NO324401B1 - Fremgangsmate for rensing av erytropoietiner. - Google Patents
Fremgangsmate for rensing av erytropoietiner. Download PDFInfo
- Publication number
- NO324401B1 NO324401B1 NO19982085A NO982085A NO324401B1 NO 324401 B1 NO324401 B1 NO 324401B1 NO 19982085 A NO19982085 A NO 19982085A NO 982085 A NO982085 A NO 982085A NO 324401 B1 NO324401 B1 NO 324401B1
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- Prior art keywords
- heparin
- erythropoietins
- specified
- buffer
- erythropoietin
- Prior art date
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- 239000000262 estrogen Substances 0.000 description 1
- 102000015694 estrogen receptors Human genes 0.000 description 1
- 108010038795 estrogen receptors Proteins 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 229940126864 fibroblast growth factor Drugs 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000005227 gel permeation chromatography Methods 0.000 description 1
- 238000007429 general method Methods 0.000 description 1
- 230000013595 glycosylation Effects 0.000 description 1
- 238000006206 glycosylation reaction Methods 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 229920006158 high molecular weight polymer Polymers 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 210000003630 histaminocyte Anatomy 0.000 description 1
- 108091008039 hormone receptors Proteins 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 210000003000 inclusion body Anatomy 0.000 description 1
- 239000003999 initiator Substances 0.000 description 1
- 239000003456 ion exchange resin Substances 0.000 description 1
- 229920003303 ion-exchange polymer Polymers 0.000 description 1
- 238000001155 isoelectric focusing Methods 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 239000002523 lectin Substances 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 210000005229 liver cell Anatomy 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 230000035800 maturation Effects 0.000 description 1
- 201000001441 melanoma Diseases 0.000 description 1
- 235000006109 methionine Nutrition 0.000 description 1
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 1
- 239000008108 microcrystalline cellulose Substances 0.000 description 1
- 229940016286 microcrystalline cellulose Drugs 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 210000000663 muscle cell Anatomy 0.000 description 1
- ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 description 1
- 210000003061 neural cell Anatomy 0.000 description 1
- 210000004498 neuroglial cell Anatomy 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 102000044158 nucleic acid binding protein Human genes 0.000 description 1
- 108700020942 nucleic acid binding protein Proteins 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- QYSGYZVSCZSLHT-UHFFFAOYSA-N octafluoropropane Chemical compound FC(F)(F)C(F)(F)C(F)(F)F QYSGYZVSCZSLHT-UHFFFAOYSA-N 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 239000011236 particulate material Substances 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 229920001467 poly(styrenesulfonates) Polymers 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 230000000581 polycythemic effect Effects 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 230000004481 post-translational protein modification Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000004627 regenerated cellulose Substances 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 210000001995 reticulocyte Anatomy 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 210000004116 schwann cell Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000003001 serine protease inhibitor Substances 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 210000001082 somatic cell Anatomy 0.000 description 1
- 239000002594 sorbent Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000002798 spectrophotometry method Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000003934 vacuole Anatomy 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 239000011534 wash buffer Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55523995A | 1995-11-08 | 1995-11-08 | |
PCT/US1996/016711 WO1997017366A1 (en) | 1995-11-08 | 1996-10-17 | Heparin chromatography of erythropoietins |
Publications (3)
Publication Number | Publication Date |
---|---|
NO982085D0 NO982085D0 (no) | 1998-05-07 |
NO982085L NO982085L (no) | 1998-06-26 |
NO324401B1 true NO324401B1 (no) | 2007-10-01 |
Family
ID=24216519
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19982085A NO324401B1 (no) | 1995-11-08 | 1998-05-07 | Fremgangsmate for rensing av erytropoietiner. |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP0862581B1 (sk) |
JP (1) | JP3407261B2 (sk) |
KR (1) | KR19990067374A (sk) |
CN (1) | CN1200948C (sk) |
AR (1) | AR004543A1 (sk) |
AT (1) | ATE242266T1 (sk) |
AU (1) | AU704509B2 (sk) |
CA (1) | CA2236206C (sk) |
DE (2) | DE69628581T2 (sk) |
DK (1) | DK0862581T3 (sk) |
ES (1) | ES2122951T3 (sk) |
HK (1) | HK1016615A1 (sk) |
HU (1) | HU225972B1 (sk) |
IL (2) | IL124317A0 (sk) |
MA (1) | MA24128A1 (sk) |
MX (1) | MX9803697A (sk) |
NO (1) | NO324401B1 (sk) |
NZ (1) | NZ321272A (sk) |
PT (1) | PT862581E (sk) |
SA (1) | SA97170803B1 (sk) |
SI (1) | SI0862581T1 (sk) |
SK (1) | SK284315B6 (sk) |
TW (1) | TW450976B (sk) |
WO (1) | WO1997017366A1 (sk) |
ZA (1) | ZA969254B (sk) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100900033B1 (ko) * | 2007-11-21 | 2009-06-01 | 한국생명공학연구원 | 인간 에리스로포이에틴의 정제방법 |
CN117420224B (zh) * | 2023-09-08 | 2024-05-07 | 华北制药金坦生物技术股份有限公司 | 一种反相高效液相色谱法检测人促红素注射液中人血白蛋白含量的方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL239896A (sk) * | 1958-06-12 |
-
1996
- 1996-10-17 JP JP51818997A patent/JP3407261B2/ja not_active Expired - Lifetime
- 1996-10-17 DK DK96936680T patent/DK0862581T3/da active
- 1996-10-17 HU HU9901876A patent/HU225972B1/hu not_active IP Right Cessation
- 1996-10-17 CN CNB961981938A patent/CN1200948C/zh not_active Expired - Fee Related
- 1996-10-17 AT AT96936680T patent/ATE242266T1/de active
- 1996-10-17 ES ES96936680T patent/ES2122951T3/es not_active Expired - Lifetime
- 1996-10-17 IL IL12431797A patent/IL124317A0/xx unknown
- 1996-10-17 SI SI9630622T patent/SI0862581T1/xx unknown
- 1996-10-17 KR KR1019980703384A patent/KR19990067374A/ko active Search and Examination
- 1996-10-17 EP EP96936680A patent/EP0862581B1/en not_active Expired - Lifetime
- 1996-10-17 CA CA002236206A patent/CA2236206C/en not_active Expired - Fee Related
- 1996-10-17 DE DE69628581T patent/DE69628581T2/de not_active Expired - Lifetime
- 1996-10-17 PT PT96936680T patent/PT862581E/pt unknown
- 1996-10-17 AU AU74543/96A patent/AU704509B2/en not_active Ceased
- 1996-10-17 IL IL12431796A patent/IL124317A/en not_active IP Right Cessation
- 1996-10-17 DE DE0862581T patent/DE862581T1/de active Pending
- 1996-10-17 NZ NZ321272A patent/NZ321272A/xx not_active IP Right Cessation
- 1996-10-17 WO PCT/US1996/016711 patent/WO1997017366A1/en active IP Right Grant
- 1996-11-04 ZA ZA969254A patent/ZA969254B/xx unknown
- 1996-11-05 MA MA24387A patent/MA24128A1/fr unknown
- 1996-11-05 TW TW085113499A patent/TW450976B/zh not_active IP Right Cessation
- 1996-11-06 AR ARP960105067A patent/AR004543A1/es active IP Right Grant
- 1996-11-07 SK SK1447-96A patent/SK284315B6/sk not_active IP Right Cessation
-
1997
- 1997-04-09 SA SA97170803A patent/SA97170803B1/ar unknown
-
1998
- 1998-05-07 NO NO19982085A patent/NO324401B1/no not_active IP Right Cessation
- 1998-05-08 MX MX9803697A patent/MX9803697A/es unknown
-
1999
- 1999-04-21 HK HK99101717A patent/HK1016615A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM1K | Lapsed by not paying the annual fees |