NO330924B1 - Isolert antistoff eller antistoffragment, immunokonjugat, anvendelse av et immunokonjugat, en terapeutisk effektiv mengde av et immunokonjugat eller et antistoff eller antistoffragment for fremstilling av preparater henholdsvis for selektiv odeleggelse av celler, behandling av en sykdomstilstand eller diagnostisering av metastaser eller prostatakreft, samt pavisningsmetode. - Google Patents

Isolert antistoff eller antistoffragment, immunokonjugat, anvendelse av et immunokonjugat, en terapeutisk effektiv mengde av et immunokonjugat eller et antistoff eller antistoffragment for fremstilling av preparater henholdsvis for selektiv odeleggelse av celler, behandling av en sykdomstilstand eller diagnostisering av metastaser eller prostatakreft, samt pavisningsmetode.

Info

Publication number
NO330924B1
NO330924B1 NO20022836A NO20022836A NO330924B1 NO 330924 B1 NO330924 B1 NO 330924B1 NO 20022836 A NO20022836 A NO 20022836A NO 20022836 A NO20022836 A NO 20022836A NO 330924 B1 NO330924 B1 NO 330924B1
Authority
NO
Norway
Prior art keywords
immunoconjugate
antibody
antibody fragment
diagnosis
metastasis
Prior art date
Application number
NO20022836A
Other languages
English (en)
Norwegian (no)
Other versions
NO20022836L (no
NO20022836D0 (no
Inventor
Richard Harkins
Deborah Parkes
Gordon Parry
Douglas W Schneider
Renate Steinbrecher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO20022836D0 publication Critical patent/NO20022836D0/no
Publication of NO20022836L publication Critical patent/NO20022836L/no
Publication of NO330924B1 publication Critical patent/NO330924B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
NO20022836A 1999-12-16 2002-06-14 Isolert antistoff eller antistoffragment, immunokonjugat, anvendelse av et immunokonjugat, en terapeutisk effektiv mengde av et immunokonjugat eller et antistoff eller antistoffragment for fremstilling av preparater henholdsvis for selektiv odeleggelse av celler, behandling av en sykdomstilstand eller diagnostisering av metastaser eller prostatakreft, samt pavisningsmetode. NO330924B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17237099P 1999-12-16 1999-12-16
US09/732,357 US6682902B2 (en) 1999-12-16 2000-12-07 DNA encoding a novel RG1 polypeptide
PCT/US2000/033901 WO2001044291A2 (en) 1999-12-16 2000-12-15 Polynucleotid encoding the rg1 polypeptide

Publications (3)

Publication Number Publication Date
NO20022836D0 NO20022836D0 (no) 2002-06-14
NO20022836L NO20022836L (no) 2002-08-15
NO330924B1 true NO330924B1 (no) 2011-08-22

Family

ID=26868022

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20022836A NO330924B1 (no) 1999-12-16 2002-06-14 Isolert antistoff eller antistoffragment, immunokonjugat, anvendelse av et immunokonjugat, en terapeutisk effektiv mengde av et immunokonjugat eller et antistoff eller antistoffragment for fremstilling av preparater henholdsvis for selektiv odeleggelse av celler, behandling av en sykdomstilstand eller diagnostisering av metastaser eller prostatakreft, samt pavisningsmetode.

Country Status (32)

Country Link
US (5) US6682902B2 (ko)
EP (2) EP1237915B1 (ko)
JP (1) JP4979867B2 (ko)
KR (1) KR100752434B1 (ko)
CN (1) CN1297566C (ko)
AT (1) ATE440862T1 (ko)
AU (1) AU784674B2 (ko)
BG (1) BG65898B1 (ko)
BR (1) BR0017022A (ko)
CA (1) CA2394574A1 (ko)
CZ (1) CZ299232B6 (ko)
DE (1) DE60042836D1 (ko)
DK (1) DK1237915T3 (ko)
EE (1) EE05293B1 (ko)
ES (1) ES2331106T3 (ko)
HR (1) HRP20020549B1 (ko)
HU (1) HU229001B1 (ko)
IL (2) IL150115A0 (ko)
LT (1) LT5046B (ko)
ME (1) MEP37808A (ko)
MX (1) MXPA02005914A (ko)
NO (1) NO330924B1 (ko)
NZ (1) NZ519598A (ko)
PL (1) PL207634B1 (ko)
PT (1) PT1237915E (ko)
RO (1) RO122543B1 (ko)
RS (1) RS50831B (ko)
RU (1) RU2283130C2 (ko)
SI (2) SI21140A (ko)
SK (2) SK288147B6 (ko)
WO (1) WO2001044291A2 (ko)
ZA (1) ZA200205638B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1251139A3 (en) * 1998-04-08 2002-12-18 Genentech, Inc. Human mindin-like protein and nucleic acids encoding it
US20020161199A1 (en) * 1998-04-08 2002-10-31 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6960433B1 (en) 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
US20070031901A1 (en) * 1999-03-08 2007-02-08 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6682902B2 (en) * 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide
NZ544911A (en) 2003-07-22 2008-12-24 Schering Ag RG1 antibodies and uses thereof
US7294704B2 (en) 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
TWI438207B (zh) * 2007-02-21 2014-05-21 Oncotherapy Science Inc 表現腫瘤相關抗原之癌症的胜肽疫苗
EA201000921A1 (ru) * 2007-11-30 2010-12-30 Бристол-Маерс Сквибб Компани Конъюгаты антител против rg-1
TW201008574A (en) 2008-08-19 2010-03-01 Oncotherapy Science Inc INHBB epitope peptides and vaccines containing the same
CN102346184B (zh) * 2010-08-03 2014-03-26 中国人民解放军军事医学科学院生物工程研究所 Spon2的新用途
DE102012016127A1 (de) 2011-08-31 2013-02-28 Daniel Elias Bioaktive, regenerative Mischung zur Herstellung eines Ergänzungsnahrungsmittels

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657760A (en) 1979-03-20 1987-04-14 Ortho Pharmaceutical Corporation Methods and compositions using monoclonal antibody to human T cells
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5206344A (en) 1985-06-26 1993-04-27 Cetus Oncology Corporation Interleukin-2 muteins and polymer conjugation thereof
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4831175A (en) * 1986-09-05 1989-05-16 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US5246692A (en) * 1986-09-05 1993-09-21 The United States Of America As Represented By The Secretary Of Health And Human Services Backbone polysubstituted chelates for forming a metal chelate-protein conjugate
US4987071A (en) 1986-12-03 1991-01-22 University Patents, Inc. RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
US5437994A (en) 1989-06-15 1995-08-01 Regents Of The University Of Michigan Method for the ex vivo replication of stem cells, for the optimization of hematopoietic progenitor cell cultures, and for increasing the metabolism, GM-CSF secretion and/or IL-6 secretion of human stromal cells
US5399493A (en) 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
US5225212A (en) 1989-10-20 1993-07-06 Liposome Technology, Inc. Microreservoir liposome composition and method
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US5877397A (en) 1990-08-29 1999-03-02 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
EP0814159B1 (en) 1990-08-29 2005-07-27 GenPharm International, Inc. Transgenic mice capable of producing heterologous antibodies
AU687001B2 (en) 1992-05-14 1998-02-19 Ribozyme Pharmaceuticals, Inc. Method and reagent for inhibiting cancer development
US5871969A (en) 1996-02-12 1999-02-16 Human Genome Sciences, Inc. Nucleic acids encoding human neuronal attachment factor-1
US6177244B1 (en) 1996-05-10 2001-01-23 Beth Israel Deaconess Medical Center Inc. NPG-1 gene that is differentially expressed in prostate tumors
US5804382A (en) 1996-05-10 1998-09-08 Beth Israel Deaconess Medical Center, Inc. Methods for identifying differentially expressed genes and differences between genomic nucleic acid sequences
US6287777B1 (en) * 1996-05-10 2001-09-11 Beth Israel Deaconess Medical Center NPG-1 gene that is differentially expressed in prostate tumors
JP3494529B2 (ja) * 1996-06-06 2004-02-09 Ykk株式会社 一体成形面ファスナー
WO1998008381A1 (en) * 1996-08-26 1998-03-05 University Of Washington Therapeutic and diagnostic applications of perlecan domain i splice variants
AU6961398A (en) 1997-04-10 1998-10-30 Zymogenetics Inc. Secreted f-spondin homologs
AU735444B2 (en) * 1997-05-06 2001-07-05 Human Genome Sciences, Inc. (Enterococcus faecalis) polynucleotides and polypeptides
WO1998050073A1 (en) 1997-05-09 1998-11-12 Smithkline Beecham Corporation Integrin ligand, human mindin
PT1490386E (pt) 1998-03-10 2008-11-24 Genentech Inc Novos polipéptidos e ácidos nucleicos que os codificam
US6166176A (en) * 1998-03-17 2000-12-26 Immvarx, Inc. Cancer marker protein and peptides thereof
US6960433B1 (en) * 1998-10-19 2005-11-01 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating prostate cancer
EP1126877A4 (en) 1998-10-19 2003-05-28 Diadexus Inc METHOD OF DIAGNOSIS, MONITORING, STADIUM CLASSIFICATION, VISUALIZATION AND TREATMENT OF PROSTATE CANCER
EE05627B1 (et) * 1998-12-23 2013-02-15 Pfizer Inc. CTLA-4 vastased inimese monoklonaalsed antikehad
US6824780B1 (en) * 1999-10-29 2004-11-30 Genentech, Inc. Anti-tumor antibody compositions and methods of use
US6682902B2 (en) 1999-12-16 2004-01-27 Schering Aktiengesellschaft DNA encoding a novel RG1 polypeptide

Also Published As

Publication number Publication date
EP1237915B1 (en) 2009-08-26
US20090214422A1 (en) 2009-08-27
CN1297566C (zh) 2007-01-31
US7893217B2 (en) 2011-02-22
SI1237915T1 (sl) 2009-12-31
US7887804B2 (en) 2011-02-15
ATE440862T1 (de) 2009-09-15
LT2002070A (en) 2003-04-25
NO20022836L (no) 2002-08-15
MEP37808A (en) 2011-05-10
SK288147B6 (sk) 2013-12-02
HUP0204224A3 (en) 2004-12-28
EE200200323A (et) 2003-10-15
ZA200205638B (en) 2003-10-15
HUP0204224A2 (hu) 2003-03-28
JP4979867B2 (ja) 2012-07-18
EE05293B1 (et) 2010-04-15
JP2003521244A (ja) 2003-07-15
BG65898B1 (bg) 2010-04-30
EP2048157A1 (en) 2009-04-15
DK1237915T3 (da) 2009-11-16
HRP20020549A2 (en) 2004-04-30
US7307154B2 (en) 2007-12-11
EP1237915A2 (en) 2002-09-11
SI21140A (sl) 2003-08-31
MXPA02005914A (es) 2003-02-27
LT5046B (lt) 2003-08-25
YU44602A (sh) 2005-06-10
US20090292112A1 (en) 2009-11-26
SK8482002A3 (en) 2003-02-04
RU2283130C2 (ru) 2006-09-10
AU784674B2 (en) 2006-05-25
WO2001044291A3 (en) 2002-01-17
NO20022836D0 (no) 2002-06-14
CN1434832A (zh) 2003-08-06
BG106823A (bg) 2003-04-30
US20040152139A1 (en) 2004-08-05
IL150115A (en) 2013-11-28
PL207634B1 (pl) 2011-01-31
NZ519598A (en) 2004-03-26
KR20020065575A (ko) 2002-08-13
SK286384B6 (sk) 2008-08-05
DE60042836D1 (de) 2009-10-08
RU2002119208A (ru) 2004-02-27
BR0017022A (pt) 2002-11-05
CA2394574A1 (en) 2001-06-21
CZ299232B6 (cs) 2008-05-21
KR100752434B1 (ko) 2007-08-27
PL356220A1 (en) 2004-06-28
ES2331106T3 (es) 2009-12-22
PT1237915E (pt) 2009-11-04
RS50831B (sr) 2010-08-31
HU229001B1 (en) 2013-07-29
US20040023307A1 (en) 2004-02-05
EP2048157B1 (en) 2012-10-10
RO122543B1 (ro) 2009-08-28
HRP20020549B1 (hr) 2013-09-30
US20020004047A1 (en) 2002-01-10
IL150115A0 (en) 2002-12-01
AU3074601A (en) 2001-06-25
US6682902B2 (en) 2004-01-27
WO2001044291A2 (en) 2001-06-21

Similar Documents

Publication Publication Date Title
NO330924B1 (no) Isolert antistoff eller antistoffragment, immunokonjugat, anvendelse av et immunokonjugat, en terapeutisk effektiv mengde av et immunokonjugat eller et antistoff eller antistoffragment for fremstilling av preparater henholdsvis for selektiv odeleggelse av celler, behandling av en sykdomstilstand eller diagnostisering av metastaser eller prostatakreft, samt pavisningsmetode.
WO2004016733A3 (en) Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
ATE420175T1 (de) C-typ lektin transmembranantigen, das in menschlichen prostatkrebs exprimiert wird, und deren verwendungen
BR0113491A (pt) Polinucleotìdeo e polipeptìdeo isolados, vetor de expressão, célula hospedeira, proteìna de fusão, métodos para estimular e/ou expandir células t especìficas para uma protéina de tumor, para estimular uma resposta imune em um paciente, para o tratamento de um câncer em um paciente e para inibir o desenvolvimento de um câncer em um paciente, população de célula t isolada, composição, e, uso de um componente.
WO2002010382A3 (en) Trp8, trp9 and trp10, markers for cancer
ATE541052T1 (de) Varianten des prostata-stammzellen-antigens (psca) und teilsequenzen davon
BR0308953A (pt) composições, proteìna, polinucleotìdeo, método de geração de uma resposta imune, método de detecção, composição farmacêutica, anticorpo ou seu fragmento, animal transgênico, hibridoma, método de fornecimento de um agente citotóxico ou agente de diagnóstico e método de inibição do crescimento de células cancerosas
TR200001646T2 (tr) Bir salgılanmış meme kanseri proteini olan mamaglobin.
CY1113064T1 (el) Νουκλεϊνικο οξυ και αντιστοιχη πρωτεϊνη με τιτλο 184ρ1ε2 χρησιμα στη θεραπεια και ανιχνευση καρκινου
DE69935220D1 (de) Von menschlichem tumor stammendes polypeptidhormon phosphatonin
NZ516237A (en) Meth1 and meth2 polynucleotides and polypeptides
MXPA02011563A (es) Composicionesy metodos para la terapia y diagnostico de cancer de seno.
BR0312483A (pt) Anticorpos e seus usos
WO2001081577A3 (en) Dna encoding the prost 03 polypeptide
WO2002014369A3 (en) Human kininogen d5 domain polypeptides and their use
WO2002066506A3 (en) Use of casb7439 (ash2) in the immunotherapy of breast cancer
ATE501255T1 (de) 84p2a9: prostata- und hodenspezifisches protein, das sehr stark bei prostatakrebs vorkommt
NZ502270A (en) Derivatives of mammalian secretory peptide-9 for treating cancer and may be used in conjunction with cytokines
WO2001075021A3 (fr) Nouveau polypeptide, proteine humaine associee au transport de glucose 10, et polynucleotide codant pour ce polypeptide
WO2001075010A3 (fr) Nouveau polypeptide, proteine humaine de transduction nucleaire 25 contenant un domaine structurel atp/gtp, et polynucleotide codant pour ce polypeptide
WO2001075016A3 (fr) Nouveau polypeptide, tyrosinase humaine 16, et polynucleotide codant pour ce polypeptide
WO2001094540A3 (fr) Nouveau polypeptide, glycosyl hydrolase humaine 23, et polynucleotide codant ce polypeptide
WO2001075033A3 (en) A novel polypeptide, a human cell division cycle regulatory protein 9 and the polynucleotide encoding the polypeptide
WO2001083685A3 (fr) Nouveau polypeptide, proteine cap 10, et polynucleotide codant pour ce polypeptide

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees