NO833526L - Fremgangsmaate for fremstilling av guanidinderivater med anti-virus-virkning - Google Patents

Fremgangsmaate for fremstilling av guanidinderivater med anti-virus-virkning

Info

Publication number
NO833526L
NO833526L NO833526A NO833526A NO833526L NO 833526 L NO833526 L NO 833526L NO 833526 A NO833526 A NO 833526A NO 833526 A NO833526 A NO 833526A NO 833526 L NO833526 L NO 833526L
Authority
NO
Norway
Prior art keywords
compound
formula
hydrogen
propoxymethyl
guanine
Prior art date
Application number
NO833526A
Other languages
English (en)
Norwegian (no)
Inventor
Julien P H Verheyden
John C Martin
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO833526L publication Critical patent/NO833526L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/17—Unsaturated ethers containing halogen
    • C07C43/174—Unsaturated ethers containing halogen containing six-membered aromatic rings
    • C07C43/1745—Unsaturated ethers containing halogen containing six-membered aromatic rings having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO833526A 1982-09-30 1983-09-29 Fremgangsmaate for fremstilling av guanidinderivater med anti-virus-virkning NO833526L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43193382A 1982-09-30 1982-09-30
US46427483A 1983-02-07 1983-02-07

Publications (1)

Publication Number Publication Date
NO833526L true NO833526L (no) 1984-04-02

Family

ID=27029273

Family Applications (1)

Application Number Title Priority Date Filing Date
NO833526A NO833526L (no) 1982-09-30 1983-09-29 Fremgangsmaate for fremstilling av guanidinderivater med anti-virus-virkning

Country Status (7)

Country Link
EP (1) EP0105486A3 (de)
AU (1) AU565012B2 (de)
DK (1) DK448983A (de)
ES (4) ES526064A0 (de)
FI (1) FI833504L (de)
NO (1) NO833526L (de)
NZ (1) NZ205802A (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880820A (en) * 1983-06-24 1989-11-14 Merck & Co., Inc. Guanine derivatives
EP0138683A3 (de) * 1983-09-30 1988-01-20 Merck & Co. Inc. Purinderivate, ihre Verwendung in antiviralen Zubereitungen
US4579849A (en) * 1984-04-06 1986-04-01 Merck & Co., Inc. N-alkylguanine acyclonucleosides as antiviral agents
CS264222B1 (en) * 1986-07-18 1989-06-13 Holy Antonin N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods
CN108794477A (zh) * 2018-08-06 2018-11-13 华东师范大学 一种n2取代鸟嘌呤类化合物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4199574A (en) * 1974-09-02 1980-04-22 Burroughs Wellcome Co. Methods and compositions for treating viral infections and guanine acyclic nucleosides
US4347360A (en) * 1980-09-16 1982-08-31 Ens Bio Logicals Inc. Ring open nucleoside analogues
NZ201662A (en) * 1981-08-26 1986-07-11 Merck & Co Inc 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation

Also Published As

Publication number Publication date
ES542299A0 (es) 1986-04-01
ES542297A0 (es) 1986-04-01
ES8507550A1 (es) 1985-09-16
AU1972383A (en) 1984-04-05
ES8605533A1 (es) 1986-04-01
AU565012B2 (en) 1987-09-03
FI833504A7 (fi) 1984-03-31
ES8605520A1 (es) 1986-04-01
FI833504A0 (fi) 1983-09-29
ES8606870A1 (es) 1986-05-16
DK448983A (da) 1984-03-31
ES542298A0 (es) 1986-05-16
EP0105486A3 (de) 1984-05-16
EP0105486A2 (de) 1984-04-18
FI833504L (fi) 1984-03-31
NZ205802A (en) 1986-10-08
ES526064A0 (es) 1985-09-16
DK448983D0 (da) 1983-09-29

Similar Documents

Publication Publication Date Title
EP0074306B1 (de) Antivirale Guaninderivate
FI79851B (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla substituerade 9-(1,3-diacyloxi-2-propoxmetyl) puriner.
EP0066208B1 (de) 9-(1,3-Dihydroxy-2-propoxymethyl)-Guanin als antivirales Mittel
DE69704286T2 (de) Phosphonat-Nukleotid-Verbindungen
EP0369409B1 (de) Carbocyclische Nukleoside und Nukleotide
US4816447A (en) Anti-viral guanine compounds
IE72096B1 (en) 9-purinyl phosphonic acid derivatives
CZ283182B6 (cs) Guaninové deriváty, způsob jejich výroby a farmaceutické prostředky s jejich obsahem
US5532225A (en) Acyclic purine phosphonate nucleotide analogs as antiviral agents, and related synthetic methods
WO1998034603A1 (en) Use of betulin and analogs thereof to treat herpesvirus infection
EP0353955A2 (de) Chemische Verbindungen
EP0138656B1 (de) Zyklische Purin- und Pyrimidin-Acyclonucleosiden, ihre Herstellung und ihre Anwendung in anti-viralen Zusammensetzungen
US4565868A (en) Process for preparing guanine derivatives
NO833526L (no) Fremgangsmaate for fremstilling av guanidinderivater med anti-virus-virkning
EP0105135B1 (de) Substituierte 9-(1-0- oder 3-0-monosubstituierte oder 1,3-di-0-substituierte 1,3-Dihydroxy-2-propoxymethyl)-purine als antivirale Wirkstoffe
AU672994B2 (en) Liponucleotides of seco-nucleosides, their preparation and their use as anti-viral drugs
EP0145739B1 (de) Neue antivirale agenzien
CA1157854A (en) Adenine nucleoside derivatives, their preparation and pharmaceutical compositions containing them
US4603219A (en) 1,3-dibenzyloxy-2-acetoxymethoxypropane, intermediate for 9-(1,3-dihydroxy-2-propoxymethyl)guanine
US5457091A (en) N1-substituted 1H-1,2,3-triazolo[4,5,-D]pyrimidines, a process for their preparation and their use as antiviral agents
JPS5984896A (ja) グアニンのリン酸エステル誘導体
CA1287832C (en) Anti-viral compounds
US5733890A (en) Adenylate analogs as potent anti-herpes virus agents
NO874782L (no) Guaninderivater.
FR2733234A1 (fr) Derives de l'acyclovir comme agents antiviraux