ATE86984T1 - Verfahren zur herstellung von 5,6-substituierten- 2,4-chinazolindiaminen und zwischenprodukten. - Google Patents
Verfahren zur herstellung von 5,6-substituierten- 2,4-chinazolindiaminen und zwischenprodukten.Info
- Publication number
- ATE86984T1 ATE86984T1 AT87110310T AT87110310T ATE86984T1 AT E86984 T1 ATE86984 T1 AT E86984T1 AT 87110310 T AT87110310 T AT 87110310T AT 87110310 T AT87110310 T AT 87110310T AT E86984 T1 ATE86984 T1 AT E86984T1
- Authority
- AT
- Austria
- Prior art keywords
- quinazolinediamines
- substituted
- preparation
- intermediate products
- trimetrexate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/886,463 US4677219A (en) | 1986-07-17 | 1986-07-17 | Substituted benzonitriles |
| EP87110310A EP0253396B1 (de) | 1986-07-17 | 1987-07-16 | Verfahren zur Herstellung von 5,6-substituierten-2,4-Chinazolindiaminen und Zwischenprodukten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE86984T1 true ATE86984T1 (de) | 1993-04-15 |
Family
ID=25389079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87110310T ATE86984T1 (de) | 1986-07-17 | 1987-07-16 | Verfahren zur herstellung von 5,6-substituierten- 2,4-chinazolindiaminen und zwischenprodukten. |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4677219A (de) |
| EP (1) | EP0253396B1 (de) |
| JP (1) | JPS6330474A (de) |
| KR (1) | KR880001615A (de) |
| AT (1) | ATE86984T1 (de) |
| AU (1) | AU591305B2 (de) |
| CA (1) | CA1282078C (de) |
| DE (1) | DE3784795T2 (de) |
| DK (1) | DK368587A (de) |
| ES (1) | ES2053478T3 (de) |
| FI (1) | FI873125A (de) |
| NO (1) | NO872971L (de) |
| NZ (1) | NZ221020A (de) |
| PH (1) | PH23781A (de) |
| PT (1) | PT85345B (de) |
| ZA (1) | ZA874651B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4818753A (en) * | 1987-09-18 | 1989-04-04 | Sri International | Synthesis and method of use for 2, 4 diaminoquinazoline |
| US4886936A (en) * | 1988-08-15 | 1989-12-12 | Ici Americas Inc. | Process for the production of ortho-nitrobenzonitriles |
| GB8910722D0 (en) * | 1989-05-10 | 1989-06-28 | Smithkline Beckman Intercredit | Compounds |
| IL108630A0 (en) * | 1993-02-18 | 1994-05-30 | Fmc Corp | Insecticidal substituted 2,4-diaminoquinazolines |
| US5716960A (en) * | 1995-01-13 | 1998-02-10 | U.S. Bioscience Inc. And Individuals | Crystalline trimetrexate salts and the process for making the same |
| US6017922A (en) | 1998-05-18 | 2000-01-25 | U.S. Bioscience, Inc. | Thermally stable trimetrexates and processes for producing the same |
| DE102008022221A1 (de) | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| US8541404B2 (en) * | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1345502A (en) * | 1916-11-23 | 1920-07-06 | John G Livingston | Switch or receptacle box |
| GB1345502A (en) * | 1972-07-06 | 1974-01-30 | Parke Davis & Co | Quinazoline compounds and processes for their production |
| US4900859A (en) * | 1987-12-03 | 1990-02-13 | Hoffman-La Roche Inc. | Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde |
-
1986
- 1986-07-17 US US06/886,463 patent/US4677219A/en not_active Expired - Lifetime
-
1987
- 1987-06-26 ZA ZA874651A patent/ZA874651B/xx unknown
- 1987-06-29 CA CA000540861A patent/CA1282078C/en not_active Expired - Fee Related
- 1987-07-01 AU AU75012/87A patent/AU591305B2/en not_active Ceased
- 1987-07-09 NZ NZ221020A patent/NZ221020A/xx unknown
- 1987-07-15 FI FI873125A patent/FI873125A/fi not_active Application Discontinuation
- 1987-07-15 DK DK368587A patent/DK368587A/da not_active Application Discontinuation
- 1987-07-15 PH PH35547A patent/PH23781A/en unknown
- 1987-07-16 AT AT87110310T patent/ATE86984T1/de not_active IP Right Cessation
- 1987-07-16 JP JP62176092A patent/JPS6330474A/ja active Pending
- 1987-07-16 DE DE8787110310T patent/DE3784795T2/de not_active Expired - Fee Related
- 1987-07-16 ES ES87110310T patent/ES2053478T3/es not_active Expired - Lifetime
- 1987-07-16 EP EP87110310A patent/EP0253396B1/de not_active Expired - Lifetime
- 1987-07-16 KR KR1019870007685A patent/KR880001615A/ko not_active IP Right Cessation
- 1987-07-16 PT PT85345A patent/PT85345B/pt not_active IP Right Cessation
- 1987-07-16 NO NO872971A patent/NO872971L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA874651B (en) | 1989-02-22 |
| NZ221020A (en) | 1990-06-26 |
| KR880001615A (ko) | 1988-04-25 |
| NO872971L (no) | 1988-01-18 |
| FI873125A0 (fi) | 1987-07-15 |
| DE3784795T2 (de) | 1993-06-24 |
| EP0253396B1 (de) | 1993-03-17 |
| AU7501287A (en) | 1988-01-21 |
| EP0253396A2 (de) | 1988-01-20 |
| CA1282078C (en) | 1991-03-26 |
| PH23781A (en) | 1989-11-03 |
| EP0253396A3 (en) | 1989-04-19 |
| DK368587D0 (da) | 1987-07-15 |
| PT85345B (pt) | 1990-04-30 |
| US4677219A (en) | 1987-06-30 |
| FI873125A (fi) | 1988-01-18 |
| DK368587A (da) | 1988-01-18 |
| ES2053478T3 (es) | 1994-08-01 |
| NO872971D0 (no) | 1987-07-16 |
| DE3784795D1 (de) | 1993-04-22 |
| JPS6330474A (ja) | 1988-02-09 |
| AU591305B2 (en) | 1989-11-30 |
| PT85345A (en) | 1987-08-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |