NO874350L - Fremgangsmaate for fremstilling av antibakterielle forbindelser. - Google Patents

Fremgangsmaate for fremstilling av antibakterielle forbindelser.

Info

Publication number
NO874350L
NO874350L NO874350A NO874350A NO874350L NO 874350 L NO874350 L NO 874350L NO 874350 A NO874350 A NO 874350A NO 874350 A NO874350 A NO 874350A NO 874350 L NO874350 L NO 874350L
Authority
NO
Norway
Prior art keywords
procedure
manufacture
antibacterial compounds
compounds
chem
Prior art date
Application number
NO874350A
Other languages
English (en)
Other versions
NO874350D0 (no
Inventor
John Michael Domagala
Thomas Frederick Mich
Joseph Peter Sanchez
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO874350D0 publication Critical patent/NO874350D0/no
Publication of NO874350L publication Critical patent/NO874350L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO874350A 1986-10-20 1987-10-19 Fremgangsmaate for fremstilling av antibakterielle forbindelser. NO874350L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/920,536 US4822801A (en) 1984-07-20 1986-10-20 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents

Publications (2)

Publication Number Publication Date
NO874350D0 NO874350D0 (no) 1987-10-19
NO874350L true NO874350L (no) 1988-04-21

Family

ID=25443916

Family Applications (1)

Application Number Title Priority Date Filing Date
NO874350A NO874350L (no) 1986-10-20 1987-10-19 Fremgangsmaate for fremstilling av antibakterielle forbindelser.

Country Status (17)

Country Link
US (1) US4822801A (no)
EP (1) EP0265230B1 (no)
JP (2) JP2750117B2 (no)
KR (1) KR880005137A (no)
AT (1) ATE71375T1 (no)
AU (1) AU643489B2 (no)
CA (1) CA1336089C (no)
DE (1) DE3775882D1 (no)
DK (1) DK543787A (no)
ES (1) ES2040261T3 (no)
FI (1) FI874570A (no)
GR (1) GR3003548T3 (no)
IE (1) IE64492B1 (no)
NO (1) NO874350L (no)
PH (3) PH24199A (no)
PT (1) PT85943B (no)
ZA (1) ZA877887B (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
JPH0228178A (ja) * 1988-04-23 1990-01-30 Toyama Chem Co Ltd 新規なピリドンカルボン酸誘導体およびその塩並びにそれらの製造法
KR910003630B1 (ko) * 1988-06-17 1991-06-07 한국과학기술원 벤조일 아세틱 에스테르 유도체 및 그 제조방법
JPH0674261B2 (ja) * 1988-06-21 1994-09-21 塩野義製薬株式会社 キノロンカルボン酸誘導体
FI95130C (fi) * 1988-07-20 1995-12-27 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
CA2078444A1 (en) 1990-04-18 1991-10-19 Thomas P. Demuth, Jr. Antimicrobial quinolonyl lactams
ES2167329T3 (es) * 1992-01-31 2002-05-16 Chugai Pharmaceutical Co Ltd Cristal de hidrato de derivado de acido quinolonacarboxilico.
US5646163A (en) * 1992-10-30 1997-07-08 The Procter & Gamble Company Quinolone 5-(N-heterosubstituted amino) antimicrobials
RU2140919C1 (ru) * 1994-07-18 1999-11-10 Убе Индастриз Лтд. Производные 8-трифторметилхинолинкарбоновой кислоты, фармацевтическая композиция и способ ингибирования вируса иммунодефицита
US5602254A (en) * 1995-05-26 1997-02-11 Warner-Lambert Company Method for making quinoline carboxylic acids or naphthyridine carboxylic acids in free base form
DE19652239A1 (de) * 1996-12-16 1998-06-18 Bayer Ag Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen
CN1264837C (zh) 1997-09-15 2006-07-19 普罗克特和甘保尔公司 喹诺酮抗微生物剂、其组合物和应用
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
US7098219B2 (en) 2000-08-01 2006-08-29 Wockhart Limited Inhibitors of cellular efflux pumps of microbes
US6964966B2 (en) 2001-04-25 2005-11-15 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6878713B2 (en) 2001-04-25 2005-04-12 Wockhardt Limited Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
KR20040094806A (ko) * 2002-03-18 2004-11-10 교린 세이야꾸 가부시키 가이샤 내성균에 유효한10-(3-시클로프로필아미노메틸-1-피로리디닐)피리도벤즈옥사진 카르본산 유도체
WO2003099815A1 (en) * 2002-05-28 2003-12-04 Wockhardt Limited Crystalline fluoroquinolone arginine salt form
CA2537066C (en) * 2003-09-04 2011-05-24 Wockhardt Limited Benzoquinolizine-2-carboxylic acid arginine salt tetrahydrate
PT1666477E (pt) * 2003-09-10 2013-08-28 Kyorin Seiyaku Kk Derivado de 7-(4-substituído-3-ciclopropilaminometil-1- pirrolidinil) quinolonecarboxílico
WO2005111030A1 (en) * 2004-05-12 2005-11-24 Warner-Lambert Company Llc Quinolone antibacterial agents
US20090156577A1 (en) * 2004-09-09 2009-06-18 Benjamin Davis 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
US7563805B2 (en) 2005-05-19 2009-07-21 Daiichi Pharmaceutical Co., Ltd. Tri-, tetra-substituted-3-aminopyrrolidine derivative
CN101443314B (zh) 2006-03-13 2014-04-09 杏林制药株式会社 作为gsk-3抑制剂的氨基喹诺酮类
BRPI0709772B8 (pt) * 2006-03-28 2021-05-25 The Protecter & Gamble Company sais de malato e polimorfos do ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-diidro-8-metóxi-4-oxo-3-quinolinocarboxílico
US7528264B2 (en) * 2006-03-28 2009-05-05 The Procter & Gamble Company Hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
WO2008143343A1 (ja) * 2007-05-24 2008-11-27 Kyorin Pharmaceutical Co., Ltd. １４位置換基に複素芳香環カルボン酸構造を有するムチリン誘導体
US7902227B2 (en) * 2007-07-27 2011-03-08 Janssen Pharmaceutica Nv. C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
AU2008299903B2 (en) 2007-09-11 2013-08-29 Kyorin Pharmaceutical Co., Ltd Cyanoaminoquinolones and tetrazoloaminoquinolones as GSK-3 inhibitors
KR101597841B1 (ko) 2007-09-12 2016-02-26 교린 세이야꾸 가부시키 가이샤 Ｇｓｋ-３ 억제제로서의 스피로시클릭 아미노퀴놀론
WO2009064836A2 (en) * 2007-11-15 2009-05-22 University Of Maryland, Baltimore Kynurenine-aminotransferase inhibitors
MX2011009414A (es) * 2009-03-11 2011-10-19 Kyorin Seiyaku Kk 7-cicloalquiloaminoquinolonas como inhibidores de gsk-3.
WO2014125506A2 (en) * 2013-02-15 2014-08-21 Laurus Labs Private Limited A process for the preparation of ivacaftor and its intermediates
KR102213991B1 (ko) * 2014-05-20 2021-02-09 동화약품주식회사 개선된 자보플록사신의 제조방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049811A (en) * 1968-07-23 1977-09-20 Boehringer Mannheim G.M.B.H. Compositions using cycloalkano-quinolone derivatives and their method of use
JPS5746986A (en) * 1980-09-02 1982-03-17 Dai Ichi Seiyaku Co Ltd Pyrido(1,2,3-de)(1,4)benzoxazine derivative
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
IE58742B1 (en) * 1984-07-20 1993-11-05 Warner Lambert Co Substituted-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7h-pyrido[1,2,3-de] [1,4]benzoxauine-6-carboxylic acids; sibstituted-5-amino-6-6fluoro-4-oxo.1,4-dihydroquinoline-3 carboxylic acids; substituted-5-amino-6-fluoro-1,4-dihydro-4-oxo-1.8-naphthyridine-3-carboxylic acids; derivatives thereof; pharmaceutical compositions comprising the compounds; and processes for producing the compounds
US4604401A (en) * 1984-07-20 1986-08-05 Warner-Lambert Company Antibacterial agents III
AU576272B2 (en) * 1984-11-13 1988-08-18 Kyorin Pharmaceutical Co. Ltd. Quinolone carboxylic acid derivates
AU578793B2 (en) * 1985-02-15 1988-11-03 Dainippon Pharmaceutical Co. Ltd. Novel 1,8-naphthyridine derivatives and processes for preparation thereof
JPH089597B2 (ja) * 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
JPH0720940B2 (ja) * 1986-02-28 1995-03-08 大日本製薬株式会社 キノリン誘導体の製造法
US4780408A (en) * 1986-03-26 1988-10-25 Colorado State University Research Foundation Antibody for detection and quantification of trifluralin
JPH0720941B2 (ja) * 1986-03-28 1995-03-08 大日本製薬株式会社 新規キノロン誘導体、そのエステルおよびその塩
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
US4771055A (en) * 1986-07-28 1988-09-13 Warner-Lambert Company 7-[[3-(aminomethyl)-3-alkyl]-1-pyrrolidinyl]-quinoline-carboxylic acids
JPS63152318A (ja) * 1986-08-07 1988-06-24 Dainippon Pharmaceut Co Ltd 抗マイコプラズマ剤

Also Published As

Publication number Publication date
PH24199A (en) 1990-04-10
JP3235539B2 (ja) 2001-12-04
CA1336089C (en) 1995-06-27
AU6920591A (en) 1991-03-28
IE64492B1 (en) 1995-08-09
US4822801A (en) 1989-04-18
EP0265230A1 (en) 1988-04-27
AU7987987A (en) 1988-04-21
KR880005137A (ko) 1988-06-28
PT85943B (pt) 1990-07-31
ES2040261T3 (es) 1993-10-16
GR3003548T3 (no) 1993-03-16
FI874570A0 (fi) 1987-10-16
IE872590L (en) 1988-04-20
DK543787A (da) 1988-04-21
DE3775882D1 (de) 1992-02-20
DK543787D0 (da) 1987-10-16
EP0265230B1 (en) 1992-01-08
ATE71375T1 (de) 1992-01-15
PH25459A (en) 1991-07-01
JPH10114779A (ja) 1998-05-06
ZA877887B (en) 1989-05-30
JP2750117B2 (ja) 1998-05-13
AU643489B2 (en) 1993-11-18
AU606618B2 (en) 1991-02-14
PT85943A (en) 1987-11-01
FI874570A (fi) 1988-04-21
NO874350D0 (no) 1987-10-19
PH25423A (en) 1991-07-01
JPS63104974A (ja) 1988-05-10

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