NO802425L - Fremgangsmaate til fremstilling av nye 4-aryl-5,6,7,8-tetrahydropyrazolo (3,4-b) diazepin-1h, 4h-5,7-dioner og legemidler inneholdende disse - Google Patents
Fremgangsmaate til fremstilling av nye 4-aryl-5,6,7,8-tetrahydropyrazolo (3,4-b) diazepin-1h, 4h-5,7-dioner og legemidler inneholdende disseInfo
- Publication number
- NO802425L NO802425L NO802425A NO802425A NO802425L NO 802425 L NO802425 L NO 802425L NO 802425 A NO802425 A NO 802425A NO 802425 A NO802425 A NO 802425A NO 802425 L NO802425 L NO 802425L
- Authority
- NO
- Norway
- Prior art keywords
- group
- tetrahydropyrazolo
- diazepine
- dione
- phenyl
- Prior art date
Links
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- 229910017604 nitric acid Inorganic materials 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 229960005419 nitrogen Drugs 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- GQPLMRYTRLFLPF-UHFFFAOYSA-N nitrous oxide Inorganic materials [O-][N+]#N GQPLMRYTRLFLPF-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 239000012074 organic phase Substances 0.000 description 1
- MUMZUERVLWJKNR-UHFFFAOYSA-N oxoplatinum Chemical compound [Pt]=O MUMZUERVLWJKNR-UHFFFAOYSA-N 0.000 description 1
- 229910052763 palladium Inorganic materials 0.000 description 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N palladium Substances [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 description 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 description 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 description 1
- 239000006187 pill Substances 0.000 description 1
- 229910003446 platinum oxide Inorganic materials 0.000 description 1
- 239000003880 polar aprotic solvent Substances 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 125000004368 propenyl group Chemical group C(=CC)* 0.000 description 1
- JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical compound O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 description 1
- 125000003226 pyrazolyl group Chemical group 0.000 description 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
- 238000006894 reductive elimination reaction Methods 0.000 description 1
- 238000007363 ring formation reaction Methods 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 230000036280 sedation Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- JVBXVOWTABLYPX-UHFFFAOYSA-L sodium dithionite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])=O JVBXVOWTABLYPX-UHFFFAOYSA-L 0.000 description 1
- 239000012312 sodium hydride Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- VCBSMHZNRBWEIJ-UHFFFAOYSA-L trimethyl-[5-[5-(trimethylazaniumyl)pentoxy]pentyl]azanium;dichloride Chemical compound [Cl-].[Cl-].C[N+](C)(C)CCCCCOCCCCC[N+](C)(C)C VCBSMHZNRBWEIJ-UHFFFAOYSA-L 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
- C07D231/40—Acylated on said nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792932835 DE2932835A1 (de) | 1979-08-14 | 1979-08-14 | Neue 4-aryl-5,6,7,8-tetrahydropyrazolo(3,4-b)diazepin-1h,4h-5,7-dione und verfahren zu ihrer darstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO802425L true NO802425L (no) | 1981-02-16 |
Family
ID=6078398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO802425A NO802425L (no) | 1979-08-14 | 1980-08-13 | Fremgangsmaate til fremstilling av nye 4-aryl-5,6,7,8-tetrahydropyrazolo (3,4-b) diazepin-1h, 4h-5,7-dioner og legemidler inneholdende disse |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4302468A (es) |
| EP (2) | EP0024038B1 (es) |
| JP (1) | JPS5630977A (es) |
| AR (1) | AR226860A1 (es) |
| AT (2) | ATE3040T1 (es) |
| AU (1) | AU535884B2 (es) |
| CA (1) | CA1151645A (es) |
| CS (4) | CS223847B2 (es) |
| DD (3) | DD159699A5 (es) |
| DE (3) | DE2932835A1 (es) |
| DK (1) | DK350180A (es) |
| ES (4) | ES494143A0 (es) |
| FI (1) | FI802536A (es) |
| GR (1) | GR69798B (es) |
| HU (1) | HU180163B (es) |
| IL (1) | IL60828A (es) |
| NO (1) | NO802425L (es) |
| NZ (1) | NZ194633A (es) |
| PH (1) | PH18209A (es) |
| PT (1) | PT71692B (es) |
| ZA (1) | ZA804959B (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198436A (en) * | 1989-10-17 | 1993-03-30 | Ellinwood Jr Everett H | Intraoral dosing method of administering trifluorobenzodiazepines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3558605A (en) * | 1969-05-14 | 1971-01-26 | Parke Davis & Co | Pyrazolo(3,4-e)(1,4)diazepin-7-(1h)-one compounds |
| AT325052B (de) * | 1972-12-07 | 1975-10-10 | Degussa | Verfahren zur herstellung von neuen 6-azabenzo-1,5-diazepinen und ihren salzen |
-
1979
- 1979-08-14 DE DE19792932835 patent/DE2932835A1/de not_active Withdrawn
-
1980
- 1980-08-07 AT AT80104654T patent/ATE3040T1/de not_active IP Right Cessation
- 1980-08-07 AT AT81110770T patent/ATE5536T1/de not_active IP Right Cessation
- 1980-08-07 DE DE8181110770T patent/DE2966484D1/de not_active Expired
- 1980-08-07 EP EP80104654A patent/EP0024038B1/de not_active Expired
- 1980-08-07 EP EP81110770A patent/EP0050376B1/de not_active Expired
- 1980-08-07 DE DE8080104654T patent/DE3062746D1/de not_active Expired
- 1980-08-08 ES ES494143A patent/ES494143A0/es active Granted
- 1980-08-08 ES ES494142A patent/ES494142A0/es active Granted
- 1980-08-08 ES ES494141A patent/ES8103746A1/es not_active Expired
- 1980-08-08 ES ES494144A patent/ES494144A0/es active Granted
- 1980-08-12 NZ NZ194633A patent/NZ194633A/xx unknown
- 1980-08-12 DD DD80230827A patent/DD159699A5/de unknown
- 1980-08-12 PH PH24435A patent/PH18209A/en unknown
- 1980-08-12 IL IL60828A patent/IL60828A/xx unknown
- 1980-08-12 FI FI802536A patent/FI802536A/fi not_active Application Discontinuation
- 1980-08-12 AR AR282129A patent/AR226860A1/es active
- 1980-08-12 US US06/177,411 patent/US4302468A/en not_active Expired - Lifetime
- 1980-08-12 PT PT71692A patent/PT71692B/pt unknown
- 1980-08-12 DD DD80223270A patent/DD152936A5/de unknown
- 1980-08-12 GR GR62647A patent/GR69798B/el unknown
- 1980-08-13 CS CS817966A patent/CS223847B2/cs unknown
- 1980-08-13 AU AU61423/80A patent/AU535884B2/en not_active Ceased
- 1980-08-13 ZA ZA00804959A patent/ZA804959B/xx unknown
- 1980-08-13 HU HU80802017A patent/HU180163B/hu unknown
- 1980-08-13 DK DK350180A patent/DK350180A/da not_active Application Discontinuation
- 1980-08-13 NO NO802425A patent/NO802425L/no unknown
- 1980-08-13 CA CA000358165A patent/CA1151645A/en not_active Expired
- 1980-08-13 CS CS817965A patent/CS223846B2/cs unknown
- 1980-08-13 CS CS805580A patent/CS223833B2/cs unknown
- 1980-08-13 CS CS817964A patent/CS223845B2/cs unknown
- 1980-08-14 JP JP11225480A patent/JPS5630977A/ja active Pending
-
1981
- 1981-06-11 DD DD81230731A patent/DD159640A5/de unknown
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