NO872971L - FremgangsmŸte ved fremstilling av 5,6-substituerte 2,4-kinazolindiaminer og nye mellomprodukter. - Google Patents

FremgangsmŸte ved fremstilling av 5,6-substituerte 2,4-kinazolindiaminer og nye mellomprodukter.

Info

Publication number
NO872971L
NO872971L NO872971A NO872971A NO872971L NO 872971 L NO872971 L NO 872971L NO 872971 A NO872971 A NO 872971A NO 872971 A NO872971 A NO 872971A NO 872971 L NO872971 L NO 872971L
Authority
NO
Norway
Prior art keywords
preparation
chinazoline
diamines
substituted
procedure
Prior art date
Application number
NO872971A
Other languages
English (en)
Other versions
NO872971D0 (no
Inventor
Ellen Myra Berman
Mark James Suto
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO872971D0 publication Critical patent/NO872971D0/no
Publication of NO872971L publication Critical patent/NO872971L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)

Abstract

Forbindelser med formelen. hvor Ri er alkyl med fra et til tre karbonatomer og Rer brom, klor' eller cyano.Fremstilling av forbindelsene samt mellomprodukter ved deres fremstilling er beskrevet.Forbindelsene kan brukes ved fremstilling av trimetraxat og lignende antifolatmidler.
NO872971A 1986-07-17 1987-07-16 FremgangsmŸte ved fremstilling av 5,6-substituerte 2,4-kinazolindiaminer og nye mellomprodukter. NO872971L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/886,463 US4677219A (en) 1986-07-17 1986-07-17 Substituted benzonitriles

Publications (2)

Publication Number Publication Date
NO872971D0 NO872971D0 (no) 1987-07-16
NO872971L true NO872971L (no) 1988-01-18

Family

ID=25389079

Family Applications (1)

Application Number Title Priority Date Filing Date
NO872971A NO872971L (no) 1986-07-17 1987-07-16 FremgangsmŸte ved fremstilling av 5,6-substituerte 2,4-kinazolindiaminer og nye mellomprodukter.

Country Status (16)

Country Link
US (1) US4677219A (no)
EP (1) EP0253396B1 (no)
JP (1) JPS6330474A (no)
KR (1) KR880001615A (no)
AT (1) ATE86984T1 (no)
AU (1) AU591305B2 (no)
CA (1) CA1282078C (no)
DE (1) DE3784795T2 (no)
DK (1) DK368587A (no)
ES (1) ES2053478T3 (no)
FI (1) FI873125A7 (no)
NO (1) NO872971L (no)
NZ (1) NZ221020A (no)
PH (1) PH23781A (no)
PT (1) PT85345B (no)
ZA (1) ZA874651B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4818753A (en) * 1987-09-18 1989-04-04 Sri International Synthesis and method of use for 2, 4 diaminoquinazoline
US4886936A (en) * 1988-08-15 1989-12-12 Ici Americas Inc. Process for the production of ortho-nitrobenzonitriles
GB8910722D0 (en) * 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
IL108630A0 (en) * 1993-02-18 1994-05-30 Fmc Corp Insecticidal substituted 2,4-diaminoquinazolines
US5716960A (en) * 1995-01-13 1998-02-10 U.S. Bioscience Inc. And Individuals Crystalline trimetrexate salts and the process for making the same
US6017922A (en) * 1998-05-18 2000-01-25 U.S. Bioscience, Inc. Thermally stable trimetrexates and processes for producing the same
DE102008022221A1 (de) 2008-05-06 2009-11-12 Universität des Saarlandes Inhibitoren der humanen Aldosteronsynthase CYP11B2
US8541404B2 (en) * 2009-11-09 2013-09-24 Elexopharm Gmbh Inhibitors of the human aldosterone synthase CYP11B2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1345502A (en) * 1916-11-23 1920-07-06 John G Livingston Switch or receptacle box
GB1345502A (en) * 1972-07-06 1974-01-30 Parke Davis & Co Quinazoline compounds and processes for their production
US4900859A (en) * 1987-12-03 1990-02-13 Hoffman-La Roche Inc. Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde

Also Published As

Publication number Publication date
FI873125L (fi) 1988-01-18
DK368587D0 (da) 1987-07-15
DE3784795T2 (de) 1993-06-24
EP0253396A2 (en) 1988-01-20
PT85345B (pt) 1990-04-30
PT85345A (en) 1987-08-01
US4677219A (en) 1987-06-30
FI873125A7 (fi) 1988-01-18
ZA874651B (en) 1989-02-22
CA1282078C (en) 1991-03-26
JPS6330474A (ja) 1988-02-09
ES2053478T3 (es) 1994-08-01
NZ221020A (en) 1990-06-26
KR880001615A (ko) 1988-04-25
FI873125A0 (fi) 1987-07-15
AU591305B2 (en) 1989-11-30
DK368587A (da) 1988-01-18
DE3784795D1 (de) 1993-04-22
PH23781A (en) 1989-11-03
ATE86984T1 (de) 1993-04-15
EP0253396A3 (en) 1989-04-19
AU7501287A (en) 1988-01-21
NO872971D0 (no) 1987-07-16
EP0253396B1 (en) 1993-03-17

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