NO890892L - 1,3,4,5-tetrahydrobenz(c,d)indoler. - Google Patents

1,3,4,5-tetrahydrobenz(c,d)indoler.

Info

Publication number
NO890892L
NO890892L NO89890892A NO890892A NO890892L NO 890892 L NO890892 L NO 890892L NO 89890892 A NO89890892 A NO 89890892A NO 890892 A NO890892 A NO 890892A NO 890892 L NO890892 L NO 890892L
Authority
NO
Norway
Prior art keywords
tetrahydrobenz
indole
indoles
medicaments
amines
Prior art date
Application number
NO89890892A
Other languages
English (en)
Norwegian (no)
Other versions
NO890892D0 (no
Inventor
Bodo Junge
Bernd Richter
Thomas Glaser
Joerg Traber
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO890892D0 publication Critical patent/NO890892D0/no
Publication of NO890892L publication Critical patent/NO890892L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO89890892A 1988-03-18 1989-03-02 1,3,4,5-tetrahydrobenz(c,d)indoler. NO890892L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3809155A DE3809155A1 (de) 1988-03-18 1988-03-18 1,3,4,5-tetrahydrobenz-(c,d)-indole

Publications (2)

Publication Number Publication Date
NO890892D0 NO890892D0 (no) 1989-03-02
NO890892L true NO890892L (no) 1989-09-19

Family

ID=6350115

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89890892A NO890892L (no) 1988-03-18 1989-03-02 1,3,4,5-tetrahydrobenz(c,d)indoler.

Country Status (18)

Country Link
US (1) US5021438A (ja)
EP (1) EP0332968B1 (ja)
JP (1) JPH02204479A (ja)
KR (1) KR890014474A (ja)
CN (1) CN1036566A (ja)
AT (1) ATE90093T1 (ja)
AU (1) AU614343B2 (ja)
DD (1) DD283606A5 (ja)
DE (2) DE3809155A1 (ja)
DK (1) DK131789A (ja)
ES (1) ES2058365T3 (ja)
FI (1) FI891252A (ja)
HU (1) HU204034B (ja)
IL (1) IL89623A (ja)
NO (1) NO890892L (ja)
NZ (1) NZ228341A (ja)
PT (1) PT90012B (ja)
ZA (1) ZA892049B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3826371A1 (de) * 1988-08-03 1990-02-08 Bayer Ag Tetrahydro-1-benz-(c,d)-indolpropionsaeure-sulfonamide
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
TW219933B (ja) * 1990-02-26 1994-02-01 Lilly Co Eli
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
US5212319A (en) * 1990-02-26 1993-05-18 Eli Lilly And Company Intermediates to 4-amino-hexahydrobenz[cd]indoles and processes therefor
DE69114210T2 (de) * 1990-08-13 1996-05-02 Hoechst Roussel Pharma Carbamoyl-1-(pyridinylalkyl)-1H-indole, -indoline und verwandte Verbindungen.
US5264442A (en) * 1990-08-13 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5364856A (en) * 1991-03-28 1994-11-15 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[CD]indoles
US5656653A (en) * 1991-03-28 1997-08-12 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenz[cd]indoles
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
NZ260667A (en) * 1993-06-10 1997-05-26 Lilly Co Eli Preventing emesis or treating sexual dysfunction using tetrahydrobenz[cd]indole 6-carboxamides
TW430660B (en) * 1996-05-30 2001-04-21 Mochida Pharm Co Ltd Novel benzindole derivatives for neuron cell protection, processes for production, and the pharmaceutical compounds containing them
KR20030024799A (ko) * 2000-07-20 2003-03-26 뉴로젠 코포레이션 캡사이신 수용체 리간드
JP2022523774A (ja) 2019-02-27 2022-04-26 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 脳障害を治療するためのｎ－置換インドール及び他の複素環化合物
BR112021016620A2 (pt) 2019-02-27 2021-11-03 Univ California Azepino-indóis e outros heterociclos para o tratamento de distúrbios cerebrais
US20230295106A1 (en) * 2019-10-14 2023-09-21 The Regents Of The University Of California Ergoline-like compounds for promoting neural plasticity
CN115584206A (zh) * 2022-10-13 2023-01-10 吕辉 一种水性无机纳米陶瓷阻燃涂料及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE542760A (ja) * 1954-11-12
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4282240A (en) * 1979-11-23 1981-08-04 Merck & Co., Inc. Amino substituted tetrahydrobenzindoles
FR2471373A1 (fr) * 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux derives de la benzindolamine, leurs sels, procede de preparation, application a titre de medicaments et composition les renfermant
DE3346513A1 (de) 1983-12-22 1985-07-11 Süddeutsche Kühlerfabrik Julius Fr. Behr GmbH & Co. KG, 7000 Stuttgart Vorrichtung zum erwaermen von wasser
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4683313A (en) * 1985-06-24 1987-07-28 Eli Lilly And Company 2-alkyl(or phenyl)thio-6-N alkyl ergolines and 4-dialkylaminotetrahydrobenz[c,d]indoles
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
DE3718892A1 (de) * 1987-06-05 1988-12-22 Bayer Ag Polyhydrobenz(c,d)indol-sulfonamide

Also Published As

Publication number Publication date
AU3152689A (en) 1989-09-28
FI891252A (fi) 1989-09-19
FI891252A0 (fi) 1989-03-16
DK131789D0 (da) 1989-03-17
PT90012B (pt) 1994-06-30
PT90012A (pt) 1989-11-10
DE58904539D1 (de) 1993-07-08
AU614343B2 (en) 1991-08-29
NZ228341A (en) 1990-12-21
IL89623A (en) 1993-01-14
DD283606A5 (de) 1990-10-17
EP0332968B1 (de) 1993-06-02
HUT50767A (en) 1990-03-28
US5021438A (en) 1991-06-04
ES2058365T3 (es) 1994-11-01
CN1036566A (zh) 1989-10-25
ATE90093T1 (de) 1993-06-15
DK131789A (da) 1989-09-19
NO890892D0 (no) 1989-03-02
HU204034B (en) 1991-11-28
ZA892049B (en) 1989-11-29
IL89623A0 (en) 1989-09-10
KR890014474A (ko) 1989-10-23
DE3809155A1 (de) 1989-09-28
JPH02204479A (ja) 1990-08-14
EP0332968A1 (de) 1989-09-20

Similar Documents

Publication Publication Date Title
DE58904539D1 (de) 1,3,4,5-tetrahydrobenz(c,d)indole.
IT8548435A0 (it) Derivato di indolo,composizione farmaceutica che lo contiene e procedimento per prepararlo
MY109880A (en) Substituted biphenylpyridones
LU91758I2 (fr) Denosumab et ses dérivés pharmaceutiquement acceptables (PROLIA®)
KR950700906A (ko) 5-ht1 작동약으로서의 인돌 유도체(indole derivatives as 5-ht1 agonists)
DK162985C (da) Pyridazinderivater, som i 3-stillingen er substitueret med amino, og som indvirker paa centralnervesystemet, fremgangsmaade til fremstilling heraf og laegemidler med indhold heraf
DE3771376D1 (de) Indol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NO931040D0 (no) Indol- og indazolderivater, fremgangsmaate til fremstilling og anvendelse derav
BR9100767A (pt) Composto,formulacao farmaceutica e metodo para a preparacao de hipurato de 4-(di-n-propil)amino-1,3,4,5-tetrahidrobenz(cd)indol cristalino
DE59003994D1 (de) Substituierte 1,8-Naphthyridine.
DE69719563D1 (de) Pharmazeutische wirksame trizyklische amine
DK581183A (da) 2-azabicyclo(2.2.1)heptan-derivater, fremgangsmaader til deres fremstilling, midler indeholdende disse derivater og deres anvendelse, samt 2-azabicyclo(2.2.1)heptan-derivater som mellemprodukter samt fremgangsmaader til deres fremstilling
ZA872263B (en) Indole derivatives,processes for their preparation and pharmaceutical composition for the treatment for migraine
GR3015373T3 (en) 2-Halogen-substituted N-indolyl sulfonic-acid amides, process for their preparation and their pharmaceutical use.
DK590984A (da) Pyrrolo(3,2,1-hi)indol-derivater, fremgangsmaade til fremstilling deraf samt anvendelse af saadanne forbindelser som laegemidler
DK115289A (da) Tricykliske aminderivater, fremgangsmaade til fremstilling heraf samt farmaceutiske midler indeholdende disse
IT1227852B (it) Procedimento per preparare derivati della 1,5 benzotiazepina.
NO911810L (no) Pyrrolo(2,3-b)indol-ketoner og analoger, fremgangsmaate for fremstilling og anvendelse som medikamenter.
ATE92317T1 (de) Verwendung von pyrrol(3,2,1-hi>indol-derivaten zur herstellung eines arzneimittels zur behandlung von diabetes.
IT1207805B (it) Procedimento per preparare coniugati di metalloproteine e nuovi derivati dei coniugati stessi.
IT8919648A0 (it) Derivati dell'indolo, procedimento per la loro preparazione e mezzi farmaceutici contenenti tali composti.
YU32691A (sh) 6-supstituisani-heksahidrobenz c,d indoli i postupak za njegovo dobijanje
IT8719026A0 (it) Procedimento per preparare derivati alcossi alchiliden, idrazino, piridazinici.
NO923592L (no) Polyhydroksycyklopentanderivat og fremgangsmaate til fremstilling derav, samt mikroorganisme som er anvendelig i fremgangsmaaten
IT8621930A0 (it) Derivati della carnosina, procedimento per la loro preparazione e loro impiego.