NO339187B1 - Amyloid skanning som en surrogatmarkør for anti-amyloide behandlingsformers effektivitet - Google Patents
Amyloid skanning som en surrogatmarkør for anti-amyloide behandlingsformers effektivitet Download PDFInfo
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- NO339187B1 NO339187B1 NO20070593A NO20070593A NO339187B1 NO 339187 B1 NO339187 B1 NO 339187B1 NO 20070593 A NO20070593 A NO 20070593A NO 20070593 A NO20070593 A NO 20070593A NO 339187 B1 NO339187 B1 NO 339187B1
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- amyloid
- patient
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58448704P | 2004-07-02 | 2004-07-02 | |
| PCT/US2005/023617 WO2006014381A2 (en) | 2004-07-02 | 2005-07-01 | Use of thioflavin radiolabeled derivatives in amyloid imaging gor assessing anti-amyloid therapies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20070593L NO20070593L (no) | 2007-03-27 |
| NO339187B1 true NO339187B1 (no) | 2016-11-14 |
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|---|---|---|---|
| NO20070593A NO339187B1 (no) | 2004-07-02 | 2007-01-31 | Amyloid skanning som en surrogatmarkør for anti-amyloide behandlingsformers effektivitet |
Country Status (16)
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| EP (1) | EP1771208B1 (pt-PT) |
| JP (1) | JP2008505115A (pt-PT) |
| CN (2) | CN101137397A (pt-PT) |
| AU (1) | AU2005270026A1 (pt-PT) |
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| CA (2) | CA2830939C (pt-PT) |
| CY (1) | CY1114644T1 (pt-PT) |
| DK (1) | DK1771208T3 (pt-PT) |
| ES (1) | ES2427963T3 (pt-PT) |
| NO (1) | NO339187B1 (pt-PT) |
| PL (1) | PL1771208T3 (pt-PT) |
| PT (1) | PT1771208E (pt-PT) |
| RU (1) | RU2007104107A (pt-PT) |
| SI (1) | SI1771208T1 (pt-PT) |
| WO (1) | WO2006014381A2 (pt-PT) |
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| US20080050367A1 (en) | 1998-04-07 | 2008-02-28 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| TWI239847B (en) | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| PL215711B1 (pl) * | 2000-08-24 | 2014-01-31 | Univ Pittsburgh | Nowe zwiazki pochodne tioflawiny, sposób syntezy zwiazków i ich zastosowanie, kompozycja farmaceutyczna zawierajaca zwiazki i zastosowanie kompozycji |
| US7270800B2 (en) * | 2000-08-24 | 2007-09-18 | University Of Pittsburgh | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| WO2004069182A2 (en) * | 2003-02-01 | 2004-08-19 | Neuralab Limited | Active immunization to generate antibodies to soluble a-beta |
| US8236282B2 (en) | 2003-08-22 | 2012-08-07 | University of Pittsburgh—of the Commonwealth System of Higher Education | Benzothiazole derivative compounds, compositions and uses |
| WO2006066089A1 (en) | 2004-12-15 | 2006-06-22 | Neuralab Limited | Humanized amyloid beta antibodies for use in improving cognition |
| GB0516564D0 (en) * | 2005-08-12 | 2005-09-21 | Ge Healthcare Ltd | Fluorination process |
| WO2007035405A2 (en) * | 2005-09-16 | 2007-03-29 | University Of Pittsburgh | In-vivo and in-vitro method for detecting amyloid deposits having at least one amyloidogenic protein |
| US8784810B2 (en) | 2006-04-18 | 2014-07-22 | Janssen Alzheimer Immunotherapy | Treatment of amyloidogenic diseases |
| US7700616B2 (en) | 2006-05-08 | 2010-04-20 | Molecular Neuroimaging, Llc. | Compounds and amyloid probes thereof for therapeutic and imaging uses |
| TW200813035A (en) | 2006-06-19 | 2008-03-16 | Astrazeneca Ab | Novel heteroaryl substituted benzoxazoles |
| CN101293878B (zh) * | 2007-04-25 | 2010-12-15 | 中国科学院上海应用物理研究所 | 苯并噻唑苯胺类化合物及其制备方法和应用 |
| PL2182983T3 (pl) * | 2007-07-27 | 2014-10-31 | Janssen Alzheimer Immunotherap | Leczenie chorób amyloidowych z wykorzystaniem humanizowanych przeciwciał specyficznych względem Abeta |
| WO2009027452A2 (en) * | 2007-08-30 | 2009-03-05 | Ge Healthcare Limited | Radiopharmaceutical composition |
| JO3076B1 (ar) | 2007-10-17 | 2017-03-15 | Janssen Alzheimer Immunotherap | نظم العلاج المناعي المعتمد على حالة apoe |
| JP5603855B2 (ja) | 2008-04-04 | 2014-10-08 | アビッド レディオファーマシューティカルズ、インク． | 神経変成疾患の放射性薬剤による画像化 |
| RU2518892C2 (ru) * | 2008-09-23 | 2014-06-10 | Виста Лабораториз Лтд. | Лиганды для агрегированных молекул тау-белка |
| US9067981B1 (en) | 2008-10-30 | 2015-06-30 | Janssen Sciences Ireland Uc | Hybrid amyloid-beta antibodies |
| WO2010053218A1 (en) * | 2008-11-06 | 2010-05-14 | Snu R&Db Foundation | Fluorinated benzothiazole derivatives, preparation method thereof and imaging agent for diagnosing altzheimer's disease using the same |
| JP2013521233A (ja) * | 2010-02-25 | 2013-06-10 | ヤンセン アルツハイマー イミュノセラピー | Ａβを標的とする免疫療法のＰＥＴモニタリング |
| WO2014004664A2 (en) * | 2012-06-27 | 2014-01-03 | Mayo Foundation For Medical Education And Research | Treatment of meningiomas using phenylbenzothiazole, stilbene, biphenylalkyne, or pyridine derivatives |
| US9422286B2 (en) | 2014-01-27 | 2016-08-23 | Washington University | Metal-binding bifunctional compounds as diagnostic agents for Alzheimer's disease |
| AU2016308189B2 (en) * | 2015-08-18 | 2021-03-11 | The Regents Of The University Of California | Nitroxide containing amyloid binding agents for imaging and therapeutic uses |
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| WO2002016333A2 (en) * | 2000-08-24 | 2002-02-28 | University Of Pittsburgh | Thioflavin derivatives and their use in diagnosis and theraphy of alzheimer's disease |
| WO2002085903A2 (en) * | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| WO2003068269A1 (en) * | 2002-02-13 | 2003-08-21 | Amersham Plc | Benzothiazole derivatives for in vivo imaging of amyloid plaques |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US20030092003A1 (en) * | 1999-12-29 | 2003-05-15 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for the treatment of Alzheimer's disease |
| US7270800B2 (en) * | 2000-08-24 | 2007-09-18 | University Of Pittsburgh | Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition |
| GB0130305D0 (en) | 2001-12-19 | 2002-02-06 | Amersham Plc | Compounds for imaging alzheimers disease |
| CA2438032C (en) | 2003-03-14 | 2013-05-07 | University Of Pittsburgh | Benzothiazole derivative compounds, compositions and uses |
| GB0307855D0 (en) | 2003-04-04 | 2003-05-14 | Novartis Ag | Organic compounds |
| BRPI0512932A (pt) * | 2004-07-02 | 2008-04-15 | Univ Pittsburgh | compostos e métodos de identificação e de diagnóstico de paciente como prodrÈmico para doença associada com a deposição amilóide |
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- 2005-07-01 WO PCT/US2005/023617 patent/WO2006014381A2/en active Application Filing
- 2005-07-01 DK DK05787557.7T patent/DK1771208T3/da active
- 2005-07-01 SI SI200531765T patent/SI1771208T1/sl unknown
- 2005-07-01 ES ES05787557T patent/ES2427963T3/es active Active
- 2005-07-01 CN CNA2005800263010A patent/CN101137397A/zh active Pending
- 2005-07-01 AU AU2005270026A patent/AU2005270026A1/en not_active Abandoned
- 2005-07-01 PT PT57875577T patent/PT1771208E/pt unknown
- 2005-07-01 US US11/666,083 patent/US8147798B2/en active Active
- 2005-07-01 CN CN2012104014697A patent/CN102973954A/zh active Pending
- 2005-07-01 JP JP2007519500A patent/JP2008505115A/ja active Pending
- 2005-07-01 CA CA2830939A patent/CA2830939C/en active Active
- 2005-07-01 EP EP05787557.7A patent/EP1771208B1/en active Active
- 2005-07-01 CA CA2587248A patent/CA2587248C/en active Active
- 2005-07-01 RU RU2007104107/04A patent/RU2007104107A/ru not_active Application Discontinuation
- 2005-07-01 BR BRPI0512893A patent/BRPI0512893B8/pt active IP Right Grant
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2007
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2013
- 2013-09-10 CY CY20131100776T patent/CY1114644T1/el unknown
- 2013-10-09 US US14/050,018 patent/US20140105820A1/en not_active Abandoned
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| WO2002016333A2 (en) * | 2000-08-24 | 2002-02-28 | University Of Pittsburgh | Thioflavin derivatives and their use in diagnosis and theraphy of alzheimer's disease |
| WO2002085903A2 (en) * | 2001-04-23 | 2002-10-31 | The Trustees Of The University Of Pennsylvania | Amyloid plaque aggregation inhibitors and diagnostic imaging agents |
| WO2003068269A1 (en) * | 2002-02-13 | 2003-08-21 | Amersham Plc | Benzothiazole derivatives for in vivo imaging of amyloid plaques |
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Also Published As
| Publication number | Publication date |
|---|---|
| SI1771208T1 (sl) | 2013-10-30 |
| US20130045164A1 (en) | 2013-02-21 |
| CN102973954A (zh) | 2013-03-20 |
| US20140105820A1 (en) | 2014-04-17 |
| WO2006014381A2 (en) | 2006-02-09 |
| ES2427963T3 (es) | 2013-11-05 |
| CA2587248C (en) | 2014-01-07 |
| EP1771208A2 (en) | 2007-04-11 |
| US8343457B2 (en) | 2013-01-01 |
| BRPI0512893A (pt) | 2008-04-15 |
| RU2007104107A (ru) | 2008-08-10 |
| US8147798B2 (en) | 2012-04-03 |
| CA2830939C (en) | 2017-02-28 |
| NO20070593L (no) | 2007-03-27 |
| WO2006014381A9 (en) | 2006-04-13 |
| PT1771208E (pt) | 2013-09-24 |
| WO2006014381A3 (en) | 2007-01-18 |
| BRPI0512893B1 (pt) | 2019-12-24 |
| CA2587248A1 (en) | 2006-02-09 |
| DK1771208T3 (da) | 2013-09-02 |
| CA2830939A1 (en) | 2006-02-09 |
| CY1114644T1 (el) | 2016-10-05 |
| PL1771208T3 (pl) | 2013-11-29 |
| AU2005270026A1 (en) | 2006-02-09 |
| US20080219931A1 (en) | 2008-09-11 |
| EP1771208B1 (en) | 2013-06-19 |
| BRPI0512893B8 (pt) | 2021-07-27 |
| US8580229B2 (en) | 2013-11-12 |
| US20120177572A1 (en) | 2012-07-12 |
| JP2008505115A (ja) | 2008-02-21 |
| CN101137397A (zh) | 2008-03-05 |
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