NO322141B1 - Fremgangsmate for fremstilling av kontrastmidler - Google Patents

Fremgangsmate for fremstilling av kontrastmidler Download PDF

Info

Publication number
NO322141B1
NO322141B1 NO19990890A NO990890A NO322141B1 NO 322141 B1 NO322141 B1 NO 322141B1 NO 19990890 A NO19990890 A NO 19990890A NO 990890 A NO990890 A NO 990890A NO 322141 B1 NO322141 B1 NO 322141B1
Authority
NO
Norway
Prior art keywords
carboxylic acid
phenyl
acid derivative
amino
acylation
Prior art date
Application number
NO19990890A
Other languages
English (en)
Norwegian (no)
Other versions
NO990890D0 (no
NO990890L (no
Inventor
Odd Einar Ingvoldstad
Trygve Gulbrandsen
Lars Terje Holmaas
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Publication of NO990890D0 publication Critical patent/NO990890D0/no
Publication of NO990890L publication Critical patent/NO990890L/no
Publication of NO322141B1 publication Critical patent/NO322141B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/08Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Steroid Compounds (AREA)
  • Glass Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Hydrogenated Pyridines (AREA)
NO19990890A 1996-08-29 1999-02-25 Fremgangsmate for fremstilling av kontrastmidler NO322141B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618055.9A GB9618055D0 (en) 1996-08-29 1996-08-29 Process
PCT/GB1997/002335 WO1998008805A1 (en) 1996-08-29 1997-08-29 Process for the preparation of contrast agents

Publications (3)

Publication Number Publication Date
NO990890D0 NO990890D0 (no) 1999-02-25
NO990890L NO990890L (no) 1999-02-25
NO322141B1 true NO322141B1 (no) 2006-08-21

Family

ID=10799119

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19990890A NO322141B1 (no) 1996-08-29 1999-02-25 Fremgangsmate for fremstilling av kontrastmidler

Country Status (21)

Country Link
EP (1) EP0923537B1 (cs)
JP (1) JP4113587B2 (cs)
KR (1) KR100539647B1 (cs)
CN (1) CN1092182C (cs)
AT (1) ATE207880T1 (cs)
AU (1) AU717842B2 (cs)
BG (1) BG103288A (cs)
BR (1) BR9711358A (cs)
CA (1) CA2263426A1 (cs)
CZ (1) CZ296230B6 (cs)
DE (1) DE69707901T2 (cs)
EE (1) EE9900081A (cs)
ES (1) ES2167014T3 (cs)
GB (1) GB9618055D0 (cs)
HU (1) HUP9903852A3 (cs)
IL (1) IL128685A0 (cs)
NO (1) NO322141B1 (cs)
NZ (1) NZ334818A (cs)
PL (1) PL193698B1 (cs)
SK (1) SK26399A3 (cs)
WO (1) WO1998008805A1 (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9903109D0 (en) 1999-02-11 1999-04-07 Nycomed Imaging As Process
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
CN103058880B (zh) * 2011-10-21 2015-08-05 连云港润众制药有限公司 碘克沙醇及其合成中间体的制备方法
JP6506758B2 (ja) 2013-12-06 2019-04-24 ジーイー・ヘルスケア・アクスイェ・セルスカプ 非イオン性x線造影剤の合成における中間体を精製するための代替プロセス
JP6506759B2 (ja) * 2013-12-06 2019-04-24 ジーイー・ヘルスケア・アクスイェ・セルスカプ 非イオン性x線造影剤の合成における中間体を精製するための代替プロセス
CN104356023B (zh) * 2014-10-29 2016-04-13 武汉工程大学 一种碘曲仑的制备方法
CN118993930A (zh) * 2024-10-24 2024-11-22 南昌大学 一种碘佛醇水解物连续流合成工艺

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132530B1 (cs) * 1971-04-07 1974-08-02 Guerbet Lab Andre
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE3363423D1 (en) * 1982-10-01 1986-06-12 Nyegaard & Co As X-ray contrast agents
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
DE3689330T2 (de) * 1985-08-09 1994-05-19 Cook Imaging Corp Nichtionische polyolkontrastmittel aus ionischen kontrastmitteln.

Also Published As

Publication number Publication date
CA2263426A1 (en) 1998-03-05
JP4113587B2 (ja) 2008-07-09
NO990890D0 (no) 1999-02-25
NO990890L (no) 1999-02-25
ATE207880T1 (de) 2001-11-15
HUP9903852A2 (hu) 2000-03-28
PL193698B1 (pl) 2007-03-30
SK26399A3 (en) 2000-03-13
BR9711358A (pt) 1999-08-17
IL128685A0 (en) 2000-01-31
ES2167014T3 (es) 2002-05-01
DE69707901T2 (de) 2002-07-18
BG103288A (en) 2000-01-31
EE9900081A (et) 1999-10-15
CN1092182C (zh) 2002-10-09
CN1228762A (zh) 1999-09-15
KR20000035944A (ko) 2000-06-26
KR100539647B1 (ko) 2005-12-29
PL331821A1 (en) 1999-08-02
GB9618055D0 (en) 1996-10-09
CZ67099A3 (cs) 1999-08-11
EP0923537B1 (en) 2001-10-31
DE69707901D1 (de) 2001-12-06
JP2000517313A (ja) 2000-12-26
WO1998008805A1 (en) 1998-03-05
AU717842B2 (en) 2000-04-06
AU4026797A (en) 1998-03-19
CZ296230B6 (cs) 2006-02-15
HUP9903852A3 (en) 2001-08-28
EP0923537A1 (en) 1999-06-23
NZ334818A (en) 2000-08-25

Similar Documents

Publication Publication Date Title
US5648536A (en) Process for producing ioversol
NO322141B1 (no) Fremgangsmate for fremstilling av kontrastmidler
RU2493146C2 (ru) Способ получения йодированного контрастного агента
US5840967A (en) Process for the preparation of contrast agents
EP2917174A1 (en) Preparation of intermediates of x-ray contrast agents
AU723184B2 (en) Process for iohexol manufacture
US6274762B1 (en) Preparation of tri-iodo benzene compounds
US5177261A (en) Synthesis of ioversol using chloroacetyl chloride
JP3985034B2 (ja) ヨウ素化方法
US5371278A (en) Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
US6137006A (en) Preparation of tri-iodo benzene compounds
US5575905A (en) Iodination process
KR100567449B1 (ko) 아이오디사놀 유도체의 제조방법
EP0983227B8 (en) Preparation of tri-iodo benzene compounds
WO1993016981A1 (en) Synthesis of ioversol using a minimal excess of acetoxyacetylchloride
KR960007801B1 (ko) 비이온성 요오드 치환 x선 조영물의 제조방법

Legal Events

Date Code Title Description
MK1K Patent expired