NO850311L - Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater

Info

Publication number
NO850311L
NO850311L NO850311A NO850311A NO850311L NO 850311 L NO850311 L NO 850311L NO 850311 A NO850311 A NO 850311A NO 850311 A NO850311 A NO 850311A NO 850311 L NO850311 L NO 850311L
Authority
NO
Norway
Prior art keywords
carbon atoms
optionally substituted
naphthoquinone
formula
lower alkyl
Prior art date
Application number
NO850311A
Other languages
English (en)
Norwegian (no)
Inventor
Gordon H Jones
Michael C Venuti
John M Young
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO850311L publication Critical patent/NO850311L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
    • C07C50/14—Quinones the quinoid structure being part of a condensed ring system containing two rings with unsaturation outside the ring system, e.g. vitamin K1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/24—Quinones containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/32—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/64—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Organic Insulating Materials (AREA)
  • Luminescent Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Paper (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO850311A 1984-01-27 1985-01-25 Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater NO850311L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57442684A 1984-01-27 1984-01-27

Publications (1)

Publication Number Publication Date
NO850311L true NO850311L (no) 1985-07-29

Family

ID=24296077

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850311A NO850311L (no) 1984-01-27 1985-01-25 Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater

Country Status (15)

Country Link
EP (1) EP0150831B1 (xx)
JP (1) JPS60185745A (xx)
KR (1) KR900007272B1 (xx)
AT (1) ATE36316T1 (xx)
AU (1) AU3809885A (xx)
DE (1) DE3564259D1 (xx)
DK (1) DK35885A (xx)
ES (1) ES539866A0 (xx)
FI (1) FI850325L (xx)
HU (1) HU194533B (xx)
IE (1) IE850174L (xx)
IL (1) IL74162A0 (xx)
NO (1) NO850311L (xx)
NZ (1) NZ210938A (xx)
ZA (1) ZA85623B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE943625C (de) * 1943-06-28 1956-05-24 Ferguson Harry Inc Seitensteuerungseinrichtung fuer ein landwirtschaftliches Schlepperanbaugeraet
US4593120A (en) * 1982-10-27 1986-06-03 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
US4792556A (en) * 1985-09-09 1988-12-20 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
JPS6284046A (ja) * 1985-09-09 1987-04-17 シンテツクス（ユ−・エス・エイ）インコ−ポレイテツド ナフタレン系抗乾癬剤
FI881065A (fi) * 1987-03-09 1988-09-10 Syntex Inc Foerfarande foer framstaellning av naftalenfoereningar anvaendbara vid behandling av psoriasis.
US4786652A (en) * 1987-03-09 1988-11-22 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
US5089657A (en) * 1987-03-11 1992-02-18 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
WO2000008495A2 (en) * 1998-08-06 2000-02-17 University Of Pittsburgh Of The Commonwealth System Of Higher Education Antiproliferative naphthoquinones, derivatives, compositions, and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4229478A (en) * 1978-06-05 1980-10-21 Syntex (U.S.A.) Inc. Naphthaquinone anti-psoriatic agents
US4255405A (en) * 1978-06-05 1981-03-10 Syntex (U.S.A.) Inc. Naphthoquinone anti-psoriatic agents
US4466981A (en) * 1982-10-27 1984-08-21 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
US4593120A (en) * 1982-10-27 1986-06-03 Syntex (U.S.A.) Inc. Naphthalene anti-psoriatic agents
JPH0520420A (ja) * 1991-07-12 1993-01-29 Brother Ind Ltd 図形処理装置

Also Published As

Publication number Publication date
AU3809885A (en) 1985-08-01
EP0150831A2 (en) 1985-08-07
ATE36316T1 (de) 1988-08-15
ZA85623B (en) 1986-08-27
FI850325L (fi) 1985-07-28
IL74162A0 (en) 1985-04-30
DE3564259D1 (en) 1988-09-15
IE850174L (en) 1985-07-27
KR900007272B1 (ko) 1990-10-06
FI850325A0 (fi) 1985-01-25
EP0150831A3 (en) 1985-12-18
KR850005397A (ko) 1985-08-24
HUT36775A (en) 1985-10-28
NZ210938A (en) 1988-04-29
EP0150831B1 (en) 1988-08-10
ES8601089A1 (es) 1985-11-16
ES539866A0 (es) 1985-11-16
JPS60185745A (ja) 1985-09-21
DK35885A (da) 1985-07-28
HU194533B (en) 1988-02-29
DK35885D0 (da) 1985-01-25

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