NO324880B1 - Tuberkulose-antigener og fusjonsproteiner omfattende disse, DNA som koder for antigenene og ekspresjonsvektorer og vertsceller omfattende dette DNA, samt farmasoytiske sammensetninger og vaksiner for immunoterapi og diagnose av tuberkulose. - Google Patents
Tuberkulose-antigener og fusjonsproteiner omfattende disse, DNA som koder for antigenene og ekspresjonsvektorer og vertsceller omfattende dette DNA, samt farmasoytiske sammensetninger og vaksiner for immunoterapi og diagnose av tuberkulose. Download PDFInfo
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- NO324880B1 NO324880B1 NO19995689A NO995689A NO324880B1 NO 324880 B1 NO324880 B1 NO 324880B1 NO 19995689 A NO19995689 A NO 19995689A NO 995689 A NO995689 A NO 995689A NO 324880 B1 NO324880 B1 NO 324880B1
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- tuberculosis
- seq
- polypeptide
- dna
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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Applications Claiming Priority (3)
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| US85938197A | 1997-05-20 | 1997-05-20 | |
| US09/073,010 US6613881B1 (en) | 1997-05-20 | 1998-05-05 | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
| PCT/US1998/010407 WO1998053075A2 (en) | 1997-05-20 | 1998-05-20 | Compounds for immunotherapy and diagnosis of tuberculosis and methods of their use |
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| NO995689D0 NO995689D0 (no) | 1999-11-19 |
| NO995689L NO995689L (no) | 2000-01-18 |
| NO324880B1 true NO324880B1 (no) | 2007-12-27 |
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| NO19995689A NO324880B1 (no) | 1997-05-20 | 1999-11-19 | Tuberkulose-antigener og fusjonsproteiner omfattende disse, DNA som koder for antigenene og ekspresjonsvektorer og vertsceller omfattende dette DNA, samt farmasoytiske sammensetninger og vaksiner for immunoterapi og diagnose av tuberkulose. |
| NO20075900A NO20075900L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunterapi og diagnose av tuberkulose og metoder for deres anvendelse |
| NO20075902A NO20075902L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunoterapi og diagnose av turberkolose og metoder for deres anvendelse |
| NO20075901A NO20075901L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunterapi og diagnose av tuberkolose og metoder for deres anvendelse |
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| NO20075900A NO20075900L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunterapi og diagnose av tuberkulose og metoder for deres anvendelse |
| NO20075902A NO20075902L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunoterapi og diagnose av turberkolose og metoder for deres anvendelse |
| NO20075901A NO20075901L (no) | 1997-05-20 | 2007-11-15 | Forbindelser for immunterapi og diagnose av tuberkolose og metoder for deres anvendelse |
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| US (1) | US6613881B1 (ja) |
| EP (4) | EP2270170B1 (ja) |
| JP (4) | JP4162155B2 (ja) |
| KR (4) | KR100652513B1 (ja) |
| AT (1) | ATE420180T1 (ja) |
| AU (1) | AU742751B2 (ja) |
| BR (1) | BR9809445A (ja) |
| CA (2) | CA2783134A1 (ja) |
| CZ (2) | CZ303194B6 (ja) |
| DE (1) | DE69840449D1 (ja) |
| DK (1) | DK1012293T3 (ja) |
| ES (1) | ES2321039T3 (ja) |
| HU (1) | HU226520B1 (ja) |
| IL (2) | IL133056A0 (ja) |
| NO (4) | NO324880B1 (ja) |
| NZ (1) | NZ501310A (ja) |
| PL (1) | PL191121B1 (ja) |
| PT (1) | PT1012293E (ja) |
| TR (1) | TR200000115T2 (ja) |
| WO (1) | WO1998053075A2 (ja) |
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| US6991797B2 (en) | 1993-07-02 | 2006-01-31 | Statens Serum Institut | M. tuberculosis antigens |
| US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6592877B1 (en) * | 1995-09-01 | 2003-07-15 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| US6458366B1 (en) | 1995-09-01 | 2002-10-01 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| US6982085B2 (en) | 1997-04-02 | 2006-01-03 | Statens Serum Institut | TB diagnostic based on antigens from M. tuberculosis |
| US7037510B2 (en) | 1997-04-18 | 2006-05-02 | Statens Serum Institut | Hybrids of M. tuberculosis antigens |
| PT1003850E (pt) * | 1997-06-06 | 2009-08-13 | Dynavax Tech Corp | Inibidores da actividade de sequências de adn imunoestimulantes |
| EP1029053A1 (en) * | 1997-11-10 | 2000-08-23 | Statens Seruminstitut | Nucleic acid fragments and polypeptide fragments derived from mycobacterium tuberculosis |
| DE69941545D1 (de) | 1998-11-04 | 2009-11-26 | Isis Innovation | Tuberkulose diagnose test |
| US20030027774A1 (en) * | 1999-03-18 | 2003-02-06 | Ronald C. Hendrickson | Tuberculosis antigens and methods of use therefor |
| US8143386B2 (en) * | 1999-04-07 | 2012-03-27 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis antigens and their uses |
| CA2378763A1 (en) | 1999-07-13 | 2001-01-18 | Statens Serum Institut | Tuberculosis vaccine and diagnostics based on the mycobacterium tuberculosis esat-6 gene family |
| WO2001024820A1 (en) | 1999-10-07 | 2001-04-12 | Corixa Corporation | Fusion proteins of mycobacterium tuberculosis |
| US6316205B1 (en) | 2000-01-28 | 2001-11-13 | Genelabs Diagnostics Pte Ltd. | Assay devices and methods of analyte detection |
| AU2001241738A1 (en) * | 2000-02-25 | 2001-09-03 | Corixa Corporation | Compounds and methods for diagnosis and immunotherapy of tuberculosis |
| EP1278769A2 (en) * | 2000-04-19 | 2003-01-29 | Statens Serum Institut | Tuberculosis antigens and methods of use thereof |
| SI1542732T1 (sl) * | 2000-06-20 | 2010-01-29 | Corixa Corp Csc The United Sta | Fuzijski proteini Mycobacterium tuberculosis |
| US7026465B2 (en) * | 2002-02-15 | 2006-04-11 | Corixa Corporation | Fusion proteins of Mycobacterium tuberculosis |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| WO2005118884A1 (en) * | 2004-05-28 | 2005-12-15 | The United States Of America As Represented By The Secretary Of The Navy | A method for the rapid diagnosis of infectious disease by detection and quantitation of microorganism induced cytokines |
| US8475735B2 (en) * | 2004-11-01 | 2013-07-02 | Uma Mahesh Babu | Disposable immunodiagnostic test system |
| SG159555A1 (en) * | 2004-11-16 | 2010-03-30 | Crucell Holland Bv | Multivalent vaccines comprising recombinant viral vectors |
| CA2606962A1 (en) * | 2005-04-29 | 2006-11-09 | Fusion Antibodies Limited | Assays for diagnosis of tuberculosis and uses thereof |
| CN101365714A (zh) | 2005-07-01 | 2009-02-11 | 福赛特儿童口腔医院 | 结核抗原的检测分析及疫苗 |
| WO2007041539A1 (en) * | 2005-09-30 | 2007-04-12 | Transcutaneous Technologies, Inc. | Iontophoresis apparatus and method for the diagnosis of tuberculosis |
| BRPI0708912B8 (pt) | 2006-03-14 | 2021-07-27 | Univ Oregon Health & Science | métodos in vitro para detecção de mycobacterium tuberculosis e de células t expressando cd8 que especificamente reconhecem seq id no: 11 em um indivíduo |
| KR20110060891A (ko) | 2008-07-25 | 2011-06-08 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 신규한 조성물 및 방법 |
| PT2315773T (pt) * | 2008-07-25 | 2016-11-23 | Glaxosmithkline Biologicals Sa | Polipéptidos, polinucleótidos e composições para utilização no tratamento de tuberculose latente |
| HUE039159T2 (hu) | 2008-07-25 | 2018-12-28 | Glaxosmithkline Biologicals Sa | Tuberkulózis Rv2386c protein, ezt tartalmazó készítmények és ezek alkalmazása |
| KR20120129927A (ko) | 2010-01-27 | 2012-11-28 | 글락소 그룹 리미티드 | 변형된 투베르쿨로시스 항원 |
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| US4751180A (en) | 1985-03-28 | 1988-06-14 | Chiron Corporation | Expression using fused genes providing for protein product |
| US4689397A (en) | 1985-08-12 | 1987-08-25 | Scripps Clinic And Research Foundation | Synthetic polypeptides for detecting mycobacterial infections |
| US4935233A (en) | 1985-12-02 | 1990-06-19 | G. D. Searle And Company | Covalently linked polypeptide cell modulators |
| US4879213A (en) | 1986-12-05 | 1989-11-07 | Scripps Clinic And Research Foundation | Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse |
| US4976958A (en) * | 1987-02-26 | 1990-12-11 | Scripps Clinic And Research Foundation | Mycobacterial recombinants and peptides |
| US4952395A (en) | 1987-02-26 | 1990-08-28 | Scripps Clinic And Research Foundation | Mycobacterial recombinants and peptides |
| US6037135A (en) * | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
| US5330754A (en) | 1992-06-29 | 1994-07-19 | Archana Kapoor | Membrane-associated immunogens of mycobacteria |
| JPH09510866A (ja) * | 1993-12-23 | 1997-11-04 | アグリサーチ ニュージーランド パストラル アグリカルチャー リサーチ インスティテュート，リミテッド | ミコバクテリア毒力因子およびその同定のための方法 |
| AU706367B2 (en) * | 1995-03-13 | 1999-06-17 | Astra Aktiebolag | New DNA molecules |
| US6290969B1 (en) * | 1995-09-01 | 2001-09-18 | Corixa Corporation | Compounds and methods for immunotherapy and diagnosis of tuberculosis |
| DE69637879D1 (de) | 1995-09-01 | 2009-04-30 | Corixa Corp | Verbindungen und Verfahren zur Immuntherapie und Diagnose von Tuberkulose |
| WO1997009429A2 (en) | 1995-09-01 | 1997-03-13 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
| EP0934415A2 (en) * | 1996-10-11 | 1999-08-11 | Corixa Corporation | Compounds and methods for diagnosis of tuberculosis |
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