A1 (ja) | 2012-07-12 | 2014-01-16 | 武田薬品工業株式会社 | マイクロカプセル粉末の製造方法 |
US20190298836A1 (en) | 2016-11-02 | 2019-10-03 | Board Of Regents, The University Of Texas System | Dissolvable films and methods of their use |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU497512B2 (en) * | 1975-04-15 | 1978-12-14 | Ici Australia Limited | Nona and deca-peptides |
NZ188987A (en) * | 1977-11-30 | 1982-02-23 | Salk Inst For Biological Studi | Peptide analogues of luteinizing hormone releasing factor |
IT1149971B (it) * | 1979-06-11 | 1986-12-10 | Syntex Inc | Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante |
US4493934A (en) * | 1979-10-01 | 1985-01-15 | Merck & Co., Inc. | 2(3-Amino-2-oxopyrrolidin-1-yl) acetic acid and n-acylated derivatives thereof |
US4444759A (en) * | 1982-07-26 | 1984-04-24 | The Salk Institute For Biological Studies | GnRH Antagonists II |
US4547370A (en) * | 1983-11-29 | 1985-10-15 | The Salk Institute For Biological Studies | GnRH Antagonists |
US4632979A (en) * | 1984-06-18 | 1986-12-30 | Tulane Educational Fund | Therapeutic LHRH analogs |
US4760053A (en) * | 1984-08-02 | 1988-07-26 | Fernand Labrie | Combination therapy for selected sex steroid dependent cancers |
US4690916A (en) * | 1984-11-13 | 1987-09-01 | Syntex (U.S.A.) Inc. | Nona and decapeptide analogs of LHRH useful as LHRH antagonists |
US4866160A (en) * | 1985-04-09 | 1989-09-12 | The Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
US5003011A (en) * | 1985-04-09 | 1991-03-26 | The Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
US4803261A (en) * | 1986-06-27 | 1989-02-07 | The Administrators Of The Tulane Educational Fund | Method for synthesizing a peptide containing a non-peptide |
US4801577A (en) * | 1987-02-05 | 1989-01-31 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists |
US4851385A (en) * | 1987-07-15 | 1989-07-25 | Indiana University Foundation | LHRH antagonist analogs having low histamine-release activity |
US4935491A (en) * | 1987-08-24 | 1990-06-19 | Board Of Regents, The University Of Texas System | Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine |
ES2108684T3 (es) * | 1988-02-10 | 1998-01-01 | Tap Pharmaceuticals Inc | Analogo de la hormona de liberacion de la hormona luteinizante (lhrh). |
US5110904A (en) * | 1989-08-07 | 1992-05-05 | Abbott Laboratories | Lhrh analogs |
US5140009A (en) * | 1988-02-10 | 1992-08-18 | Tap Pharmaceuticals, Inc. | Octapeptide LHRH antagonists |
-
1990
- 1990-07-10 US US07/548,512 patent/US5110904A/en not_active Expired - Lifetime
- 1990-07-20 IL IL95136A patent/IL95136A0/xx unknown
- 1990-07-27 IE IE274090A patent/IE902740A1/en unknown
- 1990-08-01 CA CA002022444A patent/CA2022444C/en not_active Expired - Lifetime
- 1990-08-02 EP EP90114829A patent/EP0413209A1/en not_active Withdrawn
- 1990-08-06 HU HU904910A patent/HUT54387A/hu unknown
- 1990-08-06 NO NO90903455A patent/NO903455L/no unknown
- 1990-08-06 KR KR1019900011999A patent/KR0144144B1/ko not_active IP Right Cessation
- 1990-08-06 PT PT94924A patent/PT94924B/pt not_active IP Right Cessation
- 1990-08-07 JP JP2209058A patent/JPH03101695A/ja active Pending
- 1990-08-07 PL PL28638890A patent/PL286388A1/xx unknown
- 1990-08-07 AU AU60286/90A patent/AU6028690A/en not_active Abandoned
-
1994
- 1994-03-17 AU AU57892/94A patent/AU672474B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU5789294A (en) | 1994-05-26 |
CA2022444C (en) | 2002-01-15 |
US5110904A (en) | 1992-05-05 |
JPH03101695A (ja) | 1991-04-26 |
PT94924A (pt) | 1991-05-22 |
PT94924B (pt) | 1997-09-30 |
PL286388A1 (en) | 1991-05-06 |
EP0413209A1 (en) | 1991-02-20 |
IL95136A0 (en) | 1991-06-10 |
AU6028690A (en) | 1991-02-07 |
KR910004661A (ko) | 1991-03-29 |
AU672474B2 (en) | 1996-10-03 |
NO903455D0 (no) | 1990-08-06 |
CA2022444A1 (en) | 1991-02-08 |
KR0144144B1 (ko) | 1998-07-01 |
IE902740A1 (en) | 1991-02-27 |
HUT54387A (en) | 1991-02-28 |
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