NO330330B1 - Fremgangsmate for fremstilling av forgrenede polymerer av glykose - Google Patents
Fremgangsmate for fremstilling av forgrenede polymerer av glykose Download PDFInfo
- Publication number
- NO330330B1 NO330330B1 NO20015224A NO20015224A NO330330B1 NO 330330 B1 NO330330 B1 NO 330330B1 NO 20015224 A NO20015224 A NO 20015224A NO 20015224 A NO20015224 A NO 20015224A NO 330330 B1 NO330330 B1 NO 330330B1
- Authority
- NO
- Norway
- Prior art keywords
- starch
- glucose
- branched polymers
- minutes
- branching
- Prior art date
Links
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 68
- 239000008103 glucose Substances 0.000 title claims abstract description 68
- 229920000642 polymer Polymers 0.000 title claims abstract description 63
- 238000000034 method Methods 0.000 title claims description 26
- 238000002360 preparation method Methods 0.000 title claims description 16
- 230000008569 process Effects 0.000 title claims description 12
- 239000007864 aqueous solution Substances 0.000 claims abstract description 6
- 229920002472 Starch Polymers 0.000 claims description 75
- 235000019698 starch Nutrition 0.000 claims description 75
- 239000008107 starch Substances 0.000 claims description 54
- 102000004190 Enzymes Human genes 0.000 claims description 26
- 108090000790 Enzymes Proteins 0.000 claims description 26
- 229920000881 Modified starch Polymers 0.000 claims description 14
- 235000019426 modified starch Nutrition 0.000 claims description 14
- 241000196324 Embryophyta Species 0.000 claims description 12
- 241000195493 Cryptophyta Species 0.000 claims description 9
- 102000003925 1,4-alpha-Glucan Branching Enzyme Human genes 0.000 claims description 8
- 108090000344 1,4-alpha-Glucan Branching Enzyme Proteins 0.000 claims description 8
- 238000004519 manufacturing process Methods 0.000 claims description 8
- 239000000725 suspension Substances 0.000 claims description 8
- 229920002527 Glycogen Polymers 0.000 claims description 7
- 229940096919 glycogen Drugs 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 241000894006 Bacteria Species 0.000 claims description 5
- 244000005700 microbiome Species 0.000 claims description 4
- 241000195597 Chlamydomonas reinhardtii Species 0.000 claims description 3
- 241000588724 Escherichia coli Species 0.000 claims description 3
- 238000002955 isolation Methods 0.000 claims description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims description 2
- 230000015556 catabolic process Effects 0.000 claims 1
- 238000006731 degradation reaction Methods 0.000 claims 1
- 235000003869 genetically modified organism Nutrition 0.000 claims 1
- 238000009826 distribution Methods 0.000 abstract description 16
- 238000012360 testing method Methods 0.000 abstract description 16
- 235000000346 sugar Nutrition 0.000 abstract description 10
- 239000000047 product Substances 0.000 description 48
- 229940088598 enzyme Drugs 0.000 description 21
- 229920000945 Amylopectin Polymers 0.000 description 10
- 229920000856 Amylose Polymers 0.000 description 10
- 238000004458 analytical method Methods 0.000 description 10
- 108090000623 proteins and genes Proteins 0.000 description 10
- 238000003860 storage Methods 0.000 description 8
- 235000013305 food Nutrition 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 229920002261 Corn starch Polymers 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 6
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
- 235000019759 Maize starch Nutrition 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 229920001519 homopolymer Polymers 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 230000002378 acidificating effect Effects 0.000 description 3
- 108090000637 alpha-Amylases Proteins 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 239000004382 Amylase Substances 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- 230000021736 acetylation Effects 0.000 description 2
- 238000006640 acetylation reaction Methods 0.000 description 2
- 102000004139 alpha-Amylases Human genes 0.000 description 2
- 229940024171 alpha-amylase Drugs 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000011230 binding agent Substances 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000004132 cross linking Methods 0.000 description 2
- 238000005886 esterification reaction Methods 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 239000000499 gel Substances 0.000 description 2
- 238000005227 gel permeation chromatography Methods 0.000 description 2
- 239000013529 heat transfer fluid Substances 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102100037709 Desmocollin-3 Human genes 0.000 description 1
- 229920001353 Dextrin Polymers 0.000 description 1
- 239000004375 Dextrin Substances 0.000 description 1
- 239000004606 Fillers/Extenders Substances 0.000 description 1
- 108010058102 Glycogen Debranching Enzyme System Proteins 0.000 description 1
- 102000017475 Glycogen debranching enzyme Human genes 0.000 description 1
- 101000880960 Homo sapiens Desmocollin-3 Proteins 0.000 description 1
- 108010028688 Isoamylase Proteins 0.000 description 1
- 229920002774 Maltodextrin Polymers 0.000 description 1
- 239000005913 Maltodextrin Substances 0.000 description 1
- 239000004368 Modified starch Substances 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 108010065084 Phosphorylase a Proteins 0.000 description 1
- 229920001218 Pullulan Polymers 0.000 description 1
- 108020004511 Recombinant DNA Proteins 0.000 description 1
- 239000007983 Tris buffer Substances 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 238000010306 acid treatment Methods 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 230000008033 biological extinction Effects 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000011111 cardboard Substances 0.000 description 1
- 238000001311 chemical methods and process Methods 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 238000013375 chromatographic separation Methods 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010411 cooking Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 235000019425 dextrin Nutrition 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 230000032050 esterification Effects 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 238000005243 fluidization Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 238000001879 gelation Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 229940035034 maltodextrin Drugs 0.000 description 1
- 238000000691 measurement method Methods 0.000 description 1
- 238000010297 mechanical methods and process Methods 0.000 description 1
- 230000005226 mechanical processes and functions Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 239000000123 paper Substances 0.000 description 1
- -1 pharmaceutical Substances 0.000 description 1
- 235000011007 phosphoric acid Nutrition 0.000 description 1
- 238000000053 physical method Methods 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 235000019423 pullulan Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 238000010008 shearing Methods 0.000 description 1
- 238000007873 sieving Methods 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 238000011105 stabilization Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 238000010257 thawing Methods 0.000 description 1
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 238000000196 viscometry Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B30/00—Preparation of starch, degraded or non-chemically modified starch, amylose, or amylopectin
- C08B30/12—Degraded, destructured or non-chemically modified starch, e.g. mechanically, enzymatically or by irradiation; Bleaching of starch
- C08B30/18—Dextrin, e.g. yellow canari, white dextrin, amylodextrin or maltodextrin; Methods of depolymerisation, e.g. by irradiation or mechanically
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/16—Preparation of compounds containing saccharide radicals produced by the action of an alpha-1, 6-glucosidase, e.g. amylose, debranched amylopectin
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Materials Engineering (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Jellies, Jams, And Syrups (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9905523A FR2792941B1 (fr) | 1999-04-30 | 1999-04-30 | Polymeres solubles de glucose branches et leur procede d'obtention |
| PCT/FR2000/001109 WO2000066633A1 (fr) | 1999-04-30 | 2000-04-26 | Polymeres solubles de glucose branches et leur procede d'obtention |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20015224L NO20015224L (no) | 2001-10-25 |
| NO20015224D0 NO20015224D0 (no) | 2001-10-25 |
| NO330330B1 true NO330330B1 (no) | 2011-03-28 |
Family
ID=9545092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20015224A NO330330B1 (no) | 1999-04-30 | 2001-10-25 | Fremgangsmate for fremstilling av forgrenede polymerer av glykose |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1177216B1 (es) |
| JP (1) | JP4823421B2 (es) |
| KR (1) | KR100803833B1 (es) |
| CN (1) | CN1197878C (es) |
| AT (1) | ATE274525T1 (es) |
| AU (1) | AU777378B2 (es) |
| CA (1) | CA2371185C (es) |
| DE (1) | DE60013271T2 (es) |
| DK (1) | DK1177216T3 (es) |
| ES (1) | ES2226821T3 (es) |
| FR (1) | FR2792941B1 (es) |
| MX (1) | MXPA01011078A (es) |
| NO (1) | NO330330B1 (es) |
| PT (1) | PT1177216E (es) |
| WO (1) | WO2000066633A1 (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2832728B1 (fr) * | 2001-11-29 | 2004-01-30 | Roquette Freres | Procede continu de modification de l'amidon et de ses derives par enzymes de branchement |
| DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
| FR2840612B1 (fr) * | 2002-06-06 | 2005-05-06 | Roquette Freres | Polymeres solubles de glucose hautement branches et leur procede d'obtention |
| AU2003232182A1 (en) * | 2002-06-17 | 2003-12-31 | Novozymes A/S | Methods for producing dextrins using enzymes |
| DE10237442B4 (de) * | 2002-08-16 | 2004-08-19 | Fresenius Kabi Deutschland Gmbh | Hochverzweigte, niedrig substituierte Stärkeprodukte |
| WO2005014655A2 (en) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
| FR2864088B1 (fr) * | 2003-12-19 | 2006-04-28 | Roquette Freres | Polymeres solubles de glucose hautement branches |
| JP4893980B2 (ja) | 2005-04-08 | 2012-03-07 | 株式会社林原生物化学研究所 | 分岐澱粉とその製造方法並びに用途 |
| JP5349050B2 (ja) * | 2006-10-06 | 2013-11-20 | 株式会社林原 | 分岐澱粉の誘導体及びその製造方法並びに分岐澱粉の誘導体を含有する成形物 |
| WO2008044586A1 (fr) * | 2006-10-06 | 2008-04-17 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Article moulé contenant de l'amidon ramifié |
| EP1943908A1 (en) * | 2006-12-29 | 2008-07-16 | Nederlandse Organisatie voor toegepast-natuurwetenschappelijk Onderzoek TNO | Novel slowly digestible storage carbohydrate |
| JP2009124994A (ja) * | 2007-11-22 | 2009-06-11 | Akita Prefectural Univ | 分岐糖類の製造方法および飲食品 |
| EP2070951A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Method for producing a hydroxyalkyl starch derivatives with two linkers |
| EP2070950A1 (en) | 2007-12-14 | 2009-06-17 | Fresenius Kabi Deutschland GmbH | Hydroxyalkyl starch derivatives and process for their preparation |
| EP2172489A1 (en) * | 2008-09-15 | 2010-04-07 | Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO | Method for altering starch using a microbial branching enzyme |
| CN106307472B (zh) * | 2009-10-26 | 2019-10-08 | 雀巢产品有限公司 | 稳定的增稠剂制品 |
| FR2955861B1 (fr) | 2010-02-02 | 2013-03-22 | Roquette Freres | Polymeres solubles de glucose branches pour la dialyse peritoneale |
| US20140073602A9 (en) | 2010-07-09 | 2014-03-13 | Fresenius Kabi Deutschland Gmbh | Nitric oxide delivering hydroxyalkyl starch derivatives |
| WO2014003556A1 (en) | 2012-06-29 | 2014-01-03 | Coöperatie Avebe U.A. | Methods and means for coating paper by film coating |
| FR2998290B1 (fr) | 2012-11-16 | 2014-12-19 | Roquette Freres | Procede de potabilisation |
| CN103404764B (zh) * | 2013-08-23 | 2015-06-17 | 内蒙古伊利实业集团股份有限公司 | 一种抗性麦芽糊精及其制备方法 |
| FR3016877A1 (fr) | 2014-01-29 | 2015-07-31 | Roquette Freres | Procede de traitement de l'eau |
| CN104544473A (zh) * | 2014-12-08 | 2015-04-29 | 江南大学 | 一种抑制淀粉回生的生物改性方法 |
| JP6470099B2 (ja) * | 2015-04-24 | 2019-02-13 | 昭和産業株式会社 | 澱粉分解物、並びに該澱粉分解物を用いた粉飴、シラップ及び飲食品 |
| WO2018007697A1 (fr) * | 2016-07-08 | 2018-01-11 | Roquette Freres | Composition de polymère de glucose hydrogénée contenant des fibres alimentaires |
| CN115895050A (zh) * | 2022-11-17 | 2023-04-04 | 江南大学 | 一种定向调控淀粉基可食用膜性能的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454161A (en) * | 1981-02-07 | 1984-06-12 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Process for the production of branching enzyme, and a method for improving the qualities of food products therewith |
| JPS6075295A (ja) * | 1983-09-29 | 1985-04-27 | Takeda Chem Ind Ltd | 水溶性澱粉質の製造法およびこれを含有せしめる飲食物の製造法 |
| JP3107358B2 (ja) * | 1994-09-13 | 2000-11-06 | 江崎グリコ株式会社 | 環状構造を有するグルカンおよびその製造方法 |
-
1999
- 1999-04-30 FR FR9905523A patent/FR2792941B1/fr not_active Expired - Fee Related
-
2000
- 2000-04-26 EP EP00922758A patent/EP1177216B1/fr not_active Expired - Lifetime
- 2000-04-26 ES ES00922758T patent/ES2226821T3/es not_active Expired - Lifetime
- 2000-04-26 KR KR1020017013894A patent/KR100803833B1/ko not_active IP Right Cessation
- 2000-04-26 DE DE60013271T patent/DE60013271T2/de not_active Expired - Lifetime
- 2000-04-26 CN CNB008069387A patent/CN1197878C/zh not_active Expired - Fee Related
- 2000-04-26 CA CA2371185A patent/CA2371185C/fr not_active Expired - Fee Related
- 2000-04-26 AT AT00922758T patent/ATE274525T1/de active
- 2000-04-26 WO PCT/FR2000/001109 patent/WO2000066633A1/fr active IP Right Grant
- 2000-04-26 PT PT00922758T patent/PT1177216E/pt unknown
- 2000-04-26 DK DK00922758T patent/DK1177216T3/da active
- 2000-04-26 JP JP2000615661A patent/JP4823421B2/ja not_active Expired - Fee Related
- 2000-04-26 MX MXPA01011078A patent/MXPA01011078A/es active IP Right Grant
- 2000-04-26 AU AU43052/00A patent/AU777378B2/en not_active Ceased
-
2001
- 2001-10-25 NO NO20015224A patent/NO330330B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA01011078A (es) | 2002-07-22 |
| FR2792941B1 (fr) | 2001-07-27 |
| DE60013271D1 (de) | 2004-09-30 |
| FR2792941A1 (fr) | 2000-11-03 |
| JP2002543248A (ja) | 2002-12-17 |
| JP4823421B2 (ja) | 2011-11-24 |
| DE60013271T2 (de) | 2005-09-15 |
| CA2371185C (fr) | 2010-09-14 |
| AU4305200A (en) | 2000-11-17 |
| CN1197878C (zh) | 2005-04-20 |
| CN1349544A (zh) | 2002-05-15 |
| ATE274525T1 (de) | 2004-09-15 |
| NO20015224L (no) | 2001-10-25 |
| NO20015224D0 (no) | 2001-10-25 |
| KR20020010622A (ko) | 2002-02-04 |
| WO2000066633A1 (fr) | 2000-11-09 |
| DK1177216T3 (da) | 2005-01-17 |
| EP1177216B1 (fr) | 2004-08-25 |
| ES2226821T3 (es) | 2005-04-01 |
| AU777378B2 (en) | 2004-10-14 |
| PT1177216E (pt) | 2005-01-31 |
| EP1177216A1 (fr) | 2002-02-06 |
| CA2371185A1 (fr) | 2000-11-09 |
| KR100803833B1 (ko) | 2008-02-14 |
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