NO328982B1 - Nitrogenoksyd-syntase-inhibitor-fosfatsalt, fremstilling av slike, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikamenter for forebygging eller behandling av sykdom - Google Patents
Nitrogenoksyd-syntase-inhibitor-fosfatsalt, fremstilling av slike, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikamenter for forebygging eller behandling av sykdom Download PDFInfo
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- NO328982B1 NO328982B1 NO20032835A NO20032835A NO328982B1 NO 328982 B1 NO328982 B1 NO 328982B1 NO 20032835 A NO20032835 A NO 20032835A NO 20032835 A NO20032835 A NO 20032835A NO 328982 B1 NO328982 B1 NO 328982B1
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Landscapes
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0031179.5A GB0031179D0 (en) | 2000-12-21 | 2000-12-21 | Nitric oxide synthase inhibitors |
PCT/GB2001/005596 WO2002050021A1 (fr) | 2000-12-21 | 2001-12-17 | Sel phosphate inhibiteur d'oxyde nitrique synthase |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20032835D0 NO20032835D0 (no) | 2003-06-20 |
NO20032835L NO20032835L (no) | 2003-08-15 |
NO328982B1 true NO328982B1 (no) | 2010-07-05 |
Family
ID=9905536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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NO20032835A NO328982B1 (no) | 2000-12-21 | 2003-06-20 | Nitrogenoksyd-syntase-inhibitor-fosfatsalt, fremstilling av slike, farmasoytisk preparat omfattende slike samt anvendelse av slike for fremstilling av medikamenter for forebygging eller behandling av sykdom |
Country Status (19)
Country | Link |
---|---|
US (1) | US7317040B2 (fr) |
EP (1) | EP1351929A1 (fr) |
JP (1) | JP3971704B2 (fr) |
KR (1) | KR100853049B1 (fr) |
CN (1) | CN100369894C (fr) |
AR (1) | AR031944A1 (fr) |
AU (2) | AU2002222252B2 (fr) |
BR (1) | BR0116369A (fr) |
CA (1) | CA2432121C (fr) |
CZ (1) | CZ301458B6 (fr) |
GB (1) | GB0031179D0 (fr) |
HU (1) | HUP0500736A3 (fr) |
IL (1) | IL156305A0 (fr) |
MX (1) | MXPA03005698A (fr) |
NO (1) | NO328982B1 (fr) |
NZ (1) | NZ526563A (fr) |
PL (1) | PL207158B1 (fr) |
WO (1) | WO2002050021A1 (fr) |
ZA (1) | ZA200304683B (fr) |
Families Citing this family (62)
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GB0214147D0 (en) * | 2002-06-19 | 2002-07-31 | Glaxo Group Ltd | Formulations |
PL375557A1 (en) * | 2002-08-23 | 2005-11-28 | Pharmacia Corporation | Crystalline solid form of (2s-5z)-2-amino-7-(ethanimidoylamino)-2-methylhept-5-enoic acid |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
GB0316290D0 (en) | 2003-07-11 | 2003-08-13 | Glaxo Group Ltd | Novel compounds |
PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
TWI307630B (en) | 2004-07-01 | 2009-03-21 | Glaxo Group Ltd | Immunoglobulins |
GB0418045D0 (en) | 2004-08-12 | 2004-09-15 | Glaxo Group Ltd | Compounds |
WO2006072599A2 (fr) | 2005-01-10 | 2006-07-13 | Glaxo Group Limited | Nouveaux composes |
AR053346A1 (es) | 2005-03-25 | 2007-05-02 | Glaxo Group Ltd | Compuesto derivado de 8h -pirido (2,3-d) pirimidin -7 ona 2,4,8- trisustituida composicion farmaceutica y uso para preparar una composicion para tratamiento y profilxis de una enfermedad mediada por la quinasa csbp/ rk/p38 |
UY29439A1 (es) | 2005-03-25 | 2006-10-02 | Glaxo Group Ltd | Nuevos compuestos |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
PE20071068A1 (es) | 2005-12-20 | 2007-12-13 | Glaxo Group Ltd | Acido 3-(4-{[4-(4-{[3-(3,3-dimetil-1-piperidinil)propil]oxi}fenil)-1-piperidinil]carbonil}-1-naftalenil)propanoico o propenoico, sales de los mismos, como antagonistas de los receptores h1 y h3 |
MX2008013411A (es) | 2006-04-20 | 2008-11-04 | Glaxo Group Ltd | Nuevos compuestos. |
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AU2007354255A1 (en) * | 2006-11-09 | 2008-12-04 | University Of Maryland, Baltimore | Use of 5,6-dimethylxanthenone-4-acetic acid as an antimicrobial agent |
PE20081889A1 (es) | 2007-03-23 | 2009-03-05 | Smithkline Beecham Corp | Indol carboxamidas como inhibidores de ikk2 |
BRPI0912267A2 (pt) | 2008-05-23 | 2015-10-13 | Amira Pharmaceuticals Inc | sal farmaceuticamente aceitável, composição farmacêutica, artigo de fabricação, métodos para tratar asma, rinite alérgica, doença, lesões gástricas e dor, métodos para prevenir broncoconstrição e rinite alérgica, uso de um sal farmaceuticamente aceitável, e, processo para a preparação de um sal farmaceuticamente aceitável. |
ES2383246T3 (es) | 2008-06-05 | 2012-06-19 | Glaxo Group Limited | 4-amino-indazoles |
WO2009147187A1 (fr) | 2008-06-05 | 2009-12-10 | Glaxo Group Limited | Dérivés de 4-carboxamide indazole utiles en tant qu'inhibiteurs de p13 kinases |
WO2010094643A1 (fr) | 2009-02-17 | 2010-08-26 | Glaxo Group Limited | Dérivés de quinoline et applications associées dans la rhinite et l'urticaire |
US8524751B2 (en) | 2009-03-09 | 2013-09-03 | GlaxoSmithKline Intellecutual Property Development | 4-oxadiazol-2-YL-indazoles as inhibitors of P13 kinases |
WO2010102968A1 (fr) | 2009-03-10 | 2010-09-16 | Glaxo Group Limited | Dérivés d'indole comme inhibiteurs de ikk2 |
EP2408769A1 (fr) | 2009-03-17 | 2012-01-25 | Glaxo Group Limited | Dérivés de pyrimidine utilisés comme inhibiteurs de ltk |
EP2408458A1 (fr) | 2009-03-19 | 2012-01-25 | Merck Sharp&Dohme Corp. | INHIBITION INDUITE PAR ARN INTERFÉRENCE DE L'EXPRESSION DU GÈNE TRANSDUCTEUR DE SIGNAL ET ACTIVITATEUR DE TRANSCRIPTION 6 (STAT6) AU MOYEN D'UN ACIDE NUCLÉIQUE INTERFÉRENT COURT (ANsi) |
US20120016011A1 (en) | 2009-03-19 | 2012-01-19 | Merck Sharp & Dohme Corp. | RNA Interference Mediated Inhibition of Connective Tissue Growth Factor (CTGF) Gene Expression Using Short Interfering Nucleic Acid (siNA) |
CN102439151A (zh) | 2009-03-19 | 2012-05-02 | 默沙东公司 | 使用短干扰核酸(siNA)的RNA干扰介导的BTB和CNC同系物1,碱性亮氨酸拉链转录因子1(Bach1)基因表达的抑制 |
JP2012520685A (ja) | 2009-03-19 | 2012-09-10 | メルク・シャープ・エンド・ドーム・コーポレイション | 低分子干渉核酸(siNA)を用いたGATA結合タンパク質3(GATA3)遺伝子発現のRNA干渉媒介性阻害 |
WO2010111497A2 (fr) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | Inhibition à médiation par l'interférence arn de l'expression du gène de la molécule d'adhésion intercellulaire 1 (icam-1) faisant appel à de courts acides nucléiques interférents (ansi) |
WO2010111464A1 (fr) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | Inhibition par interférence arn de l'expression du gène kinase 1 de régulation du signal d'apoptose (ask1) au moyen d'un acide nucléique interférent court (ansi) |
EP2411019A2 (fr) | 2009-03-27 | 2012-02-01 | Merck Sharp&Dohme Corp. | Inhibition par interférence arn de l'expression du gène du signal transducteur et activateur de la transcription 1 (stat1) au moyen d'un acide nucléique interférent court (ansi) |
JP2012521764A (ja) | 2009-03-27 | 2012-09-20 | メルク・シャープ・エンド・ドーム・コーポレイション | 低分子干渉核酸(siNA)を用いた胸腺間質性リンパ球新生因子(TSLP)遺伝子発現のRNA干渉媒介性阻害 |
WO2010111468A2 (fr) | 2009-03-27 | 2010-09-30 | Merck Sharp & Dohme Corp. | INHIBITION PAR INTERFÉRENCE ARN DE L'EXPRESSION DU GÈNE DE LA CHAÎNE BÊTA DU FACTEUR DE CROISSANCE DES NERFS (NGFß) AU MOYEN D'UN ACIDE NUCLÉIQUE INTERFÉRENT COURT (ANSI) |
WO2010122088A1 (fr) | 2009-04-24 | 2010-10-28 | Glaxo Group Limited | Pyrazole et triazole carboxamides en tant qu'inhibiteurs du canal crac |
JP2012524755A (ja) | 2009-04-24 | 2012-10-18 | グラクソ グループ リミテッド | Cracチャネル阻害剤としてのn−ピラゾリルカルボキサミド |
US8575162B2 (en) | 2009-04-30 | 2013-11-05 | Glaxosmithkline Intellectual Property Development Limited | Compounds |
WO2011067366A1 (fr) | 2009-12-03 | 2011-06-09 | Glaxo Group Limited | Dérivés d'indazole comme inhibiteurs des pi3-kinases |
JP2013512879A (ja) | 2009-12-03 | 2013-04-18 | グラクソ グループ リミテッド | Pi3キナーゼの阻害剤としてのベンズピラゾール誘導体 |
EP2507226A1 (fr) | 2009-12-03 | 2012-10-10 | Glaxo Group Limited | Nouveaux composés |
EP2512438B1 (fr) | 2009-12-16 | 2017-01-25 | 3M Innovative Properties Company | Formulations et procédés pour le réglage de l'administration de particules d'une certaine taille dans un aérosol-doseur |
TWI375671B (en) * | 2010-03-01 | 2012-11-01 | Univ China Medical | Pharmaceutical compositions containing brazilin for inhibiting expression of cytokines of t helper cell type ii and/or inhibiting expression of chemokines and uses of the same |
WO2011110575A1 (fr) | 2010-03-11 | 2011-09-15 | Glaxo Group Limited | Dérivés de 2-[2-(benzo- ou pyrido-)thiazolylamino]-6- aminopyridine, utiles dans le traitement de maladies respiratoires, allergiques ou inflammatoires |
GB201007203D0 (en) | 2010-04-29 | 2010-06-16 | Glaxo Group Ltd | Novel compounds |
HUE026059T2 (en) | 2010-09-08 | 2016-05-30 | Glaxosmithkline Ip Dev Ltd | N- [5- [4- (5 - {[(2R, 6S) -2,6-dimethyl-4-morpholinyl] methyl} -1,3-oxazol-2-yl) -1H-indazol-6-yl ] Polymorphs and salts of 2 - (methyloxy) -3-pyridinyl] methanesulfonamide |
WO2012032065A1 (fr) | 2010-09-08 | 2012-03-15 | Glaxo Group Limited | Dérivés indazole à utiliser dans le traitement d'une infection par le virus de la grippe |
WO2012035055A1 (fr) | 2010-09-17 | 2012-03-22 | Glaxo Group Limited | Nouveaux composés |
JP2013544794A (ja) | 2010-10-21 | 2013-12-19 | グラクソ グループ リミテッド | アレルギー性障害、炎症性障害及び免疫障害に作用するピラゾール化合物 |
WO2012052458A1 (fr) | 2010-10-21 | 2012-04-26 | Glaxo Group Limited | Composés pyrazole agissant contre des états allergiques, immunitaires et inflammatoires |
GB201018124D0 (en) | 2010-10-27 | 2010-12-08 | Glaxo Group Ltd | Polymorphs and salts |
JP2012140390A (ja) * | 2011-01-06 | 2012-07-26 | Sumitomo Chemical Co Ltd | α−アミノ−γ−ブチロラクトンの製造方法 |
GB201104153D0 (en) | 2011-03-11 | 2011-04-27 | Glaxo Group Ltd | Novel compounds |
WO2012123312A1 (fr) | 2011-03-11 | 2012-09-20 | Glaxo Group Limited | Dérivés pyrido[3,4-b]pyrazine en tant qu'inhibiteurs de syk |
CN102344397B (zh) * | 2011-08-23 | 2013-09-04 | 浙江升华拜克生物股份有限公司 | 一种伐奈莫林盐酸盐的提纯方法 |
MY184292A (en) | 2013-09-22 | 2021-03-30 | Sunshine Lake Pharma Co Ltd | Substituted aminopyrimidine compounds and methods of use |
WO2015148867A1 (fr) | 2014-03-28 | 2015-10-01 | Calitor Sciences, Llc | Composés hétéroaryle substitués et procédés d'utilisation |
SG11201609276RA (en) | 2014-05-12 | 2016-12-29 | Glaxosmithkline Ip No 2 Ltd | Pharmaceutical compositions comprising danirixin for treating infectious diseases |
EP3347097B1 (fr) | 2015-09-11 | 2021-02-24 | Sunshine Lake Pharma Co., Ltd. | Dérivés d' aminopyrimidine substitués en tant que modulateurs des kinases jak, flt3 et aurora |
WO2017214159A1 (fr) * | 2016-06-06 | 2017-12-14 | The Regents Of The University Of California | Cellule hôte modifiée pour produire des lactames |
WO2019099311A1 (fr) | 2017-11-19 | 2019-05-23 | Sunshine Lake Pharma Co., Ltd. | Composés hétéroaryle substitués et leurs méthodes d'utilisation |
EP3740468A4 (fr) | 2018-01-20 | 2021-10-06 | Sunshine Lake Pharma Co., Ltd. | Composés d'aminopyrimidine substitués et procédés d'utilisation |
CN109369432B (zh) * | 2018-11-02 | 2021-06-25 | 永农生物科学有限公司 | (s)-4-氯-2-氨基丁酸酯的制备方法 |
JP2023519585A (ja) | 2020-03-26 | 2023-05-11 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | ウイルス感染を予防または治療するカテプシン阻害剤 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU692892B2 (en) | 1994-06-15 | 1998-06-18 | Wellcome Foundation Limited, The | Enzyme inhibitors |
CA2194371A1 (fr) | 1994-07-04 | 1996-01-18 | Thomas Backensfeld | Comprimes de steroides faiblement doses, contenant de l'ester d'acide gallique en tant qu'antioxydant, leur procede de fabrication et utilisation |
MY117948A (en) * | 1997-01-13 | 2004-08-30 | Glaxo Group Ltd | Nitride oxide synthase inhibitors. |
SK13012000A3 (sk) | 1998-03-11 | 2001-06-11 | G. D. Searle & Co. | Halogenované deriváty amidinoaminokyselín použiteľné ako inhibítory no-syntázy |
GB9810299D0 (en) * | 1998-05-15 | 1998-07-15 | Glaxo Group Ltd | Use of nitric oxide synthase inhibitors |
-
2000
- 2000-12-21 GB GBGB0031179.5A patent/GB0031179D0/en not_active Ceased
-
2001
- 2001-12-17 MX MXPA03005698A patent/MXPA03005698A/es active IP Right Grant
- 2001-12-17 CN CNB018227066A patent/CN100369894C/zh not_active Expired - Fee Related
- 2001-12-17 WO PCT/GB2001/005596 patent/WO2002050021A1/fr active IP Right Grant
- 2001-12-17 NZ NZ526563A patent/NZ526563A/en unknown
- 2001-12-17 CA CA002432121A patent/CA2432121C/fr not_active Expired - Fee Related
- 2001-12-17 CZ CZ20031744A patent/CZ301458B6/cs not_active IP Right Cessation
- 2001-12-17 AU AU2002222252A patent/AU2002222252B2/en not_active Ceased
- 2001-12-17 US US10/451,299 patent/US7317040B2/en not_active Expired - Fee Related
- 2001-12-17 KR KR1020037008395A patent/KR100853049B1/ko not_active IP Right Cessation
- 2001-12-17 IL IL15630501A patent/IL156305A0/xx unknown
- 2001-12-17 HU HU0500736A patent/HUP0500736A3/hu unknown
- 2001-12-17 BR BR0116369-8A patent/BR0116369A/pt not_active Application Discontinuation
- 2001-12-17 AU AU2225202A patent/AU2225202A/xx active Pending
- 2001-12-17 PL PL364833A patent/PL207158B1/pl not_active IP Right Cessation
- 2001-12-17 JP JP2002551520A patent/JP3971704B2/ja not_active Expired - Fee Related
- 2001-12-17 EP EP01271352A patent/EP1351929A1/fr not_active Withdrawn
- 2001-12-19 AR ARP010105911A patent/AR031944A1/es unknown
-
2003
- 2003-06-17 ZA ZA200304683A patent/ZA200304683B/en unknown
- 2003-06-20 NO NO20032835A patent/NO328982B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1351929A1 (fr) | 2003-10-15 |
AU2002222252B2 (en) | 2005-02-24 |
ZA200304683B (en) | 2004-09-17 |
HUP0500736A3 (en) | 2009-12-28 |
JP2004516278A (ja) | 2004-06-03 |
AR031944A1 (es) | 2003-10-08 |
KR20030066737A (ko) | 2003-08-09 |
CA2432121A1 (fr) | 2002-06-27 |
NO20032835D0 (no) | 2003-06-20 |
WO2002050021A1 (fr) | 2002-06-27 |
CZ301458B6 (cs) | 2010-03-10 |
BR0116369A (pt) | 2003-10-28 |
PL207158B1 (pl) | 2010-11-30 |
IL156305A0 (en) | 2004-01-04 |
US20040087654A1 (en) | 2004-05-06 |
PL364833A1 (en) | 2004-12-27 |
CN1527814A (zh) | 2004-09-08 |
CZ20031744A3 (cs) | 2004-01-14 |
HUP0500736A2 (hu) | 2005-11-28 |
CN100369894C (zh) | 2008-02-20 |
GB0031179D0 (en) | 2001-01-31 |
NO20032835L (no) | 2003-08-15 |
CA2432121C (fr) | 2009-12-01 |
US7317040B2 (en) | 2008-01-08 |
JP3971704B2 (ja) | 2007-09-05 |
AU2225202A (en) | 2002-07-01 |
NZ526563A (en) | 2004-11-26 |
KR100853049B1 (ko) | 2008-08-19 |
MXPA03005698A (es) | 2003-10-06 |
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