NO881190L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider.

Info

Publication number
NO881190L
NO881190L NO881190A NO881190A NO881190L NO 881190 L NO881190 L NO 881190L NO 881190 A NO881190 A NO 881190A NO 881190 A NO881190 A NO 881190A NO 881190 L NO881190 L NO 881190L
Authority
NO
Norway
Prior art keywords
hiv
virus
azido
cells
hypoxanthine
Prior art date
Application number
NO881190A
Other languages
English (en)
Norwegian (no)
Other versions
NO881190D0 (no
Inventor
Fritz Eckstein
Gerhard Hunsmann
Heinz Hartmann
Original Assignee
Max Planck Gesellschaft
Deutsches Primatenzentrum Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19873708849 external-priority patent/DE3708849A1/de
Priority claimed from US07/041,147 external-priority patent/US4880782A/en
Application filed by Max Planck Gesellschaft, Deutsches Primatenzentrum Gmbh filed Critical Max Planck Gesellschaft
Publication of NO881190D0 publication Critical patent/NO881190D0/no
Publication of NO881190L publication Critical patent/NO881190L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO881190A 1987-03-18 1988-03-17 Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider. NO881190L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19873708849 DE3708849A1 (de) 1987-03-18 1987-03-18 Arzneimittel zur behandlung von viruserkrankungen
US07/041,147 US4880782A (en) 1986-11-21 1987-04-22 Method of treating viral infections in humans and compositions therefor

Publications (2)

Publication Number Publication Date
NO881190D0 NO881190D0 (no) 1988-03-17
NO881190L true NO881190L (no) 1988-09-19

Family

ID=25853652

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881190A NO881190L (no) 1987-03-18 1988-03-17 Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider.

Country Status (7)

Country Link
EP (1) EP0286825A3 (fr)
AU (1) AU609099B2 (fr)
DK (1) DK147088A (fr)
HU (1) HU211508A9 (fr)
NO (1) NO881190L (fr)
NZ (1) NZ223865A (fr)
PT (1) PT87004B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
JPH01265099A (ja) * 1987-10-08 1989-10-23 Stichting Rega Vzw 抗hiv活性をもつ3’,−フルオロプリン−2’,3’−ジデオキシリボシド類
US5157114A (en) * 1988-08-19 1992-10-20 Burroughs Wellcome Co. 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
KR910007655A (ko) * 1989-10-03 1991-05-30 엠. 피. 잭슨 치료용 뉴클레오시드
WO1991006554A1 (fr) * 1989-11-06 1991-05-16 Nycomed As Derives de nucleosides
SE9003151D0 (sv) * 1990-10-02 1990-10-02 Medivir Ab Nucleoside derivatives
GB9105899D0 (en) * 1991-03-20 1991-05-08 Wellcome Found Therapeutic nucleosides
US5869493A (en) 1996-02-16 1999-02-09 Medivir Ab Acyclic nucleoside derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD209197A1 (de) * 1981-07-21 1984-04-25 Akad Wissenschaften Ddr Verfahren zur herstellung von 3'-fluor-2',3'-didesoxyguanosin
SU1053474A1 (ru) * 1982-02-08 1985-08-07 Институт биоорганической химии АН БССР 3-Фтор-2,3-дидезоксигуанозин,про вл ющий цитостатическую активность
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
CA1285935C (fr) * 1985-03-16 1991-07-09 Janet Lister Rideout Nucleosides therapeutiques
EP0196185B1 (fr) * 1985-03-16 1989-07-12 The Wellcome Foundation Limited Nucléosides antiviraux
GB2181128A (en) * 1985-09-17 1987-04-15 Wellcome Found 3'-azidonucleosides
DE3739432A1 (de) * 1987-02-24 1989-06-01 Multivac Haggenmueller Kg Verpackungsmaschine

Also Published As

Publication number Publication date
DK147088A (da) 1988-09-19
AU1308188A (en) 1988-09-22
EP0286825A2 (fr) 1988-10-19
PT87004A (pt) 1988-04-01
PT87004B (pt) 1992-06-30
EP0286825A3 (fr) 1989-04-12
AU609099B2 (en) 1991-04-26
DK147088D0 (da) 1988-03-17
NZ223865A (en) 1990-06-26
HU211508A9 (en) 1995-11-28
NO881190D0 (no) 1988-03-17

Similar Documents

Publication Publication Date Title
US4880782A (en) Method of treating viral infections in humans and compositions therefor
EP0216510B1 (fr) Inhibition de l'infectivité in vitro et de l'effet cytopathique du HTLV-III/LAV par la 2'3'-didéoxyinosine, la 2'3'-didéoxyguanosine ou par la 2'3'-didéoxyadénosine
Baba et al. Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase.
EP0355135B1 (fr) Nucleosides anti-retroviraux d'adenosine stables sous l'influence de la deaminase d'adenosine
Hayashi et al. Cyclobut-A and cyclobut-G, carbocyclic oxetanocin analogs that inhibit the replication of human immunodeficiency virus in T cells and monocytes and macrophages in vitro
Hostetler et al. Greatly enhanced inhibition of human immunodeficiency virus type 1 replication in CEM and HT4-6C cells by 3'-deoxythymidine diphosphate dimyristoylglycerol, a lipid prodrug of 3'-deoxythymidine
CA1286991C (fr) Medicament pour le traitement des infections a virus
Pauwels et al. Investigations on the anti-HIV activity of 2′, 3′-dideoxyadenosine analogues with modifications in either the pentose or purine moiety: Potent and selective anti-HIV activity of 2, 6-diaminopurine 2′, 3′-dideoxyriboside
NO881190L (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 9-(beta-d-deoxyribofuranosyl)-mucleosider.
US5616566A (en) Method of inhibiting HIV replication with 2',3'-dideoxyadenosine
EP0355825A2 (fr) Système du traitement viral
EP0216511B1 (fr) Inhibition de l'infectivité in vitro et de l'effet cytopathique du HTLV-III/LAV par la 2'3'-didéoxycytidine
Ohrui et al. 4'-C-Substituted-2'-Deoxynucleosides A Family of Antiretroviral Agents Which are Potent Against Drug-Resistant HIV Variants.
Jeffries The antiviral activity of dideoxycytidine
WO1988003804A2 (fr) Procede pour traiter des infections virales chez des humains, et compositions a cet effet
Jeffries Targets for antiviral therapy of human immunodeficiency virus infection
Shirasaka et al. Lipophilic 6-halo-2′, 3′-dideoxypurine nucleosides: potential antiretroviral agents targeting HIV-associated neurologic disorders
EP0493378A1 (fr) Utilisation de la 2',3'-dideoxyguanosine pour le traitement du SIDA
EP0464137A1 (fr) Inhibition du virus d'immunodeficience humaine (hiv) par des combinaisons a effet synergique de derives de nucleosides
NO904150L (no) Antivirale midler og fremgangsmaate for aa oeke den antivirale aktivitet av azt.
IE19940570A1 (en) Use of 2',3'-dideoxyguanosine for the treatment of AIDS
IE83887B1 (en) Use of 2',3'-dideoxyguanosine for the treatment of AIDS