IL128685A0 - Process for preparation of contrast agents - Google Patents

Process for preparation of contrast agents

Info

Publication number
IL128685A0
IL128685A0 IL12868597A IL12868597A IL128685A0 IL 128685 A0 IL128685 A0 IL 128685A0 IL 12868597 A IL12868597 A IL 12868597A IL 12868597 A IL12868597 A IL 12868597A IL 128685 A0 IL128685 A0 IL 128685A0
Authority
IL
Israel
Prior art keywords
carboxylic acid
preparation
contrast agents
alkylation
phenyl
Prior art date
Application number
IL12868597A
Other languages
English (en)
Original Assignee
Nycomed Imaging As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Imaging As filed Critical Nycomed Imaging As
Publication of IL128685A0 publication Critical patent/IL128685A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Glass Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Exposure Of Semiconductors, Excluding Electron Or Ion Beam Exposure (AREA)
IL12868597A 1996-08-29 1997-08-29 Process for preparation of contrast agents IL128685A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9618055.9A GB9618055D0 (en) 1996-08-29 1996-08-29 Process
PCT/GB1997/002335 WO1998008805A1 (en) 1996-08-29 1997-08-29 Process for the preparation of contrast agents

Publications (1)

Publication Number Publication Date
IL128685A0 true IL128685A0 (en) 2000-01-31

Family

ID=10799119

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12868597A IL128685A0 (en) 1996-08-29 1997-08-29 Process for preparation of contrast agents

Country Status (21)

Country Link
EP (1) EP0923537B1 (xx)
JP (1) JP4113587B2 (xx)
KR (1) KR100539647B1 (xx)
CN (1) CN1092182C (xx)
AT (1) ATE207880T1 (xx)
AU (1) AU717842B2 (xx)
BG (1) BG103288A (xx)
BR (1) BR9711358A (xx)
CA (1) CA2263426A1 (xx)
CZ (1) CZ296230B6 (xx)
DE (1) DE69707901T2 (xx)
EE (1) EE9900081A (xx)
ES (1) ES2167014T3 (xx)
GB (1) GB9618055D0 (xx)
HU (1) HUP9903852A3 (xx)
IL (1) IL128685A0 (xx)
NO (1) NO322141B1 (xx)
NZ (1) NZ334818A (xx)
PL (1) PL193698B1 (xx)
SK (1) SK26399A3 (xx)
WO (1) WO1998008805A1 (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9618056D0 (en) * 1996-08-29 1996-10-09 Nycomed Imaging As Process
GB9903109D0 (en) 1999-02-11 1999-04-07 Nycomed Imaging As Process
ITMI20010773A1 (it) * 2001-04-11 2002-10-11 Chemi Spa Processo per la produzione di ioexolo ad elevata purezza
CN100344606C (zh) * 2005-12-28 2007-10-24 江苏省原子医学研究所 一种碘昔兰的制备方法
US20110021822A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As continuous deacetylation and purification process in synthesis of non-ionic x-ray contrast agents
CN103058880B (zh) * 2011-10-21 2015-08-05 连云港润众制药有限公司 碘克沙醇及其合成中间体的制备方法
CN105793235B (zh) * 2013-12-06 2019-08-23 通用电气医疗集团股份有限公司 纯化非离子x射线造影剂合成中的中间体的备选方法
US9834504B2 (en) 2013-12-06 2017-12-05 Ge Healthcare As Alternative process for the purification of an intermediate in the synthesis of non-ionic X-ray contrast agents
CN104356023B (zh) * 2014-10-29 2016-04-13 武汉工程大学 一种碘曲仑的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2132530B1 (xx) * 1971-04-07 1974-08-02 Guerbet Lab Andre
GB1548594A (en) * 1976-06-11 1979-07-18 Nyegaard & Co As Triiodoisophthalic acid amides
DE3363423D1 (en) * 1982-10-01 1986-06-12 Nyegaard & Co As X-ray contrast agents
US4584401A (en) * 1983-10-20 1986-04-22 Biophysica Foundation Methods and compositions involving polyhydroxylated polyiodo non-ionic contrast media
JPH0813794B2 (ja) * 1985-08-09 1996-02-14 クツク イマジング，インコ−ポレイテイド イオン性コントラスト媒体からの非イオン性ポリオ−ルコントラスト媒体

Also Published As

Publication number Publication date
NZ334818A (en) 2000-08-25
GB9618055D0 (en) 1996-10-09
SK26399A3 (en) 2000-03-13
KR100539647B1 (ko) 2005-12-29
EP0923537A1 (en) 1999-06-23
HUP9903852A2 (hu) 2000-03-28
PL193698B1 (pl) 2007-03-30
BG103288A (en) 2000-01-31
PL331821A1 (en) 1999-08-02
DE69707901D1 (de) 2001-12-06
DE69707901T2 (de) 2002-07-18
CZ67099A3 (cs) 1999-08-11
AU717842B2 (en) 2000-04-06
CN1228762A (zh) 1999-09-15
NO322141B1 (no) 2006-08-21
CN1092182C (zh) 2002-10-09
NO990890L (no) 1999-02-25
EE9900081A (et) 1999-10-15
CZ296230B6 (cs) 2006-02-15
AU4026797A (en) 1998-03-19
JP4113587B2 (ja) 2008-07-09
BR9711358A (pt) 1999-08-17
HUP9903852A3 (en) 2001-08-28
NO990890D0 (no) 1999-02-25
EP0923537B1 (en) 2001-10-31
WO1998008805A1 (en) 1998-03-05
KR20000035944A (ko) 2000-06-26
ES2167014T3 (es) 2002-05-01
JP2000517313A (ja) 2000-12-26
CA2263426A1 (en) 1998-03-05
ATE207880T1 (de) 2001-11-15

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