ES2171663T3 - Nuevo procedimiento para la preparacion de nucleosidos. - Google Patents

Nuevo procedimiento para la preparacion de nucleosidos.

Info

Publication number
ES2171663T3
ES2171663T3 ES96912002T ES96912002T ES2171663T3 ES 2171663 T3 ES2171663 T3 ES 2171663T3 ES 96912002 T ES96912002 T ES 96912002T ES 96912002 T ES96912002 T ES 96912002T ES 2171663 T3 ES2171663 T3 ES 2171663T3
Authority
ES
Spain
Prior art keywords
pct
nucleosids
preparation
new procedure
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96912002T
Other languages
English (en)
Inventor
Helmut Vorbruggen
Konrad Krolikiewicz
Barbel Bennua-Skalmowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Application granted granted Critical
Publication of ES2171663T3 publication Critical patent/ES2171663T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)

Abstract

UN NUEVO PROCEDIMIENTO PARA LA SINTESIS DE NUCLEOSIDOS, CARACTERIZADO POR EL HECHO DE QUE SE HACE REACCIONAR EL AZUCAR LIBRE CON BASES HETEROCICLICAS EN PRESENCIA DE AGENTES DE SILILACION EN UN DISOLVENTE INERTE CON UN ACIDO DE LEWIS
ES96912002T 1995-04-03 1996-04-03 Nuevo procedimiento para la preparacion de nucleosidos. Expired - Lifetime ES2171663T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19513330A DE19513330A1 (de) 1995-04-03 1995-04-03 Neues Verfahren zur Herstellung von Nucleosiden

Publications (1)

Publication Number Publication Date
ES2171663T3 true ES2171663T3 (es) 2002-09-16

Family

ID=7759220

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96912002T Expired - Lifetime ES2171663T3 (es) 1995-04-03 1996-04-03 Nuevo procedimiento para la preparacion de nucleosidos.

Country Status (8)

Country Link
US (1) US5750676A (es)
EP (1) EP0763047B1 (es)
AT (1) ATE212349T1 (es)
DE (2) DE19513330A1 (es)
DK (1) DK0763047T3 (es)
ES (1) ES2171663T3 (es)
PT (1) PT763047E (es)
WO (1) WO1996031520A2 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9624482D0 (en) * 1995-12-18 1997-01-15 Zeneca Phaema S A Chemical compounds
MY164523A (en) * 2000-05-23 2017-12-29 Univ Degli Studi Cagliari Methods and compositions for treating hepatitis c virus
IL153020A0 (en) * 2000-05-26 2003-06-24 Idenix Cayman Ltd Methods and compositions for treating flaviviruses and pestiviruses
US7608600B2 (en) * 2002-06-28 2009-10-27 Idenix Pharmaceuticals, Inc. Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
NZ537662A (en) * 2002-06-28 2007-10-26 Idenix Cayman Ltd 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
BR0312278A (pt) * 2002-06-28 2007-06-19 Idenix Cayman Ltd éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
BR0316363A (pt) 2002-11-15 2005-10-04 Idenix Cayman Ltd Nucleosìdeos 2'-ramificado e mutação de flaviviridae
EP2319853B1 (en) * 2002-12-12 2014-03-12 IDENIX Pharmaceuticals, Inc. Process for the production of 2'-branched nucleosides
CN1812995A (zh) * 2003-04-28 2006-08-02 艾登尼科斯（开曼）有限公司 工业化规模的核苷合成
MXPA06000162A (es) 2003-06-30 2006-03-21 Idenix Cayman Ltd Sintesis de ?-l-2-desoxinucleosidos.
JP4516863B2 (ja) * 2005-03-11 2010-08-04 株式会社ケンウッド 音声合成装置、音声合成方法及びプログラム
CA2634749C (en) * 2005-12-23 2014-08-19 Idenix Pharmaceuticals, Inc. Process for preparing a synthetic intermediate for preparation of branched nucleosides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH541566A (de) * 1969-04-11 1973-09-15 Schering Ag Verfahren zur Herstellung von Nucleosiden
DE2508312A1 (de) * 1975-02-24 1976-09-02 Schering Ag Neues verfahren zur herstellung von nucleosiden
JPS53108986A (en) * 1977-03-02 1978-09-22 Mitsui Toatsu Chem Inc Preparation of nucleosides and nucleotides

Also Published As

Publication number Publication date
EP0763047A2 (de) 1997-03-19
ATE212349T1 (de) 2002-02-15
DE19513330A1 (de) 1996-10-10
DK0763047T3 (da) 2002-04-22
US5750676A (en) 1998-05-12
EP0763047B1 (de) 2002-01-23
DE59608635D1 (de) 2002-03-14
WO1996031520A3 (de) 1996-12-12
PT763047E (pt) 2002-07-31
WO1996031520A2 (de) 1996-10-10

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