NO322278B1 - Loselig CTLA4-molekyl blanding omfattende CTLA4-molekylet, anvendelse derav og in vitro fremgangsmate som involverer CTLA4-molekylet. - Google Patents
Loselig CTLA4-molekyl blanding omfattende CTLA4-molekylet, anvendelse derav og in vitro fremgangsmate som involverer CTLA4-molekylet. Download PDFInfo
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- NO322278B1 NO322278B1 NO19951436A NO951436A NO322278B1 NO 322278 B1 NO322278 B1 NO 322278B1 NO 19951436 A NO19951436 A NO 19951436A NO 951436 A NO951436 A NO 951436A NO 322278 B1 NO322278 B1 NO 322278B1
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- ctla4
- cells
- amino acid
- ctla4ig
- cell
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/228,208 US6090914A (en) | 1991-06-27 | 1994-04-15 | CTLA4/CD28Ig hybrid fusion proteins and uses thereof |
Publications (3)
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| NO951436D0 NO951436D0 (no) | 1995-04-12 |
| NO951436L NO951436L (no) | 1995-10-16 |
| NO322278B1 true NO322278B1 (no) | 2006-09-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| NO19951436A NO322278B1 (no) | 1994-04-15 | 1995-04-12 | Loselig CTLA4-molekyl blanding omfattende CTLA4-molekylet, anvendelse derav og in vitro fremgangsmate som involverer CTLA4-molekylet. |
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| Country | Link |
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| US (1) | US6090914A (fi) |
| EP (2) | EP1666498A3 (fi) |
| JP (2) | JPH0847391A (fi) |
| AU (1) | AU701310B2 (fi) |
| CA (1) | CA2146895C (fi) |
| FI (2) | FI951801A (fi) |
| IL (1) | IL113343A (fi) |
| NO (1) | NO322278B1 (fi) |
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| US6685941B1 (en) * | 1988-11-23 | 2004-02-03 | The Regents Of The University Of Michigan | Methods of treating autoimmune disease via CTLA-4Ig |
| US6887471B1 (en) * | 1991-06-27 | 2005-05-03 | Bristol-Myers Squibb Company | Method to inhibit T cell interactions with soluble B7 |
| US5637481A (en) * | 1993-02-01 | 1997-06-10 | Bristol-Myers Squibb Company | Expression vectors encoding bispecific fusion proteins and methods of producing biologically active bispecific fusion proteins in a mammalian cell |
| US5773253A (en) | 1993-01-22 | 1998-06-30 | Bristol-Myers Squibb Company | MYPPPY variants of CTL A4 and uses thereof |
| US6824779B1 (en) * | 1993-07-26 | 2004-11-30 | Dana-Farber Cancer Institute, Inc. | Methods for inhibiting the interaction of B7-2 with its natural ligand |
| US6084067A (en) * | 1993-07-26 | 2000-07-04 | Dana-Farber Cancer Institute | CTLA4/CD28 ligands and uses therefor |
| US5855887A (en) * | 1995-07-25 | 1999-01-05 | The Regents Of The University Of California | Blockade of lymphocyte down-regulation associated with CTLA-4 signaling |
| US5811097A (en) * | 1995-07-25 | 1998-09-22 | The Regents Of The University Of California | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| US6051227A (en) * | 1995-07-25 | 2000-04-18 | The Regents Of The University Of California, Office Of Technology Transfer | Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling |
| SE9601245D0 (sv) * | 1996-03-29 | 1996-03-29 | Pharmacia Ab | Chimeric superantigens and their use |
| AU710998B2 (en) * | 1996-03-20 | 1999-10-07 | Bristol-Myers Squibb Company | Methods for inhibiting an immune response by blocking the GP39/CD40 and CTLA4 /CD28/B7 pathways and compositions for use therewith |
| TW517061B (en) * | 1996-03-29 | 2003-01-11 | Pharmacia & Amp Upjohn Ab | Modified/chimeric superantigens and their use |
| US20060034844A1 (en) * | 1996-12-04 | 2006-02-16 | The Regents Of The University Of California | Stimulation of T cells against self antigens using CTLA-4 blocking agents |
| KR19980066046A (ko) * | 1997-01-18 | 1998-10-15 | 정용훈 | 고역가의 CTLA4-Ig 융합단백질 |
| US20030219863A1 (en) * | 1997-01-31 | 2003-11-27 | Bristol-Myers Squibb Company | Soluble CTLA4 mutant molecules and uses thereof |
| AU9095498A (en) * | 1997-09-19 | 1999-04-12 | Yoshitomi Pharmaceutical Industries, Ltd. | Oligopeptide compounds |
| EP0947582A1 (en) * | 1998-03-31 | 1999-10-06 | Innogenetics N.V. | A polypeptide structure for use as a scaffold |
| US6613327B1 (en) * | 1999-07-28 | 2003-09-02 | Genetics Institute, Inc. | Methods of preventing immune-mediated abortion by inhibiting a CD28-mediated costimulatory signal |
| US7605238B2 (en) | 1999-08-24 | 2009-10-20 | Medarex, Inc. | Human CTLA-4 antibodies and their uses |
| WO2001030966A2 (en) * | 1999-10-22 | 2001-05-03 | Alexion Pharmaceuticals, Inc. | An engineered recombinant molecule that regulates humoral and cellular effector functions of the immune system |
| US7094874B2 (en) * | 2000-05-26 | 2006-08-22 | Bristol-Myers Squibb Co. | Soluble CTLA4 mutant molecules |
| JP2004503507A (ja) | 2000-06-09 | 2004-02-05 | ブリストル−マイヤーズ スクイブ カンパニー | リンパ球シグナルのブロックおよびｌｆａ−１媒介性接着のブロックによる細胞性免疫応答の調節方法 |
| KR100864120B1 (ko) | 2000-07-03 | 2008-10-16 | 브리스톨-마이어스스퀴브컴파니 | 가용성 ｃｔｌａ4 분자를 사용한 류마티스성 질환의 치료법 |
| US20040022787A1 (en) | 2000-07-03 | 2004-02-05 | Robert Cohen | Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID |
| US7754208B2 (en) * | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7829084B2 (en) * | 2001-01-17 | 2010-11-09 | Trubion Pharmaceuticals, Inc. | Binding constructs and methods for use thereof |
| US20030133939A1 (en) * | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| AU2008200400B2 (en) * | 2001-01-17 | 2012-06-07 | Aptevo Research And Development Llc | Binding domain-immunoglobulin fusion proteins |
| AU2002243905B2 (en) * | 2001-01-26 | 2007-11-08 | Emory University | Methods of inducing organ transplant tolerance and correcting hemoglobinopathies |
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| US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
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| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
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| WO1994028912A1 (en) * | 1993-06-10 | 1994-12-22 | The Regents Of The University Of Michigan | Cd28 pathway immunosuppression |
-
1994
- 1994-04-15 US US08/228,208 patent/US6090914A/en not_active Expired - Lifetime
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1995
- 1995-04-12 CA CA2146895A patent/CA2146895C/en not_active Expired - Lifetime
- 1995-04-12 IL IL113343A patent/IL113343A/en not_active IP Right Cessation
- 1995-04-12 NO NO19951436A patent/NO322278B1/no not_active IP Right Cessation
- 1995-04-13 FI FI951801A patent/FI951801A/fi not_active Application Discontinuation
- 1995-04-13 EP EP05022529A patent/EP1666498A3/en not_active Withdrawn
- 1995-04-13 EP EP95302477A patent/EP0682039A1/en not_active Withdrawn
- 1995-04-13 AU AU16458/95A patent/AU701310B2/en not_active Expired
- 1995-04-17 JP JP7115095A patent/JPH0847391A/ja not_active Withdrawn
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2004
- 2004-04-07 JP JP2004113481A patent/JP2004248677A/ja active Pending
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Also Published As
| Publication number | Publication date |
|---|---|
| EP0682039A1 (en) | 1995-11-15 |
| FI951801A (fi) | 1995-10-16 |
| IL113343A0 (en) | 1995-07-31 |
| FI120041B (fi) | 2009-06-15 |
| FI951801A0 (fi) | 1995-04-13 |
| JPH0847391A (ja) | 1996-02-20 |
| FI20041632A (fi) | 2004-12-20 |
| NO951436D0 (no) | 1995-04-12 |
| JP2004248677A (ja) | 2004-09-09 |
| NO951436L (no) | 1995-10-16 |
| AU701310B2 (en) | 1999-01-28 |
| US6090914A (en) | 2000-07-18 |
| CA2146895C (en) | 2012-08-07 |
| CA2146895A1 (en) | 1995-10-16 |
| IL113343A (en) | 2006-09-05 |
| EP1666498A3 (en) | 2012-11-28 |
| EP1666498A2 (en) | 2006-06-07 |
| AU1645895A (en) | 1995-10-26 |
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