NO853255L - Fremgangsmaate for fremstilling av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-benzazepin. - Google Patents
Fremgangsmaate for fremstilling av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-benzazepin.Info
- Publication number
- NO853255L NO853255L NO853255A NO853255A NO853255L NO 853255 L NO853255 L NO 853255L NO 853255 A NO853255 A NO 853255A NO 853255 A NO853255 A NO 853255A NO 853255 L NO853255 L NO 853255L
- Authority
- NO
- Norway
- Prior art keywords
- methyl
- benzazepine
- tetrahydro
- approx
- trichlorobenzene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/647,552 US4541954A (en) | 1984-09-05 | 1984-09-05 | Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO853255L true NO853255L (no) | 1986-03-06 |
Family
ID=24597406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO853255A NO853255L (no) | 1984-09-05 | 1985-08-19 | Fremgangsmaate for fremstilling av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-benzazepin. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4541954A (cg-RX-API-DMAC7.html) |
| EP (1) | EP0174118A3 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS6168469A (cg-RX-API-DMAC7.html) |
| KR (1) | KR860002470A (cg-RX-API-DMAC7.html) |
| AU (1) | AU581918B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1244017A (cg-RX-API-DMAC7.html) |
| DK (1) | DK379985A (cg-RX-API-DMAC7.html) |
| EG (1) | EG17149A (cg-RX-API-DMAC7.html) |
| ES (1) | ES8609266A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI853255A7 (cg-RX-API-DMAC7.html) |
| GR (1) | GR852041B (cg-RX-API-DMAC7.html) |
| HU (1) | HU194181B (cg-RX-API-DMAC7.html) |
| IL (1) | IL76100A0 (cg-RX-API-DMAC7.html) |
| NO (1) | NO853255L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ213141A (cg-RX-API-DMAC7.html) |
| PH (1) | PH20796A (cg-RX-API-DMAC7.html) |
| PT (1) | PT81018B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA856268B (cg-RX-API-DMAC7.html) |
| ZW (1) | ZW13385A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993000811A1 (en) * | 1991-07-01 | 1993-01-21 | The General Hospital Corporation | Invertebrate phenylethanolamine transporter and the use thereof |
| US5401595A (en) * | 1991-12-06 | 1995-03-28 | Yuasa Corporation | Film type battery and layer-built film type battery |
| US6953787B2 (en) | 2002-04-12 | 2005-10-11 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulators |
| EA016558B1 (ru) | 2003-06-17 | 2012-05-30 | Арена Фармасьютикалз, Инк. | Производные бензазепина, используемые для лечения заболеваний, ассоциированных с 5-ht-рецептором |
| SI2332921T1 (sl) | 2003-06-17 | 2016-06-30 | Arena Pharmaceuticals, Inc. | 8-kloro-1-metil-2,3,4,5-tetrahidro-1H-3-benzazapin hidroklorid |
| US8168624B2 (en) | 2004-12-21 | 2012-05-01 | Arena Pharmaceuticals, Inc. | Crystalline forms of (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride |
| EP2111859A1 (en) * | 2004-12-23 | 2009-10-28 | Arena Pharmaceuticals, Inc. | 5HT2C receptor modulator compositions and methods of use |
| JP5199997B2 (ja) * | 2006-04-03 | 2013-05-15 | アリーナ ファーマシューティカルズ， インコーポレイテッド | ８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンズアゼピンおよびこれに関連する中間体を調製するためのプロセス |
| WO2008070111A2 (en) * | 2006-12-05 | 2008-06-12 | Arena Pharmaceuticals, Inc. | Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof |
| CN102015591B (zh) * | 2008-03-04 | 2014-01-29 | 艾尼纳制药公司 | 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法 |
| WO2010148207A2 (en) | 2009-06-18 | 2010-12-23 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| WO2011153206A1 (en) | 2010-06-02 | 2011-12-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of 5-ht2c receptor agonists |
| SG10201506870PA (en) | 2010-09-01 | 2015-10-29 | Arena Pharm Inc | Salts of lorcaserin with optically active acids |
| KR20180094131A (ko) | 2010-09-01 | 2018-08-22 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신장 손상을 갖는 개체에 대한 로카세린의 투여 |
| CN103189360A (zh) | 2010-09-01 | 2013-07-03 | 艾尼纳制药公司 | 5-ht2c激动剂的非吸湿性盐 |
| SG188362A1 (en) | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Modified-release dosage forms of 5-ht2c agonists useful for weight management |
| WO2014058441A1 (en) | 2012-10-09 | 2014-04-17 | Arena Pharmaceuticals, Inc. | Method of weight management |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH481110A (de) * | 1967-02-17 | 1969-11-15 | Geigy Ag J R | Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen |
| GB1118688A (en) * | 1967-02-17 | 1968-07-03 | Scherico Ltd | Novel benzazepines and process for making same |
| US4251660A (en) * | 1978-08-10 | 1981-02-17 | Smithkline Corporation | Method for preparing tetrahydroisoquinolines |
| US4200754A (en) * | 1979-02-02 | 1980-04-29 | Smithkline Corporation | Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline |
| ZA827887B (en) * | 1981-11-27 | 1983-11-30 | Smithkline Beckman Corp | Pharmaceutical compositions and method of producing alpha2 antagonism |
| IE53962B1 (en) * | 1981-11-27 | 1989-04-26 | Smithkline Beckman Corp | 3-benzazepines as alpha-2 antagonists |
| EP0161350A1 (en) * | 1981-11-27 | 1985-11-21 | Smithkline Beckman Corporation | Process for preparing benzazepines |
-
1984
- 1984-09-05 US US06/647,552 patent/US4541954A/en not_active Expired - Fee Related
-
1985
- 1985-08-14 EP EP85305780A patent/EP0174118A3/en not_active Ceased
- 1985-08-15 IL IL76100A patent/IL76100A0/xx unknown
- 1985-08-19 ZA ZA856268A patent/ZA856268B/xx unknown
- 1985-08-19 NO NO853255A patent/NO853255L/no unknown
- 1985-08-19 CA CA000488976A patent/CA1244017A/en not_active Expired
- 1985-08-19 NZ NZ213141A patent/NZ213141A/xx unknown
- 1985-08-19 PH PH32660A patent/PH20796A/en unknown
- 1985-08-20 ES ES546285A patent/ES8609266A1/es not_active Expired
- 1985-08-20 ZW ZW133/85A patent/ZW13385A1/xx unknown
- 1985-08-20 JP JP60183788A patent/JPS6168469A/ja active Pending
- 1985-08-21 HU HU853190A patent/HU194181B/hu unknown
- 1985-08-21 DK DK379985A patent/DK379985A/da not_active Application Discontinuation
- 1985-08-21 AU AU46481/85A patent/AU581918B2/en not_active Ceased
- 1985-08-22 GR GR852041A patent/GR852041B/el unknown
- 1985-08-22 KR KR1019850006061A patent/KR860002470A/ko not_active Withdrawn
- 1985-08-23 PT PT81018A patent/PT81018B/pt unknown
- 1985-08-23 FI FI853255A patent/FI853255A7/fi not_active Application Discontinuation
- 1985-09-04 EG EG545/85A patent/EG17149A/xx active
Also Published As
| Publication number | Publication date |
|---|---|
| AU581918B2 (en) | 1989-03-09 |
| DK379985A (da) | 1986-03-06 |
| ZA856268B (en) | 1986-07-30 |
| ES8609266A1 (es) | 1986-09-01 |
| KR860002470A (ko) | 1986-04-26 |
| ZW13385A1 (en) | 1985-11-20 |
| IL76100A0 (en) | 1985-12-31 |
| JPS6168469A (ja) | 1986-04-08 |
| CA1244017A (en) | 1988-11-01 |
| FI853255L (fi) | 1986-03-06 |
| NZ213141A (en) | 1988-07-28 |
| FI853255A0 (fi) | 1985-08-23 |
| ES546285A0 (es) | 1986-09-01 |
| EP0174118A2 (en) | 1986-03-12 |
| EG17149A (en) | 1989-06-30 |
| AU4648185A (en) | 1986-03-13 |
| EP0174118A3 (en) | 1986-12-30 |
| GR852041B (cg-RX-API-DMAC7.html) | 1985-12-19 |
| DK379985D0 (da) | 1985-08-21 |
| US4541954A (en) | 1985-09-17 |
| PT81018B (en) | 1987-06-24 |
| HU194181B (en) | 1988-01-28 |
| HUT38617A (en) | 1986-06-30 |
| PH20796A (en) | 1987-04-14 |
| FI853255A7 (fi) | 1986-03-06 |
| PT81018A (en) | 1985-09-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO853255L (no) | Fremgangsmaate for fremstilling av 6-klor-n-metyl-2,3,4,5-tetrahydro-1h-3-benzazepin. | |
| US4172074A (en) | Preparation of an antidepressant | |
| US6559319B2 (en) | Synthesis of compounds useful in the manufacture of ketorolac | |
| CA1058615A (en) | Process for benz(f)-2,5-oxazocines | |
| WO1998005657A1 (en) | 2,3-dihydro-1,4-benzothiazepines, their preparation and their use as intermediates | |
| JP2543983B2 (ja) | ４―ジ置換フェニル―１―テトラロン類の製造方法 | |
| US3464977A (en) | 5-(amino-loweralkyl)-4,5-dihydrothieno-(2,3-b)benzothiazepin-4-ones | |
| US4560787A (en) | Process for preparing 10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-one compounds | |
| US5274131A (en) | 2-chloropropionaldehyde trimer and production process thereof | |
| US3428677A (en) | Chemical compounds and methods of preparing same | |
| EP0090203B1 (en) | Process for preparing p.chlorophenoxyacetyl-piperonylpiperazine | |
| CN100558727C (zh) | 喹唑啉生物碱类产品的制备方法 | |
| JP4401167B2 (ja) | 三環式ケトン中間体の合成プロセス | |
| KR880002290B1 (ko) | N-[2-(2-아미노-2-페닐에틸)페닐]-2.2-디메틸프로판아미드의 제조방법 | |
| JPH05178833A (ja) | Ｎ−シアノアセトアミジン誘導体の製造方法 | |
| KR100486320B1 (ko) | 5,11-디히드로-6에이치-디벤즈[비,이]아제핀-6-온의제조방법 | |
| US3329677A (en) | N-benzhydryloxyphthalimides and pryidinealdehyde o-benzhydryloximes | |
| KR100486316B1 (ko) | 5,11-디히드로-6에이치-디벤즈[비,이]아제핀-6-온의새로운 제조방법 | |
| JPS6054948B2 (ja) | α，β↓−不飽和環状脂肪族ケトキシムから芳香族アミンを製造する方法 | |
| EP0370366A2 (en) | Resolution process for benzazepine intermediates | |
| US1930753A (en) | Chlorination of cresidine | |
| US4159381A (en) | 4-(P-Fluorobenzoyl)-1-[3-(p-fluorobenzoyl)propyl]piperidine | |
| US4048169A (en) | 1,3-Bis-(β-ethylhexyl)-5-nitro-5-methyl-hexahydropyrimidine-naphthalene-1,5-disulphonate | |
| JPH0583537B2 (cg-RX-API-DMAC7.html) | ||
| NO772673L (no) | Fremgangsm}te ved fremstilling av d-2-(6-methoxy-2-nafthyl)-propionsyre |