NO771195L - Vandig l¦sning og fremstilling derav. - Google Patents
Vandig l¦sning og fremstilling derav.Info
- Publication number
- NO771195L NO771195L NO771195A NO771195A NO771195L NO 771195 L NO771195 L NO 771195L NO 771195 A NO771195 A NO 771195A NO 771195 A NO771195 A NO 771195A NO 771195 L NO771195 L NO 771195L
- Authority
- NO
- Norway
- Prior art keywords
- parts
- ipronidazole
- volume
- solution
- formal
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title claims description 5
- NTAFJUSDNOSFFY-UHFFFAOYSA-N Ipronidazole Chemical compound CC(C)C1=NC=C([N+]([O-])=O)N1C NTAFJUSDNOSFFY-UHFFFAOYSA-N 0.000 claims description 27
- 229950000107 ipronidazole Drugs 0.000 claims description 26
- 239000000243 solution Substances 0.000 claims description 18
- MNQZXJOMYWMBOU-UHFFFAOYSA-N glyceraldehyde Chemical compound OCC(O)C=O MNQZXJOMYWMBOU-UHFFFAOYSA-N 0.000 claims description 15
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- 239000007864 aqueous solution Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 239000012153 distilled water Substances 0.000 description 5
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 239000002253 acid Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 235000011187 glycerol Nutrition 0.000 description 3
- 150000003839 salts Chemical class 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 2
- 241000282898 Sus scrofa Species 0.000 description 2
- 239000000654 additive Substances 0.000 description 2
- 239000003708 ampul Substances 0.000 description 2
- CZBZUDVBLSSABA-UHFFFAOYSA-N butylated hydroxyanisole Chemical compound COC1=CC=C(O)C(C(C)(C)C)=C1.COC1=CC=C(O)C=C1C(C)(C)C CZBZUDVBLSSABA-UHFFFAOYSA-N 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- UEUXEKPTXMALOB-UHFFFAOYSA-J tetrasodium;2-[2-[bis(carboxylatomethyl)amino]ethyl-(carboxylatomethyl)amino]acetate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O UEUXEKPTXMALOB-UHFFFAOYSA-J 0.000 description 2
- VCKSNYNNVSOWEE-UHFFFAOYSA-N 1,3-dioxan-5-ol Chemical compound OC1COCOC1 VCKSNYNNVSOWEE-UHFFFAOYSA-N 0.000 description 1
- BOHGAOWOIJMTPZ-UHFFFAOYSA-N 1,3-dioxolan-4-ylmethanol Chemical compound OCC1COCO1 BOHGAOWOIJMTPZ-UHFFFAOYSA-N 0.000 description 1
- ODJQKYXPKWQWNK-UHFFFAOYSA-N 3,3'-Thiobispropanoic acid Chemical compound OC(=O)CCSCCC(O)=O ODJQKYXPKWQWNK-UHFFFAOYSA-N 0.000 description 1
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
- 239000003490 Thiodipropionic acid Substances 0.000 description 1
- LNTHITQWFMADLM-UHFFFAOYSA-N anhydrous gallic acid Natural products OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000007859 condensation product Substances 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940074391 gallic acid Drugs 0.000 description 1
- 235000004515 gallic acid Nutrition 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000000574 octyl gallate Substances 0.000 description 1
- 235000010387 octyl gallate Nutrition 0.000 description 1
- NRPKURNSADTHLJ-UHFFFAOYSA-N octyl gallate Chemical compound CCCCCCCCOC(=O)C1=CC(O)=C(O)C(O)=C1 NRPKURNSADTHLJ-UHFFFAOYSA-N 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 239000000473 propyl gallate Substances 0.000 description 1
- 235000010388 propyl gallate Nutrition 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 235000019303 thiodipropionic acid Nutrition 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Inspection Of Paper Currency And Valuable Securities (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT243476A AT345607B (de) | 1976-04-05 | 1976-04-05 | Verfahren zur herstellung einer stabilen waesserigen ipronidazol-loesung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO771195L true NO771195L (no) | 1977-10-06 |
Family
ID=3534277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO771195A NO771195L (no) | 1976-04-05 | 1977-04-04 | Vandig l¦sning og fremstilling derav. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4089968A (fr) |
| AR (1) | AR211953A1 (fr) |
| AT (1) | AT345607B (fr) |
| AU (1) | AU510536B2 (fr) |
| CA (1) | CA1080621A (fr) |
| FR (1) | FR2347354A1 (fr) |
| GB (1) | GB1563656A (fr) |
| IT (1) | IT1143636B (fr) |
| NO (1) | NO771195L (fr) |
| NZ (1) | NZ183754A (fr) |
| SE (1) | SE7703930L (fr) |
| ZA (1) | ZA771895B (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1266473A3 (ru) * | 1981-08-21 | 1986-10-23 | Мэй Энд Бейкер Лимитед (Фирма) | Способ предотвращени роста анаэробных сульфатвосстанавливающих бактерий |
| BR9405079A (pt) * | 1994-01-10 | 1995-09-26 | Santiago Abelardo Bojali Jaber | Produto químico antiamebiano e antiprotozário e processo para sua obtenção |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3634446A (en) * | 1969-10-06 | 1972-01-11 | Hoffmann La Roche | 1-methyl-2-isopropyl-5-nitroimidazole and water soluble salts thereof |
-
1976
- 1976-04-05 AT AT243476A patent/AT345607B/de not_active IP Right Cessation
-
1977
- 1977-02-10 IT IT20159/77A patent/IT1143636B/it active
- 1977-03-15 AR AR266860A patent/AR211953A1/es active
- 1977-03-22 US US05/779,977 patent/US4089968A/en not_active Expired - Lifetime
- 1977-03-29 ZA ZA00771895A patent/ZA771895B/xx unknown
- 1977-03-30 FR FR7709479A patent/FR2347354A1/fr active Granted
- 1977-03-31 NZ NZ183754A patent/NZ183754A/xx unknown
- 1977-04-01 AU AU23893/77A patent/AU510536B2/en not_active Expired
- 1977-04-04 CA CA275,520A patent/CA1080621A/fr not_active Expired
- 1977-04-04 SE SE7703930A patent/SE7703930L/xx unknown
- 1977-04-04 GB GB14102/77A patent/GB1563656A/en not_active Expired
- 1977-04-04 NO NO771195A patent/NO771195L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATA243476A (de) | 1977-12-15 |
| ZA771895B (en) | 1978-03-29 |
| GB1563656A (en) | 1980-03-26 |
| US4089968A (en) | 1978-05-16 |
| AU510536B2 (en) | 1980-07-03 |
| AT345607B (de) | 1978-09-25 |
| SE7703930L (sv) | 1977-10-06 |
| AR211953A1 (es) | 1978-04-14 |
| NZ183754A (en) | 1980-03-05 |
| AU2389377A (en) | 1978-10-05 |
| CA1080621A (fr) | 1980-07-01 |
| IT1143636B (it) | 1986-10-22 |
| FR2347354B1 (fr) | 1981-11-27 |
| FR2347354A1 (fr) | 1977-11-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR100212942B1 (ko) | 수성 리스페리돈 제제 | |
| US5350769A (en) | Antiinflammatory gel preparation | |
| DK175238B1 (da) | Vandige steroidformuleringer, fremgangsmåde til fremstilling deraf samt anvendelse af sådanne steroidformuleringer til fremstilling af et medikament til behandling af den nasale mucosa | |
| US4420471A (en) | Citrus flavored mouthwash formulation method | |
| EP2470178B1 (fr) | Composition pharmaceutique antimycotique | |
| EP1825855B1 (fr) | Produit contenant de la prostaglandine dont la molecule comporte un atome de fluor | |
| NO153478B (no) | Munn- og tannpleiemidler med stabiliserte tinnsalter. | |
| EA008908B1 (ru) | Инъецируемый жидкий состав парацетамола | |
| US5422102A (en) | Antiinflammatory and analgesic gel preparation | |
| JP3659801B2 (ja) | トラニラスト水溶液製剤 | |
| JPH0696533B2 (ja) | キノロンカルボン酸の水性組成物 | |
| NO771195L (no) | Vandig l¦sning og fremstilling derav. | |
| JPS6351341A (ja) | アズレン含有液剤 | |
| EP0010437A2 (fr) | Solution stable d'érythromycine et procédé pour sa préparation | |
| JP3733546B2 (ja) | アズレン水性液剤 | |
| JPS615011A (ja) | 安定なビタミンｅの可溶化液 | |
| JP2000007561A (ja) | 塩酸アンブロキソール水溶液製剤 | |
| ITMI20071573A1 (it) | Composizione farmaceutica liquida stabile a base di trazodone | |
| JPH03109326A (ja) | フレロキサシン点眼液 | |
| HU179989B (en) | Process for preparing pharmacological compositions containing r-/+/-1-/1-phenyl-ethyl/-1h-imidazol-5-carboxylic acid ethyl ester for intravenous administration | |
| JP2536173B2 (ja) | 注射剤 | |
| DK163798B (da) | Fremgangsmaade til fremstilling af klare, vandige geler ved omgivelsernes temperatur samt saaledes fremstillet, vandigt middel indeholdende en antihelmintisk forbindelse | |
| JPS63297322A (ja) | グアイアズレンスルホン酸ナトリウム配合の安定な点眼剤の製造法 | |
| JPS59219218A (ja) | 局所用作用持続組成物 | |
| GB2185887A (en) | Temazepam composition |