NO881190L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider. - Google Patents
Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider.Info
- Publication number
- NO881190L NO881190L NO881190A NO881190A NO881190L NO 881190 L NO881190 L NO 881190L NO 881190 A NO881190 A NO 881190A NO 881190 A NO881190 A NO 881190A NO 881190 L NO881190 L NO 881190L
- Authority
- NO
- Norway
- Prior art keywords
- hiv
- virus
- azido
- cells
- hypoxanthine
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 15
- 238000002360 preparation method Methods 0.000 title description 8
- 230000001225 therapeutic effect Effects 0.000 title 1
- IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 claims description 38
- FDGQSTZJBFJUBT-UHFFFAOYSA-N hypoxanthine Chemical group O=C1NC=NC2=C1NC=N2 FDGQSTZJBFJUBT-UHFFFAOYSA-N 0.000 claims description 16
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical group O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 14
- 150000001875 compounds Chemical class 0.000 claims description 13
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- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873708849 DE3708849A1 (de) | 1987-03-18 | 1987-03-18 | Arzneimittel zur behandlung von viruserkrankungen |
| US07/041,147 US4880782A (en) | 1986-11-21 | 1987-04-22 | Method of treating viral infections in humans and compositions therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO881190D0 NO881190D0 (no) | 1988-03-17 |
| NO881190L true NO881190L (no) | 1988-09-19 |
Family
ID=25853652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO881190A NO881190L (no) | 1987-03-18 | 1988-03-17 | Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0286825A3 (fr) |
| AU (1) | AU609099B2 (fr) |
| DK (1) | DK147088A (fr) |
| HU (1) | HU211508A9 (fr) |
| NO (1) | NO881190L (fr) |
| NZ (1) | NZ223865A (fr) |
| PT (1) | PT87004B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5077279A (en) * | 1986-05-01 | 1991-12-31 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition |
| US5084445A (en) * | 1986-05-01 | 1992-01-28 | University Of Georgia Research Foundation, Inc. | 3'-azido-2',3'-dideoxy-5-methylcytidine |
| JPH01265099A (ja) * | 1987-10-08 | 1989-10-23 | Stichting Rega Vzw | 抗ｈｉｖ活性をもつ３’，−フルオロプリン−２’，３’−ジデオキシリボシド類 |
| US5157114A (en) * | 1988-08-19 | 1992-10-20 | Burroughs Wellcome Co. | 2',3'-dideoxy-3'-fluoro-5-ethyngluridine |
| SE464168B (sv) * | 1989-07-19 | 1991-03-18 | Bo Fredrik Oeberg | Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt) |
| KR910007655A (ko) * | 1989-10-03 | 1991-05-30 | 엠. 피. 잭슨 | 치료용 뉴클레오시드 |
| WO1991006554A1 (fr) * | 1989-11-06 | 1991-05-16 | Nycomed As | Derives de nucleosides |
| SE9003151D0 (sv) * | 1990-10-02 | 1990-10-02 | Medivir Ab | Nucleoside derivatives |
| GB9105899D0 (en) * | 1991-03-20 | 1991-05-08 | Wellcome Found | Therapeutic nucleosides |
| US5869493A (en) | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD209197A1 (de) * | 1981-07-21 | 1984-04-25 | Akad Wissenschaften Ddr | Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyguanosin |
| SU1053474A1 (ru) * | 1982-02-08 | 1985-08-07 | Институт биоорганической химии АН БССР | 3-Фтор-2,3-дидезоксигуанозин,про вл ющий цитостатическую активность |
| US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
| CA1285935C (fr) * | 1985-03-16 | 1991-07-09 | Janet Lister Rideout | Nucleosides therapeutiques |
| EP0196185B1 (fr) * | 1985-03-16 | 1989-07-12 | The Wellcome Foundation Limited | Nucléosides antiviraux |
| GB2181128A (en) * | 1985-09-17 | 1987-04-15 | Wellcome Found | 3'-azidonucleosides |
| DE3739432A1 (de) * | 1987-02-24 | 1989-06-01 | Multivac Haggenmueller Kg | Verpackungsmaschine |
-
1988
- 1988-03-07 EP EP88103543A patent/EP0286825A3/fr not_active Ceased
- 1988-03-11 NZ NZ223865A patent/NZ223865A/xx unknown
- 1988-03-14 AU AU13081/88A patent/AU609099B2/en not_active Ceased
- 1988-03-17 NO NO881190A patent/NO881190L/no unknown
- 1988-03-17 DK DK147088A patent/DK147088A/da not_active Application Discontinuation
- 1988-03-17 PT PT87004A patent/PT87004B/pt not_active IP Right Cessation
-
1995
- 1995-06-22 HU HU95P/P00374P patent/HU211508A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK147088A (da) | 1988-09-19 |
| AU1308188A (en) | 1988-09-22 |
| EP0286825A2 (fr) | 1988-10-19 |
| PT87004A (pt) | 1988-04-01 |
| PT87004B (pt) | 1992-06-30 |
| EP0286825A3 (fr) | 1989-04-12 |
| AU609099B2 (en) | 1991-04-26 |
| DK147088D0 (da) | 1988-03-17 |
| NZ223865A (en) | 1990-06-26 |
| HU211508A9 (en) | 1995-11-28 |
| NO881190D0 (no) | 1988-03-17 |
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