NO322063B1 - Anvendelse av en forbindelse som i det minste partielt inhiberer aktiviteten til protein p53 for fremstilling av et farmasoytisk preparat ment for behandling og/eller prevensjon av neuro-degenerative sykdommer. - Google Patents
Anvendelse av en forbindelse som i det minste partielt inhiberer aktiviteten til protein p53 for fremstilling av et farmasoytisk preparat ment for behandling og/eller prevensjon av neuro-degenerative sykdommer. Download PDFInfo
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- NO322063B1 NO322063B1 NO19961220A NO961220A NO322063B1 NO 322063 B1 NO322063 B1 NO 322063B1 NO 19961220 A NO19961220 A NO 19961220A NO 961220 A NO961220 A NO 961220A NO 322063 B1 NO322063 B1 NO 322063B1
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Virology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9311774A FR2710846B1 (fr) | 1993-10-04 | 1993-10-04 | Compositions pharmaceutiques et leur utilisation, notamment dans le traitement des maladies neurogénératives. |
| PCT/FR1994/001142 WO1995009916A1 (fr) | 1993-10-04 | 1994-09-29 | Compositions pharmaceutiques et leur utilisation, notamment pour le traitement des maladies neurodegeneratives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO961220D0 NO961220D0 (no) | 1996-03-26 |
| NO961220L NO961220L (no) | 1996-03-26 |
| NO322063B1 true NO322063B1 (no) | 2006-08-07 |
Family
ID=9451499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19961220A NO322063B1 (no) | 1993-10-04 | 1996-03-26 | Anvendelse av en forbindelse som i det minste partielt inhiberer aktiviteten til protein p53 for fremstilling av et farmasoytisk preparat ment for behandling og/eller prevensjon av neuro-degenerative sykdommer. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7273854B1 (de) |
| EP (2) | EP1598420A3 (de) |
| JP (2) | JP3937446B2 (de) |
| AT (1) | ATE311446T1 (de) |
| AU (1) | AU698242B2 (de) |
| CA (1) | CA2173338C (de) |
| DE (1) | DE69434564T2 (de) |
| DK (1) | DK0722496T3 (de) |
| ES (1) | ES2253739T3 (de) |
| FI (1) | FI117707B (de) |
| FR (1) | FR2710846B1 (de) |
| NO (1) | NO322063B1 (de) |
| WO (1) | WO1995009916A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2736915B1 (fr) | 1995-07-19 | 1997-08-22 | Rhone Poulenc Rorer Sa | Variants de la proteine p53 et utilisations therapeutiques |
| FR2746815A1 (fr) * | 1996-03-26 | 1997-10-03 | Pasteur Institut | Sequences en amont du gene sm 22, vecteurs les contenant et leurs utilisations therapeutiques, notamment dans le traitement des maladies vasculaires |
| WO1998006753A2 (en) * | 1996-08-13 | 1998-02-19 | Trustees Of Princeton University | P53 mutant |
| US5876972A (en) * | 1996-09-23 | 1999-03-02 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Nucleic acid molecules coding for tumor suppressor proteins and methods for their isolation |
| FR2781979B1 (fr) * | 1998-08-05 | 2001-06-08 | Fond Jean Dausset Ceph | Modele animal presentant une deficience de la memoire et/ou des troubles comportementaux |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5532220A (en) | 1987-08-31 | 1996-07-02 | The Regents Of The University Of California | Genetic mechanisms of tumor suppression |
| US5672344A (en) | 1987-12-30 | 1997-09-30 | The Regents Of The University Of Michigan | Viral-mediated gene transfer system |
| US5716826A (en) | 1988-03-21 | 1998-02-10 | Chiron Viagene, Inc. | Recombinant retroviruses |
| US5087617A (en) | 1989-02-15 | 1992-02-11 | Board Of Regents, The University Of Texas System | Methods and compositions for treatment of cancer using oligonucleotides |
| AU7906691A (en) * | 1990-05-23 | 1991-12-10 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | Adeno-associated virus (aav)-based eucaryotic vectors |
| JPH06501160A (ja) * | 1990-09-17 | 1994-02-10 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 細胞の増殖をコントロールするための方法及び組成物 |
| CA2108144A1 (en) * | 1991-03-06 | 1992-09-07 | Jack A. Roth | Methods and compositions for the selective inhibition of gene expression |
| FR2675803B1 (fr) * | 1991-04-25 | 1996-09-06 | Genset Sa | Oligonucleotides fermes, antisens et sens et leurs applications. |
| US6261834B1 (en) * | 1991-11-08 | 2001-07-17 | Research Corporation Technologies, Inc. | Vector for gene therapy |
| DE69333921T2 (de) * | 1992-12-31 | 2006-08-10 | Dana-Farber Cancer Institute, Inc., Boston | "enhancer" sequenz zur modulation der expression in epithelialzellen |
| US5624803A (en) * | 1993-10-14 | 1997-04-29 | The Regents Of The University Of California | In vivo oligonucleotide generator, and methods of testing the binding affinity of triplex forming oligonucleotides derived therefrom |
| US5700657A (en) | 1993-12-13 | 1997-12-23 | Genzyme Corporation | Vectors and vector systems including genes encoding tumor suppressor proteins and producer cells transformed thereby |
| US5731172A (en) | 1994-03-09 | 1998-03-24 | Sumitomo Pharmaceuticals Company, Ltd. | Recombinant adenovirus and process for producing the same |
| US5641749A (en) | 1995-11-29 | 1997-06-24 | Amgen Inc. | Method for treating retinal ganglion cell injury using glial cell line-derived neurothrophic factor (GDNF) protein product |
| US5641750A (en) | 1995-11-29 | 1997-06-24 | Amgen Inc. | Methods for treating photoreceptors using glial cell line-derived neurotrophic factor (GDNF) protein product |
-
1993
- 1993-10-04 FR FR9311774A patent/FR2710846B1/fr not_active Expired - Lifetime
-
1994
- 1994-09-29 ES ES94928933T patent/ES2253739T3/es not_active Expired - Lifetime
- 1994-09-29 JP JP51063995A patent/JP3937446B2/ja not_active Expired - Fee Related
- 1994-09-29 EP EP05016159A patent/EP1598420A3/de not_active Withdrawn
- 1994-09-29 AU AU78162/94A patent/AU698242B2/en not_active Expired
- 1994-09-29 EP EP94928933A patent/EP0722496B1/de not_active Expired - Lifetime
- 1994-09-29 AT AT94928933T patent/ATE311446T1/de active
- 1994-09-29 CA CA002173338A patent/CA2173338C/fr not_active Expired - Lifetime
- 1994-09-29 DK DK94928933T patent/DK0722496T3/da active
- 1994-09-29 WO PCT/FR1994/001142 patent/WO1995009916A1/fr active IP Right Grant
- 1994-09-29 DE DE69434564T patent/DE69434564T2/de not_active Expired - Lifetime
-
1996
- 1996-03-26 NO NO19961220A patent/NO322063B1/no not_active IP Right Cessation
- 1996-04-03 FI FI961494A patent/FI117707B/fi not_active IP Right Cessation
-
2000
- 2000-05-26 US US09/578,453 patent/US7273854B1/en not_active Expired - Fee Related
-
2007
- 2007-01-19 JP JP2007010778A patent/JP2007190020A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NO961220D0 (no) | 1996-03-26 |
| FI961494A0 (fi) | 1996-04-03 |
| US7273854B1 (en) | 2007-09-25 |
| DE69434564T2 (de) | 2006-08-10 |
| JP3937446B2 (ja) | 2007-06-27 |
| FI117707B (fi) | 2007-01-31 |
| WO1995009916A1 (fr) | 1995-04-13 |
| NO961220L (no) | 1996-03-26 |
| AU7816294A (en) | 1995-05-01 |
| EP0722496B1 (de) | 2005-11-30 |
| FR2710846A1 (fr) | 1995-04-14 |
| EP0722496A1 (de) | 1996-07-24 |
| CA2173338C (fr) | 2009-05-05 |
| DK0722496T3 (da) | 2006-04-03 |
| DE69434564D1 (de) | 2006-01-05 |
| EP1598420A2 (de) | 2005-11-23 |
| CA2173338A1 (fr) | 1995-04-13 |
| ATE311446T1 (de) | 2005-12-15 |
| AU698242B2 (en) | 1998-10-29 |
| FI961494A (fi) | 1996-04-03 |
| EP1598420A3 (de) | 2007-12-12 |
| JPH09503915A (ja) | 1997-04-22 |
| ES2253739T3 (es) | 2006-06-01 |
| JP2007190020A (ja) | 2007-08-02 |
| FR2710846B1 (fr) | 1995-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |